MA28653B1 - Nouveaux derives fluoroglycosidiques des pyrazoles, les medicaments contenant ces composes et leur utilisation - Google Patents
Nouveaux derives fluoroglycosidiques des pyrazoles, les medicaments contenant ces composes et leur utilisationInfo
- Publication number
- MA28653B1 MA28653B1 MA29515A MA29515A MA28653B1 MA 28653 B1 MA28653 B1 MA 28653B1 MA 29515 A MA29515 A MA 29515A MA 29515 A MA29515 A MA 29515A MA 28653 B1 MA28653 B1 MA 28653B1
- Authority
- MA
- Morocco
- Prior art keywords
- compounds
- pyrazoles
- new
- products containing
- medicinal products
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 150000003217 pyrazoles Chemical class 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- NOIXNOMHHWGUTG-UHFFFAOYSA-N 2-[[4-[4-pyridin-4-yl-1-(2,2,2-trifluoroethyl)pyrazol-3-yl]phenoxy]methyl]quinoline Chemical compound C=1C=C(OCC=2N=C3C=CC=CC3=CC=2)C=CC=1C1=NN(CC(F)(F)F)C=C1C1=CC=NC=C1 NOIXNOMHHWGUTG-UHFFFAOYSA-N 0.000 abstract 1
- 239000003472 antidiabetic agent Substances 0.000 abstract 1
- 229940125708 antidiabetic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
Abstract
Nouveaux dérivés fluoroglycosidiques des pyrazoles, les médicaments contenant ces composés et leur utilisation. L'invention concerne des dérivés fluoroglycosidiques substitués des pyrazoles de formule (I), dans laquelle les radicaux ont les significations indiquées, les sels physiologiquement compatibles de ceux-ci, et une méthode de production de ceux-ci. Les composés conviennent par exemple en tant qu'antidiabétiques.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004028241A DE102004028241B4 (de) | 2004-06-11 | 2004-06-11 | Neue Fluorglykosidderivate von Pyrazolen, diese Verbindungen enthaltende Arzneimittel und Herstellung dieser Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
MA28653B1 true MA28653B1 (fr) | 2007-06-01 |
Family
ID=35355753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA29515A MA28653B1 (fr) | 2004-06-11 | 2006-12-05 | Nouveaux derives fluoroglycosidiques des pyrazoles, les medicaments contenant ces composes et leur utilisation |
Country Status (34)
Country | Link |
---|---|
US (1) | US7820804B2 (fr) |
EP (1) | EP1758914B1 (fr) |
JP (1) | JP4996464B2 (fr) |
CN (1) | CN100582116C (fr) |
AR (1) | AR049393A1 (fr) |
AU (1) | AU2005252329B2 (fr) |
BR (1) | BRPI0510770A (fr) |
CA (1) | CA2570042C (fr) |
CR (1) | CR8773A (fr) |
CY (1) | CY1107426T1 (fr) |
DE (2) | DE102004028241B4 (fr) |
DK (1) | DK1758914T3 (fr) |
EC (1) | ECSP067054A (fr) |
ES (1) | ES2296180T3 (fr) |
HK (1) | HK1100411A1 (fr) |
HR (1) | HRP20080023T3 (fr) |
IL (1) | IL179757A (fr) |
MA (1) | MA28653B1 (fr) |
MX (1) | MXPA06013513A (fr) |
MY (1) | MY143565A (fr) |
NO (1) | NO20070176L (fr) |
NZ (1) | NZ551948A (fr) |
PE (1) | PE20060297A1 (fr) |
PL (1) | PL1758914T3 (fr) |
PT (1) | PT1758914E (fr) |
RS (1) | RS50541B (fr) |
RU (1) | RU2370499C2 (fr) |
SI (1) | SI1758914T1 (fr) |
TN (1) | TNSN06409A1 (fr) |
TW (1) | TWI382030B (fr) |
UA (1) | UA89787C2 (fr) |
UY (1) | UY28955A1 (fr) |
WO (1) | WO2005121161A1 (fr) |
ZA (1) | ZA200608832B (fr) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200637869A (en) | 2005-01-28 | 2006-11-01 | Chugai Pharmaceutical Co Ltd | The spiroketal derivatives and the use as therapeutical agent for diabetes of the same |
