MXPA05008523A - An expression cassette and vector for transient or stable expression of exogenous molecules. - Google Patents

An expression cassette and vector for transient or stable expression of exogenous molecules.

Info

Publication number
MXPA05008523A
MXPA05008523A MXPA05008523A MXPA05008523A MXPA05008523A MX PA05008523 A MXPA05008523 A MX PA05008523A MX PA05008523 A MXPA05008523 A MX PA05008523A MX PA05008523 A MXPA05008523 A MX PA05008523A MX PA05008523 A MXPA05008523 A MX PA05008523A
Authority
MX
Mexico
Prior art keywords
expression
vector
transient
expression cassette
cassette
Prior art date
Application number
MXPA05008523A
Other languages
Spanish (es)
Inventor
P Sisk William
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of MXPA05008523A publication Critical patent/MXPA05008523A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA

Abstract

The disclosure provides an expression cassette and a vector comprising the cassette for expression of a polynucleotide. The expression cassette includes a promoter/enhancer, an intervening region, and a polyadenylation signal domain. Expression systems and methods of using the expression cassette and vector are also provided.
MXPA05008523A 2003-02-14 2004-02-13 An expression cassette and vector for transient or stable expression of exogenous molecules. MXPA05008523A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44817903P 2003-02-14 2003-02-14
PCT/US2004/004407 WO2004074439A2 (en) 2003-02-14 2004-02-13 An expression cassette and vector for transient or stable expression of exogenous molecules

Publications (1)

Publication Number Publication Date
MXPA05008523A true MXPA05008523A (en) 2005-10-20

Family

ID=32908549

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05008523A MXPA05008523A (en) 2003-02-14 2004-02-13 An expression cassette and vector for transient or stable expression of exogenous molecules.

Country Status (22)

Country Link
US (2) US7494805B2 (en)
EP (1) EP1594955B1 (en)
JP (2) JP2006517802A (en)
KR (1) KR20050101554A (en)
CN (1) CN1774500B (en)
AT (1) ATE553185T1 (en)
AU (1) AU2004213797B2 (en)
BR (1) BRPI0407487A (en)
CA (1) CA2515481A1 (en)
DK (1) DK1594955T3 (en)
EA (2) EA008439B1 (en)
ES (1) ES2384973T3 (en)
HK (1) HK1084690A1 (en)
IL (1) IL170178A (en)
IS (1) IS7974A (en)
MX (1) MXPA05008523A (en)
NO (1) NO20054202L (en)
NZ (1) NZ542316A (en)
PL (1) PL378110A1 (en)
RS (1) RS20050614A (en)
WO (1) WO2004074439A2 (en)
ZA (1) ZA200506413B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1594955T3 (en) * 2003-02-14 2012-06-25 Biogen Idec Inc Expression cassette and vector for transient or stable expression of exogenous molecules
EA012241B1 (en) 2003-09-19 2009-08-28 Янссен Фармацевтика, Н.В. 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs thereof
MXPA06004121A (en) * 2003-10-14 2006-07-05 Biogen Idec Inc Flp-mediated recombination.
US7569362B2 (en) * 2004-03-15 2009-08-04 Biogen Idec Ma Inc. Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing
MY147518A (en) 2004-09-15 2012-12-31 Janssen Pharmaceutica Nv 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
JO3006B1 (en) 2005-09-14 2016-09-05 Janssen Pharmaceutica Nv Novel Lysine Salts of 4-((Phenoxy Alkyl)Thio)-Phenoxy Acetic Acid Derivatives
GB0606190D0 (en) 2006-03-28 2006-05-10 Isis Innovation Construct
PE20080188A1 (en) 2006-04-18 2008-03-10 Janssen Pharmaceutica Nv DERIVATIVES OF BENZOAZEPINE-OXY-ACETIC ACID AS PPAR-DELTA AGONISTS USED TO INCREASE HDL-C, REDUCE LDL-C AND REDUCE CHOLESTEROL
US20080166766A1 (en) * 2006-10-18 2008-07-10 The Scripps Research Institute Genetic incorporation of unnatural amino acids into proteins in mammalian cells
WO2011017319A1 (en) 2009-08-03 2011-02-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods of treating disorders associated with protein polymerization
US9072772B2 (en) 2009-11-05 2015-07-07 University of Pittsburgh—of the Commonwealth System of Higher Education Methods of treating disorders associated with protein aggregation
US8809617B2 (en) * 2009-11-05 2014-08-19 The University of Pittsburgh—Of the Commonwealth System of Higher Education Automated high-content live animal drug screening using C. elegans
NZ600711A (en) * 2009-12-21 2014-06-27 Sanofi Sa Transgenic non-human animal and uses thereof
UY33126A (en) * 2009-12-21 2011-07-29 Sanofi Sa NON-HUMAN TRANSGENIC ANIMAL AND ITS USES
US8993316B2 (en) 2011-11-16 2015-03-31 Brian P. Hanley Methods and compositions for gene therapy and GHRH therapy
WO2013158664A2 (en) 2012-04-17 2013-10-24 Kythera Biopharmaceuticals, Inc. Use of engineered viruses to specifically kill senescent cells
WO2014042923A1 (en) 2012-09-13 2014-03-20 Indiana University Research & Technology Corporation Compositions and systems for conferring disease resistance in plants and methods of use thereof
LT2928923T (en) 2012-12-10 2020-02-25 Biogen Ma Inc. Anti-blood dendritic cell antigen 2 antibodies and uses thereof
AU2014246731A1 (en) * 2013-03-30 2015-11-19 Usha Biotech Limited Methods and constructs for expressing biologically active proteins in mammalian cells
US20170183389A1 (en) * 2014-04-24 2017-06-29 Accurna, Inc. Method for improving protein expression, and composition for protein expression
TWI747098B (en) 2018-12-21 2021-11-21 美商美國禮來大藥廠 Anti-angptl3/8 complex antibodies and methods of using the same
US11415263B2 (en) * 2020-03-20 2022-08-16 Edwards Vacuum Llc Conversion kit for a support frame, a support frame and an integrated vacuum system mounted in a support frame

