NO300267B1 - Akridin-derivater, samt anvendelse av slike i farmasöytiske preparater - Google Patents

Akridin-derivater, samt anvendelse av slike i farmasöytiske preparater Download PDF

Info

Publication number
NO300267B1
NO300267B1 NO932512A NO932512A NO300267B1 NO 300267 B1 NO300267 B1 NO 300267B1 NO 932512 A NO932512 A NO 932512A NO 932512 A NO932512 A NO 932512A NO 300267 B1 NO300267 B1 NO 300267B1
Authority
NO
Norway
Prior art keywords
dihydro
oxo
methyl
acridinecarboxamide
phenyl
Prior art date
Application number
NO932512A
Other languages
English (en)
Norwegian (no)
Other versions
NO932512L (no
NO932512D0 (no
Inventor
Bernard Andre Dumaitre
Nerina Dodic
Original Assignee
Glaxo Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919100637A external-priority patent/GB9100637D0/en
Priority claimed from GB919100628A external-priority patent/GB9100628D0/en
Priority claimed from GB919115981A external-priority patent/GB9115981D0/en
Priority claimed from GB919115956A external-priority patent/GB9115956D0/en
Application filed by Glaxo Lab Sa filed Critical Glaxo Lab Sa
Publication of NO932512D0 publication Critical patent/NO932512D0/no
Publication of NO932512L publication Critical patent/NO932512L/no
Publication of NO300267B1 publication Critical patent/NO300267B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/26—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups and being further substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Dry Shavers And Clippers (AREA)
  • Laminated Bodies (AREA)
  • Soft Magnetic Materials (AREA)
  • Paper (AREA)
NO932512A 1991-01-11 1993-07-09 Akridin-derivater, samt anvendelse av slike i farmasöytiske preparater NO300267B1 (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB919100637A GB9100637D0 (en) 1991-01-11 1991-01-11 Chemical compounds
GB919100628A GB9100628D0 (en) 1991-01-11 1991-01-11 Chemical compounds
GB919115981A GB9115981D0 (en) 1991-07-24 1991-07-24 Chemical compounds
GB919115956A GB9115956D0 (en) 1991-07-24 1991-07-24 Chemical compounds
PCT/EP1992/000020 WO1992012132A1 (en) 1991-01-11 1992-01-07 Acridine derivatives

Publications (3)

Publication Number Publication Date
NO932512D0 NO932512D0 (no) 1993-07-09
NO932512L NO932512L (no) 1993-09-09
NO300267B1 true NO300267B1 (no) 1997-05-05

Family

ID=27450605

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932512A NO300267B1 (no) 1991-01-11 1993-07-09 Akridin-derivater, samt anvendelse av slike i farmasöytiske preparater

Country Status (25)