DE102005026762A1 (de) | 2005-06-09 | 2006-12-21 | Sanofi-Aventis Deutschland Gmbh | Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen |
PE20110235A1 (es) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | Combinaciones farmaceuticas que comprenden linagliptina y metmorfina |
JP5067644B2 (ja) | 2006-05-19 | 2012-11-07 | 大正製薬株式会社 | C−フェニルグリシト−ル化合物 |
CN101479254B (zh) | 2006-06-29 | 2012-05-30 | 大正制药株式会社 | C-苯基1-硫代山梨醇化合物 |
BRPI0715160A2 (pt) | 2006-08-08 | 2013-06-11 | Sanofi Aventis | imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso |
DE102006053637B4 (de) | 2006-11-14 | 2011-06-30 | Sanofi-Aventis Deutschland GmbH, 65929 | Neue mit Fluor substituierte 1,4-Benzothiepin-1,1-Dioxidderivate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
WO2008072726A1 (fr) | 2006-12-14 | 2008-06-19 | Taisho Pharmaceutical Co., Ltd. | Dérivé de 1-phényl 1-thio-d-glucitol |
EP2025674A1 (fr) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament |
JP5272395B2 (ja) * | 2007-12-12 | 2013-08-28 | セントラル硝子株式会社 | 4−デオキシ−4−フルオロ−d−グルコース誘導体の製造方法 |
TW201014822A (en) | 2008-07-09 | 2010-04-16 | Sanofi Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
BRPI0918841B8 (pt) * | 2008-08-28 | 2021-05-25 | Pfizer | derivados de dioxa-biciclo[3.2.1]octano-2,3,4-triol, seus cristais, composições farmacêuticas e usos |
WO2010068601A1 (fr) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | Hydrate de fluoroglycoside hétéroaromatique cristallin, ses procédés de fabrication, ses procédés d'utilisation et compositions pharmaceutiques le contenant |
TWI460187B (zh) | 2009-02-23 | 2014-11-11 | 大正製藥股份有限公司 | 4-異丙基苯基葡萄糖醇化合物 |
CN102482312A (zh) * | 2009-08-26 | 2012-05-30 | 赛诺菲 | 新颖的杂芳族氟代糖苷结晶水合物、含有这些化合物的药物和它们的用途 |
EP2298782A1 (fr) | 2009-08-26 | 2011-03-23 | Sanofi-Aventis | Procédé de synthèse de dérivé de type pyrazole glucoside |
KR20120091174A (ko) | 2009-10-02 | 2012-08-17 | 사노피 | 골질환 치료제의 제조를 위한 sglt-1/sglt-2 억제제 활성을 갖는 화합물의 용도 |
US8163704B2 (en) | 2009-10-20 | 2012-04-24 | Novartis Ag | Glycoside derivatives and uses thereof |
AP3099A (en) | 2009-11-02 | 2015-01-31 | Pfizer | Dioxa-bicyclo[3.2.1]octane-2,3,4-triol de derivatives |
US20120294936A1 (en) | 2009-11-13 | 2012-11-22 | Astrazeneca Uk Limited | Reduced mass metformin formulations |
ES2689107T3 (es) | 2009-11-13 | 2018-11-08 | Astrazeneca Ab | Formulaciones de tabletas bicapa |
JP5784623B2 (ja) | 2009-11-13 | 2015-09-24 | アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag | 速放性錠剤製剤 |
WO2011107494A1 (fr) | 2010-03-03 | 2011-09-09 | Sanofi | Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation |
EP2582709B1 (fr) | 2010-06-18 | 2018-01-24 | Sanofi | Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
JP5656092B2 (ja) | 2010-08-20 | 2015-01-21 | 大正製薬株式会社 | 4−イソプロピルフェニルグルシトール化合物の結晶形及びその製造方法 |
US9161945B2 (en) | 2010-08-20 | 2015-10-20 | Taisho Pharmaceutical Co., Ltd. | 4-isopropyl-6-methoxyphenyl glucitol compound |
AU2011295837B2 (en) | 2010-09-03 | 2015-06-18 | Astrazeneca Uk Limited | Drug formulations using water soluble antioxidants |
WO2012106303A1 (fr) | 2011-02-01 | 2012-08-09 | Bristol-Myers Squibb Company | Formulations pharmaceutiques comprenant un composé amine |
WO2012120052A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation |
