NO20045229L - Fusjonsprotein fra HIV-regulatoriske/aksessoriske proteiner - Google Patents

Fusjonsprotein fra HIV-regulatoriske/aksessoriske proteiner

Info

Publication number
NO20045229L
NO20045229L NO20045229A NO20045229A NO20045229L NO 20045229 L NO20045229 L NO 20045229L NO 20045229 A NO20045229 A NO 20045229A NO 20045229 A NO20045229 A NO 20045229A NO 20045229 L NO20045229 L NO 20045229L
Authority
NO
Norway
Prior art keywords
proteins
fusion protein
nucleic acids
hiv
accessory proteins
Prior art date
Application number
NO20045229A
Other languages
English (en)
Norwegian (no)
Inventor
Paul Howley
Sonja Leyrer
Eva Felder
Original Assignee
Bavarian Nordic As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bavarian Nordic As filed Critical Bavarian Nordic As
Publication of NO20045229L publication Critical patent/NO20045229L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • C07K14/16HIV-1 ; HIV-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16311Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16311Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • AIDS & HIV (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO20045229A 2002-05-16 2004-11-29 Fusjonsprotein fra HIV-regulatoriske/aksessoriske proteiner NO20045229L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200200754 2002-05-16
PCT/EP2003/005039 WO2003097675A1 (en) 2002-05-16 2003-05-14 Fusion protein of hiv regulatory/accessory proteins

Publications (1)

Publication Number Publication Date
NO20045229L true NO20045229L (no) 2004-11-29

Family

ID=29433046

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20045229A NO20045229L (no) 2002-05-16 2004-11-29 Fusjonsprotein fra HIV-regulatoriske/aksessoriske proteiner

Country Status (24)

Country Link
US (7) US20050222388A1 (ja)
EP (2) EP1652857B9 (ja)
JP (3) JP2006502704A (ja)
KR (4) KR20100063126A (ja)
CN (3) CN1982332A (ja)
AT (2) ATE407143T1 (ja)
AU (2) AU2003240638B2 (ja)
BR (1) BR0309963A (ja)
CA (1) CA2483640A1 (ja)
CY (1) CY1108638T1 (ja)
DE (2) DE60323407D1 (ja)
DK (2) DK1506223T3 (ja)
EA (1) EA007154B1 (ja)
ES (2) ES2253675T3 (ja)
HK (1) HK1076822A1 (ja)
IL (3) IL164178A0 (ja)
MX (1) MXPA04010683A (ja)
NO (1) NO20045229L (ja)
NZ (2) NZ556144A (ja)
PL (2) PL372092A1 (ja)
PT (1) PT1652857E (ja)
SI (2) SI1506223T1 (ja)
UA (3) UA92788C2 (ja)
WO (1) WO2003097675A1 (ja)

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US7501127B2 (en) 2002-05-16 2009-03-10 Bavarian Nordic A/S Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara
EP1652857B9 (en) * 2002-05-16 2009-10-14 Bavarian Nordic A/S Fusion protein of HIV regulatory/accessory proteins
ATE520708T1 (de) 2003-03-28 2011-09-15 Us Gov Health & Human Serv Immunogenetische hiv-1 multi-klade, multivalente konstrukte und deren verwendung
CN101330830B (zh) 2005-10-18 2016-01-20 国家犹太健康中心 条件无限增殖化长期干细胞和制备和使用所述细胞的方法
AU2007345768B2 (en) * 2006-07-27 2013-08-01 Ligocyte Pharmaceuticals, Inc. Chimeric influenza virus-like particles
EP2044224A4 (en) * 2006-07-27 2011-04-13 Ligocyte Pharmaceuticals Inc CHIMERIC VIRUS TYPE PARTICLES
CA2723114C (en) 2008-05-16 2018-02-27 Taiga Biotechnologies, Inc. Antibodies and processes for preparing the same
EP2746387A1 (en) 2008-07-21 2014-06-25 Taiga Biotechnologies, Inc. Differentiated anucleated cells and method for preparing the same
ES2681478T3 (es) 2008-08-28 2018-09-13 Taiga Biotechnologies, Inc. Moduladores de MYC, métodos de uso de los mismos y métodos para identificar agentes que modulan MYC
EP2486138A1 (en) 2009-10-08 2012-08-15 Bavarian Nordic A/S Generation of a broad t-cell response in humans against hiv
US9358281B2 (en) * 2009-10-09 2016-06-07 New York University Methods, agents and peptides for inducing an innate immune response in HIV vaccination
US8920812B2 (en) 2009-11-03 2014-12-30 Takeda Vaccines, Inc. Chimeric RSV-F polypeptide and lentivirus or alpha-retrovirus Gag-based VLPS
EP2620446A1 (en) 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogens for HIV vaccination
CN114645015A (zh) 2012-07-20 2022-06-21 泰加生物工艺学公司 造血区室的增强的重建和自动重建
US9365825B2 (en) 2013-03-11 2016-06-14 Taiga Biotechnologies, Inc. Expansion of adult stem cells in vitro
US10272115B2 (en) 2013-03-11 2019-04-30 Taiga Biotechnologies, Inc. Production and use of red blood cells
WO2015192339A1 (zh) * 2014-06-18 2015-12-23 中山大学 一种嵌合载体及其制备方法和应用
CN104130331B (zh) * 2014-06-19 2017-06-06 中山大学 一种抗hiv‑1病毒药物及其制备和应用
FR3042121A1 (fr) 2015-10-08 2017-04-14 Jean-Marc Limacher Composition anti-tumorale
CN105330729A (zh) * 2015-11-18 2016-02-17 南京医科大学 一种人类免疫缺陷病毒Vpr蛋白的制备方法
US10583156B2 (en) 2016-12-02 2020-03-10 Taiga Biotechnologies, Inc. Nanoparticle formulations
US10149898B2 (en) 2017-08-03 2018-12-11 Taiga Biotechnologies, Inc. Methods and compositions for the treatment of melanoma
US11666651B2 (en) 2019-11-14 2023-06-06 Aelix Therapeutics, S.L. Prime/boost immunization regimen against HIV-1 utilizing a multiepitope T cell immunogen comprising Gag, Pol, Vif, and Nef epitopes

