NO20084539L - Humaniserte monoklonale antistoffer til hepatocyttvekstfaktor - Google Patents
Humaniserte monoklonale antistoffer til hepatocyttvekstfaktorInfo
- Publication number
- NO20084539L NO20084539L NO20084539A NO20084539A NO20084539L NO 20084539 L NO20084539 L NO 20084539L NO 20084539 A NO20084539 A NO 20084539A NO 20084539 A NO20084539 A NO 20084539A NO 20084539 L NO20084539 L NO 20084539L
- Authority
- NO
- Norway
- Prior art keywords
- growth factor
- hepatocyte growth
- monoclonal antibodies
- humanized monoclonal
- composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78824306P | 2006-04-01 | 2006-04-01 | |
PCT/US2007/065385 WO2007115049A2 (en) | 2006-04-01 | 2007-03-28 | Humanized monoclonal antibodies to hepatocyte growth factor |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20084539L true NO20084539L (no) | 2008-10-28 |
Family
ID=38564195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20084539A NO20084539L (no) | 2006-04-01 | 2008-10-28 | Humaniserte monoklonale antistoffer til hepatocyttvekstfaktor |
Country Status (26)
Country | Link |
---|---|
US (3) | US7632926B2 (es) |
EP (2) | EP2016162B1 (es) |
JP (1) | JP5312315B2 (es) |
KR (1) | KR101516289B1 (es) |
CN (2) | CN103172736A (es) |
AR (1) | AR059922A1 (es) |
AU (1) | AU2007233242B2 (es) |
BR (1) | BRPI0709932A2 (es) |
CA (1) | CA2645358C (es) |
CO (1) | CO6140067A2 (es) |
CR (1) | CR10308A (es) |
ES (1) | ES2465668T3 (es) |
GE (1) | GEP20125517B (es) |
HK (1) | HK1121489A1 (es) |
IL (1) | IL194221A (es) |
MA (1) | MA30382B1 (es) |
MX (1) | MX2008012619A (es) |
MY (1) | MY145042A (es) |
NO (1) | NO20084539L (es) |
NZ (1) | NZ571132A (es) |
PE (1) | PE20080008A1 (es) |
RU (1) | RU2461570C2 (es) |
TW (1) | TWI417300B (es) |
UA (1) | UA94452C2 (es) |
WO (1) | WO2007115049A2 (es) |
ZA (1) | ZA200807903B (es) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
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US20040208876A1 (en) * | 2003-04-18 | 2004-10-21 | Kim Kyung Jin | Monoclonal antibodies to hepatocyte growth factor |
MXPA06000508A (es) | 2003-07-18 | 2006-04-05 | Amgen Inc | Agentes de union especifica al factor del crecimiento de los hepatocitos. |
CA2607699A1 (en) * | 2005-06-02 | 2006-12-07 | Galaxy Biotech, Llc | Methods of treating brain tumors with antibodies |
AR059922A1 (es) | 2006-04-01 | 2008-05-07 | Galaxy Biotech Llc | Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos |
ATE495195T1 (de) | 2006-06-02 | 2011-01-15 | Aveo Pharmaceuticals Inc | Hepatocytenwachstumsfaktor-(hgf-)bindungsprotei e |
BRPI0712223A2 (pt) | 2006-06-02 | 2012-07-10 | Aveo Pharmaceuticals Inc | proteìnas de ligação ao fator de crescimento de hepatócito (hgf) |
PL2032166T3 (pl) | 2006-06-13 | 2013-09-30 | Oncomed Pharm Inc | Kompozycje i sposoby diagnozowania i leczenia nowotworów |
JP5618544B2 (ja) | 2007-01-24 | 2014-11-05 | オンコメッドファーマシューティカルズ インコーポレイテッド | 癌の診断および処置のための組成物および方法 |
TW200940064A (en) * | 2008-03-06 | 2009-10-01 | Genentech Inc | Combination therapy with C-MET and EGFR antagonists |
