MX2007003506A - Terapia de combinacion de cancer que comprende azd2171 e imatinib. - Google Patents

Terapia de combinacion de cancer que comprende azd2171 e imatinib.

Info

Publication number
MX2007003506A
MX2007003506A MX2007003506A MX2007003506A MX2007003506A MX 2007003506 A MX2007003506 A MX 2007003506A MX 2007003506 A MX2007003506 A MX 2007003506A MX 2007003506 A MX2007003506 A MX 2007003506A MX 2007003506 A MX2007003506 A MX 2007003506A
Authority
MX
Mexico
Prior art keywords
azd2171
imatinib
human
combination therapy
cancer
Prior art date
Application number
MX2007003506A
Other languages
English (en)
Inventor
Stephen Robert Wedge
Original Assignee
Aztrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0421436A external-priority patent/GB0421436D0/en
Priority claimed from GB0506725A external-priority patent/GB0506725D0/en
Application filed by Aztrazeneca Ab filed Critical Aztrazeneca Ab
Publication of MX2007003506A publication Critical patent/MX2007003506A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion se relaciona a un metodo para la produccion de un efecto que reduce la permeabilidad antiangiogenica y/o vascular en un animal de sangre caliente, tal como un ser humano, el cual esta siendo tratado opcionalmente con radiacion ionizante, particularmente un metodo para el tratamiento de cancer, particularmente un cancer que implica un tumor solido o una leucemia, el cual comprende la administracion de AZD2171 en combinacion imatinib; a una composicion farmaceutica que comprende AZD2171 e imatinib; a un producto de combinacion que comprende AZD2171 e imatinib para el uso en un metodo de tratamiento de un cuerpo humano o animal por terapia; a un equipo que comprende AZD2171 e imatinib; al uso de AZD2171 e imatinib en la fabricacion de un medicamento para uso en la produccion de un efecto que reduce la permeabilidad antiangiogenica y/o vascular en un animal de sangre caliente tal como un ser humano el cual esta siendo opcionalmente tratado con radiacion ionizante.
MX2007003506A 2004-09-27 2005-09-23 Terapia de combinacion de cancer que comprende azd2171 e imatinib. MX2007003506A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0421436A GB0421436D0 (en) 2004-09-27 2004-09-27 Combination therapy
GB0506725A GB0506725D0 (en) 2005-04-01 2005-04-01 Combination therapy
PCT/GB2005/003672 WO2006035203A1 (en) 2004-09-27 2005-09-23 Cancer combination therapy comprising azd2171 and imatinib

Publications (1)

Publication Number Publication Date
MX2007003506A true MX2007003506A (es) 2007-05-10

Family

ID=35355143

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007003506A MX2007003506A (es) 2004-09-27 2005-09-23 Terapia de combinacion de cancer que comprende azd2171 e imatinib.

Country Status (11)

Country Link
US (2) US20080015205A1 (es)
EP (1) EP1796672A1 (es)
JP (1) JP2008514576A (es)
KR (1) KR20070073813A (es)
AU (1) AU2005288736B2 (es)
BR (1) BRPI0516024A (es)
CA (1) CA2579067A1 (es)
IL (1) IL181608A0 (es)
MX (1) MX2007003506A (es)
NO (1) NO20071426L (es)
WO (1) WO2006035203A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0008269D0 (en) * 2000-04-05 2000-05-24 Astrazeneca Ab Combination chemotherapy
GB0310401D0 (en) * 2003-05-07 2003-06-11 Astrazeneca Ab Therapeutic agent
EP1740170A2 (en) * 2004-03-23 2007-01-10 AstraZeneca AB Combination therapy with azd2171 and platinum anti-tumour agent
GB0406445D0 (en) * 2004-03-23 2004-04-28 Astrazeneca Ab Combination therapy
GB0406446D0 (en) * 2004-03-23 2004-04-28 Astrazeneca Ab Combination therapy
MX2007003505A (es) * 2004-09-27 2007-05-10 Astrazeneca Ab Combinacion que comprende zd6474 e imatinib.
JP2009500384A (ja) * 2005-07-06 2009-01-08 アストラゼネカ アクチボラグ 併用療法
AU2006328201B2 (en) * 2005-12-22 2010-08-19 Astrazeneca Ab Combination of AZD2171 and pemetrexed
MX2013011199A (es) * 2011-04-01 2013-12-16 Threshold Pharmaceuticals Inc Metodos para tratar el cancer.
KR101386697B1 (ko) * 2012-06-18 2014-04-18 아주대학교산학협력단 이매티닙 또는 이의 약학적으로 허용되는 염을 유효성분으로 포함하는 혈관 투과성 관련 질환의 치료 또는 예방용 조성물
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
KR102277833B1 (ko) 2013-02-20 2021-07-14 칼라 파마슈티컬스, 인크. 치료 화합물 및 그의 용도
AU2014296032A1 (en) 2013-07-31 2016-03-17 Windward Pharma, Inc. Aerosol tyrosine kinase inhibitor compounds and uses thereof
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
MX355330B (es) 2013-11-01 2018-04-16 Kala Pharmaceuticals Inc Formas cristalinas de compuestos terapeuticos y sus usos.
WO2015069489A1 (en) 2013-11-06 2015-05-14 Merck Patent Gmbh Predictive biomarker for hypoxia-activated prodrug therapy
AU2017221268B2 (en) * 2016-02-15 2024-02-15 Astrazeneca Ab Methods comprising fixed intermittent dosing of cediranib
AU2017324251A1 (en) 2016-09-08 2019-03-21 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
EP3509423A4 (en) 2016-09-08 2020-05-13 Kala Pharmaceuticals, Inc. CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF
US10253036B2 (en) 2016-09-08 2019-04-09 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100838617B1 (ko) * 1999-02-10 2008-06-16 아스트라제네카 아베 혈관형성 억제제로서의 퀴나졸린 유도체
JP2004043390A (ja) * 2002-07-12 2004-02-12 Nagoya Industrial Science Research Inst 抗腫瘍剤
EA013811B1 (ru) * 2002-11-21 2010-08-30 Новартис Вэксинес Энд Дайэгностикс, Инк. 2,4,6-тризамещённые пиримидины, являющиеся ингибиторами фосфотидилинозитол(pi)-3-киназы, и их применение при лечении рака
GB2398565A (en) * 2003-02-18 2004-08-25 Cipla Ltd Imatinib preparation and salts
KR20060097000A (ko) * 2003-09-23 2006-09-13 노파르티스 아게 화학요법제와 vegf 수용체 저해제의 배합물

Also Published As

Publication number Publication date
AU2005288736A1 (en) 2006-04-06
NO20071426L (no) 2007-06-18
IL181608A0 (en) 2007-07-04
KR20070073813A (ko) 2007-07-10
BRPI0516024A (pt) 2008-08-19
WO2006035203A1 (en) 2006-04-06
EP1796672A1 (en) 2007-06-20
AU2005288736B2 (en) 2008-08-14
JP2008514576A (ja) 2008-05-08
US20090325977A1 (en) 2009-12-31
US20080015205A1 (en) 2008-01-17
CA2579067A1 (en) 2006-04-06

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal