NO20062262L - Cykloalkylderivater av 3-hydroksy-4-pyridinoner - Google Patents

Cykloalkylderivater av 3-hydroksy-4-pyridinoner

Info

Publication number
NO20062262L
NO20062262L NO20062262A NO20062262A NO20062262L NO 20062262 L NO20062262 L NO 20062262L NO 20062262 A NO20062262 A NO 20062262A NO 20062262 A NO20062262 A NO 20062262A NO 20062262 L NO20062262 L NO 20062262L
Authority
NO
Norway
Prior art keywords
alkyl
cycloalkyl
group
iron
proviso
Prior art date
Application number
NO20062262A
Other languages
English (en)
Norwegian (no)
Inventor
Tim Fat Tam
Michael Spino
Wanren Li
Yingsheng Wang
Yanqing Zhao
Birenkumar Hasmukhbhai Shah
Original Assignee
Apotex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apotex Inc filed Critical Apotex Inc
Publication of NO20062262L publication Critical patent/NO20062262L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
NO20062262A 2003-11-20 2006-05-19 Cykloalkylderivater av 3-hydroksy-4-pyridinoner NO20062262L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ529657A NZ529657A (en) 2003-11-20 2003-11-20 Iron chelating cycloalkyl derivatives of 3-hydroxy-4-pyridinones
PCT/CA2004/001986 WO2005049609A1 (fr) 2003-11-20 2004-11-18 Derives cycloalkyle de 3-hydroxy-4-pyridinones

Publications (1)

Publication Number Publication Date
NO20062262L true NO20062262L (no) 2006-08-11

Family

ID=31987701

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062262A NO20062262L (no) 2003-11-20 2006-05-19 Cykloalkylderivater av 3-hydroksy-4-pyridinoner

Country Status (16)

Country Link
US (2) US7410985B2 (fr)
EP (1) EP1687298B1 (fr)
KR (1) KR101166113B1 (fr)
CN (1) CN100448873C (fr)
AU (2) AU2004291184B2 (fr)
BR (1) BRPI0416703A (fr)
CA (1) CA2546781C (fr)
IL (1) IL175654A (fr)
MX (1) MXPA06005594A (fr)
NO (1) NO20062262L (fr)
NZ (1) NZ529657A (fr)
RU (1) RU2345992C2 (fr)
TN (1) TNSN06142A1 (fr)
UA (1) UA84178C2 (fr)
WO (1) WO2005049609A1 (fr)
ZA (1) ZA200604998B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2488034C (fr) 2004-11-19 2009-10-06 Apotex Inc. Procede de production de 3-hydroxy-n-alkyl-1-cycloalkyl-6-alkyl-4-oxo-1,4-dihydropyridine-2-carboxamide et d'analogues
DE102006043929B4 (de) * 2006-09-14 2016-10-06 Spawnt Private S.À.R.L. Verfahren zur Herstellung von festen Polysilanmischungen
EP2660239B1 (fr) * 2008-07-25 2016-11-23 VIIV Healthcare Company Composés chimiques en tant qu'intermédiaires synthétiques
CN101975767B (zh) * 2010-08-13 2012-12-05 同济大学 一种测定水环境中溶解性有机物与金属离子结合潜势的方法
EP2670417A4 (fr) * 2011-01-31 2014-07-09 Us Army Méthodes et compositions pour le traitement d'infections bactériennes par des chélateurs du fer
CN102603964B (zh) * 2012-01-15 2014-03-05 浙江工商大学 水溶性聚合物铁螯合剂及其制备方法和用途
CN105030819B (zh) * 2015-07-06 2019-04-05 中国科学技术大学 一种3-羟基-4-吡啶酮类高分子铁螯合剂的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308054D0 (en) 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
GB9217099D0 (en) 1992-08-12 1992-09-23 British Tech Group Pharmaceutical compositions
ATE299135T1 (de) 1995-09-29 2005-07-15 Novartis Pharma Gmbh Hydroxypyridinone
GB9711093D0 (en) * 1997-05-29 1997-07-23 British Tech Group Novel orally active iron (III) chelators
US6448273B1 (en) * 1997-05-29 2002-09-10 Btg International Limited Orally active iron (III) chelators
US6488273B2 (en) 2001-04-20 2002-12-03 Btm Corporation Powered pivot unit
US6426418B1 (en) * 2001-11-02 2002-07-30 Apotex, Inc. Processes for the manufacturing of 3-hydroxy-N,1,6-trialkyl-4-oxo-1,4-dihydropyridine-2-carboxamide
CA2379370A1 (fr) 2002-03-28 2003-09-28 Apotex Inc. Derives d'acide carboxylique et de 3-hydroxy-4-oxo-1,4-dihydropyridine utilises comme chelateurs du fer