Country Link
US (1) US5604237A (cs)
EP (2) EP0494623A1 (cs)
JP (1) JP2783680B2 (cs)
KR (1) KR100220538B1 (cs)
AT (1) ATE153660T1 (cs)
AU (1) AU652996B2 (cs)
CA (1) CA2100258C (cs)
CZ (1) CZ283038B6 (cs)
DE (1) DE69220037T2 (cs)
DK (1) DK0569380T3 (cs)
ES (1) ES2104887T3 (cs)
FI (1) FI103888B1 (cs)
GE (1) GEP20002210B (cs)
GR (1) GR3024525T3 (cs)
HU (2) HUT68856A (cs)
IE (1) IE920083A1 (cs)
IL (1) IL100631A (cs)
MX (1) MX9200109A (cs)
NO (1) NO300267B1 (cs)
NZ (1) NZ241278A (cs)
PL (1) PL168202B1 (cs)
RU (1) RU2119482C1 (cs)
SG (1) SG45403A1 (cs)
SK (1) SK280864B6 (cs)
WO (1) WO1992012132A1 (cs)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ283038B6 (cs) * 1991-01-11 1997-12-17 Laboratoires Glaxo Sa Akridinové deriváty, způsob výroby a farmaceutické prostředky s jejich obsahem
GB9209872D0 (en) * 1992-05-07 1992-06-24 Ici Plc Alkyl substituted nitrotoluene derivatives
TR28930A (tr) * 1992-05-07 1997-07-21 Zeneca Ltd Alkil sübstitüentli nitrotoluen türevleri
ES2103479T3 (es) * 1992-07-10 1997-09-16 Glaxo Lab Sa Derivados de anilida.
RU2036198C1 (ru) * 1993-04-01 1995-05-27 Товарищество с ограниченной ответственностью "Полисан" N-МЕТИЛ-N-( α,D -ГЛЮКОПИРАНОЗИЛ) АММОНИЯ-2-(АКРИДОН-9-ОН-10-ИЛ)АЦЕТАТ(ЦИКЛОФЕРОН), ОБЛАДАЮЩИЙ ИНТЕРФЕРОНОГЕННОЙ, ПРОТИВОВИРУСНОЙ, В ТОМ ЧИСЛЕ АНТИВИЧ, АНТИПАРАЗИТАРНОЙ, АНТИПРОМОТОРНОЙ И РАДИОПРОТЕКТИВНОЙ АКТИВНОСТЬЮ
US5387685A (en) * 1993-07-16 1995-02-07 American Cyanamid Co MDR reversal agents
DE4422517A1 (de) * 1994-06-28 1996-01-04 Dresden Arzneimittel Neue (2-(3,4-Dimethoxy-phenyl)-ethyl)-(2-phenoxy-ethyl)-amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
CN1134410C (zh) * 1994-08-04 2004-01-14 C&C新药研究所 胺衍生物,制备它们的方法和它们作为抗心律失常药的应用
AU702519B2 (en) * 1994-10-05 1999-02-25 Glaxo Wellcome Inc. Parenteral pharmaceutical compositions containing GF120918A
FR2726267B1 (fr) * 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
US6395770B1 (en) 1995-10-26 2002-05-28 Baker Norton Pharmaceuticals, Inc. Method and compositions for administering taxanes orally to human patients
US6245805B1 (en) 1995-10-26 2001-06-12 Baker Norton Pharmaceuticals, Inc. Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
WO1997028166A1 (de) * 1996-02-01 1997-08-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Thienochinoline
US6713517B1 (en) 1996-03-08 2004-03-30 Oxigene, Inc. Use of aryl N-substituted carboxamides directly and as radio-and chemosensitizers for killing tumor and cancer cells and novel compounds for such use
RU2118532C1 (ru) * 1996-04-10 1998-09-10 Олег Викторович Травкин Противоинфекционное, противовоспалительное и противоопухолевое лекарственное средство
GB2333293B (en) * 1996-10-18 2000-07-12 Xenova Ltd Process for the preparation of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide used as anti cancer compounds
MY118642A (en) * 1996-10-18 2004-12-31 Xenova Ltd Anthranilic acid derivatives as multi drug resistance modulators
GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
GB9710612D0 (en) * 1997-05-23 1997-07-16 Glaxo Group Ltd Synthesis of acridine derivatives
DK0994706T3 (da) * 1997-05-27 2006-03-06 Ivax Research Inc Præparater til oral indgivelse af taxaner og anvendelse deraf
GB9718903D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
GB9812189D0 (en) * 1998-06-05 1998-08-05 Glaxo Group Ltd Methods and compositions for increasing penetration of HIV protease inhibitors
AU4698299A (en) * 1998-06-30 2000-01-17 Du Pont Pharmaceuticals Company 5-HT7 receptor antagonists
RU2135474C1 (ru) * 1998-08-19 1999-08-27 Травкин Олег Викторович Соли 1-дезокси-1-n-метиламиногексаспиртов с n-акридонуксусной кислотой, обладающие иммуномодулирующей активностью, и лекарственное средство на их основе
SK4782001A3 (en) 1998-10-08 2001-11-06 Smithkline Beecham Plc Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
GB9824579D0 (en) * 1998-11-10 1999-01-06 Novartis Ag Organic compounds
EP1749540B1 (en) * 1999-05-17 2010-10-13 Cancer Research Ventures Limited Compositions for improving bioavailability of orally administered drugs