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Publication number Priority date Publication date Assignee Title
EP0942747A1 (en) * 1996-08-26 1999-09-22 Chiron Corporation Postinfection human immunodeficiency virus (hiv) vaccination therapy
GB9720585D0 (en) 1997-09-26 1997-11-26 Smithkline Beecham Biolog Vaccine
IT1297090B1 (it) 1997-12-01 1999-08-03 Barbara Ensoli Tat di hiv-1 o suoi derivati, da soli od in combinazione, a scopo vaccinale, profilattico e terapeutico, contro l'aids i tumori e le
FR2773156B1 (fr) * 1997-12-26 2000-03-31 Biovacs Inc Nouveaux immunogenes anti-retroviraux (toxoides), nouveaux procedes de preparation et application a la prevention et au traitement du sida
FI105105B (fi) 1998-02-27 2000-06-15 Finnish Immunotechnology Ltd O Itsereplikoiva DNA-vektori immunisoimiseksi HIV:ta vastaan
US7935805B1 (en) * 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
SK11122002A3 (sk) 2000-01-31 2003-01-09 Smithkline Beecham Biologicals S. A. Použitie HIV Tat proteínu a/alebo HIV Nef proteínu spolu s HIV gp120 proteínom a vakcína obsahujúca tieto proteíny
EP1418940A4 (en) * 2000-03-02 2006-09-20 Univ Emory DNA expression vectors and methods of use
US6544780B1 (en) * 2000-06-02 2003-04-08 Genphar, Inc. Adenovirus vector with multiple expression cassettes
ES2307640T3 (es) * 2000-07-14 2008-12-01 The Trustees Of The University Of Pennsylvania Vacunad de adn codificantes de proteinas accesorias del vih.
WO2002036806A2 (en) * 2000-11-01 2002-05-10 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Expression vectors able to elicit improved immune response and methods of using same
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EP1652857B9 (en) 2002-05-16 2009-10-14 Bavarian Nordic A/S Fusion protein of HIV regulatory/accessory proteins

Also Published As

Publication number Publication date
PL397252A1 (pl) 2012-04-10
EP1506223A1 (en) 2005-02-16
DE60323407D1 (de) 2008-10-16
KR20050010000A (ko) 2005-01-26
PL372092A1 (en) 2005-07-11
US8389275B2 (en) 2013-03-05
KR20110099058A (ko) 2011-09-05
HK1076822A1 (en) 2006-01-27
IL164178A0 (en) 2005-12-18
US20120142096A1 (en) 2012-06-07
CN1653085A (zh) 2005-08-10
NZ536499A (en) 2008-04-30
NZ556144A (en) 2008-04-30
US20060257974A1 (en) 2006-11-16
DK1652857T3 (da) 2009-01-05
AU2008252074A1 (en) 2009-01-08
JP2009178165A (ja) 2009-08-13
US20100047268A1 (en) 2010-02-25
US20050222388A1 (en) 2005-10-06
IL164178A (en) 2011-01-31
CN101108882A (zh) 2008-01-23
SI1652857T1 (sl) 2009-02-28
KR101196178B1 (ko) 2012-11-01
US20100047871A1 (en) 2010-02-25
JP2006502704A (ja) 2006-01-26
KR100996330B1 (ko) 2010-11-23
CN1982332A (zh) 2007-06-20
EA200401504A1 (ru) 2005-04-28
UA85373C2 (ru) 2009-01-26
UA92788C2 (ru) 2010-12-10
KR20120106894A (ko) 2012-09-26
PT1652857E (pt) 2008-12-12
EA007154B1 (ru) 2006-08-25
EP1652857B9 (en) 2009-10-14
US8435535B2 (en) 2013-05-07
DK1506223T3 (da) 2006-04-10
ATE407143T1 (de) 2008-09-15
ES2313166T3 (es) 2009-03-01
EP1652857A2 (en) 2006-05-03
US7569228B2 (en) 2009-08-04
DE60302356D1 (de) 2005-12-22
EP1652857A3 (en) 2007-03-14
ATE310016T1 (de) 2005-12-15
AU2008252074B2 (en) 2012-02-16
WO2003097675A1 (en) 2003-11-27
US20120142097A1 (en) 2012-06-07
EP1652857B1 (en) 2008-09-03
DE60302356T2 (de) 2006-08-03
SI1506223T1 (sl) 2006-04-30
KR20100063126A (ko) 2010-06-10
JP2010099084A (ja) 2010-05-06
US8143054B2 (en) 2012-03-27
MXPA04010683A (es) 2005-02-17
EP1506223B1 (en) 2005-11-16
BR0309963A (pt) 2005-02-22
CA2483640A1 (en) 2003-11-27
IL197304A0 (en) 2011-07-31
AU2003240638A1 (en) 2003-12-02
US20090280561A1 (en) 2009-11-12
US8147839B2 (en) 2012-04-03
US8137931B2 (en) 2012-03-20
ES2253675T3 (es) 2006-06-01
CY1108638T1 (el) 2014-04-09
CN1325512C (zh) 2007-07-11
UA82998C2 (ru) 2008-06-10
AU2003240638B2 (en) 2008-05-15

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