MX2021003797A - Terapias inmunoablativas. - Google Patents
Terapias inmunoablativas.Info
- Publication number
- MX2021003797A MX2021003797A MX2021003797A MX2021003797A MX2021003797A MX 2021003797 A MX2021003797 A MX 2021003797A MX 2021003797 A MX2021003797 A MX 2021003797A MX 2021003797 A MX2021003797 A MX 2021003797A MX 2021003797 A MX2021003797 A MX 2021003797A
- Authority
- MX
- Mexico
- Prior art keywords
- immunoablative
- therapies
- diseases
- treatment
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/547—Chelates, e.g. Gd-DOTA or Zinc-amino acid chelates; Chelate-forming compounds, e.g. DOTA or ethylenediamine being covalently linked or complexed to the pharmacologically- or therapeutically-active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
Abstract
Esta invención se relaciona con composiciones farmacéuticas que comprenden un glucocorticoide para utilizarse en el tratamiento de enfermedades mediante inmunoablación. Las composiciones de la invención se pueden utilizar en el tratamiento de enfermedades que son intervenidas por células inmunes tales como linfocitos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18198491.5A EP3488851A1 (en) | 2018-10-03 | 2018-10-03 | Immunoablative therapies |
PCT/US2019/054395 WO2020072713A1 (en) | 2018-10-03 | 2019-10-03 | Immunoablative therapies |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021003797A true MX2021003797A (es) | 2021-08-11 |
Family
ID=63762311
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021003797A MX2021003797A (es) | 2018-10-03 | 2019-10-03 | Terapias inmunoablativas. |
Country Status (14)
Country | Link |
---|---|
US (2) | US11446314B2 (es) |
EP (2) | EP3488851A1 (es) |
JP (1) | JP2020059703A (es) |
KR (1) | KR20210072039A (es) |
CN (1) | CN113164497A (es) |
AU (1) | AU2019355004A1 (es) |
BR (1) | BR112021006280A2 (es) |
CA (1) | CA3113969A1 (es) |
EA (1) | EA202190927A1 (es) |
ES (1) | ES2863369T3 (es) |
MX (1) | MX2021003797A (es) |
SG (1) | SG11202103031SA (es) |
WO (1) | WO2020072713A1 (es) |
ZA (1) | ZA202102727B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3488851A1 (en) | 2018-10-03 | 2019-05-29 | AVM Biotechnology, LLC | Immunoablative therapies |
KR20220130253A (ko) * | 2018-11-14 | 2022-09-26 | 에이브이엠 바이오테크놀로지, 엘엘씨 | 안정한 글루코코르티코이드 제제 |
US20230096897A1 (en) * | 2020-02-28 | 2023-03-30 | Avm Biotechnology, Llc | Lymphocyte Population and Methods for Producing Same |
KR20230015927A (ko) | 2020-04-29 | 2023-01-31 | 에이브이엠 바이오테크놀로지, 엘엘씨 | Sars-cov-2 바이러스 치료를 위한 글루코코르티코이드 수용체(gr) 조절제 |
WO2021247000A1 (en) * | 2020-06-01 | 2021-12-09 | Avm Biotechnology, Llc | Methods of treatment using icam-modulating agents |
KR20220163638A (ko) | 2021-06-03 | 2022-12-12 | 현대모비스 주식회사 | 차량용 제동장치 및 그 제어방법 |
EP4395784A1 (en) | 2021-09-01 | 2024-07-10 | AVM Biotechnology, LLC | Lymphocyte population and methods for producing same |
Family Cites Families (41)
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US3368937A (en) * | 1965-01-26 | 1968-02-13 | Merck & Co Inc | Injectable solid steroid-anesthetic |
US4554271A (en) * | 1984-02-24 | 1985-11-19 | The Upjohn Company | Use of high doses of derivatives of 6α-methylprednisolone for the acute treatment of stroke syndrome |
US5728388A (en) | 1989-10-03 | 1998-03-17 | Terman; David S. | Method of cancer treatment |
GB9323199D0 (en) | 1993-11-10 | 1994-01-05 | Falkenberg J H F | Leukaemia treatment |
