NO20073357L - 5-karboksamid substituerte tiazol derivater som reagerer med ionekanaler, i saerdeleshet med ionekanaler fra Kv familien - Google Patents
5-karboksamid substituerte tiazol derivater som reagerer med ionekanaler, i saerdeleshet med ionekanaler fra Kv familienInfo
- Publication number
- NO20073357L NO20073357L NO20073357A NO20073357A NO20073357L NO 20073357 L NO20073357 L NO 20073357L NO 20073357 A NO20073357 A NO 20073357A NO 20073357 A NO20073357 A NO 20073357A NO 20073357 L NO20073357 L NO 20073357L
- Authority
- NO
- Norway
- Prior art keywords
- ion channels
- react
- compounds
- family
- thiazole derivatives
- Prior art date
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- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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- General Chemical & Material Sciences (AREA)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63207204P | 2004-12-01 | 2004-12-01 | |
EP04447268 | 2004-12-01 | ||
US68691205P | 2005-06-03 | 2005-06-03 | |
EP05077177 | 2005-09-22 | ||
PCT/EP2005/056390 WO2006058905A1 (fr) | 2004-12-01 | 2005-12-01 | DÉRIVÉS DE THIAZOLE SUBSTITUÉ PAR DU 5-CARBOXAMIDO QUI INTERAGISSENT AVEC DES CANAUX IONIQUES, EN PARTICULIER AVEC DES CANAUX IONIQUES DE LA FAMILLE DE Kv |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20073357L true NO20073357L (no) | 2007-08-30 |
Family
ID=36084802
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20073357A NO20073357L (no) | 2004-12-01 | 2007-06-29 | 5-karboksamid substituerte tiazol derivater som reagerer med ionekanaler, i saerdeleshet med ionekanaler fra Kv familien |
Country Status (11)
Country | Link |
---|---|
US (1) | US20080125432A1 (fr) |
EP (1) | EP1819330A1 (fr) |
JP (1) | JP2008521862A (fr) |
KR (1) | KR20070094754A (fr) |
CN (1) | CN101098698A (fr) |
AU (1) | AU2005311251A1 (fr) |
BR (1) | BRPI0516915A (fr) |
CA (1) | CA2588517A1 (fr) |
MX (1) | MX2007006109A (fr) |
NO (1) | NO20073357L (fr) |
WO (1) | WO2006058905A1 (fr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI263497B (en) | 2002-03-29 | 2006-10-11 | Lilly Co Eli | Pyridinoylpiperidines as 5-HT1F agonists |
CA2614098A1 (fr) * | 2005-07-04 | 2007-01-11 | Dr. Reddy's Laboratories Ltd. | Derives de thiazole utiles comme activateurs de l'ampk |
US20090227612A1 (en) * | 2005-12-22 | 2009-09-10 | Boonsaeng Park | Aminopyrimidine Derivatives Inhibiting Protein Kinase Activity, Method For The Preparation Thereof And Pharmaceutical Composition Containing Same |
DE102006019589A1 (de) * | 2006-04-27 | 2007-10-31 | Sanofi-Aventis Deutschland Gmbh | Inhibitoren des TASK-1 und Task-3 Ionenkanals |
DE102006049527A1 (de) * | 2006-10-20 | 2008-04-24 | Sanofi-Aventis Deutschland Gmbh | Inhibitoren des TASK-1 und TASK-3 Ionenkanals |
EP2012758A2 (fr) * | 2006-04-27 | 2009-01-14 | Sanofi-Aventis Deutschland GmbH | Inhibiteurs du canal ionique task-1 et task-3 |
WO2007138110A2 (fr) * | 2006-06-01 | 2007-12-06 | Devgen N.V. | Composés interagissant avec des canaux ioniques, notamment des canaux ioniques de la famille kv |
WO2008138753A1 (fr) | 2007-05-11 | 2008-11-20 | F. Hoffmann-La Roche Ag | Hétarylanilines en tant que modulateurs de l'amyloïde bêta |
CA2705947C (fr) | 2007-11-16 | 2016-08-09 | Rigel Pharmaceuticals, Inc. | Composes de carboxamide, de sulfonamide et d'amine pour des troubles metaboliques |
ES2553340T3 (es) | 2007-12-12 | 2015-12-07 | Rigel Pharmaceuticals, Inc. | Compuestos de carboxamida, sulfonamida y amina para trastornos metabólicos |
