MX2016010345A - Celulas para inmunoterapia diseñadas para dirigir antigeno presente tanto en celulas inmunes y celulas patologicas. - Google Patents

Celulas para inmunoterapia diseñadas para dirigir antigeno presente tanto en celulas inmunes y celulas patologicas.

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Publication number
MX2016010345A
MX2016010345A MX2016010345A MX2016010345A MX2016010345A MX 2016010345 A MX2016010345 A MX 2016010345A MX 2016010345 A MX2016010345 A MX 2016010345A MX 2016010345 A MX2016010345 A MX 2016010345A MX 2016010345 A MX2016010345 A MX 2016010345A
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MX
Mexico
Prior art keywords
cells
pathological
immune cells
antigen present
immunotherapy
Prior art date
Application number
MX2016010345A
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English (en)
Inventor
Poirot Laurent
Duchateau Philippe
Original Assignee
Cellectis
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50114255&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2016010345(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cellectis filed Critical Cellectis
Publication of MX2016010345A publication Critical patent/MX2016010345A/es

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    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
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    • A61K39/4643—Vertebrate antigens
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    • A61K39/464402—Receptors, cell surface antigens or cell surface determinants
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    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464436—Cytokines
    • A61K39/464438—Tumor necrosis factors [TNF], CD70
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    • C12N9/14—Hydrolases (3)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Métodos de desarrollo de células inmune diseñados genéticamente para inmunoterapia, las cuales se encuentran dotadas con Receptores de Antígenos Quiméricos que dirigen un marcador de antígeno que es común tanto para las células patológicas y las células inmunes (ejemplo: CD38, CS1 o CD70) por el hecho de que los genes que dosifican los marcadores están inactivos en las células inmune por una endonucleasa de corte poco frecuente tal como TALEN, Cas9 o argonauta.
MX2016010345A 2014-02-14 2015-02-13 Celulas para inmunoterapia diseñadas para dirigir antigeno presente tanto en celulas inmunes y celulas patologicas. MX2016010345A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201470076 2014-02-14
PCT/EP2015/053162 WO2015121454A1 (en) 2014-02-14 2015-02-13 Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells

Publications (1)

Publication Number Publication Date
MX2016010345A true MX2016010345A (es) 2017-01-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016010345A MX2016010345A (es) 2014-02-14 2015-02-13 Celulas para inmunoterapia diseñadas para dirigir antigeno presente tanto en celulas inmunes y celulas patologicas.

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Country Link
US (3) US10836998B2 (es)
EP (2) EP3505623A1 (es)
JP (1) JP6673838B2 (es)
KR (1) KR102157924B1 (es)
CN (1) CN106029875A (es)
AU (1) AU2015216875B2 (es)
BR (1) BR112016017806B1 (es)
CA (1) CA2937711C (es)
DK (1) DK3105317T3 (es)
ES (1) ES2711498T3 (es)
HU (1) HUE041497T2 (es)
IL (1) IL246645B (es)
MX (1) MX2016010345A (es)
NO (1) NO20161276A1 (es)
PL (1) PL3105317T3 (es)
PT (1) PT3105317T (es)
RU (1) RU2714258C2 (es)
TR (1) TR201819571T4 (es)
WO (1) WO2015121454A1 (es)

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