MA46642A - Promédicaments d'inhibiteurs de la kallicréine - Google Patents
Promédicaments d'inhibiteurs de la kallicréineInfo
- Publication number
- MA46642A MA46642A MA046642A MA46642A MA46642A MA 46642 A MA46642 A MA 46642A MA 046642 A MA046642 A MA 046642A MA 46642 A MA46642 A MA 46642A MA 46642 A MA46642 A MA 46642A
- Authority
- MA
- Morocco
- Prior art keywords
- kallicrein
- medicinal products
- inhibitor
- inhibitor medicinal
- products
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662415202P | 2016-10-31 | 2016-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA46642A true MA46642A (fr) | 2021-04-21 |
Family
ID=62025466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA046642A MA46642A (fr) | 2016-10-31 | 2017-10-27 | Promédicaments d'inhibiteurs de la kallicréine |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10759759B2 (https=) |
| EP (1) | EP3532057B1 (https=) |
| JP (1) | JP7128181B2 (https=) |
| AU (1) | AU2017348305B2 (https=) |
| CA (1) | CA3041058A1 (https=) |
| DK (1) | DK3532057T3 (https=) |
| ES (1) | ES2942285T3 (https=) |
| IL (1) | IL266223B2 (https=) |
| MA (1) | MA46642A (https=) |
| WO (1) | WO2018081513A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017348305B2 (en) | 2016-10-31 | 2022-04-21 | Biocryst Pharmaceuticals, Inc. | Prodrugs of kallikrein inhibitors |
| JP7668227B2 (ja) | 2019-04-08 | 2025-04-24 | バイオクライスト ファーマシューティカルズ， インコーポレイテッド | 血漿カリクレイン阻害剤および眼障害におけるその使用方法 |
| AU2021288365B2 (en) * | 2020-06-12 | 2023-07-06 | Apical Molecular Biotech. Co., Ltd. | Novel analogs of pterostilbene amino acid bearing carbonates for treating a non-alcoholic fatty liver disease and nonalcoholic steatohepatitis |
| CN111646936A (zh) * | 2020-06-22 | 2020-09-11 | 江苏亚虹医药科技有限公司 | 芳香醚类化合物的制备方法 |
| CN114933584B (zh) * | 2021-08-09 | 2022-12-27 | 上海贵之言医药科技有限公司 | 一种二氢-2h-异吲哚酯类化合物 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4559157A (en) | 1983-04-21 | 1985-12-17 | Creative Products Resource Associates, Ltd. | Cosmetic applicator useful for skin moisturizing |
| LU84979A1 (fr) | 1983-08-30 | 1985-04-24 | Oreal | Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux |
| LU86084A1 (fr) | 1985-09-20 | 1987-04-02 | Faco Sa | Apparei de massage electrique |
| US5102417A (en) | 1985-11-07 | 1992-04-07 | Expandable Grafts Partnership | Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft |
| US4800882A (en) | 1987-03-13 | 1989-01-31 | Cook Incorporated | Endovascular stent and delivery system |
| US4820508A (en) | 1987-06-23 | 1989-04-11 | Neutrogena Corporation | Skin protective composition |
| US4886062A (en) | 1987-10-19 | 1989-12-12 | Medtronic, Inc. | Intravascular radially expandable stent and method of implant |
| US4992478A (en) | 1988-04-04 | 1991-02-12 | Warner-Lambert Company | Antiinflammatory skin moisturizing composition and method of preparing same |
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| WO1990013332A1 (en) | 1989-05-11 | 1990-11-15 | Cedars-Sinai Medical Center | Stent with sustained drug delivery |
| CA2049973C (en) | 1990-02-28 | 2002-12-24 | Rodney G. Wolff | Intralumenal drug eluting prosthesis |
| US5429634A (en) | 1993-09-09 | 1995-07-04 | Pdt Systems | Biogenic implant for drug delivery and method |
| US5419760A (en) | 1993-01-08 | 1995-05-30 | Pdt Systems, Inc. | Medicament dispensing stent for prevention of restenosis of a blood vessel |
| US6774278B1 (en) | 1995-06-07 | 2004-08-10 | Cook Incorporated | Coated implantable medical device |