WO2012120050A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Nouveaux dérivés phényl-oxathiazine substitués, procédé pour leur préparation, médicaments contenant ces composés et leur utilisation |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
EP2683703B1 (fr) | 2011-03-08 | 2015-05-27 | Sanofi | Nouveaux dérivés phényl-oxathiazine substitués, procédé pour leur préparation, agent pharmaceutique contenant ces composés et leur utilisation |
EP2683704B1 (fr) | 2011-03-08 | 2014-12-17 | Sanofi | Dérivés oxathiazine ramifiés, procédé pour leur préparation, utilisation en tant que médicament, agents pharmaceutiques contenant ces dérivés et leur utilisation |
EP2683699B1 (fr) | 2011-03-08 | 2015-06-24 | Sanofi | Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation |
US8828994B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
WO2012120058A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Dérivés d'oxathiazine substitués par des groupes benzyle ou hétérométhylène, leur procédé de production, leur utilisation comme médicament ainsi que produits pharmaceutiques les contenant et leur utilisation |
WO2012120051A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Dérivés benzyl-oxathiazine substitués avec adamantane ou noradamantane, médicaments contenant ces composés et leur utilisation |
US8614195B2 (en) * | 2011-04-14 | 2013-12-24 | Novartis Ag | Glycoside derivatives and uses thereof |
AR087701A1 (es) * | 2011-08-31 | 2014-04-09 | Japan Tobacco Inc | Derivados de pirazol con actividad inhibidora de sglt1 |
WO2013037390A1 (fr) | 2011-09-12 | 2013-03-21 | Sanofi | Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
EP2760862B1 (fr) | 2011-09-27 | 2015-10-21 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase |
UA113086C2 (xx) | 2012-05-10 | 2016-12-12 | Піразольні сполуки як інгібітори sglt1 | |
TW201425326A (zh) | 2012-10-05 | 2014-07-01 | Lilly Co Eli | 新穎脲化合物 |
AU2014213251B2 (en) | 2013-02-04 | 2017-07-20 | Taisho Pharmaceutical Co., Ltd. | Prophylactic or therapeutic drug for constipation |
EP2774619B1 (fr) | 2013-03-04 | 2016-05-18 | BioActive Food GmbH | Composition pour le traitement de pathologies hyperglycémiques |
AR098670A1 (es) | 2013-11-08 | 2016-06-08 | Lilly Co Eli | Inhibidor de sglt1 |
EP2944311A1 (fr) | 2014-05-16 | 2015-11-18 | BioActive Food GmbH | Combinaison de substances biologiques actives destinée au traitement de pathologies hypoglycémiques |
MX2020010433A (es) * | 2018-04-04 | 2020-10-28 | Japan Tobacco Inc | Compuestos de pirazol sustituidos con heteroarilo y uso farmaceutico de los mismos. |
WO2020113094A1 (fr) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Composés pyrrole et pyrazole et leurs procédés d'utilisation |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU719726B2 (en) * | 1996-12-26 | 2000-05-18 | Tanabe Seiyaku Co., Ltd. | Propiophenone derivatives and process for preparing the same |
TR200201082T2 (tr) * | 1999-08-31 | 2002-07-22 | Kissei Pharmaceutical Co., Ltd. | Glikopriranoziloksipirazol türevleri |
PH12000002657B1 (en) * | 1999-10-12 | 2006-02-21 | Bristol Myers Squibb Co | C-aryl glucoside SGLT2 inhibitors |
WO2002036602A1 (fr) * | 2000-11-02 | 2002-05-10 | Ajinomoto Co., Inc. | Nouveaux derives du pyrazole et remedes au diabete contenant ces derniers |