JP5395808B2 (ja) | 2007-12-21 | 2014-01-22 | エフ.ホフマン−ラ ロシュ アーゲー | オレキシン受容体アンタゴニストとしてのヘテロアリール誘導体 |
JP5869222B2 (ja) | 2008-01-04 | 2016-02-24 | インテリカイン, エルエルシー | 特定の化学的実体、組成物および方法 |
US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
CA2703824C (fr) | 2008-01-11 | 2016-06-07 | F. Hoffmann-La Roche Ag | Modulateurs pour l'amyloide-beta |
MX2010008700A (es) | 2008-02-22 | 2010-08-30 | Hoffmann La Roche | Moduladores de beta-amiloide. |
WO2009132136A1 (fr) | 2008-04-23 | 2009-10-29 | Rigel Pharmaceuticals, Inc. | Composés de carboxamide pour le traitement de troubles métaboliques |
WO2009154769A1 (fr) * | 2008-06-19 | 2009-12-23 | Xcovery, Inc. | Composés de pyridazinecarboxamide substitués utiles en tant que composés inhibiteurs de kinase |
CA2729965A1 (fr) | 2008-07-14 | 2010-01-21 | Gilead Sciences, Inc. | Composes inhibiteurs heterocycliques condenses |
WO2010009139A2 (fr) | 2008-07-14 | 2010-01-21 | Gilead Colorado, Inc. | Composés inhibiteurs de pyrimidine imidazolyle |
WO2010009166A1 (fr) | 2008-07-14 | 2010-01-21 | Gilead Colorado, Inc. | Composés inhibiteurs de l’oxindolyle |
BRPI0916713A2 (pt) | 2008-07-28 | 2015-11-10 | Gilead Science Inc | compostos inibidores de histona desacetilase de cicloalquilideno e heterocicloalquilideno |
MX2011003246A (es) | 2008-10-09 | 2011-04-21 | Hoffmann La Roche | Moduladores de beta amiloide. |
MX2011004954A (es) | 2008-11-10 | 2011-05-30 | Hoffmann La Roche | Moduladores heterociclicos de gamma-secretasa. |
US20100222381A1 (en) | 2009-02-27 | 2010-09-02 | Hariprasad Vankayalapati | Cyclopentathiophene/cyclohexathiophene DNA methyltransferase inhibitors |
NZ596863A (en) | 2009-06-08 | 2014-02-28 | Gilead Sciences Inc | Alkanoylamino benzamide aniline hdac inhibitor compounds |
NZ596783A (en) | 2009-06-08 | 2014-01-31 | Gilead Sciences Inc | Cycloalkylcarbamate benzamide aniline hdac inhibitor compounds |
US8486967B2 (en) | 2010-02-17 | 2013-07-16 | Hoffmann-La Roche Inc. | Heteroaryl substituted piperidines |
US8697876B2 (en) | 2010-04-02 | 2014-04-15 | Colucid Pharmaceuticals, Inc. | Compositions and methods of synthesis of pyridinolypiperidine 5-HT1F agonists |
UA115767C2 (uk) | 2011-01-10 | 2017-12-26 | Інфініті Фармасьютікалз, Інк. | Способи отримання ізохінолінонів і тверді форми ізохінолінонів |
IN2014MN02089A (fr) * | 2012-03-20 | 2015-09-11 | Einstein Coll Med | |
US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
US9248122B2 (en) | 2012-11-28 | 2016-02-02 | Grünenthal GmbH | Heteroquinoline-3-carboxamides as KCNQ2/3 modulators |
EP2951156A1 (fr) | 2012-11-28 | 2015-12-09 | Grünenthal GmbH | Carboxamides spécifiques utilisés en tant que modulateurs des canaux kcnq2/3 |
AU2013351552A1 (en) * | 2012-11-28 | 2015-07-16 | Grünenthal GmbH | Substituted Amino-arylcarboxamides as KCNQ2/3 modulators |
US20150320755A1 (en) | 2014-04-16 | 2015-11-12 | Infinity Pharmaceuticals, Inc. | Combination therapies |
KR20190033526A (ko) | 2016-06-24 | 2019-03-29 | 인피니티 파마슈티칼스, 인코포레이티드 | 병용 요법 |
WO2018110669A1 (fr) | 2016-12-15 | 2018-06-21 | Ono Pharmaceutical Co., Ltd. | Activateur de canaux trek (canaux k+ associés à twik) |
WO2018122746A1 (fr) | 2016-12-28 | 2018-07-05 | Minoryx Therapeutics S.L. | Composés d'isoquinoléine, leurs méthodes de préparation et leurs utilisations thérapeutiques dans des maladies associées à l'altération de l'activité de la bêta galactosidase |
MY201325A (en) | 2017-06-01 | 2024-02-16 | Bristol Myers Squibb Co | Substituted nitrogen containing compounds |