EP2274153B1 (en) * | 2008-04-10 | 2012-07-04 | Objet Ltd. | System and method for three dimensional model printing |
TW201002346A (en) * | 2008-04-11 | 2010-01-16 | Galaxy Biotech Llc | Combination of HGF inhibitor and EGF inhibitor to treat cancer |
PE20091714A1 (es) * | 2008-04-11 | 2009-11-15 | Galaxy Biotech Llc | Combinacion del inhibidor hgf y el agonista pten |
US20110217294A1 (en) * | 2008-04-11 | 2011-09-08 | Daniel Fults | Combination of hgf inhibitor and hedgehog inhibitor to treat cancer |
WO2009140549A1 (en) * | 2008-05-14 | 2009-11-19 | Amgen Inc. | Combinations vegf(r) inhibitors and hepatocyte growth factor (c-met) inhibitors for the treatment of cancer |
US8101725B2 (en) | 2008-05-29 | 2012-01-24 | Galaxy Biotech, Llc | Monoclonal antibodies to basic fibroblast growth factor |
AU2009269095B2 (en) | 2008-07-08 | 2016-05-19 | Oncomed Pharmaceuticals, Inc. | Notch-binding agents and antagonists and methods of use thereof |
US9132189B2 (en) | 2008-07-08 | 2015-09-15 | Oncomed Pharmaceuticals, Inc. | Notch1 binding agents and methods of use thereof |
BRPI0917315B8 (pt) | 2008-11-07 | 2021-05-25 | Galaxy Biotech Llc | anticorpo monoclonal, seu uso e composição farmacêutica o compreendendo |
EP2360183B1 (en) | 2008-12-19 | 2016-07-27 | Takeda Pharmaceutical Company Limited | Antibody purification method by mixed mode chromatography utilizing an arginine-containing loading solution |
WO2010119991A2 (en) | 2009-04-17 | 2010-10-21 | Takeda Pharmaceutical Company Limited | Novel method of treating cancer |
WO2010136482A1 (en) * | 2009-05-28 | 2010-12-02 | Glaxo Group Limited | Antigen-binding proteins |
EP2523682B1 (en) | 2010-01-13 | 2015-12-16 | Oncomed Pharmaceuticals, Inc. | Notch1 binding agents and methods of use thereof |
EP3904391B1 (en) | 2010-03-10 | 2024-07-10 | Genmab A/S | Monoclonal antibodies against c-met |
JP2013532627A (ja) | 2010-07-01 | 2013-08-19 | 武田薬品工業株式会社 | cMET阻害剤とHGFおよび/またはcMETに対する抗体との組み合わせ |
JP2013537918A (ja) | 2010-09-27 | 2013-10-07 | エクセリクシス, インク. | 去勢抵抗性前立腺癌および骨芽細胞骨転移の治療のためのmetおよびvegfの二元阻害薬 |
SG190362A1 (en) * | 2010-11-24 | 2013-06-28 | Glaxo Group Ltd | Multispecific antigen binding proteins targeting hgf |
KR20140067052A (ko) | 2011-09-09 | 2014-06-03 | 암젠 인코퍼레이티드 | 식도암 및 위암 환자들에서 항-간세포 성장 인자(“hgf”) 항체들의 유효성을 예측하기 위한 c―met 단백질의 용도 |
WO2013152252A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
EP2873422A4 (en) | 2012-07-10 | 2015-12-30 | Takeda Pharmaceutical | PHARMACEUTICAL PREPARATION FOR INJECTION |
US9931400B2 (en) | 2012-09-12 | 2018-04-03 | Samsung Electronics Co., Ltd. | Method of combination therapy for prevention or treatment of c-Met or angiogenesis factor induced diseases |
US9732150B2 (en) | 2013-03-14 | 2017-08-15 | Alderbio Holdings Llc | Therapeutic use of antibodies to HGF |
US9062104B2 (en) | 2013-03-14 | 2015-06-23 | Alderbio Holdings Llc | Therapeutic use of antibodies to HGF |
JP2016516052A (ja) * | 2013-03-14 | 2016-06-02 | アルダー・バイオファーマシューティカルズ・インコーポレーテッド | Hgfに対する抗体及びそれらを含む組成物 |
