NO20084835L - Dyrkingsmetode for a oppna en klonpopulasjon av antigen-spesifikke B celler - Google Patents
Dyrkingsmetode for a oppna en klonpopulasjon av antigen-spesifikke B cellerInfo
- Publication number
- NO20084835L NO20084835L NO20084835A NO20084835A NO20084835L NO 20084835 L NO20084835 L NO 20084835L NO 20084835 A NO20084835 A NO 20084835A NO 20084835 A NO20084835 A NO 20084835A NO 20084835 L NO20084835 L NO 20084835L
- Authority
- NO
- Norway
- Prior art keywords
- antigen
- cells
- obtaining
- specific
- culture method
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 210000003719 b-lymphocyte Anatomy 0.000 title 1
- 238000012136 culture method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80141206P | 2006-05-19 | 2006-05-19 | |
PCT/US2007/011980 WO2008045140A1 (en) | 2006-05-19 | 2007-05-21 | Culture method for obtaining a clonal population of antigen-specific b cells |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20084835L true NO20084835L (no) | 2009-02-16 |
Family
ID=39283142
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20084835A NO20084835L (no) | 2006-05-19 | 2008-11-18 | Dyrkingsmetode for a oppna en klonpopulasjon av antigen-spesifikke B celler |
Country Status (12)
Country | Link |
---|---|
US (3) | US20070269868A1 (zh) |
EP (1) | EP2021463B1 (zh) |
JP (1) | JP5607357B2 (zh) |
CN (1) | CN101600793B (zh) |
AU (1) | AU2007307324B2 (zh) |
CA (1) | CA2652392C (zh) |
DK (1) | DK2021463T3 (zh) |
IL (1) | IL195285A (zh) |
MX (1) | MX2008014692A (zh) |
NO (1) | NO20084835L (zh) |
NZ (1) | NZ572807A (zh) |
WO (1) | WO2008045140A1 (zh) |
Families Citing this family (66)
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US7906117B2 (en) | 2007-05-21 | 2011-03-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever |
US8062864B2 (en) | 2007-05-21 | 2011-11-22 | Alderbio Holdings Llc | Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies |
US8178101B2 (en) | 2007-05-21 | 2012-05-15 | Alderbio Holdings Inc. | Use of anti-IL-6 antibodies having specific binding properties to treat cachexia |
EP3187506B1 (en) | 2007-05-21 | 2019-03-27 | AlderBio Holdings LLC | Antibodies to il-6 and use thereof |
US8404235B2 (en) | 2007-05-21 | 2013-03-26 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
US8252286B2 (en) | 2007-05-21 | 2012-08-28 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
US9701747B2 (en) | 2007-05-21 | 2017-07-11 | Alderbio Holdings Llc | Method of improving patient survivability and quality of life by anti-IL-6 antibody administration |
US8323649B2 (en) | 2008-11-25 | 2012-12-04 | Alderbio Holdings Llc | Antibodies to IL-6 and use thereof |
US8992920B2 (en) | 2008-11-25 | 2015-03-31 | Alderbio Holdings Llc | Anti-IL-6 antibodies for the treatment of arthritis |
US8337847B2 (en) | 2008-11-25 | 2012-12-25 | Alderbio Holdings Llc | Methods of treating anemia using anti-IL-6 antibodies |
US9212223B2 (en) | 2008-11-25 | 2015-12-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
US9452227B2 (en) | 2008-11-25 | 2016-09-27 | Alderbio Holdings Llc | Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments |
JP5832292B2 (ja) * | 2008-11-25 | 2015-12-16 | アルダーバイオ ホールディングス エルエルシー | 悪液質、虚弱、疲労、および/または発熱を予防または治療するためのil−6のアンタゴニスト |
US8420089B2 (en) | 2008-11-25 | 2013-04-16 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
US9079942B2 (en) * | 2009-02-09 | 2015-07-14 | Epitomics, Inc. | CDR-anchored amplification method |
US20100317539A1 (en) * | 2009-06-12 | 2010-12-16 | Guo-Liang Yu | Library of Engineered-Antibody Producing Cells |
CA2772613C (en) | 2009-09-03 | 2020-03-10 | Schering Corporation | Anti-gitr antibodies |
