NL227699A - Werkwijze ter bereiding van trifluormethylfenothiazinen met therapeutische werking en zuuradditiezouten daarvan - Google Patents

Werkwijze ter bereiding van trifluormethylfenothiazinen met therapeutische werking en zuuradditiezouten daarvan

Info

Publication number
NL227699A
NL227699A NL227699A NL227699A NL227699A NL 227699 A NL227699 A NL 227699A NL 227699 A NL227699 A NL 227699A NL 227699 A NL227699 A NL 227699A NL 227699 A NL227699 A NL 227699A
Authority
NL
Netherlands
Prior art keywords
trifluoromethylphenothiazines
preparation
acid addition
addition salts
therapeutically active
Prior art date
Application number
NL227699A
Other languages
English (en)
Dutch (nl)
Other versions
NL105973C (nl
Original Assignee
Olin Mathieson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olin Mathieson filed Critical Olin Mathieson
Publication of NL227699A publication Critical patent/NL227699A/nl
Application granted granted Critical
Publication of NL105973C publication Critical patent/NL105973C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B7/00—Working up raw materials other than ores, e.g. scrap, to produce non-ferrous metals and compounds thereof; Methods of a general interest or applied to the winning of more than two metals
    • C22B7/006—Wet processes
    • C22B7/007—Wet processes by acid leaching
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P10/00—Technologies related to metal processing
    • Y02P10/20—Recycling

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental & Geological Engineering (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Metallurgy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NL227699A 1957-09-11 1958-05-12 Werkwijze ter bereiding van trifluormethylfenothiazinen met therapeutische werking en zuuradditiezouten daarvan NL105973C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68321957 US3227708A (en) 1957-09-11 1957-09-11 Trifluoromethyl phenothiazines

Publications (2)

Publication Number Publication Date
NL227699A true NL227699A (nl) 1963-04-16
NL105973C NL105973C (nl) 1963-09-16

Family

ID=24743059

Family Applications (1)

Application Number Title Priority Date Filing Date
NL227699A NL105973C (nl) 1957-09-11 1958-05-12 Werkwijze ter bereiding van trifluormethylfenothiazinen met therapeutische werking en zuuradditiezouten daarvan

Country Status (9)

Country Link
US (1) US3227708A (enExample)
BE (1) BE568837A (enExample)
CH (1) CH387044A (enExample)
DE (1) DE1212090B (enExample)
DK (1) DK118404B (enExample)
FR (1) FR1274378A (enExample)
GB (1) GB884760A (enExample)
NL (1) NL105973C (enExample)
SE (1) SE220505C1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3194733A (en) * 1961-04-26 1965-07-13 Olin Mathicson Chemical Corp Phenothiazine compositions and method of treating mental disorders
US3968118A (en) * 1968-08-31 1976-07-06 Hoechst Aktiengesellschaft Process for the manufacture of 1-hydroxy-2-pyridones
GB1460713A (en) * 1973-06-08 1977-01-06 Kefalas As 7-fluoro substituted phenothiazines method for preparation thereof and compositions bladed rotor for a gas turbine engine
ES2399977T3 (es) 2001-09-27 2013-04-04 Ramot At Tel Aviv University Ltd. Conjugado de perfenazina o flufenazina con ácidos carboxílicos
US7544681B2 (en) * 2001-09-27 2009-06-09 Ramot At Tel Aviv University Ltd. Conjugated psychotropic drugs and uses thereof
JP5284779B2 (ja) * 2005-06-07 2013-09-11 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド コンジュゲート化された向精神薬の新規な塩およびその調製方法
WO2008010223A2 (en) * 2006-07-17 2008-01-24 Ramot At Tel Aviv University Ltd. Conjugates comprising a psychotropic drug or a gaba agonist and an organic acid and their use in treating pain and other cns disorders
US8207369B2 (en) * 2008-02-11 2012-06-26 Ramot At Tel-Aviv University Ltd. Conjugates for treating neurodegenerative diseases and disorders
AU2010329440A1 (en) * 2009-12-09 2012-08-09 Bar-Ilan University Methods of improving cognitive functions
US8916610B2 (en) 2010-09-22 2014-12-23 Ramot At Tel-Aviv University Ltd. Acid addition salt of a nortriptyline-GABA conjugate and a process of preparing same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587660A (en) * 1952-03-04 Trifluoromethyl phenothiazine
US2838507A (en) * 1958-06-10 Chr-chi
US2678926A (en) * 1954-05-18 Dialkyl phsnoihiazins stulfoniss
US2645640A (en) * 1953-07-14 Phenthiazine derivatives
DE910301C (de) * 1950-12-21 1954-04-29 Rhone Poulenc Sa Verfahren zur Herstellung von neuen Phenthiazinderivaten
US2902484A (en) * 1954-04-27 1959-09-01 Rhone Poulenc Sa Phenthiazine derivatives and processes for their preparation
FR1171918A (fr) * 1954-10-18 1959-02-03 Rhone Poulenc Sa Nouveaux dérivés de la pipérazine et leurs procédés de préparation
BE553467A (enExample) * 1955-03-19
US2787617A (en) * 1955-09-20 1957-04-02 Searle & Co Derivatives of oxopiperazinoalkylhalophenothiazines
FR1186155A (fr) * 1956-04-07 1959-08-17 Rhone Poulenc Sa Nouveaux dérivés de la méthanesulfonyl-3 phénothiazine et leur procédé de préparation
NL108827C (enExample) * 1956-04-09
BE558008A (enExample) * 1956-06-21
BE569430A (enExample) * 1957-07-17

Also Published As

Publication number Publication date
CH387044A (fr) 1965-01-31
US3227708A (en) 1966-01-04
SE220505C1 (sv) 1968-05-14
FR1274378A (fr) 1961-10-27
BE568837A (fr) 1958-12-23
GB884760A (en) 1961-12-13
NL105973C (nl) 1963-09-16
DE1212090B (de) 1966-03-10
DK118404B (da) 1970-08-17

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