NO20074102L - Rensing av Rapamycin - Google Patents

Rensing av Rapamycin

Info

Publication number
NO20074102L
NO20074102L NO20074102A NO20074102A NO20074102L NO 20074102 L NO20074102 L NO 20074102L NO 20074102 A NO20074102 A NO 20074102A NO 20074102 A NO20074102 A NO 20074102A NO 20074102 L NO20074102 L NO 20074102L
Authority
NO
Norway
Prior art keywords
rapamycin
purification
purified rapamycin
chemical process
obtaining
Prior art date
Application number
NO20074102A
Other languages
English (en)
Norwegian (no)
Inventor
Bogdan Kazimierz Wilk
Warren Chew
Chia-Cheng Shaw
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20074102L publication Critical patent/NO20074102L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20074102A 2005-03-02 2007-08-08 Rensing av Rapamycin NO20074102L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65791005P 2005-03-02 2005-03-02
PCT/US2006/006212 WO2006093745A1 (en) 2005-03-02 2006-02-22 Purification of rapamycin

Publications (1)

Publication Number Publication Date
NO20074102L true NO20074102L (no) 2007-09-26

Family

ID=36568679

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074102A NO20074102L (no) 2005-03-02 2007-08-08 Rensing av Rapamycin

Country Status (15)

Country Link
US (1) US7384953B2 (ko)
EP (1) EP1853612A1 (ko)
JP (1) JP2008531686A (ko)
KR (1) KR20070107087A (ko)
CN (1) CN101133065A (ko)
AU (1) AU2006218918A1 (ko)
CA (1) CA2599582A1 (ko)
CR (1) CR9297A (ko)
IL (1) IL185077A0 (ko)
MX (1) MX2007010716A (ko)
NI (1) NI200700225A (ko)
NO (1) NO20074102L (ko)
RU (1) RU2007130406A (ko)
WO (1) WO2006093745A1 (ko)
ZA (1) ZA200707523B (ko)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2344821C2 (ru) * 2002-07-30 2009-01-27 Уайт Парентеральные композиции, содержащие гидроксиэфиры рапамицина
JP2010509317A (ja) * 2006-11-10 2010-03-25 バイオコン リミテッド 純粋な形態のラパマイシンならびにこの回収方法および精製方法
US8414526B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
US9700704B2 (en) 2006-11-20 2017-07-11 Lutonix, Inc. Drug releasing coatings for balloon catheters
US20080276935A1 (en) 2006-11-20 2008-11-13 Lixiao Wang Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US9737640B2 (en) 2006-11-20 2017-08-22 Lutonix, Inc. Drug releasing coatings for medical devices
US8414525B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8998846B2 (en) 2006-11-20 2015-04-07 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8414910B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US20080175887A1 (en) 2006-11-20 2008-07-24 Lixiao Wang Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
US8425459B2 (en) 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
WO2010024898A2 (en) 2008-08-29 2010-03-04 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
JP2012533548A (ja) 2009-07-14 2012-12-27 バイオジェン・アイデック・エムエイ・インコーポレイテッド 組成物における黄色形成および過酸化物形成を阻害する方法
CN102443012B (zh) * 2010-10-13 2016-03-02 鲁南制药集团股份有限公司 一种从发酵液中提纯雷帕霉素的方法
US9750728B2 (en) 2012-09-29 2017-09-05 Targeted Therapeutics, Llc Method and pharmaceutical composition for inhibiting PI3K/AKT/mTOR signaling pathway
CN103705925B (zh) 2012-09-29 2018-03-30 段磊 抑制PI3K/AKT/mTOR信号通路的药物组合
ES2897473T3 (es) 2013-03-15 2022-03-01 Biosensors Int Group Ltd Purificación de derivados de la rapamicina
AU2014332080B2 (en) 2013-10-08 2020-02-27 AI Therapeutics, Inc. Rapamycin for the treatment of lymphangioleiomyomatosis
FI3125875T3 (fi) * 2014-04-04 2023-08-24 Ai Therapeutics Inc Inhaloitava rapamysiiniformulaatio ikäsidonnaisten tilojen hoitoon
EP3209330B1 (en) 2014-10-07 2022-02-23 AI Therapeutics, Inc. An inhalable sirolimus formulation for the treatment of pulmonary hypertension
WO2016130645A1 (en) 2015-02-10 2016-08-18 Lam Therapeutics, Inc. Rapamycin for the treatment of lymphangioleiomyomatosis
WO2018031789A1 (en) 2016-08-10 2018-02-15 The Board Of Regents Of The University Of Texas System Topical rapamycin therapy
CN109369679A (zh) * 2018-12-24 2019-02-22 江苏卓和药业有限公司 一种雷帕霉素的精制方法
CN109369680A (zh) * 2018-12-24 2019-02-22 江苏卓和药业有限公司 一种依维莫司的纯化方法
CN109485657A (zh) * 2018-12-24 2019-03-19 江苏卓和药业有限公司 一种替西罗莫司的纯化方法
MX2021010058A (es) 2019-02-20 2021-11-12 Ai Therapeutics Inc Formulaciones de rapamicina tópicas y su uso en el tratamiento de angiofibromas faciales y otros trastornos de la piel.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993749A (en) * 1974-04-12 1976-11-23 Ayerst Mckenna And Harrison Ltd. Rapamycin and process of preparation
US5362718A (en) * 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
US6277983B1 (en) * 2000-09-27 2001-08-21 American Home Products Corporation Regioselective synthesis of rapamycin derivatives
WO2005010010A1 (en) 2003-07-16 2005-02-03 Wyeth Cci-779 isomer c
RU2339639C2 (ru) * 2003-08-07 2008-11-27 Уайт Региоселективный синтез cci-779

Also Published As

Publication number Publication date
US20060199954A1 (en) 2006-09-07
AU2006218918A1 (en) 2006-09-08
ZA200707523B (en) 2010-02-24
RU2007130406A (ru) 2009-04-10
CA2599582A1 (en) 2006-09-08
WO2006093745A1 (en) 2006-09-08
NI200700225A (es) 2008-07-03
CN101133065A (zh) 2008-02-27
US7384953B2 (en) 2008-06-10
JP2008531686A (ja) 2008-08-14
KR20070107087A (ko) 2007-11-06
IL185077A0 (en) 2007-12-03
EP1853612A1 (en) 2007-11-14
MX2007010716A (es) 2008-01-16
CR9297A (es) 2008-01-21

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application