US8293483B2 (en) | 2009-09-11 | 2012-10-23 | Epitomics, Inc. | Method for identifying lineage-related antibodies |
US9468676B2 (en) | 2009-11-24 | 2016-10-18 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
US9775921B2 (en) | 2009-11-24 | 2017-10-03 | Alderbio Holdings Llc | Subcutaneously administrable composition containing anti-IL-6 antibody |
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PL2400298T3 (pl) * | 2010-05-28 | 2014-01-31 | Hoffmann La Roche | Sposób hodowania pojedynczych komórek b oraz wytwarzania swoistych przeciwciał |
US8992908B2 (en) | 2010-11-23 | 2015-03-31 | Alderbio Holdings Llc | Anti-IL-6 antibodies for the treatment of oral mucositis |
MX359070B (es) | 2010-12-01 | 2018-09-13 | Alderbio Holdings Llc | Composiciones anti-ngf y uso de las mismas. |
US9487583B2 (en) | 2011-03-30 | 2016-11-08 | National University Corporation University Of Toyama | Method for selecting plasma cells or plasmablasts, method for producing target antigen specific antibodies, and novel monoclonal antibodies |
AR086516A1 (es) | 2011-05-20 | 2013-12-18 | Alderbio Holdings Llc | Composiciones anti-peptido relacionado con el gen de la calcitonina y su uso |
CA2836800A1 (en) | 2011-05-20 | 2012-11-29 | Alderbio Holdings Llc | Use of anti-cgrp antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers |
CN103957935B (zh) | 2011-05-20 | 2018-04-03 | 奥尔德生物控股有限责任公司 | 抗cgrp或抗cgrp‑r抗体或抗体片段用于治疗或预防慢性和急性形式的腹泻的用途 |
JP2014518080A (ja) * | 2011-06-27 | 2014-07-28 | バルネバ | 細胞のスクリーニング方法 |
US11782053B2 (en) * | 2011-09-28 | 2023-10-10 | iRepertoire, Inc. | Identification of antigen-specific adaptive immune responses using ARM-PCR and high-throughput sequencing |
MX2014005479A (es) | 2011-11-23 | 2014-08-18 | Hoffmann La Roche | Celulas de mamifero que expresan cd40l y su uso. |
KR20140104963A (ko) | 2011-12-21 | 2014-08-29 | 에프. 호프만-라 로슈 아게 | 동족 항체 가변 영역 유전자 분절의 클로닝 및 발현을 위한 신속법 |
EP2727941A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Method for the production of multispecific antibodies |
EP2727943A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Trispecific antibodies against human EGFR, HER2 and HER3 |
WO2014067642A1 (en) | 2012-11-05 | 2014-05-08 | Mab Discovery Gmbh | Method for the production of multispecific antibodies |
EP2727942A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Bispecific antibodies against human EGFR, HER2, and HER3 |
JP6480338B2 (ja) | 2012-11-08 | 2019-03-06 | セセン バイオ, インコーポレイテッド | Il−6アンタゴニストおよびその使用 |
AU2013344992A1 (en) * | 2012-11-13 | 2015-05-14 | Genentech, Inc. | Enrichment of antigen-specific plasmablasts |
WO2014124677A1 (en) * | 2013-02-15 | 2014-08-21 | Esbatech - A Novartis Company Llc | Acceptor framework for cdr grafting |
CN105246915A (zh) * | 2013-03-14 | 2016-01-13 | 奥尔德生物制药公司 | Hgf抗体及含有其的组合物 |
US9518082B2 (en) | 2013-03-15 | 2016-12-13 | Alderbio Holdings Llc | Antibody purification and purity monitoring |
KR102202477B1 (ko) | 2013-03-15 | 2021-01-13 | 룬드벡 시애틀 바이오파마슈티컬즈, 인크. | 효모 및 기타 형질전환 세포에서 폴리펩티드의 고수율 발현을 위한 온도 전환 |
KR20150140679A (ko) * | 2013-03-15 | 2015-12-16 | 앨더 바이오파마슈티컬즈, 인코포레이티드 | 항원-특이적 b 세포를 확인하고 단리시키고, 원하는 항원에 대한 항체를 생성하기 위한 프로토콜 |
US20160075766A1 (en) | 2013-05-21 | 2016-03-17 | Roche Diagnostics Operations, Inc. | Method for producing antibodies using ovine b-cells and uses thereof |
CN104232577B (zh) * | 2013-06-20 | 2017-12-01 | 中国人民解放军军事医学科学院基础医学研究所 | 一种获得自身反应性b细胞的方法 |
CA2916980C (en) | 2013-07-03 | 2023-02-21 | Alder Biopharmaceuticals, Inc. | Regulation of glucose metabolism using anti-cgrp antibodies |
