NO2002002I2 - Ferukarbotran - Google Patents

Ferukarbotran

Info

Publication number
NO2002002I2
NO2002002I2 NO2002002C NO2002002C NO2002002I2 NO 2002002 I2 NO2002002 I2 NO 2002002I2 NO 2002002 C NO2002002 C NO 2002002C NO 2002002 C NO2002002 C NO 2002002C NO 2002002 I2 NO2002002 I2 NO 2002002I2
Authority
NO
Norway
Prior art keywords
ferukarbotran
Prior art date
Application number
NO2002002C
Other languages
English (en)
Original Assignee
Meito Sangyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP16633491 priority Critical
Priority to PCT/JP1992/000735 priority patent/WO1992022586A1/ja
Application filed by Meito Sangyo Kk filed Critical Meito Sangyo Kk
Publication of NO2002002I2 publication Critical patent/NO2002002I2/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1827Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
    • A61K49/1851Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule
    • A61K49/1863Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule the organic macromolecular compound being a polysaccharide or derivative thereof, e.g. chitosan, chitin, cellulose, pectin, starch
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/541,3-Diazines; Hydrogenated 1,3-diazines
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/661,3,5-Triazines, not hydrogenated and not substituted at the ring nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulfur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/30Only oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/6512Six-membered rings having the nitrogen atoms in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00Use of inorganic substances as compounding ingredients
    • C08K3/18Oxygen-containing compounds, e.g. metal carbonyls
    • C08K3/20Oxides; Hydroxides
    • C08K3/22Oxides; Hydroxides of metals
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L3/00Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
    • C08L3/04Starch derivatives, e.g. crosslinked derivatives
    • C08L3/10Oxidised starch
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/14Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar alpha-D-Glucans, i.e. having alpha 1,n (n=3,4,6) linkages between saccharide units, e.g. pullulan
    • G01N2400/16Starch, amylose, amylopectin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/14Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar alpha-D-Glucans, i.e. having alpha 1,n (n=3,4,6) linkages between saccharide units, e.g. pullulan
    • G01N2400/22Dextran
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/20Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/30Magnetic particle immunoreagent carriers the magnetic material being dispersed in the polymer composition before their conversion into particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/80Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/86Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids the coating being pre-functionalised for attaching immunoreagents, e.g. aminodextran
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
NO2002002C 1991-06-11 2002-05-16 Ferukarbotran NO2002002I2 (no)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP16633491 1991-06-11
PCT/JP1992/000735 WO1992022586A1 (fr) 1991-06-11 1992-06-08 Composite oxyde comprenant du carboxypolysaccharide hydrosoluble et de l'oxyde de fer magnetique

Publications (1)

Publication Number Publication Date
NO2002002I2 true NO2002002I2 (no) 2004-09-27

Family

ID=15829440

Family Applications (2)

Application Number Title Priority Date Filing Date
NO930465A NO304351B1 (no) 1991-06-11 1993-02-10 Oksydert kompleks av et vannoppl°selig karboksydpolysakkarid og magnetisk jernoksyd, samt kontrastmedier derav
NO2002002C NO2002002I2 (no) 1991-06-11 2002-05-16 Ferukarbotran

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO930465A NO304351B1 (no) 1991-06-11 1993-02-10 Oksydert kompleks av et vannoppl°selig karboksydpolysakkarid og magnetisk jernoksyd, samt kontrastmedier derav

Country Status (13)

Country Link
US (1) US5424419A (no)
EP (1) EP0543020B1 (no)
JP (1) JP2939336B2 (no)
AT (1) AT161546T (no)
AU (1) AU652060C (no)
CA (1) CA2089148C (no)
DE (2) DE69223748T2 (no)
DK (1) DK0543020T3 (no)
ES (1) ES2110500T3 (no)
LU (1) LU91004I2 (no)
NL (1) NL300087I1 (no)
NO (2) NO304351B1 (no)
WO (1) WO1992022586A1 (no)