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
ATE274055T1 (en) 1991-10-25 2004-09-15 Immunex Corp NEW CYTOKINE
ATE229076T1 (en) 1992-04-02 2002-12-15 Sembiosys Genetics Inc CIS ELEMENTS OF OIL BODY PROTEIN AS REGULATIONAL SIGNALS
JPH10510433A (en) 1995-06-06 1998-10-13 アイシス・ファーマシューティカルス・インコーポレーテッド Oligonucleotides with high chiral purity phosphorothioate linkages
EP0832229B1 (en) 1995-06-07 2004-01-14 Immunex Corporation Cd40l mutein
US5985662A (en) 1995-07-13 1999-11-16 Isis Pharmaceuticals Inc. Antisense inhibition of hepatitis B virus replication
US6087129A (en) 1996-01-19 2000-07-11 Betagene, Inc. Recombinant expression of proteins from secretory cell lines
AU2809897A (en) * 1996-04-23 1997-11-12 Wistar Institute Of Anatomy And Biology, The Novel human cytomegalovirus dna constructs and uses therefor
US6423693B1 (en) * 1997-07-24 2002-07-23 Baylor College Of Medicine Growth hormone releasing hormone expression system and methods of use, including use in animals
JP2002508956A (en) 1998-01-16 2002-03-26 カリフォルニア パシフィック メディカル センター リサーチ インスティテュート Methods and compositions for gene delivery
EP0953639A1 (en) * 1998-04-30 1999-11-03 Boehringer Ingelheim International GmbH FAPalpha-specific antibody with improved producibility
US6455677B1 (en) * 1998-04-30 2002-09-24 Boehringer Ingelheim International Gmbh FAPα-specific antibody with improved producibility
JP2002516295A (en) * 1998-05-27 2002-06-04 アビジェン， インコーポレイテッド Convective increased delivery of AAV vectors
EP1092768A1 (en) * 1999-10-16 2001-04-18 ARTEMIS Pharmaceuticals GmbH Conditional gene trapping construct for the disruption of genes
AU2001264488A1 (en) 2000-06-07 2001-12-17 Smittskyddsinstitutet Gene expression cassette and its use
AU7061401A (en) 2000-07-05 2002-01-14 Transgene Sa Chimeric promoters for controlling expression in smooth muscle cells
JP2002233374A (en) * 2001-02-06 2002-08-20 Japan Science & Technology Corp Vector for creating non-human animal in which gene is transduced and/or deleted
DE10133407A1 (en) 2001-07-13 2003-01-23 Basf Ag New expression cassette for transgene expression, useful particularly in selection of transformed plants, contain specific constitutive Arabidopsis promoters
US20030235823A1 (en) 2002-06-24 2003-12-25 The University Of Alabama Nucleotide sequences that code for torsin genes, torsin proteins, and methods of using the same to treat protein-aggregation
DK1594955T3 (en) 2003-02-14 2012-06-25 Biogen Idec Inc Expression cassette and vector for transient or stable expression of exogenous molecules

Also Published As

Publication number Publication date
KR20050101554A (en) 2005-10-24
EP1594955B1 (en) 2012-04-11
RS20050614A (en) 2007-12-31
JP2006517802A (en) 2006-08-03
PL378110A1 (en) 2006-03-06
ES2384973T3 (en) 2012-07-16
AU2004213797A1 (en) 2004-09-02
NZ542316A (en) 2006-04-28
EP1594955A4 (en) 2006-07-19
EA200700469A1 (en) 2008-10-30
CA2515481A1 (en) 2004-09-02
EA008439B1 (en) 2007-06-29
NO20054202D0 (en) 2005-09-09
BRPI0407487A (en) 2006-02-14
EA200501296A1 (en) 2006-04-28
WO2004074439A2 (en) 2004-09-02
CN1774500A (en) 2006-05-17
ATE553185T1 (en) 2012-04-15
US20100158879A1 (en) 2010-06-24
AU2004213797B2 (en) 2009-09-17
DK1594955T3 (en) 2012-06-25
US20060141625A1 (en) 2006-06-29
ZA200506413B (en) 2006-04-26
WO2004074439A3 (en) 2004-10-28
JP2010213718A (en) 2010-09-30
NO20054202L (en) 2005-11-11
EP1594955A2 (en) 2005-11-16
US7494805B2 (en) 2009-02-24
HK1084690A1 (en) 2006-08-04
IL170178A (en) 2011-12-29
CN1774500B (en) 2011-03-02
WO2004074439A9 (en) 2004-12-23
IS7974A (en) 2005-08-11

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