MY150793A - A microfluidic channel and methods of removing bubbles from fluid in the microfluidic channel - Google Patents

A microfluidic channel and methods of removing bubbles from fluid in the microfluidic channel

Info

Publication number
MY150793A
MY150793A MYPI2010005233A MY150793A MY 150793 A MY150793 A MY 150793A MY PI2010005233 A MYPI2010005233 A MY PI2010005233A MY 150793 A MY150793 A MY 150793A
Authority
MY
Malaysia
Prior art keywords
microfluidic channel
bubbles
fluid
methods
removing bubbles
Prior art date
Application number
Inventor
Lee Hing Wah
Daniel Bien Chia Dr Sheng
Original Assignee
Mimos Berhad
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mimos Berhad filed Critical Mimos Berhad
Priority to MYPI2010005233 priority Critical patent/MY150793A/en
Priority to PCT/MY2011/000083 priority patent/WO2012064172A1/en
Publication of MY150793A publication Critical patent/MY150793A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0851—Bottom walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G01N2035/1018—Detecting inhomogeneities, e.g. foam, bubbles, clots

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Micromachines (AREA)

Abstract

THE INVENTION DISCLOSES AN APPARATUS AND METHODS OF PUNCTURING BUBBLES FROM FLUID IN A MICROFLUIDIC CHANNEL (104). THE PRIMARY SHARP PROTUBERANCE (103) PUNCTURES THE LARGER BUBBLES. THE AIR VENT (102) TRAPS AND REMOVES THE BUBBLES CREATED AFTER THE LARGER BUBBLES HAVE BEEN BROKEN BY PRIMARY SHARP PROTUBERANCE (103). THE SECONDARY SHARP PROTUBERANCE (106) PUNCTURES THE ESCAPED BUBBLES WHICH WERE NOT BROKEN BY THE PRIMARY SHARP PROTUBERANCE (103) OR NOT REMOVED BY AIR VENT (102). VARIOUS SHARP PROTUBERANCES ARRAY CAN BE INTEGRATED INSIDE THE MICROFLUIDIC CHANNEL (104) TO PUNCTURE THE BUBBLES IN THE FLUID FLOW PATH. THE MOST ILLUSTRATIVE DRAWING: FIG 1
MYPI2010005233 2010-11-08 2010-11-08 A microfluidic channel and methods of removing bubbles from fluid in the microfluidic channel MY150793A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
MYPI2010005233 MY150793A (en) 2010-11-08 2010-11-08 A microfluidic channel and methods of removing bubbles from fluid in the microfluidic channel
PCT/MY2011/000083 WO2012064172A1 (en) 2010-11-08 2011-06-07 A microfluidic channel and methods of removing bubbles from fluid in the microfluidic channel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI2010005233 MY150793A (en) 2010-11-08 2010-11-08 A microfluidic channel and methods of removing bubbles from fluid in the microfluidic channel

Publications (1)

Publication Number Publication Date
MY150793A true MY150793A (en) 2014-02-28

Family

ID=46051148

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2010005233 MY150793A (en) 2010-11-08 2010-11-08 A microfluidic channel and methods of removing bubbles from fluid in the microfluidic channel

Country Status (2)

Country Link
MY (1) MY150793A (en)
WO (1) WO2012064172A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9962698B2 (en) 2012-09-05 2018-05-08 President And Fellows Of Harvard College Removing bubbles in microfluidic systems
CA3030421C (en) 2016-07-12 2021-11-09 EMULATE, Inc. Removing bubbles in a microfluidic device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050247198A1 (en) * 2004-05-07 2005-11-10 Kent Fraser C Method and apparatus for removing gas bubbles from a liquid
FI20085299A0 (en) * 2008-04-10 2008-04-10 Valtion Teknillinen Microfluidic chip devices and their use
EP2285576B1 (en) * 2008-06-05 2019-05-22 Hewlett-Packard Development Company, L.P. Reducing ink droplets generated by bursting bubbles in an ink developer

Also Published As

Publication number Publication date
WO2012064172A1 (en) 2012-05-18

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