MX363228B - Proceso para preparar clorhidrato de oxicodona teniendo menos de 25 ppm 14-hidroxicodeinona. - Google Patents

Proceso para preparar clorhidrato de oxicodona teniendo menos de 25 ppm 14-hidroxicodeinona.

Info

Publication number
MX363228B
MX363228B MX2013004023A MX2013004023A MX363228B MX 363228 B MX363228 B MX 363228B MX 2013004023 A MX2013004023 A MX 2013004023A MX 2013004023 A MX2013004023 A MX 2013004023A MX 363228 B MX363228 B MX 363228B
Authority
MX
Mexico
Prior art keywords
hydroxycodeinone
ppm
less
oxycodone hydrochloride
preparing oxycodone
Prior art date
Application number
MX2013004023A
Other languages
English (en)
Inventor
Kyle Donald
Chapman Robert
S Rider Lonn
Hong Qi
Kupper Robert
Original Assignee
Euro Celtique S A Star
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35124996&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX363228(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Euro Celtique S A Star filed Critical Euro Celtique S A Star
Publication of MX363228B publication Critical patent/MX363228B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C07D489/04—Salts; Organic complexes

Abstract

En ciertas modalidades, la invención está dirigida hacia un proceso para preparar una composición de clorhidrato de oxicodona teniendo menos de 25 ppm de 14-hidroxicodeinona.
MX2013004023A 2004-03-30 2005-03-30 Proceso para preparar clorhidrato de oxicodona teniendo menos de 25 ppm 14-hidroxicodeinona. MX363228B (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US55749204P 2004-03-30 2004-03-30
US60153404P 2004-08-13 2004-08-13
US62007204P 2004-10-18 2004-10-18
US64862505P 2005-01-31 2005-01-31
US65177805P 2005-02-10 2005-02-10
PCT/US2005/010666 WO2005097801A1 (en) 2004-03-30 2005-03-30 Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone

Publications (1)

Publication Number Publication Date
MX363228B true MX363228B (es) 2019-03-15

Family

ID=35124996

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013004023A MX363228B (es) 2004-03-30 2005-03-30 Proceso para preparar clorhidrato de oxicodona teniendo menos de 25 ppm 14-hidroxicodeinona.
MX2020008878A MX2020008878A (es) 2004-03-30 2006-09-08 Proceso para preparar clorhidrato de oxicodona teniendo menos de 25 ppm 14-hidroxicodeinona.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2020008878A MX2020008878A (es) 2004-03-30 2006-09-08 Proceso para preparar clorhidrato de oxicodona teniendo menos de 25 ppm 14-hidroxicodeinona.

Country Status (39)

Country Link
US (35) US7129248B2 (es)
EP (7) EP1730151B2 (es)
JP (8) JP4912294B2 (es)
KR (12) KR20180088505A (es)
CN (5) CN1960994B (es)
AP (1) AP2232A (es)
AR (1) AR049012A1 (es)
AT (2) ATE501150T1 (es)
AU (2) AU2005230826C1 (es)
BR (1) BRPI0508758B8 (es)
CA (3) CA2557845C (es)
CR (2) CR8593A (es)
CY (5) CY1111487T1 (es)
DE (2) DE202005021371U1 (es)
DK (6) DK1730151T4 (es)
EA (1) EA013208B1 (es)
EC (1) ECSP066953A (es)
ES (6) ES2938727T3 (es)
FI (1) FI7843U1 (es)
HK (3) HK1098745A1 (es)
HR (5) HRP20110425T4 (es)
HU (3) HUE029913T2 (es)
IL (8) IL178038A (es)
LT (2) LT2314589T (es)
MA (1) MA28492B1 (es)
ME (4) ME02411B (es)
MX (2) MX363228B (es)
MY (3) MY154985A (es)
NO (1) NO337669B1 (es)
NZ (3) NZ602862A (es)
PE (1) PE20050880A1 (es)
PL (5) PL2305683T3 (es)
PT (5) PT1730151E (es)
RS (5) RS51693B2 (es)
SG (3) SG170736A1 (es)
SI (5) SI2316837T1 (es)
TW (3) TW201509943A (es)
WO (1) WO2005097801A1 (es)
ZA (1) ZA200607181B (es)

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