MY103595A - (arylsulphonyl) nitromethanes, process for their preparation and use in pharmaceutical compositions - Google Patents

(arylsulphonyl) nitromethanes, process for their preparation and use in pharmaceutical compositions

Info

Publication number
MY103595A
MY103595A MYPI88000823A MYPI19880823A MY103595A MY 103595 A MY103595 A MY 103595A MY PI88000823 A MYPI88000823 A MY PI88000823A MY PI19880823 A MYPI19880823 A MY PI19880823A MY 103595 A MY103595 A MY 103595A
Authority
MY
Malaysia
Prior art keywords
pharmaceutical compositions
nitromethanes
arylsulphonyl
preparation
inhibitors
Prior art date
Application number
MYPI88000823A
Inventor
Preston John
Lawrence Longridge Jethro
James Morries Jeffrey
Loren Cooper Anthony
Paul Brown Steven
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888808117A external-priority patent/GB8808117D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of MY103595A publication Critical patent/MY103595A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

THE INVENTION CONCERNS NOVEL PHARMACEUTICAL COMPOSITIONS FOR USE IN THE TREATMENT OF CERTAIN COMPLICATIONS OF DIABETES AND GALACTOSEMIA AND WHICH CONTAIN A NITROMETHANE DERIVATIVE (OR ITS NON-TOXIC SALTS) AS ACTIVE INGREDIENT. THE NITROMETHANE DERIVATIVES ARE INHIBITORS OF THE ENZYME ALDOSE REDUCTASE. MANY OF THE INHIBITORS ARE NOVEL AND ARE PROVIDED, TOGETHER WITH PROCESSES FOR THEIR MANUFACTURE AND USE, AS FURTHER FEATURES OF THE INVENTION.
MYPI88000823A 1987-08-06 1988-07-21 (arylsulphonyl) nitromethanes, process for their preparation and use in pharmaceutical compositions MY103595A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878718619A GB8718619D0 (en) 1987-08-06 1987-08-06 Pharmaceutical compositions
GB888808117A GB8808117D0 (en) 1988-04-07 1988-04-07 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
MY103595A true MY103595A (en) 1993-08-28

Family

ID=26292578

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI88000823A MY103595A (en) 1987-08-06 1988-07-21 (arylsulphonyl) nitromethanes, process for their preparation and use in pharmaceutical compositions

Country Status (24)