MA39776A (fr) | 2014-03-24 | 2017-02-01 | Hoffmann La Roche | Traitement du cancer avec des antagonistes de c-met et corrélation de ces derniers avec l'expression de hgf |
CA3003033A1 (en) | 2015-10-30 | 2017-05-04 | Galaxy Biotech, Llc | Highly potent antibodies binding to death receptor 4 and death receptor 5 |
RU2756275C2 (ru) | 2016-03-01 | 2021-09-29 | Юссум Рисёрч Девелопмент Компани Оф Зэ Хибру Юниверсити Оф Иерусалим Лтд. | Антитела, специфические к рецептору полиовируса (pvr) человека |
US20220275368A1 (en) | 2019-08-12 | 2022-09-01 | Interna Technologies B.V. | New treatments involving mirna-193a |
CN115461461A (zh) | 2020-02-28 | 2022-12-09 | 因特尔纳技术有限公司 | 用于促进免疫原性细胞死亡的miRNA-193a |
CN113980129B (zh) * | 2021-01-15 | 2023-07-28 | 东大生物技术(苏州)有限公司 | 一组il-11单克隆抗体及其医药用途 |
Family Cites Families (38)
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JP2564486B2 (ja) * | 1986-07-14 | 1996-12-18 | 修治 橋本 | 肝細胞増殖因子 |
AU600575B2 (en) | 1987-03-18 | 1990-08-16 | Sb2, Inc. | Altered antibodies |
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EP0746609A4 (en) | 1991-12-17 | 1997-12-17 | Genpharm Int | NON-HUMAN TRANSGENIC ANIMALS CAPABLE OF PRODUCING HETEROLOGOUS ANTIBODIES |
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AU1598801A (en) * | 1999-11-09 | 2001-06-06 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | HGF-SF monoclonal antibody combinations |
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JP2005527488A (ja) | 2001-12-27 | 2005-09-15 | バン アンデル リサーチ インスティチュート | Metを発現し、肝細胞増殖因子と結合する腫瘍のモノクローナル抗体画像化および治療 |
WO2004019991A2 (en) * | 2002-08-30 | 2004-03-11 | F. Hoffmann-La Roche Ag | Scatter factor/hepatocyte growth factor antagonist nk4 for the treatment of glioma |
AU2003900180A0 (en) * | 2003-01-16 | 2003-01-30 | Silverbrook Research Pty Ltd | Method and apparatus (dam001) |
US7220410B2 (en) | 2003-04-18 | 2007-05-22 | Galaxy Biotech, Llc | Monoclonal antibodies to hepatocyte growth factor |
US20040208876A1 (en) * | 2003-04-18 | 2004-10-21 | Kim Kyung Jin | Monoclonal antibodies to hepatocyte growth factor |
SI1636593T1 (sl) | 2003-06-06 | 2009-08-31 | Genentech Inc | Moduliranje interakcije med beta-verigo HGF in c-met |
DE602004024536D1 (de) | 2003-07-07 | 2010-01-21 | Van Andel Res Inst | Hemmung der tumor-angiogenese durch eine kombination von thrombospondin-1 und hemmern des vaskulären endothel-wachstumsfaktors |
MXPA06000508A (es) | 2003-07-18 | 2006-04-05 | Amgen Inc | Agentes de union especifica al factor del crecimiento de los hepatocitos. |
US20070030790A1 (en) | 2003-09-18 | 2007-02-08 | Koninklijke Philips Electronics N.V. | Information carrier and system for reading data stored on such an information carrier |
ES2651730T3 (es) * | 2003-09-26 | 2018-01-29 | Exelixis, Inc. | Moduladores c-Met y métodos de uso |
KR100556660B1 (ko) * | 2003-11-11 | 2006-03-10 | 국립암센터 | Hgf의 중화가능 에피토프 및 이에 결합하는 중화 항체 |