WO2002064839A2 (fr) * | 2001-02-14 | 2002-08-22 | Tularik Inc. | Gene amplifie de l'hepsine associee au cancer |
RU2356906C2 (ru) * | 2002-08-08 | 2009-05-27 | Киссеи Фармасьютикал Ко., Лтд. | Производные пиразола, лекарственные композиции, содержащие эти производные, их применение в медицине и промежуточные соединения для их получения |
JP2004137245A (ja) * | 2002-08-23 | 2004-05-13 | Kissei Pharmaceut Co Ltd | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
AU2003262262A1 (en) * | 2002-08-27 | 2004-03-19 | Kissei Pharmaceutical Co., Ltd. | Pyrazole derivatives, medicinal composition containing the same, and medicinal use thereof |
AU2003272903A1 (en) * | 2002-10-04 | 2004-04-23 | Kissei Pharmaceutical Co., Ltd. | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same |
AU2003289156A1 (en) * | 2002-12-04 | 2004-06-23 | Kissei Pharmaceutical Co., Ltd. | Preventive or remedy for diseases caused by hyperglycemia |
DE10258008B4 (de) * | 2002-12-12 | 2006-02-02 | Sanofi-Aventis Deutschland Gmbh | Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel |
WO2004113359A1 (fr) * | 2003-06-20 | 2004-12-29 | Kissei Pharmaceutical Co., Ltd. | Derive de pyrazole, composition de medicaments contenant ledit derive et intermediaire de production associe |
-
2004
- 2004-06-11 DE DE102004028241A patent/DE102004028241B4/de not_active Expired - Fee Related
-
2005
- 2005-06-03 AU AU2005252329A patent/AU2005252329B2/en not_active Ceased
- 2005-06-03 RS RSP-2008/0017A patent/RS50541B/sr unknown
- 2005-06-03 EP EP05746637A patent/EP1758914B1/fr active Active
- 2005-06-03 MX MXPA06013513A patent/MXPA06013513A/es active IP Right Grant
- 2005-06-03 SI SI200530142T patent/SI1758914T1/sl unknown
- 2005-06-03 UA UAA200700259A patent/UA89787C2/ru unknown
- 2005-06-03 WO PCT/EP2005/005959 patent/WO2005121161A1/fr active Application Filing
- 2005-06-03 RU RU2007101154/04A patent/RU2370499C2/ru not_active IP Right Cessation
- 2005-06-03 CA CA2570042A patent/CA2570042C/fr not_active Expired - Fee Related
- 2005-06-03 DK DK05746637T patent/DK1758914T3/da active
- 2005-06-03 CN CN200580019067A patent/CN100582116C/zh not_active Expired - Fee Related
- 2005-06-03 DE DE502005002056T patent/DE502005002056D1/de active Active
- 2005-06-03 JP JP2007526254A patent/JP4996464B2/ja not_active Expired - Fee Related
- 2005-06-03 PL PL05746637T patent/PL1758914T3/pl unknown
- 2005-06-03 ES ES05746637T patent/ES2296180T3/es active Active
- 2005-06-03 BR BRPI0510770-9A patent/BRPI0510770A/pt not_active IP Right Cessation
- 2005-06-03 NZ NZ551948A patent/NZ551948A/en not_active IP Right Cessation
- 2005-06-03 PT PT05746637T patent/PT1758914E/pt unknown
- 2005-06-09 TW TW094118973A patent/TWI382030B/zh not_active IP Right Cessation
- 2005-06-09 MY MYPI20052616A patent/MY143565A/en unknown
- 2005-06-10 PE PE2005000666A patent/PE20060297A1/es not_active Application Discontinuation
- 2005-06-10 UY UY28955A patent/UY28955A1/es unknown
- 2005-06-13 AR ARP050102406A patent/AR049393A1/es not_active Application Discontinuation
-
2006
- 2006-10-24 ZA ZA200608832A patent/ZA200608832B/en unknown
- 2006-11-27 CR CR8773A patent/CR8773A/es not_active Application Discontinuation
- 2006-11-30 IL IL179757A patent/IL179757A/en not_active IP Right Cessation
- 2006-12-05 MA MA29515A patent/MA28653B1/fr unknown
- 2006-12-06 US US11/567,410 patent/US7820804B2/en not_active Expired - Fee Related