Also Published As

Publication number Publication date
EP1687298A4 (fr) 2007-10-17
RU2006121547A (ru) 2007-12-27
ZA200604998B (en) 2007-09-26
EP1687298A1 (fr) 2006-08-09
KR20060096155A (ko) 2006-09-07
UA84178C2 (en) 2008-09-25
IL175654A (en) 2011-10-31
US20090170850A1 (en) 2009-07-02
IL175654A0 (en) 2006-09-05
NZ529657A (en) 2004-07-30
CN100448873C (zh) 2009-01-07
CA2546781C (fr) 2012-05-15
CA2546781A1 (fr) 2005-06-02
AU2004291184A1 (en) 2005-06-02
BRPI0416703A (pt) 2007-01-16
MXPA06005594A (es) 2006-12-19
WO2005049609A1 (fr) 2005-06-02
US20070082904A1 (en) 2007-04-12
AU2010246323A1 (en) 2010-12-09
RU2345992C2 (ru) 2009-02-10
KR101166113B1 (ko) 2012-07-27
US7410985B2 (en) 2008-08-12
TNSN06142A1 (en) 2007-11-15
AU2004291184B2 (en) 2010-08-26
US8097624B2 (en) 2012-01-17
CN1926135A (zh) 2007-03-07
EP1687298B1 (fr) 2012-12-26

Similar Documents

Publication Publication Date Title
NO20062262L (no) Cykloalkylderivater av 3-hydroksy-4-pyridinoner
NO20051165L (no) Benzotiazolderivater som har -adrenoerseptorantagonist aktivitet
NO20073357L (no) 5-karboksamid substituerte tiazol derivater som reagerer med ionekanaler, i saerdeleshet med ionekanaler fra Kv familien
NO20055316L (no) Nye heterocykliske forbindelser som er nyttige ved behandling av inflammatoriske og allergiske forstyrrelser, fremgangsmate for fremstilling derav og farmasoytiske sammensetninger som inneholder slike
NO20062633L (no) Pyrazolderivater som proteinkinasemodulatorer
NO20063446L (no) Tiazolderivater
AU2003215753A1 (en) Imidazopyridine derivatives as kinase inhibitors
NO20083542L (no) Nye kumarinderivater med antitumoraktivitet
WO2007122634A3 (fr) Inhibiteurs de kinase
NO20053133L (no) Kjemiske forbindelser.
NO20070557L (no) Ftalazinderivater som PARP-inhibitorer
DE69406649D1 (de) N-alkyl-2-substituierte atp-analoge
HUP0401009A2 (hu) 5-Hidroxitriptamin-6-ligandumokként alkalmazható 1-aril- vagy 1- alkil-szulfonilbenzazol-származékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
HUP0301336A2 (hu) Réztartalmú amin-oxidázok inhibitorai és alkalmazásuk gyógyszerkészítmények előállítására
EP1396493A4 (fr) Composes heterocycliques
NO20060314L (no) Nicotinamid-derivater anvendbare som PDE4-inhibitorer
NO20076145L (no) Ureadeviater, fremgangsmater for deres fremstilling og anvendelse derav
WO2001014330A3 (fr) Nouvelles phenylpiperazines
ATE300541T1 (de) Pyrazolopyridinderivate
NO20061045L (no) Imidazolderivater
NO20063865L (no) Heterocyklisk substituerte 7-amino-4-kinolon-3-karboksylsyrederivater, fremgangsmate for fremstilling derav og deres anvendelse som medikamenter
HUP0401575A2 (hu) Új vinil-karbonsav-származékok és ezek alkalmazása cukorbetegség ellen és ezeket tartalmazó gyógyszerkészítmények
SE0200919D0 (sv) Chemical compounds
GEP20074256B (en) Novel benzothiadiazine, process for their preparation and pharmaceutical compositions containing
MX2021011376A (es) Derivados de rapamicina que contienen isotiazolidina 1,1 - dioxido y 1,4 - butan sultona y sus usos.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application