NO142402C - Analogifremgangsmaate for fremstilling av farmakologisk aktive benzimidazoler - Google Patents

Analogifremgangsmaate for fremstilling av farmakologisk aktive benzimidazoler

Info

Publication number
NO142402C
NO142402C NO752022A NO752022A NO142402C NO 142402 C NO142402 C NO 142402C NO 752022 A NO752022 A NO 752022A NO 752022 A NO752022 A NO 752022A NO 142402 C NO142402 C NO 142402C
Authority
NO
Norway
Prior art keywords
preparation
pharmacologically active
analogy procedure
benzimidazoles
active benzimidazoles
Prior art date
Application number
NO752022A
Other languages
English (en)
Norwegian (no)
Other versions
NO752022L (xx
NO142402B (no
Inventor
Volkhard Austel
Eberhard Kutter
Joachim Heider
Wolfgang Eberlein
Rudolf Kadatz
Willi Diederen
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742427943 external-priority patent/DE2427943C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO752022L publication Critical patent/NO752022L/no
Publication of NO142402B publication Critical patent/NO142402B/no
Publication of NO142402C publication Critical patent/NO142402C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO752022A 1974-06-10 1975-06-09 Analogifremgangsmaate for fremstilling av farmakologisk aktive benzimidazoler NO142402C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742427943 DE2427943C2 (de) 1974-06-10 1974-06-10 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2516040A DE2516040C2 (de) 1974-06-10 1975-04-12 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (3)

Publication Number Publication Date
NO752022L NO752022L (xx) 1975-12-11
NO142402B NO142402B (no) 1980-05-05
NO142402C true NO142402C (no) 1980-08-13

Family

ID=25767253

Family Applications (1)

Application Number Title Priority Date Filing Date
NO752022A NO142402C (no) 1974-06-10 1975-06-09 Analogifremgangsmaate for fremstilling av farmakologisk aktive benzimidazoler

Country Status (23)

Country Link
US (1) US4026891A (xx)
JP (1) JPS6015632B2 (xx)
AT (1) AT342610B (xx)
BE (1) BE830030A (xx)
BG (2) BG23216A3 (xx)
CA (1) CA1041095A (xx)
CH (1) CH620438A5 (xx)
CS (1) CS195292B2 (xx)
DD (1) DD120440A5 (xx)
DE (1) DE2516040C2 (xx)
DK (1) DK258975A (xx)
ES (2) ES437296A1 (xx)
FI (1) FI59408C (xx)
FR (1) FR2273545A1 (xx)
GB (1) GB1466547A (xx)
HU (1) HU171059B (xx)
IE (1) IE41257B1 (xx)
IL (1) IL47445A (xx)
NL (1) NL178969C (xx)
NO (1) NO142402C (xx)
PH (1) PH14298A (xx)
RO (1) RO68750A (xx)
SE (1) SE420836B (xx)

