MX9605371A - Derivados de purin-6-ona y procedimiento para su produccion. - Google Patents

Derivados de purin-6-ona y procedimiento para su produccion.

Info

Publication number
MX9605371A
MX9605371A MX9605371A MX9605371A MX9605371A MX 9605371 A MX9605371 A MX 9605371A MX 9605371 A MX9605371 A MX 9605371A MX 9605371 A MX9605371 A MX 9605371A MX 9605371 A MX9605371 A MX 9605371A
Authority
MX
Mexico
Prior art keywords
purin
derivatives
production
diseases
acilating
Prior art date
Application number
MX9605371A
Other languages
English (en)
Inventor
Ulrich Niewolhner
Erwin Bischoff
Joachim Hutter
Elisabeth Perzborn
Helmut Schutz
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX9605371A publication Critical patent/MX9605371A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Los derivados de purin-6-ona se obtienen al acilar imidazol-carboxamidas sustituidas y ciclar a continuacion para obtener las purinas. Los derivados de purin-6-ona son adecuados como sustancia activa en medicamentos especialmente para el tratamiento de enfermedades cardiovasculares, enfermedades de los vasos sanguíneos periféricos así como del sistema urogenital.
MX9605371A 1995-11-06 1996-11-05 Derivados de purin-6-ona y procedimiento para su produccion. MX9605371A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19541264A DE19541264A1 (de) 1995-11-06 1995-11-06 Purin-6-on-derivate

Publications (1)

Publication Number Publication Date
MX9605371A true MX9605371A (es) 1997-05-31

Family

ID=7776713

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9605371A MX9605371A (es) 1995-11-06 1996-11-05 Derivados de purin-6-ona y procedimiento para su produccion.

Country Status (23)

