NO20005782L - Hydroksaminsyrederivater som antibakterielle midler - Google Patents

Hydroksaminsyrederivater som antibakterielle midler

Info

Publication number
NO20005782L
NO20005782L NO20005782A NO20005782A NO20005782L NO 20005782 L NO20005782 L NO 20005782L NO 20005782 A NO20005782 A NO 20005782A NO 20005782 A NO20005782 A NO 20005782A NO 20005782 L NO20005782 L NO 20005782L
Authority
NO
Norway
Prior art keywords
group
alkyl
acid derivatives
antibacterial agents
hydroxamic acid
Prior art date
Application number
NO20005782A
Other languages
English (en)
Norwegian (no)
Other versions
NO20005782D0 (no
Inventor
Michael George Hunter
Raymond Paul Beckett
John Martin Clements
Mark Whittaker
Zoe Marie Spavold
Original Assignee
British Biotech Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharm filed Critical British Biotech Pharm
Publication of NO20005782D0 publication Critical patent/NO20005782D0/no
Publication of NO20005782L publication Critical patent/NO20005782L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyridine Compounds (AREA)
NO20005782A 1998-05-16 2000-11-15 Hydroksaminsyrederivater som antibakterielle midler NO20005782L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9810464.9A GB9810464D0 (en) 1998-05-16 1998-05-16 Hydroxamic acid derivatives
PCT/GB1999/001541 WO1999059568A1 (en) 1998-05-16 1999-05-14 Hydroxamic acid derivatives as antibacterials

Publications (2)

Publication Number Publication Date
NO20005782D0 NO20005782D0 (no) 2000-11-15
NO20005782L true NO20005782L (no) 2001-01-15

Family

ID=10832125

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005782A NO20005782L (no) 1998-05-16 2000-11-15 Hydroksaminsyrederivater som antibakterielle midler

Country Status (23)

Country Link
US (3) US6441042B1 (pt)
EP (2) EP1079819B1 (pt)
JP (1) JP2002515427A (pt)
KR (1) KR100634089B1 (pt)
CN (1) CN1300210A (pt)
AT (1) ATE347356T1 (pt)
AU (1) AU754063B2 (pt)
BR (1) BR9910488A (pt)
CA (1) CA2332713C (pt)
CY (1) CY1106452T1 (pt)
DE (1) DE69934309T2 (pt)
DK (1) DK1079819T3 (pt)
ES (1) ES2278444T3 (pt)
GB (2) GB9810464D0 (pt)
HU (1) HUP0102290A3 (pt)
IL (2) IL139059A0 (pt)
NO (1) NO20005782L (pt)
NZ (1) NZ507560A (pt)
PL (1) PL344438A1 (pt)
PT (1) PT1079819E (pt)
TR (1) TR200003376T2 (pt)
WO (1) WO1999059568A1 (pt)
ZA (1) ZA200006131B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU749699B2 (en) * 1998-02-07 2002-07-04 British Biotech Pharmaceuticals Limited Antibacterial agents
GB9810464D0 (en) * 1998-05-16 1998-07-15 British Biotech Pharm Hydroxamic acid derivatives
US6908911B1 (en) * 1999-08-10 2005-06-21 British Biotech Pharmaceuticals Limited Antibacterial agents
WO2001040198A2 (fr) * 1999-11-30 2001-06-07 Aventis Pharma S.A. Derives macrocycliques de l'acide hydroxamique et leur utilisation en tant qu'antimicrobiens
FR2801591B1 (fr) * 1999-11-30 2002-03-01 Aventis Pharma Sa Derives macrocycliques de l'acide hydroxamique, leur preparation et les compositions qui les contiennent
GB9929979D0 (en) * 1999-12-17 2000-02-09 Darwin Discovery Ltd Hydroxamic acid derivatives
WO2001044179A1 (en) * 1999-12-17 2001-06-21 Versicor, Inc. Novel succinate compounds, compositions and methods of use and preparation
AU2002230385A1 (en) * 2000-09-25 2002-04-15 Questcor Pharmaceuticals, Inc. Peptide deformylase inhibitors
AU2002212541A1 (en) 2000-11-23 2002-06-03 British Biotech Pharmaceuticals Ltd Ydroxamic acid or n-formyl hydroxylamine derivatives as inhibitors of bakterial polypeptide deformylase for treating microbial infections
EP1372692A4 (en) * 2001-03-19 2005-10-26 Sloan Kettering Inst Cancer ASYMMETRIC SYNTHESIS OF (S, S, R) - (-) - ACTINONE AND ITS ANALOG AND USES THEREOF
US20040267015A1 (en) * 2001-04-05 2004-12-30 Ajita Bhat Peptide deformylase inhibitors
GB0128943D0 (en) * 2001-12-04 2002-01-23 Novo Pharmaceuticals De Ltd Bacterial enzyme inhibitors
JP4190862B2 (ja) * 2001-12-18 2008-12-03 シャープ株式会社 表示装置およびその駆動方法
GB0208579D0 (en) * 2002-04-13 2002-05-22 British Biotech Pharm Antibacterial agents
DE10320453A1 (de) * 2003-05-08 2004-11-25 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Bioisostere von Actinonin
EP2224973B1 (en) * 2007-11-29 2016-04-20 Inolex Investment Corporation Preservatives for cosmetic, toiletry and pharmaceutical compositions
DE102011088962A1 (de) * 2011-12-19 2013-06-20 Beiersdorf Ag Wirkstoffkombinationen aus einer oder mehreren Carbonsäuren, insbesondereHydroxycarbonsäuren, und einer oder mehreren physiologisch unbedenklichen Hydroxamsäure sowie kosmetische oder dermatologische Zubereitungen, solcheWirkstoffkombinationen enthaltend
US10829440B2 (en) 2015-06-12 2020-11-10 Brown University Antibacterial compounds and methods of making and using same
WO2019005064A1 (en) * 2017-06-29 2019-01-03 Kimberly-Clark Worldwide, Inc. ANTIMICROBIAL COMPOSITION COMPRISING DIHYDROXAMIC ACID AND METHODS OF INHIBITING MICROBIAL PROLIFERATION USING THE SAME
CN108672095A (zh) * 2018-05-04 2018-10-19 广东省资源综合利用研究所 γ-羟基烷基羟肟酸及其制备方法与应用
US11555010B2 (en) 2019-07-25 2023-01-17 Brown University Diamide antimicrobial agents

