NO20062452L - Stabile isotopmerkede aromatiske aminosyrer, fremgangsmate for inkorporering av disse i malprotein og fremgangsmate for NMR-strukturanalse av proteiner - Google Patents
Stabile isotopmerkede aromatiske aminosyrer, fremgangsmate for inkorporering av disse i malprotein og fremgangsmate for NMR-strukturanalse av proteinerInfo
- Publication number
- NO20062452L NO20062452L NO20062452A NO20062452A NO20062452L NO 20062452 L NO20062452 L NO 20062452L NO 20062452 A NO20062452 A NO 20062452A NO 20062452 A NO20062452 A NO 20062452A NO 20062452 L NO20062452 L NO 20062452L
- Authority
- NO
- Norway
- Prior art keywords
- atoms
- amino acid
- stable isotope
- carbon atoms
- labeled
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/54—Benzaldehyde
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
- G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/46—NMR spectroscopy
- G01R33/465—NMR spectroscopy applied to biological material, e.g. in vitro testing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- High Energy & Nuclear Physics (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003373304 | 2003-10-31 | ||
PCT/JP2004/016215 WO2005042469A1 (ja) | 2003-10-31 | 2004-11-01 | 安定同位体標識芳香族アミノ酸、その標的蛋白質への組み込み方法並びに蛋白質のnmr構造解析方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20062452L true NO20062452L (no) | 2006-07-28 |
Family
ID=34544086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20062452A NO20062452L (no) | 2003-10-31 | 2006-05-30 | Stabile isotopmerkede aromatiske aminosyrer, fremgangsmate for inkorporering av disse i malprotein og fremgangsmate for NMR-strukturanalse av proteiner |
Country Status (7)
Country | Link |
---|---|
US (2) | US7608248B2 (ja) |
EP (1) | EP1679302B1 (ja) |
JP (1) | JP5019280B2 (ja) |
CA (1) | CA2544305C (ja) |
DK (1) | DK1679302T3 (ja) |
NO (1) | NO20062452L (ja) |
WO (1) | WO2005042469A1 (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5137168B2 (ja) * | 2006-02-27 | 2013-02-06 | 独立行政法人科学技術振興機構 | 安定同位体標識脂肪族アミノ酸、その標的蛋白質への組み込み方法並びに蛋白質のnmr構造解析方法 |
WO2008146100A1 (en) * | 2007-06-01 | 2008-12-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method for absolute quantification of polypeptides |
US8945861B2 (en) | 2011-08-03 | 2015-02-03 | Pierce Biotechnology, Inc. | Methods for isotopically labeling biomolecules using mammalian cell-free extracts |
WO2014027473A1 (ja) | 2012-08-16 | 2014-02-20 | 大陽日酸株式会社 | 安定同位体標識脂肪族アミノ酸及びこれを利用したタンパク質のnmr構造解析法 |
WO2018081626A1 (en) * | 2016-10-28 | 2018-05-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Stable water isotope labeling and magnetic resonance imaging for visualization of rapidly dividing cells |
CN110057820B (zh) * | 2019-04-15 | 2021-04-30 | 中南大学 | 在线检测氯化氢合成炉氯氢配比的方法、系统及存储介质 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5393669A (en) * | 1993-02-05 | 1995-02-28 | Martek Biosciences Corp. | Compositions and methods for protein structural determinations |
US6111066A (en) * | 1997-09-02 | 2000-08-29 | Martek Biosciences Corporation | Peptidic molecules which have been isotopically substituted with 13 C, 15 N and 2 H in the backbone but not in the sidechains |
AU2002359993A1 (en) | 2001-12-19 | 2003-07-09 | Japan Science And Technology Agency | Stable isotope-labeled amino acid, method of integrating the same into target protein, method of nmr structural analysis of protein and process for producing site-selective stable isotope-labeled fumaric acid and tartaric acid |
-
2004
- 2004-11-01 CA CA2544305A patent/CA2544305C/en not_active Expired - Fee Related
- 2004-11-01 JP JP2005515191A patent/JP5019280B2/ja active Active