WO2005079489A2 (en) * | 2004-02-17 | 2005-09-01 | Science & Technology Corporation @ Unm | Method of treating cancer and identifying novel anti-ancer compounds |
JP5368701B2 (ja) * | 2004-07-02 | 2013-12-18 | エクセリクシス、インコーポレイテッド | c−Metモジュレーター及び使用方法 |
CA2607699A1 (en) * | 2005-06-02 | 2006-12-07 | Galaxy Biotech, Llc | Methods of treating brain tumors with antibodies |
US7964365B2 (en) * | 2005-11-08 | 2011-06-21 | The United States of Americam as represented by the Secretary, Department of Health and Human Services | Methods for diagnosing and monitoring the progression of cancer |
AR059922A1 (es) * | 2006-04-01 | 2008-05-07 | Galaxy Biotech Llc | Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos |
-
2007
- 2007-03-16 AR ARP070101084A patent/AR059922A1/es not_active Application Discontinuation
- 2007-03-26 PE PE2007000342A patent/PE20080008A1/es not_active Application Discontinuation
- 2007-03-28 NZ NZ571132A patent/NZ571132A/en not_active IP Right Cessation
- 2007-03-28 CN CN2012105645795A patent/CN103172736A/zh active Pending
- 2007-03-28 GE GEAP200710944A patent/GEP20125517B/en unknown
- 2007-03-28 BR BRPI0709932-0A patent/BRPI0709932A2/pt not_active IP Right Cessation
- 2007-03-28 KR KR1020087026853A patent/KR101516289B1/ko not_active IP Right Cessation
- 2007-03-28 UA UAA200812789A patent/UA94452C2/ru unknown
- 2007-03-28 ZA ZA200807903A patent/ZA200807903B/xx unknown
- 2007-03-28 CA CA2645358A patent/CA2645358C/en not_active Expired - Fee Related
- 2007-03-28 ES ES07759598.1T patent/ES2465668T3/es active Active
- 2007-03-28 JP JP2009503254A patent/JP5312315B2/ja not_active Expired - Fee Related
- 2007-03-28 EP EP07759598.1A patent/EP2016162B1/en active Active
- 2007-03-28 CN CN2007800123673A patent/CN101415811B/zh not_active Expired - Fee Related
- 2007-03-28 WO PCT/US2007/065385 patent/WO2007115049A2/en active Application Filing
- 2007-03-28 EP EP11192887A patent/EP2476704A3/en not_active Withdrawn
- 2007-03-28 MX MX2008012619A patent/MX2008012619A/es active IP Right Grant
- 2007-03-28 AU AU2007233242A patent/AU2007233242B2/en not_active Ceased
- 2007-03-28 RU RU2008143318/10A patent/RU2461570C2/ru not_active IP Right Cessation
- 2007-03-29 US US11/731,774 patent/US7632926B2/en not_active Expired - Fee Related
- 2007-03-30 TW TW096111376A patent/TWI417300B/zh not_active IP Right Cessation
-
2008
- 2008-09-18 MY MYPI20083653A patent/MY145042A/en unknown
- 2008-09-21 IL IL194221A patent/IL194221A/en not_active IP Right Cessation
- 2008-09-22 CR CR10308A patent/CR10308A/es not_active Application Discontinuation
- 2008-10-17 MA MA31306A patent/MA30382B1/fr unknown
- 2008-10-28 NO NO20084539A patent/NO20084539L/no not_active Application Discontinuation
- 2008-10-28 CO CO08115094A patent/CO6140067A2/es unknown
-
2009
- 2009-02-27 HK HK09101921.3A patent/HK1121489A1/xx not_active IP Right Cessation
- 2009-09-29 US US12/569,463 patent/US8628778B2/en not_active Expired - Fee Related
-
2014
- 2014-01-08 US US14/150,674 patent/US20140335076A1/en not_active Abandoned
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