ME00563A - Process for preparing optically pure active compounds - Google Patents

Process for preparing optically pure active compounds

Info

Publication number
ME00563A
ME00563A MEP-848/08A MEP84808A ME00563A ME 00563 A ME00563 A ME 00563A ME P84808 A MEP84808 A ME P84808A ME 00563 A ME00563 A ME 00563A
Authority
ME
Montenegro
Prior art keywords
optically pure
active compounds
pure active
preparing optically
chiral
Prior art date
Application number
MEP-848/08A
Other languages
Bosnian (bs)
English (en)
Inventor
Bernhard Kohl
Bernd Mueller
Ralf Steffen Weingart
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of ME00563A publication Critical patent/ME00563A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)
  • Catalysts (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
MEP-848/08A 2002-12-06 2003-12-03 Process for preparing optically pure active compounds ME00563A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP02027273 2002-12-06
DE10340255 2003-08-29
YU20050423A RS52667B (en) 2002-12-06 2003-12-03 PROCEDURE FOR PREPARING OPTICALLY CLEAN UNITS
PCT/EP2003/013605 WO2004052882A1 (en) 2002-12-06 2003-12-03 Process for preparing optically pure active compounds

Publications (1)

Publication Number Publication Date
ME00563A true ME00563A (en) 2011-12-20

Family

ID=32509784

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-848/08A ME00563A (en) 2002-12-06 2003-12-03 Process for preparing optically pure active compounds

Country Status (28)

Country Link
US (1) US7452998B2 (ko)
EP (1) EP1578742B1 (ko)
JP (1) JP4612542B2 (ko)
KR (1) KR101062806B1 (ko)
CN (1) CN100482658C (ko)
AR (1) AR042277A1 (ko)
AU (1) AU2003289948B2 (ko)
BR (2) BR0317005A (ko)
CA (1) CA2507807C (ko)
CY (1) CY1114058T1 (ko)
DK (1) DK1578742T3 (ko)
EA (1) EA011771B1 (ko)
ES (1) ES2397380T3 (ko)
HK (1) HK1078864A1 (ko)
HR (1) HRP20050604B1 (ko)
IL (1) IL168456A (ko)
IS (1) IS2885B (ko)
ME (1) ME00563A (ko)
MX (1) MXPA05005762A (ko)
NO (1) NO330978B1 (ko)
NZ (1) NZ540815A (ko)
PL (1) PL375818A1 (ko)
PT (1) PT1578742E (ko)
RS (1) RS52667B (ko)
SI (1) SI1578742T1 (ko)
TW (1) TWI313268B (ko)
WO (1) WO2004052882A1 (ko)
ZA (1) ZA200503543B (ko)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2384160T3 (es) 1999-01-13 2012-07-02 Bayer Healthcare Llc Difenil ureas sustituidas con omega-carboxi arilo como agentes inhibidores de la cinasa p38
DK1575941T3 (da) 2002-12-06 2012-07-09 Nycomed Gmbh Fremgangsmåde til fremstilling af (S)-pantoprazol
FR2848555B1 (fr) * 2002-12-16 2006-07-28 Negma Gild Enantiomere(-)du tenatoprazole et son application en therapeutique
JP2006514108A (ja) * 2002-12-19 2006-04-27 テバ ファーマシューティカル インダストリーズ リミティド パントプラゾールナトリウムの固体状態、それらの調製方法、及び公知のパントプラゾールナトリウム水和物の調製方法
US7683177B2 (en) * 2003-06-10 2010-03-23 Teva Pharmaceutical Industries Ltd Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
MXPA06013623A (es) * 2004-06-02 2007-02-28 Altana Pharma Ag Procedimiento para la preparacion de compuestos piridin-2-ilmetilsulfinil-1h-benzimidazol.
FR2871800B1 (fr) * 2004-06-17 2006-08-25 Sidem Pharma Sa Sa Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
AU2005257709C1 (en) * 2004-06-24 2011-02-24 Astrazeneca Ab New process for the preparation of crystal modifications for use in the preparation of esomeprazole sodium salt
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
US7579476B2 (en) * 2006-02-24 2009-08-25 Praktikatalyst Pharma, Llc Transition metal mediated oxidation of hetero atoms in organic molecules coordinated to transition metals
WO2008018091A1 (en) * 2006-08-08 2008-02-14 Jubilant Organosys Limited Process for producing sulphoxide compounds
WO2008047681A1 (fr) 2006-10-13 2008-04-24 Eisai R & D Management Co., Ltd. Benzimidazole présentant une activité inhibitrice de la sécrétion d'acide gastrique
US20080103169A1 (en) 2006-10-27 2008-05-01 The Curators Of The University Of Missouri Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
CA2717578A1 (en) * 2008-03-18 2009-09-24 Dr. Reddy's Laboratories Ltd. Dexlansoprazole process and polymorphs
EP2143722A1 (en) 2008-07-09 2010-01-13 Lek Pharmaceuticals D.D. Process for preparation of esomeprazole sodium of high chemical purity and new forms of esomeprazole sodium
EP2264024A1 (en) 2008-10-14 2010-12-22 LEK Pharmaceuticals d.d. Process for the preparation of enantiomerically enriched proton pump inhibitors
US8071781B2 (en) * 2008-11-11 2011-12-06 Syn-Tech Chem. & Pharm. Co., Ltd. Process for preparing rabeprazole sodium
CA2789298A1 (en) 2010-02-12 2011-08-18 Esteve Quimica, S.A. Preparation process of the sodium salt of esomeprazole
CN103113351B (zh) * 2013-03-08 2015-01-21 苏州特瑞药业有限公司 一种光学纯手性亚砜类化合物的制备方法
CN103936714A (zh) * 2014-04-15 2014-07-23 北京华禧联合科技发展有限公司 一种埃索美拉唑镁的制备方法
KR20170098843A (ko) * 2014-12-26 2017-08-30 고쿠리츠다이가쿠호우진 도쿄다이가쿠 광학 활성의 프로톤 펌프 저해 화합물의 제조 방법
CN105440018A (zh) * 2015-11-27 2016-03-30 福州闽海药业有限公司 一种锆催化的右旋兰索拉唑的不对称氧化合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
IL75400A (en) 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
FI90544C (fi) 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
SE465514B (sv) 1990-02-19 1991-09-23 Curt Pettersson Foerfarande och anvaendning av ett separationsmedium vid separation av enantiomerer
DE4035455A1 (de) 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
JPH08509736A (ja) 1993-04-27 1996-10-15 セプラコー,インコーポレイテッド 光学的に純粋な(−)パントプラゾールを用いる胃の疾患治療の方法と組成
CA2161130A1 (en) 1993-04-27 1994-11-10 Nancy M. Gray Methods and compositions for treating gastric disorders using optically pure (+) pantoprazole
SE9301830D0 (sv) 1993-05-28 1993-05-28 Ab Astra New compounds
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
GB9423968D0 (en) 1994-11-28 1995-01-11 Astra Ab Resolution
GB9423970D0 (en) 1994-11-28 1995-01-11 Astra Ab Oxidation
HRP960232A2 (en) 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
DK1575941T3 (da) 2002-12-06 2012-07-09 Nycomed Gmbh Fremgangsmåde til fremstilling af (S)-pantoprazol