Country Link
US (1) US5153227A (en)
EP (1) EP0304190B1 (en)
JP (1) JP2695852B2 (en)
KR (1) KR970008155B1 (en)
AU (1) AU620550B2 (en)
CA (1) CA1338646C (en)
DE (1) DE3872620T2 (en)
DK (1) DK435688A (en)
EG (1) EG18652A (en)
ES (1) ES2042753T3 (en)
FI (1) FI88713C (en)
GB (2) GB8718619D0 (en)
GR (1) GR3005126T3 (en)
HU (1) HU201004B (en)
IE (1) IE60913B1 (en)
IL (1) IL87201A (en)
MY (1) MY103595A (en)
NO (1) NO167797C (en)
NZ (1) NZ225488A (en)
PH (1) PH27185A (en)
PL (2) PL158324B1 (en)
PT (1) PT88201B (en)
YU (2) YU152288A (en)
ZW (1) ZW9988A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8810203D0 (en) * 1988-04-29 1988-06-02 Ici Plc Heterocyclic compounds
DE3823318A1 (en) * 1988-07-09 1990-02-22 Bayer Ag (HETERO) ARYLOXYNAPHTHALINE WITH SUBSTITUTES TIED ABOVE SULFUR
GB8902405D0 (en) * 1989-02-03 1989-03-22 Ici Plc Heterocyclic compounds
GB8902406D0 (en) * 1989-02-03 1989-03-22 Ici Plc Process
GB8902409D0 (en) * 1989-02-03 1989-03-22 Ici Plc Aliphatic compounds
IL93178A0 (en) * 1989-02-03 1990-11-05 Ici Plc Benzheterocyclyl sulphones
GB8902408D0 (en) * 1989-02-03 1989-03-22 Ici Plc Process
GB8902573D0 (en) * 1989-02-06 1989-03-22 Ici Plc Heterocyclic derivatives
IE63463B1 (en) * 1989-02-06 1995-04-19 Zeneca Ltd Phenylsulphone derivatives
US5250570A (en) * 1990-08-02 1993-10-05 Imperial Chemical Industries Plc Amidobenzene derivatives, compositions and use
GB9016980D0 (en) * 1990-08-02 1990-09-19 Ici Plc Amidobenzenes
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives
GB9016984D0 (en) * 1990-08-02 1990-09-19 Ici Plc Aniline derivatives
FR2757509B1 (en) * 1996-12-23 1999-03-26 Lipha NOVEL SULFONAMIDE AND SULFONYLUREA DERIVATIVES, THEIR PREPARATIONS AND MEDICAMENTS CONTAINING THEM
US5932765A (en) * 1997-05-23 1999-08-03 Merck Patent Gesellschaft Mit Nitromethyl ketones, process for preparing them and compositions containing them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3882247A (en) * 1972-04-21 1975-05-06 Du Pont Fungicidal nitro organic sulfur compounds
SU479761A1 (en) * 1973-07-18 1975-08-05 Институт Органической Химии Им. Н.Д.Зелинского Ан Ссср The method of obtaining-dinitroalkylsulfonov
US4053633A (en) * 1976-06-24 1977-10-11 The Dow Chemical Company Aryl dibromonitromethyl sulfones
FR2432316A1 (en) * 1978-08-02 1980-02-29 Choay Sa NOVEL MEDICINAL PRODUCTS CONTAINING, AS ACTIVE SUBSTANCE, BENZENESULFONE-LIKE COMPOUNDS, NOVEL SUCH COMPOUNDS AND PROCESS FOR THEIR PREPARATION
DE3326635A1 (en) * 1983-07-23 1985-01-31 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING MONOMETHYL-SUBSTITUTED METHYLENE COMPOUNDS

Also Published As

Publication number Publication date
US5153227A (en) 1992-10-06
AU1925488A (en) 1989-02-09
GB8718619D0 (en) 1987-09-09
HUT47243A (en) 1989-02-28
PL158324B1 (en) 1992-08-31
HU201004B (en) 1990-09-28
DE3872620D1 (en) 1992-08-13
PL274093A1 (en) 1990-02-19
DE3872620T2 (en) 1992-12-03
DK435688D0 (en) 1988-08-04
DK435688A (en) 1989-02-07
GB8816671D0 (en) 1988-08-17
IL87201A (en) 1995-08-31
YU152288A (en) 1990-06-30
NO167797C (en) 1991-12-11
EP0304190B1 (en) 1992-07-08
JP2695852B2 (en) 1998-01-14
AU620550B2 (en) 1992-02-20
JPS6479146A (en) 1989-03-24
KR890003365A (en) 1989-04-14
NO883500L (en) 1989-02-07
ZW9988A1 (en) 1990-03-14
CA1338646C (en) 1996-10-15
EG18652A (en) 1993-10-30
NZ225488A (en) 1990-12-21
NO883500D0 (en) 1988-08-05
FI883673A7 (en) 1989-02-07
EP0304190A1 (en) 1989-02-22
PT88201B (en) 1995-03-31
IE882195L (en) 1989-02-06
YU45090A (en) 1992-05-28
FI883673A0 (en) 1988-08-05
KR970008155B1 (en) 1997-05-21
PT88201A (en) 1989-06-30
FI88713B (en) 1993-03-15
PL157940B1 (en) 1992-07-31
PL281865A1 (en) 1990-07-09
FI88713C (en) 1993-06-28
ES2042753T3 (en) 1993-12-16
PH27185A (en) 1993-04-16
GB2207916A (en) 1989-02-15
IE60913B1 (en) 1994-08-24
GR3005126T3 (en) 1993-05-24
NO167797B (en) 1991-09-02
GB2207916B (en) 1992-03-25

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