JPH10507758A (ja) * | 1994-10-19 | 1998-07-28 | ジェネティック セラピー,インコーポレイテッド | アデノウイルスおよび免疫抑制剤同時反復投与を伴う遺伝子治療 |
EP0938896A1 (en) * | 1998-01-15 | 1999-09-01 | Novartis AG | Autoclavable pharmaceutical compositions containing a chelating agent |
US6406699B1 (en) | 1999-10-05 | 2002-06-18 | Gary W. Wood | Composition and method of cancer antigen immunotherapy |
IL146970A0 (en) | 2001-12-06 | 2002-08-14 | Yeda Res & Dev | Migration of haematopoietic stem cells and progenitor cells to the liver |
EP1499347A2 (en) | 2002-03-15 | 2005-01-26 | Department of Veterans Affairs, Rehabilitation R&D Service | Methods and compositions using cellular asialodeterminants and glycoconjugates for targeting cells to tissues and organs |
EP1539240A2 (en) * | 2002-05-02 | 2005-06-15 | The Washington University | Methods and compositions for treating t cell mediated inflammatory/autoimmune diseases and disorders in subjects having a glucocorticoid regulation deficiency |
EP1502012A4 (en) * | 2002-05-08 | 2009-07-01 | Btu Int | EXHAUST GAS TREATMENT OF A PLASMA ASSISTED ENGINE |
CN102429908A (zh) | 2002-05-17 | 2012-05-02 | 细胞基因公司 | 用于治疗和控制多发性骨髓瘤的方法及组合物 |
JP3968334B2 (ja) | 2002-09-11 | 2007-08-29 | 株式会社日立ハイテクノロジーズ | 荷電粒子線装置及び荷電粒子線照射方法 |
GB0310593D0 (en) | 2003-05-08 | 2003-06-11 | Leuven K U Res & Dev | Peptidic prodrugs |
US20040247574A1 (en) | 2003-05-27 | 2004-12-09 | Christopherson Kent W. | Methods for enhancing stem cell engraftment during transplantation |
EP1835924B1 (en) | 2004-12-23 | 2013-08-21 | Ethicon, Incorporated | Treatment of parkinson's disease and related disorders using postpartum derived cells |
SI1888033T1 (sl) * | 2005-06-09 | 2014-06-30 | Meda Ab | Postopek in sestavek za zdravljenje vnetnih motenj |
DE102005030733A1 (de) * | 2005-07-01 | 2007-01-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff |
BRPI0613770A2 (pt) | 2005-07-22 | 2009-05-19 | Y S Therapeutics Co Ltd | anticorpos anti-cd26 e métodos de uso destes |
US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
GB0700058D0 (en) | 2007-01-03 | 2007-02-07 | Scancell Aps | Anti-tumor vaccine based on normal cells |
WO2008094689A2 (en) | 2007-02-01 | 2008-08-07 | Nephrogen, Llc | Potentiation of stem cell homing and treatment of organ dysfunction or organ failure |
US20090299269A1 (en) | 2008-05-29 | 2009-12-03 | John Foley | Vascular stimulation to aid intravascular cell replacement therapy |
WO2009152186A1 (en) | 2008-06-09 | 2009-12-17 | American Stem Cell, Inc. | Methods for enhancing cell therapy efficacy including treatment with cd26 peptidase inhibitors |
ES2627043T3 (es) | 2008-06-09 | 2017-07-26 | Targazyme, Inc. | Aumento de la eficacia de la terapia celular incluyendo tratamiento con alfa 1-3 fucoslitransferasa |
JP5537104B2 (ja) * | 2009-09-16 | 2014-07-02 | テルモ株式会社 | 制吐剤 |
SG187840A1 (en) | 2010-08-18 | 2013-03-28 | Theresa Deisher | Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues |
US10426740B1 (en) | 2010-08-18 | 2019-10-01 | Avm Biotechnology, Llc | Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues |
LT3214091T (lt) | 2010-12-09 | 2018-12-10 | The Trustees Of The University Of Pennsylvania | Modifikuotų t ląstelių, turinčių chimerinį antigeno receptorių, panaudojimas vėžio gydymui |
KR20140004174A (ko) | 2011-01-18 | 2014-01-10 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 암 치료를 위한 조성물 및 방법 |