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JPS53117215A (en) * 1977-03-24 1978-10-13 Hideyoshi Morita Earthquakeeproof steel beam
ES482789A0 (es) * 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
US4258185A (en) * 1978-10-17 1981-03-24 Yoshitomi Pharmaceutical Industries, Ltd. Pyridazinone compounds
DE2935359A1 (de) * 1979-09-01 1981-03-26 Basf Ag, 67063 Ludwigshafen 6-imidazolyl-3-hydrazino-pyridazine
DE3006671A1 (de) * 1980-02-22 1981-08-27 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzoxazole, deren herstellung und deren verwendung als arzneumittel
DE3129447A1 (de) * 1981-07-25 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benztriazole, ihre herstellung und ihre verwendung als arzneimittel"
US4699909A (en) * 1981-07-25 1987-10-13 Dr. Karl Thomae Gmbh Benzotriazolyl-4,5-dihydro-3(2H)-pyridazinones
ZA859091B (en) * 1984-12-24 1987-07-29 Warner Lambert Co Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents
US4840955A (en) * 1984-12-24 1989-06-20 Warner-Lambert Company 6-substituted-2(1H)-quinolinones and related compounds having use as cardiotonic, antihypertensive, and antithrombotic agents
US4725686A (en) * 1985-11-22 1988-02-16 William H. Rorer, Inc. Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US4906630A (en) * 1985-11-22 1990-03-06 Rorer Pharmaceutical Corporation Method of increasing cardiac contractility using pharmaceutical compositions comprising benzodiazinone- pyridazinone or hydroxy-pyrazolyl compounds
US4785101A (en) * 1985-11-22 1988-11-15 Rorer Pharmaceutical Corporation Benzodiazinone-hydroxypyrazolyl compounds, cardiotonic compositions including the same and their uses
US4868300A (en) * 1985-11-22 1989-09-19 Rorer Pharmaceutical Corporation Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
JPS62249018A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
JPS62249019A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
US5002944A (en) * 1986-10-29 1991-03-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having cardiotonic activity
US4859672A (en) * 1986-10-29 1989-08-22 Rorer Pharmaceutical Corporation Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone
JPS63181827U (xx) * 1987-05-13 1988-11-24
DE4237656A1 (de) * 1992-06-13 1993-12-16 Merck Patent Gmbh Benzimidazolderivate
US6465484B1 (en) 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
US6162804A (en) * 1997-09-26 2000-12-19 Merck & Co., Inc. Tyrosine kinase inhibitors
KR100515918B1 (ko) * 1998-10-23 2005-09-20 토레이가부시끼가이샤 면역 조절용 약학 조성물
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
US20030236259A1 (en) * 2002-02-05 2003-12-25 Rolf Hohlweg Novel aryl- and heteroarylpiperazines
AR051090A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
AU2005286790A1 (en) * 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Bicyclic heterocyclic derivatives and their use as inhibitors of stearoyl-CoA-desaturase (SCD)
CN101083994A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其用作硬脂酰CoA去饱和酶抑制剂的用途
CN101083992A (zh) 2004-09-20 2007-12-05 泽农医药公司 抑制人硬脂酰CoA去饱和酶的哒嗪衍生物
EP1799668A1 (en) 2004-09-20 2007-06-27 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase
BRPI0515482A (pt) * 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos e seus usos como agentes terapêuticos
AR051202A1 (es) * 2004-09-20 2006-12-27 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
AU2005286793A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-CoA desaturase enzymes
JP4714921B2 (ja) * 2005-02-14 2011-07-06 トーアエイヨー株式会社 ピモベンダンの製造法及びその中間体
EP2029138A1 (en) * 2005-06-03 2009-03-04 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
BRPI0613564A2 (pt) 2005-07-04 2011-01-18 Novo Nordisk As compostos, seus usos na preparação de composições farmacêuticas e composições farmacêuticas compreendendo os mesmos
MX2008002166A (es) * 2005-08-15 2008-04-22 Irm Llc Compuestos y composiciones como mimeticos de trombopoietina (tpo).
AU2007267197B2 (en) * 2006-05-29 2011-12-01 High Point Pharmaceuticals, Llc 3- (1, 3-Benzodioxol-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine H3 receptor antagonist
EP2014656A3 (en) * 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC New heteocyclic h3 antagonists
WO2010107768A1 (en) * 2009-03-18 2010-09-23 Schering Corporation Bicyclic compounds as inhibitors of diacylglycerol acyltransferase
US8729263B2 (en) 2012-08-13 2014-05-20 Novartis Ag 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions
EA030631B1 (ru) * 2013-07-31 2018-09-28 Новартис Аг 1,4-дизамещенные аналоги пиридазинхинолина и способы лечения состояний, связанных с smn-дефицитом
WO2018086703A1 (en) * 2016-11-11 2018-05-17 Bayer Pharma Aktiengesellschaft Dihydropyridazinones substituted with phenylureas

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Publication number Priority date Publication date Assignee Title
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
US3705157A (en) * 1970-10-19 1972-12-05 American Cyanamid Co Azolylpyridazine compounds and quaternary salts thereof
US3935209A (en) * 1973-03-12 1976-01-27 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles

Also Published As

Publication number Publication date
JPS516980A (xx) 1976-01-20
JPS6015632B2 (ja) 1985-04-20
AU8192675A (en) 1976-12-16
FI59408C (fi) 1981-08-10
DD120440A5 (xx) 1976-06-12
BG23216A3 (bg) 1977-07-12
AT342610B (de) 1978-04-10
BE830030A (fr) 1975-12-09
FI59408B (fi) 1981-04-30
DK258975A (da) 1975-12-11
DE2516040A1 (de) 1976-11-04
HU171059B (hu) 1977-10-28
PH14298A (en) 1981-05-19
FR2273545A1 (fr) 1976-01-02
NL7506806A (nl) 1975-12-12
SE7506583L (sv) 1975-12-11
ATA344575A (de) 1977-08-15
IE41257B1 (en) 1979-11-21
IE41257L (en) 1975-12-10
BG24052A3 (en) 1977-12-15
CS195292B2 (en) 1980-01-31
DE2516040C2 (de) 1984-12-20
US4026891A (en) 1977-05-31
IL47445A (en) 1978-07-31
CH620438A5 (xx) 1980-11-28
IL47445A0 (en) 1975-08-31
RO68750A (ro) 1980-03-15
CA1041095A (en) 1978-10-24
FI751700A (xx) 1975-12-11
FR2273545B1 (xx) 1979-08-10
NO752022L (xx) 1975-12-11
NO142402B (no) 1980-05-05
ES437296A1 (es) 1977-01-01
NL178969C (nl) 1986-06-16
SE420836B (sv) 1981-11-02
ES441340A1 (es) 1977-03-16
GB1466547A (en) 1977-03-09

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