NO941273L - Ny anvendelse av substituert kinolinkarboksamid - Google Patents

Ny anvendelse av substituert kinolinkarboksamid

Info

Publication number
NO941273L
NO941273L NO941273A NO941273A NO941273L NO 941273 L NO941273 L NO 941273L NO 941273 A NO941273 A NO 941273A NO 941273 A NO941273 A NO 941273A NO 941273 L NO941273 L NO 941273L
Authority
NO
Norway
Prior art keywords
compound
new use
salt
atoms
substituted quinoline
Prior art date
Application number
NO941273A
Other languages
English (en)
Other versions
NO941273D0 (no
Inventor
Oded Abramsky
Dimitrios Karussis
Dan Lehamann
Shimon Slavin
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of NO941273D0 publication Critical patent/NO941273D0/no
Publication of NO941273L publication Critical patent/NO941273L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Anvendelsen av en anti-MS-kinolin-3-forbindelse omfattende strukturen med formel (I), eventuelt med substituenter for H1"9-hydrogenatomene, eller et salt av nevnte forbindelse K7,H8 (I) hvor (a)---------betyr at det fins to konjugerte dobbelt- bindinger mellom atomer som omfattes av den stiplede linje, (b) hydrogenatomene H7 og H8 er knyttet til forskjellige atomer valgt fra X1; X2 og nitrogen- atomet i kinolinringen, (c) Xx og X2 er uavhengig valgt fra et oksygenatom eller en NH9-gruppe, og nevnte X.,^ og X2 er bundet med en enkeltbinding til ringen når de bærer H7 eller H8 og med en dobbelt- binding når de ikke bærer H7 eller H8, for fremstil- ling av en sammensetning beregnet på behandling av tilstander forbundet med MS er beskrevet. Også be- skrevet er behandlingskurer for MS-pasienter. Den spesielt foretrukne forbindelse er roquinimex eller et salt derav.
NO941273A 1991-10-09 1994-04-08 Ny anvendelse av substituert kinolinkarboksamid NO941273L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9102909A SE469368B (sv) 1991-10-09 1991-10-09 Ny anvaendning av linomide foer tillverkning av laekemedel foer behandling av multiple sclerosis (ms)
PCT/SE1992/000705 WO1993006829A1 (en) 1991-10-09 1992-10-08 New use of substituted quinoline carboxamide

Publications (2)

Publication Number Publication Date
NO941273D0 NO941273D0 (no) 1994-04-08
NO941273L true NO941273L (no) 1994-06-08

Family

ID=20383935

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941273A NO941273L (no) 1991-10-09 1994-04-08 Ny anvendelse av substituert kinolinkarboksamid

Country Status (11)

Country Link
US (1) US5580882A (no)
EP (1) EP0607282A1 (no)
JP (1) JPH06511488A (no)
KR (1) KR940702726A (no)
AU (1) AU653647B2 (no)
CA (1) CA2120712A1 (no)
EE (1) EE9400257A (no)
NO (1) NO941273L (no)
PT (1) PT100937A (no)
SE (1) SE469368B (no)
WO (1) WO1993006829A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302490D0 (sv) * 1993-07-26 1993-07-26 Kabi Pharmacia Ab New use of old drugs
SE9400810D0 (sv) * 1994-03-10 1994-03-10 Pharmacia Ab New use of Quinoline-3-carboxamide compounds
SE9400809D0 (sv) * 1994-03-10 1994-03-10 Pharmacia Ab New use of quinoline-3-carboxamide compounds
EP0685466A1 (de) * 1994-06-02 1995-12-06 Ciba-Geigy Ag 3-Heteroaliphatyl- und 3-Hetero-(aryl)aliphatyl-2(1H)-chinolonderivate
US5837815A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polypeptide products
EP0936866A4 (en) * 1996-10-28 2001-04-11 Dept Of The Army Us Government COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING ANTIBIOTIC RESIST INFECTIONS
JP4120713B2 (ja) * 1997-09-04 2008-07-16 大塚製薬株式会社 多発性硬化症治療剤
US6077851A (en) * 1998-04-27 2000-06-20 Active Biotech Ab Quinoline derivatives
SE9802550D0 (sv) * 1998-07-15 1998-07-15 Active Biotech Ab Quinoline derivatives
SE9802549D0 (sv) * 1998-07-15 1998-07-15 Active Biotech Ab Quinoline derivatives
US6133285A (en) * 1998-07-15 2000-10-17 Active Biotech Ab Quinoline derivatives
US6861442B1 (en) * 1998-12-30 2005-03-01 Sugen, Inc. PYK2 and inflammation
BR112013007850A2 (pt) * 2010-10-14 2016-06-07 Immunahr Ab 1,2-diidro-4-hidróxi-2-oxo-quinolina-3-carboxanilidas como ativadores de ahr

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52670B1 (en) * 1981-03-03 1988-01-20 Leo Ab Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
US5310913A (en) * 1989-06-09 1994-05-10 Kabi Pharmacia Aktiebolag Derivatives of quinoline-3-carboxanilide

Also Published As

Publication number Publication date
EP0607282A1 (en) 1994-07-27
PT100937A (pt) 1994-01-31
CA2120712A1 (en) 1993-04-15
AU653647B2 (en) 1994-10-06
SE469368B (sv) 1993-06-28
JPH06511488A (ja) 1994-12-22
EE9400257A (et) 1996-02-15
US5580882A (en) 1996-12-03
NO941273D0 (no) 1994-04-08
KR940702726A (ko) 1994-09-17
WO1993006829A1 (en) 1993-04-15
SE9102909D0 (sv) 1991-10-09
AU2770892A (en) 1993-05-03
SE9102909L (sv) 1993-04-10

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