NO174048C - Makrocykliske forbindelser og diagnostiske midler inneholdende disse - Google Patents

Makrocykliske forbindelser og diagnostiske midler inneholdende disse

Info

Publication number
NO174048C
NO174048C NO873132A NO873132A NO174048C NO 174048 C NO174048 C NO 174048C NO 873132 A NO873132 A NO 873132A NO 873132 A NO873132 A NO 873132A NO 174048 C NO174048 C NO 174048C
Authority
NO
Norway
Prior art keywords
carbon atoms
groups
group
chain
straight
Prior art date
Application number
NO873132A
Other languages
English (en)
Other versions
NO873132D0 (no
NO873132L (no
NO174048B (no
Inventor
Heinz Gries
Bernd Raduchel
Ulrich Speck
Hans-Joachim Weinmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO873132D0 publication Critical patent/NO873132D0/no
Publication of NO873132L publication Critical patent/NO873132L/no
Publication of NO174048B publication Critical patent/NO174048B/no
Publication of NO174048C publication Critical patent/NO174048C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic System without C-Metal linkages
NO873132A 1986-07-28 1987-07-27 Makrocykliske forbindelser og diagnostiske midler inneholdende disse NO174048C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3625417A DE3625417C2 (de) 1986-07-28 1986-07-28 Tetraazacyclododecan-Derivate

Publications (4)

Publication Number Publication Date
NO873132D0 NO873132D0 (no) 1987-07-27
NO873132L NO873132L (no) 1988-01-29
NO174048B NO174048B (no) 1993-11-29
NO174048C true NO174048C (no) 1994-03-09

Family

ID=6306101

Family Applications (1)

Application Number Title Priority Date Filing Date
NO873132A NO174048C (no) 1986-07-28 1987-07-27 Makrocykliske forbindelser og diagnostiske midler inneholdende disse

Country Status (13)

Country Link
EP (1) EP0255471B1 (no)
JP (1) JPH0753720B2 (no)
AT (1) ATE80391T1 (no)
CA (1) CA1341176C (no)
DE (2) DE3625417C2 (no)
DK (1) DK171574B1 (no)
ES (1) ES2052599T3 (no)
GR (1) GR3005808T3 (no)
IE (1) IE60677B1 (no)
NO (1) NO174048C (no)
NZ (1) NZ221225A (no)
PT (1) PT85410B (no)
ZA (1) ZA875561B (no)

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EP0416033B1 (en) * 1988-05-25 1996-03-06 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Macrocyclic chelates and methods of use thereof
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DE4237943C2 (de) * 1992-11-06 1997-10-23 Schering Ag Verfahren zur Herstellung von Metallkomplexen der N-beta-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecan- und N-beta-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivate
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US5310535A (en) * 1992-04-24 1994-05-10 The Dow Chemical Company Carboxamide modified polyamine chelators and radioactive complexes thereof for conjugation to antibodies
DE4218744C2 (de) * 1992-06-04 1997-11-06 Schering Ag Verfahren zur Herstellung von N-ß-Hxdroxyalkyl-tri-N-carboxylalkyl-1,4,7,10-tetraazacyclododecan- und N-ß-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivaten und deren Metallkomplexe
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CA2371728C (en) 1999-06-11 2009-06-02 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
WO2001028982A1 (fr) * 1999-10-22 2001-04-26 Mitsubishi Pharma Corporation Derives d'acide diethylenetriaminepenta acetique
FR2802928B1 (fr) * 1999-12-22 2003-01-31 Air Liquide Polyazacycloalcanes eventuellement greffes sur une matrice solide, complexes organometalliques les incorporant comme ligands. utilisation desdits composes a l'extraction de metaux lourds
WO2006124726A2 (en) 2005-05-12 2006-11-23 The General Hospital Corporation Novel biotinylated compositions
DE102007002726A1 (de) 2007-01-18 2008-07-31 Bayer Schering Pharma Aktiengesellschaft Neue Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
US10556873B2 (en) 2008-02-22 2020-02-11 Illinois Institute Of Technology Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using
WO2010011367A2 (en) * 2008-02-22 2010-01-28 Illinois Institute Of Technology Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using
US10189803B2 (en) 2008-02-22 2019-01-29 Illinois Institute Of Technology Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
US9446995B2 (en) 2012-05-21 2016-09-20 Illinois Institute Of Technology Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
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WO2011054480A1 (de) 2009-11-09 2011-05-12 Bayer Schering Pharma Aktiengesellschaft Gadobutrolherstellung mittels keramischer membran
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SI3386954T1 (sl) * 2015-12-10 2021-02-26 Bracco Imaging Spa Dimerna kontrastna sredstva
CN109803958B (zh) 2016-09-27 2023-10-31 拜耳制药股份公司 生产考布曲钙的变型a的晶型的方法
CN110035996B (zh) 2016-11-28 2022-08-09 拜耳医药股份公司 用于磁共振成像的新型高弛豫性钆螯合物
JP7145156B2 (ja) * 2016-12-12 2022-09-30 ブラッコ・イメージング・ソシエタ・ペル・アチオニ 二量体造影剤
CN108358954B (zh) * 2018-01-17 2019-10-29 南开大学 一种手性稀土-氮氧自由基单链磁体及其制备方法
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CN110357828B (zh) * 2019-08-13 2021-03-19 牡丹江医学院 一种核磁共振造影剂及其制备方法和用途

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NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
DE3316703A1 (de) * 1983-05-04 1984-11-08 Schering AG, 1000 Berlin und 4709 Bergkamen Orales kontrastmittel fuer die kernspintomographie und dessen herstellung
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Also Published As

Publication number Publication date
JPS6341468A (ja) 1988-02-22
NO873132D0 (no) 1987-07-27
EP0255471A1 (de) 1988-02-03
GR3005808T3 (no) 1993-06-07
DE3625417A1 (de) 1988-02-11
DE3781620D1 (de) 1992-10-15
DE3625417C2 (de) 1998-10-08
DK171574B1 (da) 1997-01-20
NZ221225A (en) 1990-09-26
DK393387D0 (da) 1987-07-28
ATE80391T1 (de) 1992-09-15
AU7621787A (en) 1988-02-04
IE872038L (en) 1988-01-28
DK393387A (da) 1988-01-29
CA1341176C (en) 2001-01-30
ES2052599T3 (es) 1994-07-16
JPH0753720B2 (ja) 1995-06-07
EP0255471B1 (de) 1992-09-09
IE60677B1 (en) 1994-08-10
ZA875561B (en) 1989-03-29
PT85410B (pt) 1990-06-29
PT85410A (de) 1987-08-01
AU604249B2 (en) 1990-12-13
NO873132L (no) 1988-01-29
NO174048B (no) 1993-11-29

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