Also Published As

Publication number Publication date
JP4612542B2 (ja) 2011-01-12
CA2507807C (en) 2013-10-22
KR101062806B1 (ko) 2011-09-07
MXPA05005762A (es) 2005-08-16
HRP20050604A2 (en) 2006-09-30
HK1078864A1 (en) 2006-03-24
EP1578742A1 (en) 2005-09-28
EA011771B1 (ru) 2009-06-30
CN1717403A (zh) 2006-01-04
TW200508219A (en) 2005-03-01
AU2003289948B2 (en) 2009-12-24
NO20053099L (no) 2005-06-24
SI1578742T1 (sl) 2013-02-28
DK1578742T3 (da) 2013-01-21
WO2004052882A1 (en) 2004-06-24
US20050288334A1 (en) 2005-12-29
NO20053099D0 (no) 2005-06-24
EA200500898A1 (ru) 2005-12-29
BRPI0310118B1 (pt) 2015-10-20
AR042277A1 (es) 2005-06-15
JP2006516261A (ja) 2006-06-29
IL168456A (en) 2012-02-29
RS20050423A (en) 2007-04-10
ES2397380T3 (es) 2013-03-06
NO330978B1 (no) 2011-08-29
EP1578742B1 (en) 2012-10-17
PT1578742E (pt) 2013-01-24
KR20050085224A (ko) 2005-08-29
IS2885B (is) 2014-07-15
CY1114058T1 (el) 2016-07-27
ZA200503543B (en) 2006-08-30
BR0317005A (pt) 2005-10-25
PL375818A1 (en) 2005-12-12
TWI313268B (en) 2009-08-11
CA2507807A1 (en) 2004-06-24
CN100482658C (zh) 2009-04-29
HRP20050604B1 (hr) 2013-09-30
IS7909A (is) 2005-06-23
US7452998B2 (en) 2008-11-18
RS52667B (en) 2013-06-28
AU2003289948A1 (en) 2004-06-30
NZ540815A (en) 2008-03-28

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