MX2022006103A - Procesos para la preparación de alfa-hidroxiésteres mediante reacciones de acoplamiento de grignard y tiolación. - Google Patents

Procesos para la preparación de alfa-hidroxiésteres mediante reacciones de acoplamiento de grignard y tiolación.

Info

Publication number
MX2022006103A
MX2022006103A MX2022006103A MX2022006103A MX2022006103A MX 2022006103 A MX2022006103 A MX 2022006103A MX 2022006103 A MX2022006103 A MX 2022006103A MX 2022006103 A MX2022006103 A MX 2022006103A MX 2022006103 A MX2022006103 A MX 2022006103A
Authority
MX
Mexico
Prior art keywords
alpha
processes
hydroxy esters
preparation
esters via
Prior art date
Application number
MX2022006103A
Other languages
English (en)
Inventor
Li Xu
Ye Lao
Shengshu Huang
Fangyi Li
Filip Nuyens
Jatuporn Salaklang
Original Assignee
Kemin Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kemin Ind Inc filed Critical Kemin Ind Inc
Publication of MX2022006103A publication Critical patent/MX2022006103A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/18—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by addition of thiols to unsaturated compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente divulgación proporciona procesos para preparar un alfa-hidroxiéster mediante la adición de un reactivo vinílico de Grignard a un éster de oxalato y la tiolación del doble enlace resultante. También se proporcionan alfa-hidroxiésteres e intermedios sintéticos preparados de acuerdo con los procesos divulgados en el presente documento y composiciones que comprenden los alfa-hidroxiésteres.
MX2022006103A 2019-11-22 2020-11-19 Procesos para la preparación de alfa-hidroxiésteres mediante reacciones de acoplamiento de grignard y tiolación. MX2022006103A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2019120393 2019-11-22
PCT/US2020/061242 WO2021102115A1 (en) 2019-11-22 2020-11-19 Processes for the preparation of alpha-hydroxy esters via grignard coupling and thiolation reactions

Publications (1)

Publication Number Publication Date
MX2022006103A true MX2022006103A (es) 2022-07-19

Family

ID=75981073

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022006103A MX2022006103A (es) 2019-11-22 2020-11-19 Procesos para la preparación de alfa-hidroxiésteres mediante reacciones de acoplamiento de grignard y tiolación.

Country Status (11)

Country Link
US (1) US20230002315A1 (es)
EP (1) EP4061362A4 (es)
JP (1) JP2023502569A (es)
KR (1) KR20220103930A (es)
CN (1) CN114727988A (es)
AU (1) AU2020386535A1 (es)
BR (1) BR112022008119A2 (es)
CA (1) CA3161569A1 (es)
CO (1) CO2022008527A2 (es)
MX (1) MX2022006103A (es)
WO (1) WO2021102115A1 (es)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY109603A (en) * 1992-05-21 1997-03-31 Daicel Chem Process for producing 2-hydroxy-4-methylthiobutanoic acid
WO2001058864A1 (en) * 2000-02-07 2001-08-16 Rhone-Poulenc Animal Nutrition Process for the preparation of 2-hydroxy-4-methylthio butyric acid esters
WO2008010609A1 (en) * 2006-07-21 2008-01-24 Sumitomo Chemical Company, Limited Process for producing 2-hydroxy-4-(methylthio)butyrate compounds and intermediates thereof
DE102007031917A1 (de) * 2007-07-09 2009-01-15 Evonik Degussa Gmbh Verfahren zur Herstellung von Ketosäuren und deren Derivaten
JP2012126651A (ja) * 2010-12-13 2012-07-05 Sumitomo Chemical Co Ltd ヒドロキシカルボン酸化合物またはその塩の製造方法
CN102093271A (zh) * 2011-01-25 2011-06-15 张维军 2-羟基-4-甲硫基丁酸烷基酯的制备方法
CN105175443B (zh) * 2015-08-17 2017-04-19 湖南海利化工股份有限公司 一种含磷α酮酸酯的制备方法
CA3150773A1 (en) * 2019-09-06 2021-03-11 Kemin Industries, Inc. Processes for the preparation of alpha-hydroxy esters by esterification of alpha-hydroxy acids

Also Published As

Publication number Publication date
CO2022008527A2 (es) 2022-06-30
BR112022008119A2 (pt) 2022-09-27
CA3161569A1 (en) 2021-05-27
EP4061362A4 (en) 2024-01-03
KR20220103930A (ko) 2022-07-25
AU2020386535A1 (en) 2022-05-26
WO2021102115A1 (en) 2021-05-27
EP4061362A1 (en) 2022-09-28
CN114727988A (zh) 2022-07-08
JP2023502569A (ja) 2023-01-25
US20230002315A1 (en) 2023-01-05

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