MX389712B - Formulacion inyectable de una lactona macrociclica y levamisol. - Google Patents

Formulacion inyectable de una lactona macrociclica y levamisol.

Info

Publication number
MX389712B
MX389712B MX2018007637A MX2018007637A MX389712B MX 389712 B MX389712 B MX 389712B MX 2018007637 A MX2018007637 A MX 2018007637A MX 2018007637 A MX2018007637 A MX 2018007637A MX 389712 B MX389712 B MX 389712B
Authority
MX
Mexico
Prior art keywords
macrocyclic lactone
levamisol
injectable formulation
levamisole
sub
Prior art date
Application number
MX2018007637A
Other languages
English (en)
Other versions
MX2018007637A (es
Inventor
Luis Fernando Vettorato
Luiz Daniel Cortez
Ulisses Rafael Santos Assis
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of MX2018007637A publication Critical patent/MX2018007637A/es
Publication of MX389712B publication Critical patent/MX389712B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a formulaciones para controlar parásitos, que comprende una combinación de un compuesto de lactona macrocíclica y levamisol, en donde el levamisol está en forma particulada suspendida en triacetina y tiene un tamaño de partícula efectivo promedio (D50) de = 250 µm.
MX2018007637A 2015-12-22 2016-12-21 Formulacion inyectable de una lactona macrociclica y levamisol. MX389712B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562270721P 2015-12-22 2015-12-22
PCT/EP2016/082188 WO2017108954A1 (en) 2015-12-22 2016-12-21 Injectable formulation of a macrocyclic lactone and levamisole

Publications (2)

Publication Number Publication Date
MX2018007637A MX2018007637A (es) 2018-09-21
MX389712B true MX389712B (es) 2025-03-20

Family

ID=57629585

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018007637A MX389712B (es) 2015-12-22 2016-12-21 Formulacion inyectable de una lactona macrociclica y levamisol.

Country Status (6)

Country Link
EP (1) EP3393455B1 (es)
AR (1) AR107108A1 (es)
AU (2) AU2016377165B2 (es)
BR (1) BR112018012886B1 (es)
MX (1) MX389712B (es)
WO (1) WO2017108954A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2970570T3 (es) * 2017-11-07 2024-05-29 Intervet Int Bv Composiciones farmacéuticas inyectables de isoxazolina y su uso contra una infestación por parásitos
EP4208157A1 (en) 2020-09-04 2023-07-12 Elanco Us Inc. Palatable formulations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1375291A (zh) * 2001-03-16 2002-10-23 王玉万 一种含左旋咪唑或其盐类的兽用复方注射剂
NZ552040A (en) * 2006-12-13 2009-04-30 Bomac Research Ltd Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
NZ594610A (en) * 2011-08-16 2013-03-28 Virbac New Zealand Ltd Injectable Anthelmintic Formulations cotaining levamisole and one or more macrocyclic lactones for controlling internal parasites in ruminants
WO2013043064A1 (en) * 2011-09-23 2013-03-28 Alleva Animal Health Limited Veterinary anthelmintic delivery system
CN104983680A (zh) * 2015-06-25 2015-10-21 中国科学院东北地理与农业生态研究所 一种羊用复方驱虫药的稳定性纳米悬浮制剂及其制备方法

Also Published As

Publication number Publication date
AU2016377165B2 (en) 2022-08-11
WO2017108954A1 (en) 2017-06-29
AU2016377165A1 (en) 2018-06-14
AU2022268378A1 (en) 2022-12-15
AR107108A1 (es) 2018-03-21
BR112018012886A2 (pt) 2018-12-04
EP3393455B1 (en) 2021-07-21
BR112018012886B1 (pt) 2024-02-15
EP3393455A1 (en) 2018-10-31
MX2018007637A (es) 2018-09-21
NZ742888A (en) 2024-07-26

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