NO922565L - Nye difosfonatforbindelser - Google Patents

Nye difosfonatforbindelser

Info

Publication number
NO922565L
NO922565L NO92922565A NO922565A NO922565L NO 922565 L NO922565 L NO 922565L NO 92922565 A NO92922565 A NO 92922565A NO 922565 A NO922565 A NO 922565A NO 922565 L NO922565 L NO 922565L
Authority
NO
Norway
Prior art keywords
present
relates
novel compounds
compounds
diphosphonate compounds
Prior art date
Application number
NO92922565A
Other languages
English (en)
Other versions
NO922565D0 (no
NO176144B (no
NO176144C (no
Inventor
Frank Hallock Ebetino
Kent Warren Buckingham
Jocelyn Elaine Mcosker
Original Assignee
Norwich Eaton Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO922565L publication Critical patent/NO922565L/no
Application filed by Norwich Eaton Pharma filed Critical Norwich Eaton Pharma
Priority to NO922565A priority Critical patent/NO176144C/no
Publication of NO922565D0 publication Critical patent/NO922565D0/no
Publication of NO176144B publication Critical patent/NO176144B/no
Publication of NO176144C publication Critical patent/NO176144C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/5765—Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Paints Or Removers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO922565A 1986-12-19 1992-06-29 Nye difosfonsyreforbindelser NO176144C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO922565A NO176144C (no) 1986-12-19 1992-06-29 Nye difosfonsyreforbindelser

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/945,069 US4868164A (en) 1986-12-19 1986-12-19 Octahydro-pyridine diphosphonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism
NO875305A NO174625C (no) 1986-12-19 1987-12-18 Analogifremgangsmåte for fremstilling av terapeutisk aktiv cis-oktahydro-1-pyrindin-6,6-difosfonsyre
NO922565A NO176144C (no) 1986-12-19 1992-06-29 Nye difosfonsyreforbindelser

Publications (4)

Publication Number Publication Date
NO922565L true NO922565L (no) 1988-06-20
NO922565D0 NO922565D0 (no) 1992-06-29
NO176144B NO176144B (no) 1994-10-31
NO176144C NO176144C (no) 1995-02-08

Family

ID=25482572

Family Applications (2)

Application Number Title Priority Date Filing Date
NO875305A NO174625C (no) 1986-12-19 1987-12-18 Analogifremgangsmåte for fremstilling av terapeutisk aktiv cis-oktahydro-1-pyrindin-6,6-difosfonsyre
NO922565A NO176144C (no) 1986-12-19 1992-06-29 Nye difosfonsyreforbindelser

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO875305A NO174625C (no) 1986-12-19 1987-12-18 Analogifremgangsmåte for fremstilling av terapeutisk aktiv cis-oktahydro-1-pyrindin-6,6-difosfonsyre

Country Status (18)

Country Link
US (3) US4868164A (no)
EP (1) EP0273514B1 (no)
JP (1) JP2573973B2 (no)
KR (1) KR950009196B1 (no)
AT (1) ATE59046T1 (no)
AU (1) AU615886B2 (no)
CA (1) CA1321793C (no)
DE (1) DE3766695D1 (no)
DK (1) DK171068B1 (no)
FI (1) FI87652C (no)
HK (1) HK79393A (no)
IE (1) IE873456L (no)
IL (1) IL84660A (no)
MY (1) MY102266A (no)
NO (2) NO174625C (no)
NZ (1) NZ222985A (no)
PH (1) PH25583A (no)
ZA (1) ZA879502B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868164A (en) * 1986-12-19 1989-09-19 Norwich Eaton Pharmaceuticals, Inc. Octahydro-pyridine diphosphonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism
IL86951A (en) * 1987-07-06 1996-07-23 Procter & Gamble Pharma Methylene phosphonoalkylphosphinates and pharmaceutical preparations containing them
DE3822650A1 (de) * 1988-07-05 1990-02-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
EP0642521A1 (en) * 1992-05-29 1995-03-15 Procter & Gamble Pharmaceuticals Thio-substituted nitrogen-containing heterocyclic phosphonate compounds for treating abnormal calcium and phosphate metabolism
US5753634A (en) * 1992-05-29 1998-05-19 The Procter & Gamble Company Quaternary nitrogen containing phosphonate compounds, pharmaceutical compostions, and methods for treating abnormal calcium and phosphate metabolism
AU662991B2 (en) * 1992-05-29 1995-09-21 Procter & Gamble Pharmaceuticals, Inc. Quaternary nitrogen-containing phosphonates for treating abnormal calcium and phosphate metabolism
HUT69699A (en) * 1992-05-29 1995-09-28 Procter & Gamble Pharma Sulfur-containing phosphonate compounds for treating abnormal calcium and phosphate metabolism
US5763611A (en) * 1992-05-29 1998-06-09 The Procter & Gamble Company Thio-substituted cyclic phosphonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism
US5391743A (en) * 1992-05-29 1995-02-21 Procter & Gamble Pharmaceuticals, Inc. Quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism and methods of treating and preventing dental calculus and plaque
RU2119794C1 (ru) * 1992-06-30 1998-10-10 Проктер энд Гэмбл Фармасьютикалз, Инк. Использование фосфонатов и нестероидных противовоспалительных лекарственных средств для лечения артрита, способ лечения
CA2199252A1 (en) * 1994-09-09 1996-03-14 Ann Dunbar Geddes Methods for the treatment of osteoporosis using bone active phosphonates and parathyroid hormone
EP0753523A1 (en) 1995-07-10 1997-01-15 Gador S.A. Amino-substituted bisphosphonic acids
US7781418B2 (en) * 2006-12-14 2010-08-24 Isis Innovation Ltd. Composition for treating bone disorders
US11793452B2 (en) 2019-10-03 2023-10-24 Johnson & Johnson Consumer Inc. Method of visualizing and quantifying remineralization

