MX2018011696A - Composición farmacéutica de dapagliflozina. - Google Patents

Composición farmacéutica de dapagliflozina.

Info

Publication number
MX2018011696A
MX2018011696A MX2018011696A MX2018011696A MX2018011696A MX 2018011696 A MX2018011696 A MX 2018011696A MX 2018011696 A MX2018011696 A MX 2018011696A MX 2018011696 A MX2018011696 A MX 2018011696A MX 2018011696 A MX2018011696 A MX 2018011696A
Authority
MX
Mexico
Prior art keywords
dapagliflozin
pharmaceutical composition
stable pharmaceutical
premix
discloses
Prior art date
Application number
MX2018011696A
Other languages
English (en)
Inventor
Shervi Chandrakant
Panda Byomakesh
Krishna Bhavarisetti Murali
Das Subhasis
Kumar Thommandru Vijaya
Original Assignee
Lupin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lupin Ltd filed Critical Lupin Ltd
Publication of MX2018011696A publication Critical patent/MX2018011696A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención divulga una composición farmacéutica estable conformada por una premezcla de dapagliflozina con al menos un excipiente o excipientes farmacéuticamente aceptables, así como el proceso para su elaboración. La dapagliflozina es altamente higroscópica y, por lo tanto, es difícil formularla como una composición farmacéutica estable. La presente invención divulga una composición farmacéutica estable de dapagliflozina que comprende una premezcla de dapagliflozina con lactosa.
MX2018011696A 2016-03-31 2017-03-30 Composición farmacéutica de dapagliflozina. MX2018011696A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201621011351 2016-03-31
PCT/IB2017/051823 WO2017168360A1 (en) 2016-03-31 2017-03-30 Pharmaceutical composition of dapagliflozin

Publications (1)

Publication Number Publication Date
MX2018011696A true MX2018011696A (es) 2019-06-06

Family

ID=58549178

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018011696A MX2018011696A (es) 2016-03-31 2017-03-30 Composición farmacéutica de dapagliflozina.

Country Status (8)

Country Link
US (1) US20190110994A1 (es)
EP (1) EP3435987A1 (es)
JP (1) JP2019512537A (es)
BR (1) BR112018069782A2 (es)
MX (1) MX2018011696A (es)
PH (1) PH12018502089A1 (es)
WO (1) WO2017168360A1 (es)
ZA (1) ZA201807125B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11020412B2 (en) 2017-03-16 2021-06-01 Inventia Healthcare Limited Pharmaceutical composition comprising dapagliflozin
US20230033410A1 (en) * 2019-12-24 2023-02-02 Hanmi Pharm. Co.,Ltd. Complex formulation comprising sitagliptin and dapagliflozin, and preparation method therefor
TR202004809A2 (tr) * 2020-03-27 2021-10-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Metformi̇n ve dapagli̇flozi̇n i̇çeren bi̇r saşe formülasyonu
WO2022119543A1 (en) * 2020-12-03 2022-06-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi A process for tablet formulations comprising amorphous dapagliflozin and metformin hydrochloride

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515117B2 (en) 1999-10-12 2003-02-04 Bristol-Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
US7919598B2 (en) 2006-06-28 2011-04-05 Bristol-Myers Squibb Company Crystal structures of SGLT2 inhibitors and processes for preparing same
SI2498758T1 (sl) * 2009-11-13 2018-10-30 Astrazeneca Ab Formulacije dvoplastnih tablet
JP5837072B2 (ja) * 2010-09-03 2015-12-24 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 水溶性抗酸化剤を使用する製剤
CA2837232A1 (en) 2011-06-03 2012-12-06 Ratiopharm Gmbh Pharmaceutical composition comprising dapagliflozin and cyclodextrin
WO2014178040A1 (en) * 2013-04-29 2014-11-06 Mapi Pharma Ltd. Co-crystals of dapagliflozin
WO2015128853A1 (en) * 2014-02-28 2015-09-03 Sun Pharmaceutical Industries Limited Dapagliflozin compositions

Also Published As

Publication number Publication date
ZA201807125B (en) 2019-08-28
WO2017168360A1 (en) 2017-10-05
BR112018069782A2 (pt) 2019-01-29
US20190110994A1 (en) 2019-04-18
PH12018502089A1 (en) 2019-07-15
JP2019512537A (ja) 2019-05-16
EP3435987A1 (en) 2019-02-06

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