Country Link
US (1) US5861396A (es)
EP (1) EP0771799A1 (es)
JP (1) JPH09124648A (es)
KR (1) KR970027082A (es)
AR (1) AR004545A1 (es)
AU (1) AU720305B2 (es)
BR (1) BR9605434A (es)
CA (1) CA2189401A1 (es)
CO (1) CO4770977A1 (es)
CZ (1) CZ325096A3 (es)
DE (1) DE19541264A1 (es)
EE (1) EE9600172A (es)
HU (1) HU217691B (es)
IL (1) IL119559A0 (es)
MX (1) MX9605371A (es)
NO (1) NO964667L (es)
NZ (1) NZ299683A (es)
PL (1) PL316816A1 (es)
SG (1) SG64953A1 (es)
SK (1) SK142596A3 (es)
TR (1) TR199600883A2 (es)
TW (1) TW360656B (es)
ZA (1) ZA969278B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6579868B1 (en) * 1998-01-05 2003-06-17 Eisai Co., Ltd. Purine derivatives and adenosine A2 receptor antagonists serving as preventives/remedies for diabetes
DE19838705A1 (de) * 1998-08-26 2000-03-02 Bayer Ag Neue Dihydro-(1,2,3)-triazolo-[4,5-d]pyrimidin-7-one
GB9828340D0 (en) * 1998-12-22 1999-02-17 Novartis Ag Organic compounds
IL139456A0 (en) * 1999-11-08 2001-11-25 Pfizer Compounds for the treatment of female sexual dysfunction
US20050020547A1 (en) * 1999-11-08 2005-01-27 Pfizer Inc. Compounds for the treatment of female sexual dysfunction
CA2417631A1 (en) 2000-08-01 2003-01-29 Bayer Aktiengesellschaft Selective pde 2 inhibitors, used as medicaments for improving cognition
US20020065286A1 (en) * 2000-08-21 2002-05-30 Davies Michael John Treatment of wounds
NZ524572A (en) * 2000-09-06 2004-08-27 Tanabe Seiyaku Co Oral compositions comprising phosphodiesterase inhibitors ( PDE inhibitor )and an acidic substance such as fumaric acid with improved drug efficacy due to decrease solubility in neutral and alkaline regions
DE10064105A1 (de) 2000-12-21 2002-06-27 Bayer Ag Neue Substituierte Imidazotriazinone
US7927623B2 (en) * 2001-02-15 2011-04-19 Mitsubishi Tanabe Pharma Corporation Tablets quickly disintegrated in oral cavity
ATE324371T1 (de) 2001-02-23 2006-05-15 Merck & Co Inc N-substituierte heterocyclische nichtaryl- nmda/nr2b-antagonisten
US6479493B1 (en) 2001-08-23 2002-11-12 Cell Pathways, Inc. Methods for treatment of type I diabetes
IL161155A0 (en) * 2001-11-02 2004-08-31 Pfizer Prod Inc Treatment of insulin resistance syndrome and type 2 diabetes with pde9 inhibitors
AU2004228360A1 (en) * 2003-03-04 2004-10-21 Altana Pharma Ag Purin-6-one-derivatives
US20040220186A1 (en) * 2003-04-30 2004-11-04 Pfizer Inc. PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease
GB0314054D0 (en) * 2003-06-17 2003-07-23 Pfizer Ltd Amide derivatives as selective serotonin re-uptake inhibitors
US20050054688A1 (en) * 2003-08-08 2005-03-10 Pfizer Inc Selective serotonin reuptake inhibitors in the treatment of disease
EP1660132A1 (en) * 2003-08-28 2006-05-31 ALTANA Pharma AG Composition comprising a pulmonary surfactant and a pde2 inhibitor
US7291640B2 (en) * 2003-09-22 2007-11-06 Pfizer Inc. Substituted triazole derivatives as oxytocin antagonists
GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds
CA2602198C (en) * 2005-03-21 2010-11-09 Pfizer Limited Substituted triazole derivatives as oxytocin antagonists
JP2008533193A (ja) * 2005-03-21 2008-08-21 ファイザー・リミテッド オキシトシン拮抗薬としての置換トリアゾール誘導体
EP1917257A1 (en) * 2005-08-10 2008-05-07 Pfizer Limited Substituted triazole derivatives as oxytocin antagonists
US9849132B2 (en) 2014-01-08 2017-12-26 Intra-Cellular Therapies, Inc. Products and pharmaceutical compositions
JP6608934B2 (ja) 2014-12-06 2019-11-20 イントラ−セルラー・セラピーズ・インコーポレイテッド 有機化合物
KR102562576B1 (ko) 2014-12-06 2023-08-01 인트라-셀룰라 써래피스, 인코퍼레이티드. 유기 화합물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451478A (en) * 1982-03-12 1984-05-29 Newport Pharmaceuticals International, Inc. Imidazole compounds
IL76546A (en) * 1984-10-12 1988-12-30 Warner Lambert Co 9-(heteroarylalkyl)-6-purine(thi)one derivatives,their preparation and pharmaceutical compositions containing them
US4916225A (en) * 1986-11-25 1990-04-10 Institut Organicheskogo Sinteza Akademii Nauk Latviiskoi Ssr 9-substituted guanines
IT1241452B (it) * 1990-06-28 1994-01-17 Sigma Tau Ind Farmaceuti Derivati oligopeptidici dell'ipoxantina dotati di attivita' immunomodulante e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
EE9600172A (et) 1997-06-16
HUP9603071A2 (en) 1997-05-28
SK142596A3 (en) 1997-05-07
US5861396A (en) 1999-01-19
TR199600883A2 (tr) 1997-05-21
KR970027082A (ko) 1997-06-24
AR004545A1 (es) 1998-12-16
IL119559A0 (en) 1997-02-18
BR9605434A (pt) 1998-08-04
PL316816A1 (en) 1997-05-12
CO4770977A1 (es) 1999-04-30
CA2189401A1 (en) 1997-05-07
SG64953A1 (en) 1999-05-25
HUP9603071A3 (en) 1998-04-28
CZ325096A3 (en) 1997-06-11
AU720305B2 (en) 2000-05-25
DE19541264A1 (de) 1997-05-07
EP0771799A1 (de) 1997-05-07
HU9603071D0 (en) 1996-12-30
NZ299683A (en) 1998-09-24
NO964667L (no) 1997-05-07
TW360656B (en) 1999-06-11
HU217691B (hu) 2000-03-28
NO964667D0 (no) 1996-11-05
AU7053296A (en) 1997-05-15
ZA969278B (en) 1997-06-02
JPH09124648A (ja) 1997-05-13

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