NO20014011L - Glukosedehydrogenasefusjonsproteiner og deres anvendelse i ekspresjonssystemer - Google Patents

Glukosedehydrogenasefusjonsproteiner og deres anvendelse i ekspresjonssystemer

Info

Publication number
NO20014011L
NO20014011L NO20014011A NO20014011A NO20014011L NO 20014011 L NO20014011 L NO 20014011L NO 20014011 A NO20014011 A NO 20014011A NO 20014011 A NO20014011 A NO 20014011A NO 20014011 L NO20014011 L NO 20014011L
Authority
NO
Norway
Prior art keywords
expression systems
fusion proteins
glucose dehydrogenase
dehydrogenase fusion
protein
Prior art date
Application number
NO20014011A
Other languages
English (en)
Other versions
NO20014011D0 (no
Inventor
Winfried Linxweiler
Christa Burger
Oliver Poeschke
Uwe Hofmann
Andrea Wolf
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20014011D0 publication Critical patent/NO20014011D0/no
Publication of NO20014011L publication Critical patent/NO20014011L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Oppfinnelsen vedrører nye rekombi-nante fusjonsproteiner som inneholder en proteinsekvens som har den biolog-iske aktivitet til glukosedehydrogenase som en av bestanddelene, og deres anvendelse for enkel og effektiv påvis-ning av enhver type proteiner/poly-peptider i SDS-PAGE-geler, og for hurtig optimalisering av ekspresjons-systemer som kan uttrykke de ovenfor nevnte proteiner/polypeptider.
NO20014011A 1999-02-19 2001-08-17 Glukosedehydrogenasefusjonsproteiner og deres anvendelse i ekspresjonssystemer NO20014011L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19906920 1999-02-19
PCT/EP2000/000978 WO2000049039A2 (de) 1999-02-19 2000-02-08 Glucose-dehydrogenase-fusionsproteine und ihre verwendung in expressionssystemen

Publications (2)

Publication Number Publication Date
NO20014011D0 NO20014011D0 (no) 2001-08-17
NO20014011L true NO20014011L (no) 2001-10-02

Family

ID=7897979

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20014011A NO20014011L (no) 1999-02-19 2001-08-17 Glukosedehydrogenasefusjonsproteiner og deres anvendelse i ekspresjonssystemer

Country Status (16)

Country Link
US (1) US20050112744A1 (no)
EP (1) EP1155130A2 (no)
JP (1) JP2002538782A (no)
KR (1) KR20010103017A (no)
CN (1) CN1340104A (no)
AR (1) AR022630A1 (no)
AU (1) AU771320B2 (no)
BR (1) BR0008370A (no)
CA (1) CA2368461A1 (no)
CZ (1) CZ20012739A3 (no)
HU (1) HUP0200285A2 (no)
NO (1) NO20014011L (no)
PL (1) PL350574A1 (no)
SK (1) SK11742001A3 (no)
WO (1) WO2000049039A2 (no)
ZA (1) ZA200107686B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060246046A1 (en) * 2001-12-21 2006-11-02 Helmut Giersiefen Modified tridegins, production and use thereof as transglutaminase inihibitors
JP2007502114A (ja) * 2003-08-11 2007-02-08 コデクシス， インコーポレイテッド 改良されたグルコースデヒドロゲナーゼポリペプチドおよび関連ポリヌクレオチド
EP2010649B1 (en) * 2006-04-13 2017-03-08 Roche Diabetes Care GmbH Improved mutants of pyrroloquinoline quinone dependent soluble glucose dehydrogenase
CN110894504A (zh) * 2019-12-20 2020-03-20 武汉茵慕生物科技有限公司 强化表达葡萄糖6-磷酸脱氢酶的地衣芽胞杆菌在异源蛋白生产中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60141299A (ja) * 1983-12-28 1985-07-26 Wako Pure Chem Ind Ltd 脱水素酵素の活性度測定法
JPS63230098A (ja) * 1987-03-18 1988-09-26 Fujitsu Ltd 酵素の分析方法
DE3711881A1 (de) * 1987-04-08 1988-10-27 Merck Patent Gmbh Verfahren zur herstellung von glucosedehydrogenase aus bacillus megaterium
IL131241A0 (en) * 1997-02-07 2001-01-28 Kaneka Corp Novel carbonyl reductase gene coding same and method for using such reductase and gene
US6399859B1 (en) * 1997-12-10 2002-06-04 Pioneer Hi-Bred International, Inc. Plant uridine diphosphate-glucose dehydrogenase genes, proteins, and uses thereof

Also Published As

Publication number Publication date
US20050112744A1 (en) 2005-05-26
ZA200107686B (en) 2002-12-18
SK11742001A3 (sk) 2002-03-05
KR20010103017A (ko) 2001-11-17
AU771320B2 (en) 2004-03-18
CN1340104A (zh) 2002-03-13
AU2546800A (en) 2000-09-04
EP1155130A2 (de) 2001-11-21
JP2002538782A (ja) 2002-11-19
CZ20012739A3 (cs) 2001-11-14
PL350574A1 (en) 2002-12-30
AR022630A1 (es) 2002-09-04
WO2000049039A2 (de) 2000-08-24
BR0008370A (pt) 2001-11-06
NO20014011D0 (no) 2001-08-17
WO2000049039A3 (de) 2000-12-14
CA2368461A1 (en) 2000-08-24
HUP0200285A2 (hu) 2002-05-29

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