MY185114A (en) | 2014-11-07 | 2021-04-30 | Sesen Bio Inc | Improved il-6 antibodies |
EP3271393A4 (en) * | 2015-03-18 | 2018-10-31 | Epitomics, Inc. | High throughput monoclonal antibody generation by b cell panning and proliferation |
JP7128460B2 (ja) | 2015-06-04 | 2022-08-31 | 国立研究開発法人国立精神・神経医療研究センター | Il-6阻害剤を有効成分とする精神疾患治療剤 |
CN108026172B (zh) | 2015-06-26 | 2022-04-29 | 赛诺菲生物技术公司 | 单克隆抗il-1racp抗体 |
AU2017223687A1 (en) | 2016-02-23 | 2018-08-09 | Sesen Bio, Inc. | IL-6 antagonist formulations and uses thereof |
WO2017167714A1 (en) | 2016-03-30 | 2017-10-05 | F. Hoffmann-La Roche Ag | B-cell cultivation method |
EP3426686A4 (en) | 2016-04-15 | 2019-11-06 | Alder Biopharmaceuticals, Inc. | HUMANIZED ANTI-PACAP ANTIBODIES AND USES THEREOF |
EP3241845A1 (en) | 2016-05-06 | 2017-11-08 | MAB Discovery GmbH | Humanized anti-il-1r3 antibodies |
CN106350485B (zh) * | 2016-08-24 | 2020-02-21 | 杭州百凌生物科技有限公司 | 一种快速高效分离单个抗原特异性b细胞的方法 |
JP6916884B2 (ja) | 2017-01-02 | 2021-08-11 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | B細胞培養法 |
EP3401332A1 (en) | 2017-05-08 | 2018-11-14 | MAB Discovery GmbH | Anti-il-1r3 antibodies for use in inflammatory conditions |
WO2018210896A1 (en) | 2017-05-19 | 2018-11-22 | F. Hoffmann-La Roche Ag | Method for the production of thymocyte supernatant |
US11125757B2 (en) * | 2017-05-26 | 2021-09-21 | Emory University | Methods of culturing and characterizing antibody secreting cells |
WO2019105864A1 (en) | 2017-11-30 | 2019-06-06 | F. Hoffmann-La Roche Ag | B-cell cultivation method |
US20210246195A1 (en) * | 2018-05-18 | 2021-08-12 | Chan Zuckerberg Biohub, Inc. | Methods of isolating allergen-specific antibodies from humans and uses thereof |
US20220306734A1 (en) | 2019-07-24 | 2022-09-29 | H. Lundbeck A/S | Anti-mglur5 antibodies and uses thereof |
JP2023106635A (ja) | 2020-04-17 | 2023-08-02 | 中外製薬株式会社 | 二重特異性抗原結合分子ならびに、それに関連する組成物、組成物の製造のための使用、キット、および方法 |
WO2022004620A1 (ja) * | 2020-06-29 | 2022-01-06 | 株式会社Npt | 抗原特異的抗体産生細胞を含む組成物の製造方法、ワクチン組成物の製造方法、細胞分離キットおよびワクチン組成物 |
US20240228595A1 (en) * | 2021-05-11 | 2024-07-11 | Yale University | Methods for Monoclonal Antibody Generation |
WO2024062074A1 (en) | 2022-09-21 | 2024-03-28 | Sanofi Biotechnology | Humanized anti-il-1r3 antibody and methods of use |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6657103B1 (en) * | 1990-01-12 | 2003-12-02 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
WO1991017177A1 (en) * | 1990-05-04 | 1991-11-14 | Baxter Diagnostics Inc. | High affinity antibodies to small peptides |
CA2090126C (en) | 1990-08-02 | 2002-10-22 | John W. Schrader | Methods for the production of proteins with a desired function |
DE69126281T2 (de) * | 1990-11-26 | 1997-10-16 | Akzo Nobel Nv | Verfahren zur Herstellung von Antikörpern |
US6277969B1 (en) * | 1991-03-18 | 2001-08-21 | New York University | Anti-TNF antibodies and peptides of human tumor necrosis factor |
US5256542A (en) * | 1992-03-09 | 1993-10-26 | Tanox Biosystems, Inc. | Selecting low frequency antigen-specific single B lymphocytes with correction for background noise |
US6972125B2 (en) * | 1999-02-12 | 2005-12-06 | Genetics Institute, Llc | Humanized immunoglobulin reactive with B7-2 and methods of treatment therewith |
ES2624547T3 (es) * | 2001-11-14 | 2017-07-14 | Janssen Biotech, Inc. | Anticuerpos anti il 6, composiciones, métodos y usos |
US20040185040A1 (en) * | 2001-11-21 | 2004-09-23 | Celltech R & D Limited | Modulating immune responses |
US8188231B2 (en) * | 2002-09-27 | 2012-05-29 | Xencor, Inc. | Optimized FC variants |
JP4603894B2 (ja) | 2002-12-03 | 2010-12-22 | ユセベ ファルマ ソシエテ アノニム | 抗体産生細胞を同定するためのアッセイ |