EP2266607A3 (en) 1999-10-01 2011-04-20 Immunogen, Inc. Immunoconjugates for treating cancer
US6521635B1 (en) 2000-01-20 2003-02-18 The United States Of America As Represented By The Department Of Health And Human Services Inhibition of MXR transport by acridine derivatives
AU2001238499A1 (en) 2000-02-18 2001-08-27 New York Medical College Nitroacridine/tumor inhibitor compositions
KR100842698B1 (ko) * 2000-03-14 2008-07-01 액테리온 파마슈티칼 리미티드 1,2,3,4-테트라하이드로이소퀴놀린 유도체
AU779266B2 (en) 2000-05-11 2005-01-13 Banyu Pharmaceutical Co., Ltd. N-acyltetrahydroisoquinoline derivatives
CN1469735A (zh) * 2000-10-16 2004-01-21 ����˹��ҩ�﹫˾ 米托蒽醌的脂质体制剂
KR101060971B1 (ko) * 2002-05-14 2011-09-01 제노바 리미티드 안트라닐산 유도체 수화물의 제조 방법
RU2279873C2 (ru) * 2002-05-31 2006-07-20 Ар.Пи.ШЕРЕР ТЕКНОЛОДЖИЗ, ИНК. Пероральная фармацевтическая композиция для мягких капсул, содержащая винорелбин, и способ лечения
WO2004039795A2 (en) * 2002-10-29 2004-05-13 Fujisawa Pharmaceutical Co., Ltd. Amide compounds for the treatment of hyperlipidemia
DK1751111T3 (en) 2004-03-01 2015-02-09 Actelion Pharmaceuticals Ltd SUBSTITUTED 1,2,3,4-tetrahydroisoquinoline derivatives
RU2326115C2 (ru) * 2005-11-21 2008-06-10 Ефаг АО Соли 1-алкиламино-1-дезоксиполиолов с 9-оксоакридин-10-уксусной кислотой, лекарственные препараты на их основе, применение, способы профилактики и лечения
ES2431564T3 (es) * 2006-03-22 2013-11-27 Janssen Pharmaceutica N.V. Inhibidores de la interacción entre MDM2 y p53
RU2346692C2 (ru) * 2007-03-29 2009-02-20 Ефаг АО Применение 9-оксоакридин-10-уксусной кислоты, ее солей и сложных эфиров в комбинированной терапии рака яичников, способ лечения и наборы
RU2346691C2 (ru) * 2007-03-29 2009-02-20 Ефаг АО Применение 9-оксоакридин-10-уксусной кислоты и/или ее соли в комбинации с антиэстрогеном и/или прогестином для лечения эстрогензависимых опухолей, способ лечения и наборы
SE531698C2 (sv) * 2007-07-12 2009-07-07 Respiratorius Ab Nya bronkdilaterande a,b-omättade amider
WO2015142670A1 (en) * 2014-03-15 2015-09-24 Medisyn Technologies, Inc. Anti-diabetic compounds, pharmaceutical compositions containing them, and method to treat diabetes
CN104434808A (zh) 2014-07-03 2015-03-25 石药集团中奇制药技术（石家庄）有限公司 一种治疗性纳米粒子及其制备方法
CN111867577A (zh) * 2018-03-21 2020-10-30 艾祖米科技有限公司 依克立达的氘化类似物
CN113387873B (zh) * 2021-06-15 2022-09-20 山东第一医科大学(山东省医学科学院) 取代二芳基类化合物其制备方法和用途
CN115252613B (zh) * 2022-08-09 2024-01-12 北京清华长庚医院 药物组合物及其在逆转仑伐替尼耐药性中的用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250182A (en) * 1972-02-24 1981-02-10 Burroughs Wellcome Co. Pharmaceutical composition containing acridone compounds and method of using same
US4021551A (en) * 1972-06-07 1977-05-03 Boehringer Ingelheim Gmbh 3,6-Bis-(heterocyclic aminoacyl-amino)-acridines and salts thereof
US4127573A (en) * 1972-09-06 1978-11-28 Burroughs Wellcome Co. Ditetrazole substituted acridone compounds
DE3170001D1 (en) * 1980-09-30 1985-05-23 Bayer Ag Method for the production of an antithrombin-heparin complex and pharmaceutical compositions containing the complex
NZ198115A (en) * 1981-08-21 1985-05-31 New Zealand Dev Finance 9-anilinoacridines;pharmaceutical compositions
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
IN164921B (cs) * 1986-07-22 1989-07-08 Hoechst India
US5104858A (en) * 1988-09-29 1992-04-14 Yale University Sensitizing multidrug resistant cells to antitumor agents
CA1340821C (en) * 1988-10-06 1999-11-16 Nobuyuki Fukazawa Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components
JPH04506072A (ja) * 1989-06-19 1992-10-22 ザ・ウエルカム・ファウンデーション・リミテッド 癌治療に有用であり、かつ抗ヒスタミン特性を有する医薬
CZ283038B6 (cs) * 1991-01-11 1997-12-17 Laboratoires Glaxo Sa Akridinové deriváty, způsob výroby a farmaceutické prostředky s jejich obsahem
US5296602A (en) * 1991-03-18 1994-03-22 Sloan-Kettering Institute For Cancer Research Multisubstituted 1-hydroxy-9-acridones with anticancer activity
US5240936A (en) * 1992-05-14 1993-08-31 Texas A&M University System Treating or preventing ocular inflammation or systemic imflammatory disease