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3553314A (en) * 1968-12-23 1971-01-05 Procter & Gamble Oral compositions for calculus retardation
US3979385A (en) * 1969-11-19 1976-09-07 Henkel & Cie G.M.B.H. 1-Aminoalkane-1,1-diphosphonic acids and their salts
DE1958123C3 (de) * 1969-11-19 1978-09-28 Henkel Kgaa, 4000 Duesseldorf Verfahren zur Herstellung von 1 -Aminoalkan-1,1 -diphosphonsäuren oder deren Salzen
US3683080A (en) * 1970-08-28 1972-08-08 Procter & Gamble Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue
US3899496A (en) * 1970-10-06 1975-08-12 Henkel & Cie Gmbh Production of 1-aminoalkane-1,1-diphosphonic acids
DE2104476C2 (de) * 1971-02-01 1983-12-01 Henkel KGaA, 4000 Düsseldorf Verfahren zur Verhinderung von Ausfällungen in Wasser oder wäßrigen Lösungen
DE2343196C3 (de) * 1973-08-27 1980-01-10 Henkel Kgaa, 4000 Duesseldorf Aiacycloalkan-2^-diphosphonsäuren oder deren wasserlösliche Salze
US4034086A (en) * 1973-08-27 1977-07-05 Henkel & Cie G.M.B.H. Pyrrolidone-5,5-diphosphonic acids
DE2343147C2 (de) * 1973-08-27 1982-06-09 Henkel KGaA, 4000 Düsseldorf Pyrrolidon-5,5-diphosphonsäuren, deren wasserlösliche Salze, und Verfahren zu ihrer Herstellung
US3988443A (en) * 1973-08-27 1976-10-26 Henkel & Cie G.M.B.H. Azacycloalkane-2,2-diphosphonic acids
DE2456666A1 (de) * 1974-11-30 1976-08-12 Henkel & Cie Gmbh Verfahren zum stabilisieren von calcium-hydrogenphosphat-dihydrat gegen hydrolyse
DE2543349C2 (de) * 1975-09-29 1984-05-10 Henkel KGaA, 4000 Düsseldorf Preaparate zur herstellung von99m technetium-radiagnostica
SE7612534L (sv) * 1975-12-01 1977-06-02 Henkel & Cie Gmbh Forfarande for framstellning av farmaceutiska preparat for behandling av storningar i kalciumemnesomsettning
DE2745083C2 (de) * 1977-10-07 1985-05-02 Henkel KGaA, 4000 Düsseldorf Hydroxydiphosphonsäuren und Verfahren zu deren Herstellung
US4230700A (en) * 1977-12-07 1980-10-28 The Procter & Gamble Company Methods for inhibiting mobilization of calcium phosphate in animal tissue
SU1002300A1 (ru) * 1981-10-29 1983-03-07 Ордена Ленина институт элементоорганических соединений им.А.Н.Несмеянова Способ получени @ -аминозамещенных- @ -оксипропилидендифосфоновых кислот
DE3428524A1 (de) * 1984-08-02 1986-02-13 Boehringer Mannheim Gmbh, 6800 Mannheim Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4687768A (en) * 1984-12-21 1987-08-18 The Procter & Gamble Company Certain hexahydroindan-2,2-diphosphonic acids useful in treating diseases associated with abnormal calcium and phosphate metabolism
DE3540150A1 (de) * 1985-11-13 1987-05-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4868164A (en) * 1986-12-19 1989-09-19 Norwich Eaton Pharmaceuticals, Inc. Octahydro-pyridine diphosphonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism

Also Published As

Publication number Publication date
HK79393A (en) 1993-08-13
FI875595A0 (fi) 1987-12-18
IL84660A (en) 1994-10-21
DK171068B1 (da) 1996-05-20
ATE59046T1 (de) 1990-12-15
NZ222985A (en) 1990-09-26
FI875595A (fi) 1988-06-20
IE873456L (en) 1988-06-19
PH25583A (en) 1991-08-08
FI87652C (fi) 1993-02-10
US5137880A (en) 1992-08-11
FI87652B (fi) 1992-10-30
NO922565D0 (no) 1992-06-29
NO176144B (no) 1994-10-31
DK670387A (da) 1988-06-20
DE3766695D1 (de) 1991-01-24
NO176144C (no) 1995-02-08
DK670387D0 (da) 1987-12-18
EP0273514A1 (en) 1988-07-06
JP2573973B2 (ja) 1997-01-22
US5393746A (en) 1995-02-28
CA1321793C (en) 1993-08-31
US4868164A (en) 1989-09-19
NO875305D0 (no) 1987-12-18
ZA879502B (en) 1988-06-16
AU8280987A (en) 1988-06-23
IL84660A0 (en) 1988-04-29
MY102266A (en) 1992-05-15
NO174625C (no) 1994-06-08
KR950009196B1 (ko) 1995-08-16
AU615886B2 (en) 1991-10-17
EP0273514B1 (en) 1990-12-12
KR880007473A (ko) 1988-08-27
NO174625B (no) 1994-02-28
JPS63239290A (ja) 1988-10-05
NO875305L (no) 1988-06-20

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NO922565L (no) Nye difosfonatforbindelser
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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees