NO20031922L - Faseoverföringskatalysert glykosidering av en indolkarbazol - Google Patents

Faseoverföringskatalysert glykosidering av en indolkarbazol

Info

Publication number
NO20031922L
NO20031922L NO20031922A NO20031922A NO20031922L NO 20031922 L NO20031922 L NO 20031922L NO 20031922 A NO20031922 A NO 20031922A NO 20031922 A NO20031922 A NO 20031922A NO 20031922 L NO20031922 L NO 20031922L
Authority
NO
Norway
Prior art keywords
indolcarbazole
phase transfer
transfer catalyzed
catalyzed glycosidation
glycosidation
Prior art date
Application number
NO20031922A
Other languages
English (en)
Norwegian (no)
Other versions
NO20031922D0 (no
Inventor
Daniel E Petrillo
Steven A Weissman
Kai Rossen
Shouichi Hiraga
Nobuya Satake
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of NO20031922D0 publication Critical patent/NO20031922D0/no
Publication of NO20031922L publication Critical patent/NO20031922L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20031922A 2000-10-31 2003-04-29 Faseoverföringskatalysert glykosidering av en indolkarbazol NO20031922L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24467500P 2000-10-31 2000-10-31
PCT/US2001/047603 WO2002036601A2 (en) 2000-10-31 2001-10-26 Phase transfer catalyzed glycosidation of an indolocarbazole

Publications (2)

Publication Number Publication Date
NO20031922D0 NO20031922D0 (no) 2003-04-29
NO20031922L true NO20031922L (no) 2003-06-27

Family

ID=22923680

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20031922A NO20031922L (no) 2000-10-31 2003-04-29 Faseoverföringskatalysert glykosidering av en indolkarbazol

Country Status (20)

Country Link
US (2) US6555677B2 (cs)
EP (1) EP1333826A2 (cs)
JP (1) JP3554560B2 (cs)
KR (1) KR100813086B1 (cs)
CN (1) CN1240380C (cs)
AU (2) AU2002228945B2 (cs)
BG (1) BG107737A (cs)
BR (1) BR0115036A (cs)
CA (1) CA2426815A1 (cs)
CZ (1) CZ20031209A3 (cs)
EA (1) EA005209B1 (cs)
HU (1) HUP0302923A3 (cs)
IL (1) IL155543A0 (cs)
IS (1) IS6791A (cs)
MX (1) MXPA03003871A (cs)
NO (1) NO20031922L (cs)
NZ (1) NZ525398A (cs)
PL (1) PL365574A1 (cs)
WO (1) WO2002036601A2 (cs)
ZA (1) ZA200303198B (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555677B2 (en) * 2000-10-31 2003-04-29 Merck & Co., Inc. Phase transfer catalyzed glycosidation of an indolocarbazole
CA2734052A1 (en) * 2003-05-30 2005-01-13 Pharmasset, Inc. Modified fluorinated nucleoside analogues
JPWO2005026185A1 (ja) * 2003-09-16 2006-11-16 萬有製薬株式会社 抗腫瘍性新規インドロピロロカルバゾール誘導体
CA2567948A1 (en) * 2004-05-28 2005-12-08 Banyu Pharmaceutical Co., Ltd. Process for producing indolopyrrolocarbazole derivative
CN101023094B (zh) * 2004-07-21 2011-05-18 法莫赛特股份有限公司 烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
CA2580457C (en) 2004-09-14 2014-11-04 Pharmasset, Inc. Preparation of 2'­fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives
US7537774B2 (en) * 2005-12-23 2009-05-26 Orion Therapeautics, Llc Therapeutic formulation
US7964580B2 (en) 2007-03-30 2011-06-21 Pharmasset, Inc. Nucleoside phosphoramidate prodrugs
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
CL2009002208A1 (es) 2008-12-23 2010-10-29 Gilead Pharmasset Llc Un compuesto (2s)-2-((((2r,3r,4r,5r)-5-(2-amino-6-etoxi-9h-purin-9-il)-4-fluoro-3-hidroxi-4-metiltetrahidrofuran-2-il)metoxi)(hidroxi)fosforilamino)propanoico, inhibidores de la replicacion de arn viral; composicion farmaceutica; y su uso en el tratamiento de infeccion por hepatitis c, virus del nilo occidental, entre otras.
EP3222628A1 (en) 2008-12-23 2017-09-27 Gilead Pharmasset LLC Nucleoside phosphoramidates
MX2011006892A (es) 2008-12-23 2011-07-20 Pharmasset Inc Sintesis de nucleosidos de purina.
US8618076B2 (en) 2009-05-20 2013-12-31 Gilead Pharmasset Llc Nucleoside phosphoramidates
TWI576352B (zh) 2009-05-20 2017-04-01 基利法瑪席特有限責任公司 核苷磷醯胺
PL3290428T3 (pl) 2010-03-31 2022-02-07 Gilead Pharmasset Llc Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
ES2551944T3 (es) 2010-03-31 2015-11-24 Gilead Pharmasset Llc (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihidropirimidin-1-(2H)-il)-4-fluoro-3-hidroxi-4-metiltetrahidrofuran-2-il)metoxi)(fenoxi)fosforil)amino)propanoato de isopropilo cristalino
WO2012075140A1 (en) 2010-11-30 2012-06-07 Pharmasset, Inc. Compounds
US8889159B2 (en) 2011-11-29 2014-11-18 Gilead Pharmasset Llc Compositions and methods for treating hepatitis C virus
SI3650014T1 (sl) 2013-08-27 2022-01-31 Gilead Pharmasset Llc Formulacija kombinacije dveh protivirusnih spojin

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808613A (en) 1986-11-21 1989-02-28 Bristol-Myers Company Rebeccamycin derivative containing pharmaceutical composition
GB8818430D0 (en) * 1988-08-03 1988-09-07 Tate & Lyle Plc Process
US5668271A (en) 1991-11-29 1997-09-16 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
US5591842A (en) 1991-11-29 1997-01-07 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
US5437996A (en) 1992-11-24 1995-08-01 Banyu Pharmaceutical Co., Ltd. Microtetraspora strain for preparation of indolopyrrolocarbazole derivatives
NZ245203A (en) 1991-11-29 1997-07-27 Banyu Pharma Co Ltd 5h-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h)-dione derivatives substituted in position-13 by a pentose or hexose group; corresponding indolo-furano(anhydride)intermediates
US5589365A (en) 1991-11-29 1996-12-31 Banyu Pharmaceutical Co., Ltd. Process for producing glycosylated indolopyrrolocarbazole derivatives by culturing certain microorganisms
US5468872A (en) 1993-09-16 1995-11-21 Cephalon, Inc. K-252a functional derivatives potentiate neurotrophin-3 for the treatment of neurological disorders
EP0675125A1 (en) 1994-03-18 1995-10-04 Kyowa Hakko Kogyo Co., Ltd. A therapeutic agent for thrombocytopenia and indolocarbazole derivatives
US5922860A (en) * 1994-05-09 1999-07-13 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
US5804564A (en) 1994-05-09 1998-09-08 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
FR2750135B1 (fr) * 1996-06-20 1998-08-14 Ceca Sa Acides fluoroalkyl glycosides uroniques et lactones-6(3) correspondantes, preparation et utilisations
AU710669B2 (en) 1996-08-22 1999-09-23 Bristol-Myers Squibb Company Cytotoxic amino sugar and related sugar derivatives of indolopyrrolocarbazoles
US6555677B2 (en) * 2000-10-31 2003-04-29 Merck & Co., Inc. Phase transfer catalyzed glycosidation of an indolocarbazole

Also Published As

Publication number Publication date
EA005209B1 (ru) 2004-12-30
MXPA03003871A (es) 2003-07-28
CZ20031209A3 (cs) 2003-10-15
BR0115036A (pt) 2004-02-25
HUP0302923A3 (en) 2005-02-28
WO2002036601A2 (en) 2002-05-10
CN1240380C (zh) 2006-02-08
EP1333826A2 (en) 2003-08-13
HUP0302923A2 (hu) 2003-12-29
AU2894502A (en) 2002-05-15
NO20031922D0 (no) 2003-04-29
JP3554560B2 (ja) 2004-08-18
CN1482908A (zh) 2004-03-17
WO2002036601A3 (en) 2002-11-28
CA2426815A1 (en) 2002-05-10
KR100813086B1 (ko) 2008-03-17
JP2004513131A (ja) 2004-04-30
ZA200303198B (en) 2004-04-23
BG107737A (bg) 2004-01-30
US20020058803A1 (en) 2002-05-16
NZ525398A (en) 2004-12-24
EA200300525A1 (ru) 2003-08-28
US6555677B2 (en) 2003-04-29
IL155543A0 (en) 2003-11-23
AU2002228945B2 (en) 2006-02-02
IS6791A (is) 2003-04-16
KR20030082545A (ko) 2003-10-22
US20040024196A1 (en) 2004-02-05
HK1064053A1 (en) 2005-01-21
PL365574A1 (en) 2005-01-10

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application