| MXPA03009130A (es) * | 2000-10-20 | 2004-02-26 | Biocryst Pharm Inc | Compuestos de biarilo que funcionan como inhibidores de proteasa serina. |
| RU2003132706A (ru) | 2001-04-06 | 2005-04-20 | Байокрист Фармасьютикалз, Инк. (Us) | Диариловые соединения в качестве ингибиторов сериновых протеаз |
| WO2004002985A1 (en) | 2002-06-27 | 2004-01-08 | Lg Life Sciences Ltd. | Peptidic thrombin inhibitor compound |
| US6770729B2 (en) | 2002-09-30 | 2004-08-03 | Medtronic Minimed, Inc. | Polymer compositions containing bioactive agents and methods for their use |
| GB0301938D0 (en) | 2003-01-28 | 2003-02-26 | Biochemie Gmbh | Organic compounds |
| DK2070536T3 (da) | 2006-10-06 | 2012-04-10 | Toyama Chemical Co Ltd | Farmaceutisk sammensætning med et phenylamidin-derivat og fremgangsmåde til anvendelse af den farmaceutiske sammensætning i kombination med et antifungalt middel |
| KR20100026641A (ko) | 2008-09-01 | 2010-03-10 | 동아제약주식회사 | 신규한 벤즈아미드 유도체 화합물 및 그의 제조방법 |
| WO2012137225A1 (en) | 2011-04-08 | 2012-10-11 | Sphaera Pharma Pvt. Ltd | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds |
| ES2883259T3 (es) | 2011-07-28 | 2021-12-07 | Kempharm Inc | Profármacos de metilfenidato, procesos para la obtención y uso de los mismos |
| TWI601725B (zh) | 2012-08-27 | 2017-10-11 | 加拓科學公司 | 取代的氮雜吲哚化合物及其鹽、組合物和用途 |
| US9868690B2 (en) | 2012-12-21 | 2018-01-16 | Ratiopharm Gmbh | Prodrugs of monomethyl fumarate (MMF) |
| EP3046924A1 (en) | 2013-09-20 | 2016-07-27 | IDENIX Pharmaceuticals, Inc. | Hepatitis c virus inhibitors |
| RU2733405C2 (ru) | 2014-02-07 | 2020-10-01 | Экзитера Фармасьютикалз Инк. | Терапевтические соединения и композиции |
| US10905683B2 (en) | 2014-08-22 | 2021-02-02 | Biocryst Pharmaceuticals, Inc. | Compositions and uses of amidine derivatives |
| WO2016029216A2 (en) * | 2014-08-22 | 2016-02-25 | Biocryst Pharmaceuticals, Inc. | Method for producing amidine derivatives |
| AU2017348305B2 (en) | 2016-10-31 | 2022-04-21 | Biocryst Pharmaceuticals, Inc. | Prodrugs of kallikrein inhibitors |
-
2017
- 2017-10-27 AU AU2017348305A patent/AU2017348305B2/en active Active
- 2017-10-27 ES ES17864949T patent/ES2942285T3/es active Active
- 2017-10-27 CA CA3041058A patent/CA3041058A1/en active Pending
- 2017-10-27 IL IL266223A patent/IL266223B2/en unknown
- 2017-10-27 JP JP2019522794A patent/JP7128181B2/ja active Active
- 2017-10-27 MA MA046642A patent/MA46642A/fr unknown
- 2017-10-27 US US16/345,503 patent/US10759759B2/en active Active
- 2017-10-27 WO PCT/US2017/058685 patent/WO2018081513A1/en not_active Ceased
- 2017-10-27 DK DK17864949.7T patent/DK3532057T3/da active
- 2017-10-27 EP EP17864949.7A patent/EP3532057B1/en active Active
-
2020
- 2020-08-07 US US16/987,721 patent/US11618731B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL266223B1 (en) | 2023-12-01 |
| JP2019535688A (ja) | 2019-12-12 |
| US11618731B2 (en) | 2023-04-04 |
| DK3532057T3 (da) | 2023-02-20 |
| JP7128181B2 (ja) | 2022-08-30 |
| IL266223B2 (en) | 2024-04-01 |
| CA3041058A1 (en) | 2018-05-03 |
| EP3532057A4 (en) | 2020-07-01 |
| ES2942285T3 (es) | 2023-05-31 |
| US10759759B2 (en) | 2020-09-01 |
| EP3532057A1 (en) | 2019-09-04 |
| AU2017348305B2 (en) | 2022-04-21 |
| AU2017348305A1 (en) | 2019-05-30 |
| WO2018081513A1 (en) | 2018-05-03 |
| US20190382344A1 (en) | 2019-12-19 |
| IL266223A (en) | 2019-06-30 |
| US20210198204A1 (en) | 2021-07-01 |
| EP3532057B1 (en) | 2022-12-21 |
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