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1028921A (en) 1962-01-23 1966-05-11 Ranjeet Bhagwan Singh New antibiotic
US4303662A (en) * 1980-11-24 1981-12-01 E. R. Squibb & Sons, Inc. Carboxyacyl, mercapto and acylmercapto derivatives of heterobicyclo compounds
JPH0670019B2 (ja) 1989-07-21 1994-09-07 明治製菓株式会社 新抗生物質ｓｆ２１９７ｃ物質およびその製造法
GB8919251D0 (en) * 1989-08-24 1989-10-04 British Bio Technology Compounds
JPH03157372A (ja) 1989-11-13 1991-07-05 Yamanouchi Pharmaceut Co Ltd Ｙｌ―０１８６９ｐ物質及びその製造法
AU2228292A (en) 1991-06-14 1993-01-12 Research Corporation Technologies, Inc. Peptide derivatives of collagenase inhibitor
GB9223904D0 (en) * 1992-11-13 1993-01-06 British Bio Technology Inhibition of cytokine production
JPH09503201A (ja) * 1993-08-23 1997-03-31 イミュネックス・コーポレーション Ｔｎｆ−アルファ分泌の阻害剤
JP3157372B2 (ja) 1993-11-29 2001-04-16 三洋電機株式会社 フィルタ
CA2193691A1 (en) * 1994-06-22 1995-12-28 Andrew Miller Metalloproteinase inhibitors
US5532265A (en) * 1994-11-30 1996-07-02 The Board Of Trustees Of The Leland Stanford Junior University Treatment of central nervous system inflammatory disease with matrix metalloprotease inhibitors
GB9507799D0 (en) * 1995-04-18 1995-05-31 British Biotech Pharm Metalloproteinase inhibitors
US6281245B1 (en) * 1996-10-28 2001-08-28 Versicor, Inc. Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof
AU5187698A (en) 1996-12-06 1998-06-29 Cancerforskningsfondet Af 1989 Inhibition of invasive remodelling
ZA9711121B (en) * 1996-12-13 1998-06-23 Handelman Joseph H Reduction of hair growth.
AU749699B2 (en) * 1998-02-07 2002-07-04 British Biotech Pharmaceuticals Limited Antibacterial agents
GB9810464D0 (en) * 1998-05-16 1998-07-15 British Biotech Pharm Hydroxamic acid derivatives

