NL7116577A - - Google Patents

Info

Publication number
NL7116577A
NL7116577A NL7116577A NL7116577A NL7116577A NL 7116577 A NL7116577 A NL 7116577A NL 7116577 A NL7116577 A NL 7116577A NL 7116577 A NL7116577 A NL 7116577A NL 7116577 A NL7116577 A NL 7116577A
Authority
NL
Netherlands
Application number
NL7116577A
Other versions
NL172744B (nl
NL172744C (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7116577A publication Critical patent/NL7116577A/xx
Publication of NL172744B publication Critical patent/NL172744B/xx
Application granted granted Critical
Publication of NL172744C publication Critical patent/NL172744C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL7116577A 1970-12-05 1971-12-02 Werkwijze voor het bereiden van basisch gesubstitueerde fenylacetonitrile-verbindingen en deze verbindingen bevattende geneesmiddelen met een de coronaire doorstroming bevorderende activiteit. NL172744C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702059923 DE2059923C3 (de) 1970-12-05 1970-12-05 l-a-Isopropyl-o-[(N-methyl-N-homoveratryl)v-aminopropyl] -3,4-dimethoxyphenylacetonitril, Verfahren zu dessen Herstellung und dieses enthaltende Arzneimittel

Publications (3)

Publication Number Publication Date
NL7116577A true NL7116577A (en:Method) 1972-06-07
NL172744B NL172744B (nl) 1983-05-16
NL172744C NL172744C (nl) 1983-10-17

Family

ID=5790091

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7116577A NL172744C (nl) 1970-12-05 1971-12-02 Werkwijze voor het bereiden van basisch gesubstitueerde fenylacetonitrile-verbindingen en deze verbindingen bevattende geneesmiddelen met een de coronaire doorstroming bevorderende activiteit.

Country Status (8)

Country Link
AT (1) AT305262B (en:Method)
BE (1) BE776218A (en:Method)
CH (1) CH565748A5 (en:Method)
DE (1) DE2059923C3 (en:Method)
FR (1) FR2116564B1 (en:Method)
GB (1) GB1367677A (en:Method)
NL (1) NL172744C (en:Method)
YU (2) YU35346B (en:Method)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2946545A1 (de) 1979-11-17 1981-05-27 Basf Ag, 6700 Ludwigshafen Verfahren zur gewinnung der enantiomeren formen von 4-cyan-1-(n-methyl-n-(2'-((3'',4'',-dimethoxyphenyl))-aethyl)-amino)-5-methyl-4-(3',4',5'-trimethoxyphenyl)-hexan und dessen salzen
DE3034221A1 (de) 1980-09-11 1982-04-22 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung basisch substituierter phenylacetonitrile
DE3144150A1 (de) 1981-04-10 1982-12-09 Basf Ag, 6700 Ludwigshafen (omega)-cyan-1,(omega)-diphenyl-azaalkan-derivate, ihre herstellung und diese enthaltende arzneimittel
DE3138488A1 (de) * 1981-09-28 1983-04-14 Knoll Ag, 6700 Ludwigshafen Verwendung von basisch substituierten phenylacetonritrilen bei der vorbeugenden bekaempfung von krankheiten und mittel dafuer
DE3344755A1 (de) * 1983-12-10 1985-06-20 Basf Ag, 6700 Ludwigshafen 1,7-diphenyl-3-methylaza-7-cyan-8-methyl-nonan zur verwendung bei der bekaempfung von krankheiten
DE3635930A1 (de) * 1986-10-22 1988-04-28 Basf Ag Wirkstoffe zur anwendung bei der behandlung von tumoren
DE3603660C2 (de) * 1986-02-06 1994-09-15 Fresenius Ag Verbesserte Peritonealdialyse
DE4203547A1 (de) * 1992-02-07 1993-08-12 Knoll Ag Verfahren zur racemattrennung von verapamil
GB9319918D0 (en) * 1993-09-27 1993-11-10 Chiros Ltd Chiral compounds and their preparation
US5910601A (en) * 1994-09-26 1999-06-08 Darwin Discovery Limited Chiral nitriles, their preparation and their use for the manufacture of verapamil and analogues
ATE198881T1 (de) * 1996-02-08 2001-02-15 Darwin Discovery Ltd Trennung von 4-cyano-4-(3,4-dimethoxyphenyl)-5- methylexancarbonsäure
US5892093A (en) * 1996-02-08 1999-04-06 Darwin Discovery Limited Resolution
AU3205497A (en) * 1996-05-23 1997-12-09 G.D. Searle & Co. Pharmaceutical compositions containing non-racemic verapamil and process for optimizing the pharmaceutical activity of r- and s-verapamil
US5859279A (en) * 1996-09-10 1999-01-12 Darwin Discovery Limited Compound and process
GB9618835D0 (en) * 1996-09-10 1996-10-23 Chiroscience Ltd Process
EP1167348A4 (en) * 1999-03-16 2002-11-13 Eisai Co Ltd nitrile
US6884791B2 (en) 1999-07-06 2005-04-26 Methylgene, Inc. Inhibitors of β-lactamase
DE60024455T2 (de) 1999-07-06 2006-08-03 Methylgene, Inc., Saint-Laurent Sulfonamidomethylphosphonat-BETA-LACTAMASE-Inhibitoren
BRPI0812919B8 (pt) 2007-06-20 2021-05-25 Milestone Pharmaceuticals Inc composição farmacêutica que compreende um composto e kit
WO2016181292A1 (en) 2015-05-12 2016-11-17 Piramal Enterprises Limited A process for the preparation of verapamil hydrochloride

Also Published As

Publication number Publication date
YU35346B (en) 1980-12-31
NL172744B (nl) 1983-05-16
NL172744C (nl) 1983-10-17
DE2059923A1 (de) 1972-06-15
CH565748A5 (en:Method) 1975-08-29
YU35348B (en) 1980-12-31
FR2116564B1 (en:Method) 1975-03-14
YU21879A (en) 1980-06-30
DE2059923C3 (de) 1979-01-25
DE2059923B2 (de) 1978-05-18
FR2116564A1 (en:Method) 1972-07-13
YU302371A (en) 1980-06-30
GB1367677A (en) 1974-09-18
BE776218A (fr) 1972-06-05
AT305262B (de) 1973-02-26

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Legal Events

Date Code Title Description
BB A search report has been drawn up
BC A request for examination has been filed
V4 Lapsed because of reaching the maxim lifetime of a patent