- 2006-12-08 TN TNP2006000409A patent/TNSN06409A1/en unknown
- 2006-12-08 EC EC2006007054A patent/ECSP067054A/es unknown
-
2007
- 2007-01-10 NO NO20070176A patent/NO20070176L/no not_active Application Discontinuation
- 2007-07-31 HK HK07108324.3A patent/HK1100411A1/xx not_active IP Right Cessation
-
2008
- 2008-01-16 HR HR20080023T patent/HRP20080023T3/xx unknown
- 2008-02-04 CY CY20081100139T patent/CY1107426T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA28653B1 (fr) | Nouveaux derives fluoroglycosidiques des pyrazoles, les medicaments contenant ces composes et leur utilisation | |
MA27559A1 (fr) | Nouveaux derives de fluorglycoside aromatiques, produits pharmaceutiques contenant ces composes et leur utilisation | |
MA27560A1 (fr) | Nouveaux derives de fluorglycoside heterocycliques, produits pharmaceutiques contenant ces composes et leur utilisation | |
MA30609B1 (fr) | Imidazolidine-2,4-diones arylaminoaryl-alkyl-substituees, leur procede de synthese, les medicaments comprenant ces composes, et leurs applications. | |
TNSN01077A1 (fr) | Derives de tropane nouveaux, procede pour leur preparation et compositions les contenant | |
MA27735A1 (fr) | Heterocycles de n-aryle substitues, procede pour leur preparation et leur utilisation en tant que medicaments | |
EA200301306A1 (ru) | Производные 1-фенилсульфонил-1,3-дигидро-2h-индол-2-она, их получение и их терапевтическое применение | |
CN101374807B (zh) | 用于抑制bcl蛋白与结合配偶体的相互作用的化合物和方法 | |
MA27867A1 (fr) | Nouveaux derives de 2h-pyridazine-3-one, compositions pharmaceutiques contenant ces derives et procede de preparation de l'ingredient actif. | |
CA2944211C (fr) | Compositions et methodes pour traiter des maladies neurodegeneratives | |
CN113801073B (zh) | 14-氯-β-榄香烯一氧化氮供体型衍生物及其制备和应用 | |
TNSN00250A1 (fr) | Composes nouveaux inhibiteurs de pcp, procede pour leur preparation et compositions les contenant | |
TNSN02036A1 (fr) | Derives d'acide 3- heterocyclylpropano-hydroxamique nouveaux, et compositions les contenant. | |
KR930000483A (ko) | [(아릴알킬피페리딘-4-일)메틸]-2a,3,4,5-테트라 하이드로-1(2H)-아세나프틸렌-1-온 및 관련 화합물, 이의 제조방법 및 약제로서의 이의 용도 | |
MA27657A1 (fr) | Derives substitues du 3-(benzoylureido) thiophene, leur procede de preparation et leur utilisation | |
MA27963A1 (fr) | Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. | |
MA28026A1 (fr) | Thiénoimidazoles substitués, procédé de production et utilisation de ceux-ci comme médicament ou agent de diagnostic, et médicaments les comprenant | |
MA28325A1 (fr) | Nouveaux derives de phenylpyridinylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
CN101300243A (zh) | 邻位取代苯胺衍生物和抗氧化药 | |
UA90290C2 (ru) | Производные спирокеталов и их применение в качестве лекарственного средства против диабета | |
CA2670468A1 (fr) | Derives de melatonine utilises comme antioxydants | |
FR2859208B1 (fr) | Nouveaux derives de 9-amino-podophyllotoxine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
BRPI0413101A (pt) | compostos de sulfonamida derivado de benzoxazinona, sua preparação e uso como medicamentos | |
WO2006088080A1 (fr) | DÉRIVÉ DE CYCLOHEPTA[b]PYRIDINE-3-CARBONYLGUANIDINE ET PRODUITS PHARMACEUTIQUES CONTENANT LEDIT DÉRIVÉ | |
US20240101584A1 (en) | Targeted delivery of 1,2,4,5 tetraoxane compounds and their uses |