NO882281L - Fremgangsmaate for fremstilling av terapeutisk aktive pyrazinamider. - Google Patents
Fremgangsmaate for fremstilling av terapeutisk aktive pyrazinamider.Info
- Publication number
- NO882281L NO882281L NO882281A NO882281A NO882281L NO 882281 L NO882281 L NO 882281L NO 882281 A NO882281 A NO 882281A NO 882281 A NO882281 A NO 882281A NO 882281 L NO882281 L NO 882281L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- pyrazinamides
- preparation
- bromine
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/16—Halogen atoms; Nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878712365A GB8712365D0 (en) | 1987-05-26 | 1987-05-26 | Aminomethylphenolic pyrazines |
| GB888804983A GB8804983D0 (en) | 1988-03-02 | 1988-03-02 | Heterocyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO882281D0 NO882281D0 (no) | 1988-05-25 |
| NO882281L true NO882281L (no) | 1988-11-28 |
Family
ID=26292286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO882281A NO882281L (no) | 1987-05-26 | 1988-05-25 | Fremgangsmaate for fremstilling av terapeutisk aktive pyrazinamider. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4910202A (fr) |
| EP (1) | EP0293170A1 (fr) |
| JP (1) | JPS6456668A (fr) |
| KR (1) | KR880013904A (fr) |
| CN (1) | CN88103114A (fr) |
| AU (1) | AU1634588A (fr) |
| DK (1) | DK288888A (fr) |
| FI (1) | FI882482A (fr) |
| GB (1) | GB8810933D0 (fr) |
| HU (1) | HU199129B (fr) |
| NO (1) | NO882281L (fr) |
| PL (1) | PL272681A1 (fr) |
| PT (1) | PT87572B (fr) |
| ZW (1) | ZW6388A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8810934D0 (en) * | 1987-05-26 | 1988-06-15 | Ici America Inc | Amides |
| US5739211A (en) * | 1997-02-25 | 1998-04-14 | The Goodyear Tire & Rubber Company | Rubber compositions containing a pyrazine amide |
| EP1131634A2 (fr) * | 1998-09-30 | 2001-09-12 | Elan Pharmaceuticals, Inc. | Reactifs biologiques et procedes servant a determiner le mecanisme implique dans la generation du peptide beta-amyloide |
| CA2727196A1 (fr) * | 2008-06-10 | 2009-12-17 | Novartis Ag | Composes organiques |
| UY36034A (es) | 2014-03-18 | 2015-09-30 | Astrazeneca Ab | Derivados de 3,5-diamino-6-cloro-pirazina-2-carboxamida y sales farmaceuticamente aceptables de estos |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3305552A (en) * | 1965-11-22 | 1967-02-21 | Merck & Co Inc | 3-aminopyrazinoic acids and process for their preparation |
| NL6707566A (fr) * | 1966-08-17 | 1968-02-19 | ||
| US3555024A (en) * | 1968-11-13 | 1971-01-12 | Merck & Co Inc | 1-(3-aminopyrazinoyl)semicarbazides,1-(3-aminopyrazinoyl) - thiosemicarbazides,and method for their preparation |
| US3567725A (en) * | 1968-11-20 | 1971-03-02 | Merck & Co Inc | Process for preparation of 1h-imidazo-(4,5-b)pyrazin-2-ones |
| US3577418A (en) * | 1969-02-12 | 1971-05-04 | Merck & Co Inc | Pyrazinamide derivatives and processes for their preparation |
| US3544568A (en) * | 1969-03-18 | 1970-12-01 | Merck & Co Inc | 3-amino-5,6-substituted pyrazinamides |
| US3809721A (en) * | 1970-12-23 | 1974-05-07 | Merck & Co Inc | Substituted 2-aminomethyl-4,6-disubstituted phenols |
| US4041032A (en) * | 1974-01-16 | 1977-08-09 | Yamanouchi Pharmaceutical Co., Ltd. | Pyrazine derivatives |
| US3928624A (en) * | 1974-04-25 | 1975-12-23 | Merck & Co Inc | Phenol compounds in treating pain, fever and inflammation |
| US4029816A (en) * | 1975-11-25 | 1977-06-14 | Merck & Co., Inc. | Substituted 2-aminomethyl-6-iodophenols |
| US4085211A (en) * | 1975-12-15 | 1978-04-18 | Merck & Co., Inc. | Pyrazinecarboxamides and processes for preparing same |
| US4115573A (en) * | 1977-03-04 | 1978-09-19 | Merck & Co., Inc. | N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidine and processes for preparing same |
| US4272537A (en) * | 1980-07-02 | 1981-06-09 | Merck & Co., Inc. | 3-Amino-5-substituted-6-halo-N-(4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides |
| IE52345B1 (en) * | 1981-02-02 | 1987-09-16 | Ici Plc | Alkanolamine derivatives |
| EP0086564B1 (fr) * | 1982-01-29 | 1985-11-21 | Imperial Chemical Industries Plc | Dérivés d'alkanolamine |
-
1988
- 1988-05-09 GB GB888810933A patent/GB8810933D0/en active Pending
- 1988-05-16 ZW ZW63/88A patent/ZW6388A1/xx unknown
- 1988-05-17 AU AU16345/88A patent/AU1634588A/en not_active Abandoned
- 1988-05-24 EP EP88304696A patent/EP0293170A1/fr not_active Ceased
- 1988-05-25 PT PT87572A patent/PT87572B/pt not_active IP Right Cessation
- 1988-05-25 NO NO882281A patent/NO882281L/no unknown
- 1988-05-25 PL PL27268188A patent/PL272681A1/xx unknown
- 1988-05-25 HU HU882649A patent/HU199129B/hu not_active IP Right Cessation
- 1988-05-26 FI FI882482A patent/FI882482A/fi not_active Application Discontinuation
- 1988-05-26 KR KR1019880006198A patent/KR880013904A/ko not_active Application Discontinuation
- 1988-05-26 CN CN198888103114A patent/CN88103114A/zh active Pending
- 1988-05-26 DK DK288888A patent/DK288888A/da not_active Application Discontinuation
- 1988-05-26 US US07/198,946 patent/US4910202A/en not_active Expired - Fee Related
- 1988-05-26 JP JP63129418A patent/JPS6456668A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US4910202A (en) | 1990-03-20 |
| HU199129B (en) | 1990-01-29 |
| GB8810933D0 (en) | 1988-06-15 |
| FI882482A0 (fi) | 1988-05-26 |
| CN88103114A (zh) | 1988-12-28 |
| DK288888A (da) | 1988-11-27 |
| DK288888D0 (da) | 1988-05-26 |
| ZW6388A1 (en) | 1989-12-20 |
| PT87572A (pt) | 1989-05-31 |
| NO882281D0 (no) | 1988-05-25 |
| PT87572B (pt) | 1992-09-30 |
| AU1634588A (en) | 1988-12-01 |
| FI882482A (fi) | 1988-11-27 |
| EP0293170A1 (fr) | 1988-11-30 |
| JPS6456668A (en) | 1989-03-03 |
| PL272681A1 (en) | 1989-02-06 |
| KR880013904A (ko) | 1988-12-22 |
| HUT47918A (en) | 1989-04-28 |
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