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US5766572A (en) * 1992-08-05 1998-06-16 Meito Sangyo Kabushiki Kaisha Water-soluble carboxypolysaccharide-magnetic iron oxide complex having a small particle diameter
DE4428851C2 (de) * 1994-08-04 2000-05-04 Diagnostikforschung Inst Eisen enthaltende Nanopartikel, ihre Herstellung und Anwendung in der Diagnostik und Therapie
JPH10506121A (ja) * 1994-09-27 1998-06-16 ニコムド イメージング エイ/エス コントラスト剤
DE19509694A1 (de) * 1995-03-08 1996-09-19 Schering Ag Verwendung von Magnetiten zur Bestimmung der Perfusion von menschlichem Gewebe mittels MR-Diagnostik
GB9600427D0 (en) * 1996-01-10 1996-03-13 Nycomed Imaging As Contrast media
ES2239349T3 (es) 1996-01-10 2005-09-16 Amersham Health As Medio de contraste.
CN1151846C (zh) 1996-08-05 2004-06-02 舍林公开股份有限公司 核磁共振断层扫描成像用造影剂的制备方法
DE69725746T2 (de) * 1996-08-30 2004-05-13 Maruno, Shigeo, Kani Zusammensetzung enthaltend ein polysaccharidderivat und magnetisches eisenoxid
EP0967227A1 (en) * 1998-06-04 1999-12-29 Mitsubishi Gas Chemical Company, Inc. Process for producing carboxypolysaccharide
KR100384311B1 (ko) * 1998-11-13 2003-05-16 미쯔이카가쿠 가부시기가이샤 분산안정성이 우수한 유기중합체/무기미립자분산수용액 및그 용도
US6725078B2 (en) * 2000-01-31 2004-04-20 St. Louis University System combining proton beam irradiation and magnetic resonance imaging
US7169618B2 (en) * 2000-06-28 2007-01-30 Skold Technology Magnetic particles and methods of producing coated magnetic particles
US20030124194A1 (en) * 2002-01-02 2003-07-03 Gaw Debra A. Amine functionalized superparamagnetic nanoparticles for the synthesis of bioconjugates and uses therefor
US20030185757A1 (en) * 2002-03-27 2003-10-02 Mayk Kresse Iron-containing nanoparticles with double coating and their use in diagnosis and therapy
US7030208B2 (en) * 2002-04-11 2006-04-18 Carbomer, Inc. Biocompatible materials and probes
WO2003086474A2 (en) * 2002-04-11 2003-10-23 Carbomer, Inc Fluorinated or paramagnetic alginate polymer, annexin paramagnetic conjugate, and their use as contrasting agent in mri
DE10324710A1 (de) * 2003-05-30 2004-12-16 Supramol Parenteral Colloids Gmbh Stärkederivatkomplexe
EP1932009B1 (en) 2005-08-31 2014-02-12 T2 Biosystems, Inc. Nmr device for detection of analytes involving magnetic particles
US9913917B2 (en) 2005-12-22 2018-03-13 Visen Medical, Inc. Biocompatible fluorescent metal oxide nanoparticles
CZ301067B6 (cs) * 2006-02-24 2009-10-29 Ústav makromolekulární chemie AV CR Superparamagnetické nanocástice na bázi oxidu železa s modifikovaným povrchem, zpusob jejich prípravy a použití
US20070258907A1 (en) * 2006-04-24 2007-11-08 Davis Mark E Polymer-coated paramagnetic particles
US7892520B2 (en) * 2006-07-31 2011-02-22 The Hong Kong University Of Science And Technology Solid-state synthesis of iron oxide nanoparticles
WO2008057578A1 (en) * 2006-11-08 2008-05-15 T2 Biosystems, Inc. Nmr systems for in vivo detection of analytes
WO2008108505A1 (ja) 2007-03-07 2008-09-12 Japan As Represented By President Of International Medical Center Of Japan 新規核内移行ペプチド
JP2010540929A (ja) * 2007-09-28 2010-12-24 ティツー・バイオシステムズ・インコーポレーテッドT2 Biosystems,Inc. プラスチック製サンプル容器を用いるnmr装置による診断
EP2217951A4 (en) 2007-11-06 2011-05-18 T2 Biosystems Inc Small magnet and rf coil for magnetic resonance relaxometry
JP5926958B2 (ja) 2008-10-29 2016-05-25 ティー2 バイオシステムズ,インコーポレーテッド 凝固時間のnmr検出
IT1398263B1 (it) * 2010-03-04 2013-02-22 Monzani Nanoparticelle magnetiche di ossido di ferro a dimensione controllata per la diagnosi ed il trattamento di neoplasie avanzate e metastatiche
US20120021010A1 (en) * 2010-04-29 2012-01-26 University Of Calcutta Antiplatelet agent and methods of using the same
ES2576927T3 (es) 2010-10-22 2016-07-12 T2 Biosystems, Inc. NMR systems and methods for rapid analyte detection
US8409807B2 (en) 2010-10-22 2013-04-02 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
JP6122848B2 (ja) 2011-07-13 2017-04-26 ティー2 バイオシステムズ,インコーポレーテッド 血餅形成をモニタリングするためのnmr法
EP2748651B1 (en) 2011-09-21 2017-08-30 T2 Biosystems, Inc. Nmr methods for endotoxin analysis
CN102429865B (zh) * 2011-12-01 2013-07-17 广西壮族自治区化工研究院 一种特微分子右旋糖酐铁注射液的制备方法
EP2647389A1 (en) 2012-04-04 2013-10-09 Charité - Universitätsmedizin Berlin Magnetic nanoparticle dispersion, its preparation and diagnostic and therapeutic use
WO2013158281A1 (en) 2012-04-20 2013-10-24 T2 Biosystems, Inc. Compositions and methods for detection of candida species
CA2893591A1 (en) 2012-12-07 2014-06-12 T2 Biosystems, Inc. Methods for monitoring tight clot formation
CN105600832A (zh) * 2014-11-19 2016-05-25 正大天晴药业集团股份有限公司 一种经修饰的超顺磁性氧化铁的制备方法

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Also Published As

Publication number Publication date
AU652060B2 (en) 1994-08-11
LU91004A9 (no)
ES2110500T3 (es) 1998-02-16
WO1992022586A1 (fr) 1992-12-23
JP2939336B2 (ja) 1999-08-25
EP0543020B1 (en) 1997-12-29
DE10199064I1 (de) 2002-02-21
NO304351B1 (no) 1998-12-07
JPH07502028A (no) 1995-03-02
US5424419A (en) 1995-06-13
NL300087I1 (nl) 2002-07-01
LU91004I2 (en) 2003-03-24
DE69223748D1 (de) 1998-02-05
AU1884692A (en) 1993-01-12
CA2089148A1 (en) 1992-12-12
DE10199064I2 (de) 2004-07-12
EP0543020A1 (en) 1993-05-26
NO930465D0 (no) 1993-02-10
NO930465L (no) 1993-04-06
DK0543020T3 (da) 1998-08-31
DE69223748T2 (de) 1998-04-23
EP0543020A4 (en) 1993-12-01
AU652060C (en) 2004-04-22
CA2089148C (en) 2003-08-05
AT161546T (de) 1998-01-15

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