Also Published As

Publication number Publication date
US7323563B2 (en) 2008-01-29
PT1079819E (pt) 2007-03-30
KR20010034861A (ko) 2001-04-25
EP1079819A1 (en) 2001-03-07
TR200003376T2 (tr) 2001-03-21
IL139059A (en) 2006-12-31
WO1999059568A1 (en) 1999-11-25
IL139059A0 (en) 2001-11-25
HUP0102290A2 (hu) 2001-11-28
DE69934309T2 (de) 2007-07-05
KR100634089B1 (ko) 2006-10-17
CN1300210A (zh) 2001-06-20
CA2332713C (en) 2008-04-01
HUP0102290A3 (en) 2001-12-28
DE69934309D1 (de) 2007-01-18
GB2353708A (en) 2001-03-07
NZ507560A (en) 2003-06-30
ES2278444T3 (es) 2007-08-01
AU3942199A (en) 1999-12-06
BR9910488A (pt) 2001-01-09
EP1754477A3 (en) 2007-03-14
CY1106452T1 (el) 2011-10-12
ATE347356T1 (de) 2006-12-15
AU754063B2 (en) 2002-10-31
ZA200006131B (en) 2002-01-30
DK1079819T3 (da) 2007-04-10
CA2332713A1 (en) 1999-11-25
US20020198241A1 (en) 2002-12-26
EP1754477A2 (en) 2007-02-21
US6441042B1 (en) 2002-08-27
PL344438A1 (en) 2001-11-05
GB0024789D0 (en) 2000-11-22
US6992190B2 (en) 2006-01-31
JP2002515427A (ja) 2002-05-28
EP1079819B1 (en) 2006-12-06
GB9810464D0 (en) 1998-07-15
US20060211732A1 (en) 2006-09-21
NO20005782D0 (no) 2000-11-15

Similar Documents

Publication Publication Date Title
NO20005782L (no) Hydroksaminsyrederivater som antibakterielle midler
GB2349884A (en) Antibacterial agents
NO20002173D0 (no) Pleuromutilin-derivater som antimikrobielle midler
BR0012615A (pt) Amidas aromáticas heterocìclicas fungicidas e suas composições, métodos de uso e preparação
BR9809531A (pt) Composições herbicidas.
DK0920421T3 (da) Isoxazolinderivater anvendelige som antimikrobielle midler
NO20002217D0 (no) Cyclopentan-heptansyre, 2-heteroarylalkenylderivater som terapeutiske midler
DK0869949T3 (da) Benzoxaziner som antimikrobielle midler
ES2110673T3 (es) N-azinil-n'-(het)arilsulfonil-ureas como herbicidas.
HRP20040806B1 (hr) Herbicidne kombinacije s aciliranim aminofenilsulfonil-ureama
BRPI0413266A (pt) formulações herbicidas de glifosato de alta potência e baixa viscosidade
ATE255554T1 (de) Cyclopentenonderivate
BR0014702A (pt) Composição de glifosato herbicida, e, método de formação de uma composição de glifosato para a aplicação a ervas daninhas
PT1316254E (pt) Composicao de pesticida e metodo para controlar pragas
BR9807330A (pt) Agentes inibidores do progresso de pterìgio e recorrência pós-operatória do mesmo
DE69825977D1 (de) Antivirale mittel
ATE205835T1 (de) Akarizid und insektizid wirksame, substituierte pyrimidine und verfahren zu ihrer herstellung
DK0937708T3 (da) Sulfonamidderivater
DE69912639D1 (de) N-formyl hydroxylamin derivate als antibakterielle mittel
DE60006053D1 (de) 2-Aryloxy-4-methyl-6-pyrazol-1-yl-pyridine wirksam als Herbizide
BR9901206A (pt) Derivados de pirimidinona.
FI921475A0 (fi) 1,4-dihydro-4-oxo-3-kinolinderivat som selektivt toxiska antibakteriella aemenn hos daeggdjur.
HUP9902191A2 (hu) Az érképződést gátló anyag
CO4650115A1 (es) Nuevos derivados del acido hidroximico para uso en la pro- teccion de las plantas

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application