EP2532740A1 (en) | 2011-06-11 | 2012-12-12 | Michael Schmück | Antigen-specific CD4+ and CD8+ central-memory T cell preparations for adoptive T cell therapy |
US10421960B2 (en) | 2011-09-16 | 2019-09-24 | The Trustees Of The University Of Pennsylvania | RNA engineered T cells for the treatment of cancer |
WO2013166026A1 (en) | 2012-04-30 | 2013-11-07 | Allocure, Inc. | Methods of treating acute kidney injury using mesenchymal stem cells |
WO2014055657A1 (en) | 2012-10-05 | 2014-04-10 | The Trustees Of The University Of Pennsylvania | Use of a trans-signaling approach in chimeric antigen receptors |
US11091543B2 (en) * | 2015-05-07 | 2021-08-17 | Swedish Orphan Biovitrum Ag | Methods, compositions and dosing regimens for treating or preventing interferon-gamma related indications |
SG10201913604TA (en) | 2015-05-28 | 2020-02-27 | Kite Pharma Inc | Methods of conditioning patients for t cell therapy |
IL264502B2 (en) * | 2016-08-29 | 2023-09-01 | Tiziana Life Sciences Plc | Anti-cd3 antibody formulations |
CA3041434A1 (en) * | 2016-10-24 | 2018-05-03 | Novimmune Sa | Methods, compositions and dosing regimens for treating or preventing interferon-gamma related indications |
WO2018153984A1 (en) * | 2017-02-23 | 2018-08-30 | Universität Bern | Mtor inhibitor-corticoid combination therapy for multiple sclerosis |
WO2018183927A1 (en) | 2017-04-01 | 2018-10-04 | Avm Biotechnology, Llc | Replacement of cytotoxic preconditioning before cellular immunotherapy |
EP3488851A1 (en) | 2018-10-03 | 2019-05-29 | AVM Biotechnology, LLC | Immunoablative therapies |
-
2018
- 2018-10-03 EP EP18198491.5A patent/EP3488851A1/en not_active Withdrawn
- 2018-12-20 US US16/227,068 patent/US11446314B2/en active Active
-
2019
- 2019-10-03 EP EP19786713.8A patent/EP3860612A1/en active Pending
- 2019-10-03 US US17/281,016 patent/US12048705B2/en active Active
- 2019-10-03 WO PCT/US2019/054395 patent/WO2020072713A1/en unknown
- 2019-10-03 JP JP2019182659A patent/JP2020059703A/ja active Pending
- 2019-10-03 AU AU2019355004A patent/AU2019355004A1/en active Pending
- 2019-10-03 CN CN201980076619.1A patent/CN113164497A/zh active Pending
- 2019-10-03 MX MX2021003797A patent/MX2021003797A/es unknown
- 2019-10-03 SG SG11202103031SA patent/SG11202103031SA/en unknown
- 2019-10-03 KR KR1020217013417A patent/KR20210072039A/ko unknown
- 2019-10-03 BR BR112021006280A patent/BR112021006280A2/pt unknown
- 2019-10-03 CA CA3113969A patent/CA3113969A1/en active Pending
- 2019-10-03 ES ES19201254T patent/ES2863369T3/es active Active
- 2019-10-03 EA EA202190927A patent/EA202190927A1/ru unknown
-
2021
- 2021-04-23 ZA ZA2021/02727A patent/ZA202102727B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES2863369T3 (es) | 2021-10-11 |
US11446314B2 (en) | 2022-09-20 |
US20210338689A1 (en) | 2021-11-04 |
KR20210072039A (ko) | 2021-06-16 |
JP2020059703A (ja) | 2020-04-16 |
SG11202103031SA (en) | 2021-04-29 |
EP3860612A1 (en) | 2021-08-11 |
WO2020072713A1 (en) | 2020-04-09 |
ZA202102727B (en) | 2022-05-25 |
US20200108078A1 (en) | 2020-04-09 |
CA3113969A1 (en) | 2020-04-09 |
US12048705B2 (en) | 2024-07-30 |
EP3488851A1 (en) | 2019-05-29 |
AU2019355004A1 (en) | 2021-05-06 |
EA202190927A1 (ru) | 2021-08-02 |
CN113164497A (zh) | 2021-07-23 |
BR112021006280A2 (pt) | 2021-07-06 |
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