- 2004-11-01 WO PCT/JP2004/016215 patent/WO2005042469A1/ja active Application Filing
- 2004-11-01 EP EP04799421.5A patent/EP1679302B1/en not_active Not-in-force
- 2004-11-01 DK DK04799421.5T patent/DK1679302T3/da active
-
2006
- 2006-04-28 US US11/414,756 patent/US7608248B2/en active Active
- 2006-05-30 NO NO20062452A patent/NO20062452L/no not_active Application Discontinuation
-
2009
- 2009-09-14 US US12/559,089 patent/US8440169B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US8440169B2 (en) | 2013-05-14 |
WO2005042469A1 (ja) | 2005-05-12 |
US20060194328A1 (en) | 2006-08-31 |
EP1679302A4 (en) | 2007-08-22 |
JPWO2005042469A1 (ja) | 2007-05-10 |
US7608248B2 (en) | 2009-10-27 |
CA2544305C (en) | 2011-07-12 |
EP1679302B1 (en) | 2014-04-30 |
EP1679302A1 (en) | 2006-07-12 |
JP5019280B2 (ja) | 2012-09-05 |
DK1679302T3 (da) | 2014-06-10 |
CA2544305A1 (en) | 2005-05-12 |
US20100056799A1 (en) | 2010-03-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20062452L (no) | Stabile isotopmerkede aromatiske aminosyrer, fremgangsmate for inkorporering av disse i malprotein og fremgangsmate for NMR-strukturanalse av proteiner | |
Yamauchi et al. | Lysine hydroxylation and cross-linking of collagen | |
Asara et al. | Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry | |
JP4323429B2 (ja) | 新規なフルクトシルペプチドオキシダーゼとその利用 | |
Benson et al. | Non-heme Iron Proteins: X. The Amino Acid Sequences of Ferredoxins from Leucaena Glauca | |
DE50012021D1 (de) | Nucleinsauremoleküle mit spezifischer erkennung von nativem prpsc, herstellung und verwendung | |
WO1996039429A3 (en) | Serum protein produced exclusively in adipocytes | |
Fenwick et al. | Trapping and LC− MS Identification of Protein Radicals Formed in the Horse Heart Metmyoglobin− H2O2 Reaction | |
Imperiali et al. | Extended binding inhibitors of chymotrypsin that interact with leaving group subsites S1'-S3' | |
Cohen et al. | Covalent structural analysis of yeast inorganic pyrophosphatase. | |
Movellan et al. | Alpha protons as NMR probes in deuterated proteins | |
Tonelli et al. | Hydrogen exchange during cell-free incorporation of deuterated amino acids and an approach to its inhibition | |
Cleland et al. | Diagenetiforms: a new term to explain protein changes as a result of diagenesis in paleoproteomics | |
Chiappetta et al. | Quantitative identification of protein nitration sites | |
Van Eldik et al. | Characterization of a calcium-modulated protein from transformed chicken fibroblasts. | |
Kosen et al. | Two-dimensional proton NMR of three spin-labeled derivatives of bovine pancreatic trypsin inhibitor | |
ATE350659T1 (de) | Verfahren zur identifizierung von proben eines säugetiers als auch ein kit zur durchführung des verfahrens | |
Senn et al. | 15 N-labeled P22 c2 repressor for nuclear magnetic resonance studies of protein-DNA interactions | |
Gunther | Probing the free radicals formed in the metmyoglobin–hydrogen peroxide reaction | |
Procopio et al. | Proteome variation with collagen yield in ancient bone | |
Ruoppolo et al. | Analysis of transglutaminase protein substrates by functional proteomics | |
Goldstein et al. | Occurrence of glycylhydroxypyrolyl sequences in earthworm cuticle collagen | |
Chen et al. | Identification of the disulfide bonds of lysyl oxidase | |
Davydov et al. | Interactions of cytochrome P450 2B4 with NADPH-cytochrome P450 reductase studied by fluorescent probe | |
Chin et al. | The use of tributylphosphine and 4-(aminosulfonyl)-7-fluoro-2, 1, 3-benzoxadiazole in the study of protein sulfhydryls and disulfides |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |