NO20045130L - Innretning og fremgangsmate til fremstilling av adenovirusvektorer - Google Patents

Innretning og fremgangsmate til fremstilling av adenovirusvektorer

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Publication number
NO20045130L
NO20045130L NO20045130A NO20045130A NO20045130L NO 20045130 L NO20045130 L NO 20045130L NO 20045130 A NO20045130 A NO 20045130A NO 20045130 A NO20045130 A NO 20045130A NO 20045130 L NO20045130 L NO 20045130L
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Norway
Prior art keywords
complementing cell
adenovirus vectors
gene
adenoviral vector
producing adenovirus
Prior art date
Application number
NO20045130A
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English (en)
Other versions
NO332108B1 (no
Inventor
Ronald Vogels
Abraham Bout
Original Assignee
Crucell Holland Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crucell Holland Bv filed Critical Crucell Holland Bv
Publication of NO20045130L publication Critical patent/NO20045130L/no
Publication of NO332108B1 publication Critical patent/NO332108B1/no

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/861—Adenoviral vectors
    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/6009—Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
    • C12N2810/6018—Adenoviridae
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor

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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
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Abstract

Det er beskrevet fremgangsmåter og midler for fremstillingen av adenovirale vektorer på komplementerende cellelinjer hvor den tidlige region 4 åpne leseramme 6(E4orf6)-kodende nukleinsyre er til stede i den adenovirale vektor og hvor E4-orf6-genproduktet er kompatibelt med et eller flere produkter av El-genproduktene fremskaffet av den komplementerende celle slik at den adenovirale vektor kan bli effektivt fremstilt av den komplementerende celle.
NO20045130A 2002-04-25 2004-11-24 Innretning og fremgangsmate til fremstilling av adenovirusvektorer NO332108B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL0200280 2002-04-25
PCT/EP2003/050125 WO2003104467A1 (en) 2002-04-25 2003-04-24 Means and methods for the production of adenovirus vectors

Publications (2)

Publication Number Publication Date
NO20045130L true NO20045130L (no) 2005-01-18
NO332108B1 NO332108B1 (no) 2012-06-25

Family

ID=29728828

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20045130A NO332108B1 (no) 2002-04-25 2004-11-24 Innretning og fremgangsmate til fremstilling av adenovirusvektorer

Country Status (23)

Country Link
US (2) US7468181B2 (no)
EP (1) EP1497438B1 (no)
JP (1) JP4495587B2 (no)
KR (1) KR101021387B1 (no)
CN (1) CN100497639C (no)
AT (1) ATE447037T1 (no)
AU (1) AU2003271737B2 (no)
BR (1) BR0308783A (no)
CA (1) CA2477954C (no)
DE (1) DE60329835D1 (no)
DK (1) DK1497438T3 (no)
EA (1) EA010828B1 (no)
ES (1) ES2335657T3 (no)
HK (1) HK1068371A1 (no)
IL (2) IL164803A0 (no)
MX (1) MXPA04008891A (no)
NO (1) NO332108B1 (no)
NZ (1) NZ534866A (no)
PL (1) PL215165B1 (no)
PT (1) PT1497438E (no)
SI (1) SI1497438T1 (no)
WO (1) WO2003104467A1 (no)
ZA (1) ZA200406942B (no)

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CN100497639C (zh) 2009-06-10

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