PL3487839T3 (pl) * | 2017-06-20 | 2021-06-14 | Raqualia Pharma Inc. | Pochodne amidowe jako blokery Nav1.7 i Nav1.8 |
US20200123147A1 (en) | 2017-06-29 | 2020-04-23 | Bayer Aktiengesellschaft | Thiazole compounds useful as prmt5 inhibitors |
JP7277431B2 (ja) | 2017-07-11 | 2023-05-19 | バーテックス ファーマシューティカルズ インコーポレイテッド | ナトリウムチャネルのモジュレーターとしてのカルボキサミド |
EP3694833A4 (fr) * | 2017-10-09 | 2021-06-30 | Ramot at Tel-Aviv University Ltd. | Modulateurs de canaux trpv1 et ioniques potassiques et leurs utilisations |
TWI767148B (zh) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
TWI829107B (zh) | 2019-07-09 | 2024-01-11 | 美商美國禮來大藥廠 | 大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體,以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IS2334B (is) | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
US6043358A (en) | 1995-11-01 | 2000-03-28 | Merck & Co., Inc. | Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases |
GB9718913D0 (en) | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Substituted oxindole derivatives |
US6436989B1 (en) | 1997-12-24 | 2002-08-20 | Vertex Pharmaceuticals, Incorporated | Prodrugs of aspartyl protease inhibitors |
JP2001527062A (ja) | 1997-12-24 | 2001-12-25 | バーテックス ファーマシューティカルズ インコーポレイテッド | アスパルチルプロテアーゼインヒビターのプロドラッグ |
WO1999033792A2 (fr) | 1997-12-24 | 1999-07-08 | Vertex Pharmaceuticals Incorporated | Promedicaments des inhibiteurs de l'aspartyl-transferase |
WO1999033795A1 (fr) | 1997-12-24 | 1999-07-08 | Vertex Pharmaceuticals Incorporated | Promedicaments de la classe des inhibiteurs d'aspartyle protease |
MXPA01010292A (es) * | 1999-04-15 | 2002-10-23 | Squibb Bristol Myers Co | Inhibidores ciclicos de la proteina tirosina cinasa. |
US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
EP1506227B1 (fr) * | 2002-05-15 | 2006-08-02 | Devgen NV | Methodes d'identification et de mise au point de composes interagissant avec les canaux potassium potentiel-dependants de la famille kv4 |
EP1594854B1 (fr) * | 2003-02-06 | 2010-09-01 | Bristol-Myers Squibb Company | Composes a base de thiazolyle utilises comme inhibiteurs de kinases |
-
2005
- 2005-12-01 EP EP05818954A patent/EP1819330A1/fr not_active Withdrawn
- 2005-12-01 CA CA002588517A patent/CA2588517A1/fr not_active Abandoned
- 2005-12-01 WO PCT/EP2005/056390 patent/WO2006058905A1/fr active Application Filing
- 2005-12-01 US US11/792,030 patent/US20080125432A1/en not_active Abandoned
- 2005-12-01 JP JP2007543849A patent/JP2008521862A/ja not_active Withdrawn
- 2005-12-01 MX MX2007006109A patent/MX2007006109A/es not_active Application Discontinuation
- 2005-12-01 BR BRPI0516915-1A patent/BRPI0516915A/pt not_active IP Right Cessation
- 2005-12-01 AU AU2005311251A patent/AU2005311251A1/en not_active Abandoned
- 2005-12-01 KR KR1020077015118A patent/KR20070094754A/ko not_active Application Discontinuation
- 2005-12-01 CN CNA2005800460095A patent/CN101098698A/zh active Pending
-
2007
- 2007-06-29 NO NO20073357A patent/NO20073357L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20070094754A (ko) | 2007-09-21 |
US20080125432A1 (en) | 2008-05-29 |
AU2005311251A1 (en) | 2006-06-08 |
WO2006058905A1 (fr) | 2006-06-08 |
CN101098698A (zh) | 2008-01-02 |
EP1819330A1 (fr) | 2007-08-22 |
BRPI0516915A (pt) | 2008-03-11 |
MX2007006109A (es) | 2007-10-04 |
CA2588517A1 (fr) | 2006-06-08 |
JP2008521862A (ja) | 2008-06-26 |
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