GB0312481D0 (en) | 2003-05-30 | 2003-07-09 | Celltech R&D Ltd | Antibodies |
EP1651659A4 (en) * | 2003-08-07 | 2008-09-17 | Epitomics Inc | METHOD FOR HUMANIZATION OF MONOCLONAL RABBIT ANTIBODIES |
WO2005019823A1 (en) | 2003-08-20 | 2005-03-03 | Celltech R & D Limited | Methods for obtaining antibodies |
ES2385829T3 (es) | 2003-08-20 | 2012-08-01 | Ucb Pharma, S.A. | Métodos para obtener anticuerpos |
AU2004266159A1 (en) * | 2003-08-22 | 2005-03-03 | Biogen Idec Ma Inc. | Improved antibodies having altered effector function and methods for making the same |
CA2536675A1 (en) * | 2003-08-29 | 2005-03-10 | Centocor, Inc. | A rapid way to obtain high expression clones of mammalian cells using a methylcellulose and immunoprecipitation screening method |
ES2630224T3 (es) * | 2003-10-22 | 2017-08-18 | Keck Graduate Institute | Métodos para sintetizar polipéptidos heteromultiméricos en levadura con el uso de una estrategia de apareamiento haploide |
GB0412973D0 (en) | 2004-06-10 | 2004-07-14 | Celltech R&D Ltd | Identification of antibody producing cells |
US20060051348A1 (en) * | 2004-09-09 | 2006-03-09 | Jorn Gorlach | Method of producing a plurality of isolated antibodies to a plurality of cognate antigens |
EP1799717B1 (en) * | 2004-10-22 | 2015-05-20 | Danisco US Inc. | Isolating human antibodies |
US7462697B2 (en) * | 2004-11-08 | 2008-12-09 | Epitomics, Inc. | Methods for antibody engineering |
GB0425972D0 (en) | 2004-11-25 | 2004-12-29 | Celltech R&D Ltd | Biological products |
PA8672101A1 (es) * | 2005-04-29 | 2006-12-07 | Centocor Inc | Anticuerpos anti-il-6, composiciones, métodos y usos |
US20070092943A1 (en) * | 2005-09-28 | 2007-04-26 | The University Of Chicago | Versatile vectors for expression of foreign proteins in photosynthetic bacteria |
-
2007
- 2007-05-21 WO PCT/US2007/011980 patent/WO2008045140A1/en active Application Filing
- 2007-05-21 AU AU2007307324A patent/AU2007307324B2/en not_active Ceased
- 2007-05-21 JP JP2009512060A patent/JP5607357B2/ja not_active Expired - Fee Related
- 2007-05-21 EP EP07861311.4A patent/EP2021463B1/en not_active Revoked
- 2007-05-21 MX MX2008014692A patent/MX2008014692A/es active IP Right Grant
- 2007-05-21 CA CA2652392A patent/CA2652392C/en not_active Expired - Fee Related
- 2007-05-21 NZ NZ572807A patent/NZ572807A/en not_active IP Right Cessation
- 2007-05-21 US US11/802,235 patent/US20070269868A1/en not_active Abandoned
- 2007-05-21 CN CN200780027028.2A patent/CN101600793B/zh not_active Expired - Fee Related
- 2007-05-21 DK DK07861311.4T patent/DK2021463T3/en active
-
2008
- 2008-11-13 IL IL195285A patent/IL195285A/en active IP Right Grant
- 2008-11-18 NO NO20084835A patent/NO20084835L/no unknown
-
2011
- 2011-08-08 US US13/204,915 patent/US20120141982A1/en not_active Abandoned
-
2013
- 2013-04-12 US US13/861,518 patent/US20130316353A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2009537176A (ja) | 2009-10-29 |
US20070269868A1 (en) | 2007-11-22 |
MX2008014692A (es) | 2009-08-18 |
CA2652392C (en) | 2017-10-10 |
AU2007307324B2 (en) | 2013-08-15 |
US20120141982A1 (en) | 2012-06-07 |
CN101600793B (zh) | 2013-06-26 |
US20130316353A1 (en) | 2013-11-28 |
WO2008045140A1 (en) | 2008-04-17 |
EP2021463B1 (en) | 2016-11-23 |
NZ572807A (en) | 2011-10-28 |
EP2021463A4 (en) | 2009-09-02 |
IL195285A (en) | 2012-07-31 |
AU2007307324A1 (en) | 2008-04-17 |
DK2021463T3 (en) | 2017-01-16 |
EP2021463A1 (en) | 2009-02-11 |
JP5607357B2 (ja) | 2014-10-15 |
CA2652392A1 (en) | 2008-04-17 |
CN101600793A (zh) | 2009-12-09 |
IL195285A0 (en) | 2011-08-01 |
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