NO160369C - Analogifremgangsmaate for fremstilling av nye, terapeutiskaktive 1,3-dihydro-6-(1-hydroksy-2-dimetylaminometyl-allyl)-7-hydroksy-furo(3,4-c)-pyridinderivater. - Google Patents

Analogifremgangsmaate for fremstilling av nye, terapeutiskaktive 1,3-dihydro-6-(1-hydroksy-2-dimetylaminometyl-allyl)-7-hydroksy-furo(3,4-c)-pyridinderivater.

Info

Publication number
NO160369C
NO160369C NO850399A NO850399A NO160369C NO 160369 C NO160369 C NO 160369C NO 850399 A NO850399 A NO 850399A NO 850399 A NO850399 A NO 850399A NO 160369 C NO160369 C NO 160369C
Authority
NO
Norway
Prior art keywords
hydroxy
furo
dimethylaminomethyl
dihydro
allyl
Prior art date
Application number
NO850399A
Other languages
English (en)
Norwegian (no)
Other versions
NO160369B (no
NO850399L (no
Inventor
Andre Esanu
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of NO850399L publication Critical patent/NO850399L/no
Publication of NO160369B publication Critical patent/NO160369B/no
Publication of NO160369C publication Critical patent/NO160369C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
NO850399A 1984-02-02 1985-02-01 Analogifremgangsmaate for fremstilling av nye, terapeutiskaktive 1,3-dihydro-6-(1-hydroksy-2-dimetylaminometyl-allyl)-7-hydroksy-furo(3,4-c)-pyridinderivater. NO160369C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848402740A GB8402740D0 (en) 1984-02-02 1984-02-02 Furo-(3 4-c)-pyridine derivatives

Publications (3)

Publication Number Publication Date
NO850399L NO850399L (no) 1985-08-05
NO160369B NO160369B (no) 1989-01-02
NO160369C true NO160369C (no) 1989-04-12

Family

ID=10555953

Family Applications (1)

Application Number Title Priority Date Filing Date
NO850399A NO160369C (no) 1984-02-02 1985-02-01 Analogifremgangsmaate for fremstilling av nye, terapeutiskaktive 1,3-dihydro-6-(1-hydroksy-2-dimetylaminometyl-allyl)-7-hydroksy-furo(3,4-c)-pyridinderivater.

Country Status (24)

Country Link
US (1) US4581362A (sv)
JP (1) JPS60181088A (sv)
AT (1) AT391700B (sv)
BE (1) BE901545A (sv)
CA (1) CA1300148C (sv)
CH (1) CH663023A5 (sv)
DE (1) DE3503435A1 (sv)
DK (1) DK158951C (sv)
DZ (1) DZ743A1 (sv)
ES (1) ES8607308A1 (sv)
FI (1) FI82051C (sv)
FR (2) FR2559062B1 (sv)
GB (1) GB8402740D0 (sv)
HK (1) HK92587A (sv)
IE (1) IE58229B1 (sv)
IT (1) IT1200587B (sv)
LU (1) LU85744A1 (sv)
MA (1) MA20342A1 (sv)
NL (1) NL8500241A (sv)
NO (1) NO160369C (sv)
OA (1) OA07947A (sv)
PT (1) PT79913B (sv)
SE (2) SE8500460L (sv)
ZA (1) ZA85508B (sv)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8907480D0 (en) * 1989-04-03 1989-05-17 Scaras Societe De Conseils De Separation of insomers of furo(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
JPH054664A (ja) * 1991-06-21 1993-01-14 Yoozuri:Kk 運搬等用の包装体及び包装方法
PE20221914A1 (es) 2011-12-28 2022-12-23 Global Blood Therapeutics Inc Compuestos de benzaldehido sustituidos y metodos para su uso en incrementar la oxigenacion del tejido
EP2797597B1 (en) 2011-12-28 2020-02-26 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
WO2014145040A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
MY191087A (en) 2013-03-15 2022-05-30 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
AU2014237348C1 (en) 2013-03-15 2019-02-07 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
PE20160078A1 (es) 2013-03-15 2016-03-02 Global Blood Therapeutics Inc Compuestos y sus usos para modular la hemoglobina
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
EA202092627A1 (ru) 2013-11-18 2021-09-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
CN105431147A (zh) 2014-02-07 2016-03-23 全球血液疗法股份有限公司 2-羟基-6-((2-(1-异丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)苯甲醛的游离碱的结晶多晶型物
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
WO2017096230A1 (en) 2015-12-04 2017-06-08 Global Blood Therapeutics, Inc. Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
TWI825524B (zh) 2016-05-12 2023-12-11 美商全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
EP3860975B1 (en) 2018-10-01 2023-10-18 Global Blood Therapeutics, Inc. Modulators of hemoglobin for the treatment of sickle cell disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786269B (en) * 1977-11-25 1979-10-31 Scras New pyridine derivative,its preparation and use
IN156817B (sv) * 1981-02-10 1985-11-09 Scras
GB8330517D0 (en) * 1983-11-16 1983-12-21 Scras 6-vinyl-furo-(3,4-c)pyridine derivatives
GB8330658D0 (en) * 1983-11-17 1983-12-29 Scras 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives

Also Published As

Publication number Publication date
CH663023A5 (fr) 1987-11-13
FI850275A0 (fi) 1985-01-22
GB8402740D0 (en) 1984-03-07
FI82051C (sv) 1991-01-10
PT79913B (en) 1986-11-10
FR2559152B1 (fr) 1987-05-22
SE8500460D0 (sv) 1985-02-01
JPH0240069B2 (sv) 1990-09-10
DK45585A (da) 1985-08-03
IE58229B1 (en) 1993-08-11
LU85744A1 (fr) 1985-07-24
DE3503435A1 (de) 1985-08-08
US4581362A (en) 1986-04-08
FR2559062B1 (fr) 1987-05-22
MA20342A1 (fr) 1985-10-01
ATA27585A (de) 1990-05-15
PT79913A (en) 1985-03-01
AT391700B (de) 1990-11-12
ES8607308A1 (es) 1986-05-16
FI850275L (fi) 1985-08-03
OA07947A (fr) 1987-01-31
BE901545A (fr) 1985-07-22
FR2559152A1 (fr) 1985-08-09
SE8500460L (sv) 1985-08-03
DK158951C (da) 1990-12-31
NO160369B (no) 1989-01-02
DE3503435C2 (sv) 1991-11-07
HK92587A (en) 1987-12-11
IT1200587B (it) 1989-01-27
FR2559062A1 (fr) 1985-08-09
ZA85508B (en) 1985-11-27
SE460903B (sv) 1989-12-04
JPS60181088A (ja) 1985-09-14
IE850241L (en) 1985-08-02
DK158951B (da) 1990-08-06
CA1300148C (en) 1992-05-05
DZ743A1 (fr) 2004-09-13
NO850399L (no) 1985-08-05
IT8519327A0 (it) 1985-02-01
DK45585D0 (da) 1985-02-01
NL8500241A (nl) 1985-09-02
FI82051B (fi) 1990-09-28
ES540080A0 (es) 1986-05-16

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