Also Published As

Publication number Publication date
ATE153660T1 (de) 1997-06-15
NZ241278A (en) 1994-05-26
DE69220037T2 (de) 1997-11-06
KR100220538B1 (ko) 1999-09-15
IE920083A1 (en) 1992-07-15
NO932512L (no) 1993-09-09
DE69220037D1 (de) 1997-07-03
GR3024525T3 (en) 1997-11-28
AU652996B2 (en) 1994-09-15
CA2100258C (en) 1999-12-14
NO932512D0 (no) 1993-07-09
JP2783680B2 (ja) 1998-08-06
IL100631A (en) 1996-09-12
WO1992012132A1 (en) 1992-07-23
IL100631A0 (en) 1992-09-06
PL168202B1 (pl) 1996-01-31
EP0569380B1 (en) 1997-05-28
FI933149A0 (fi) 1993-07-09
CZ283038B6 (cs) 1997-12-17
DK0569380T3 (da) 1997-12-22
CA2100258A1 (en) 1992-07-12
FI933149L (fi) 1993-07-09
GEP20002210B (en) 2000-08-25
SK280864B6 (en) 2000-08-14
SK73093A3 (en) 1994-01-12
MX9200109A (es) 1992-09-01
HUT68856A (en) 1995-08-28
US5604237A (en) 1997-02-18
CZ137893A3 (en) 1994-02-16
JPH06506440A (ja) 1994-07-21
RU2119482C1 (ru) 1998-09-27
EP0569380A1 (en) 1993-11-18
HU211623A9 (en) 1995-12-28
HU9301989D0 (en) 1993-10-28
EP0494623A1 (en) 1992-07-15
AU1154392A (en) 1992-08-17
SG45403A1 (en) 1998-01-16
FI103888B (fi) 1999-10-15
ES2104887T3 (es) 1997-10-16
FI103888B1 (fi) 1999-10-15

Similar Documents

Publication Publication Date Title
NO300267B1 (no) Akridin-derivater, samt anvendelse av slike i farmasöytiske preparater
US5663179A (en) Certain isoquinoline derivatives having anti-tumor properties
NO313591B1 (no) Antranilinsyrederivater som modulatorer av multimedikamentresistens
US5175173A (en) Carboxamides useful as antiemetic or antipsychotic agents
JP2002520317A (ja) ２−アミノピリジン誘導体、その医薬としての使用及びそれを含有する医薬組成物
JP3341019B2 (ja) 選択的ロイコトリエンｂ▲４▼拮抗剤活性を示す置換された単環式アリール化合物
WO1988003137A1 (en) Tetrahydroisoquinolin-2-yl derivatives of carboxylic acids as thromboxane a2 antagonists
KR20140027420A (ko) 헥사히드로디벤조[a,g]퀴나진화합물, 이의 제조방법, 약물조성물 및 그 응용
JPS63277671A (ja) ３−アミノ−ジヒドロ−〔１〕−ベンゾピランおよびベンゾチオピラン
WO2008090434A1 (en) Substituted n-bicyclicalkyl bicyclic carboxyamide compounds
US4515944A (en) 1,5-Diphenyl-2-haloalkylpyrazolin-3-one intermediates
EP0043736B1 (en) Propanolamine derivatives, their salts, processes for preparation and pharmaceutical compositions
JPH08337523A (ja) 血管新生阻害剤
KR20070046878A (ko) 5-ｈｔ7 수용체 안타고니스트
Gan et al. Discovery, stereospecific characterization and peripheral modification of 1-(pyrrolidin-1-ylmethyl)-2-[(6-chloro-3-oxo-indan)-formyl]-1, 2, 3, 4-tetrahydroisoquinolines as novel selective κ opioid receptor agonists
CA1260933A (en) Bicyclic lactams, processes for their preparation and their use, and formulations containing these compounds
CN115160313A (zh) 一种2-苯基咪唑[1,2-a]吡啶类化合物、包含其的组合物及两者的用途
JPH068294B2 (ja) 新規な１，４−ジヒドロピリジン誘導体およびその塩
JPS62103080A (ja) テトラヒドロキノリン誘導体
NO861370L (no) Fremgangsm te for fremstilling av terapeutisk aktivranilin-derivater.
NO853151L (no) Fremgangsmaate for fremstilling av terapeutisk aktive fenetanolamin-derivater.

Legal Events

Date Code Title Description
MK1K Patent expired