MA27644A1 - Sechage - Google Patents
SechageInfo
- Publication number
- MA27644A1 MA27644A1 MA28276A MA28276A MA27644A1 MA 27644 A1 MA27644 A1 MA 27644A1 MA 28276 A MA28276 A MA 28276A MA 28276 A MA28276 A MA 28276A MA 27644 A1 MA27644 A1 MA 27644A1
- Authority
- MA
- Morocco
- Prior art keywords
- sample
- high viscosity
- solvent
- drying
- samples
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/04—Preserving or maintaining viable microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
- A61K39/13—Poliovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Sampling And Sample Adjustment (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Cette invention a trait à un procédé de séchage de prélèvements biologiques et autres prélèvements instables, permettant de les conserver sous forme de liquides à haute viscosité. Le procédé consiste à préparer un prélèvement à protéger par dissolution et/ou mise en suspension d'un agent actif dans une solution contenant un agent de stabilisation, à soumettre ce prélèvement aux effets d'une température et d'une pression telles que le solvant s'évapore et ce, sans congélation ni formation de bulles, afin d'obtenir une mousse et à extraire le solvant jusqu'à ce que le prélèvement sèche en formant un liquide à haute viscosité.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0225520.6A GB0225520D0 (en) | 2002-11-01 | 2002-11-01 | Drying process |
GB0225532A GB0225532D0 (en) | 2002-11-01 | 2002-11-01 | Drying process |
GB0225543A GB0225543D0 (en) | 2002-11-01 | 2002-11-01 | Immunogenic composition |
GB0317371A GB0317371D0 (en) | 2003-07-24 | 2003-07-24 | Immunogenic composition |
GB0317381A GB0317381D0 (en) | 2003-07-24 | 2003-07-24 | Drying method |
GB0317380A GB0317380D0 (en) | 2003-07-24 | 2003-07-24 | Drying method |
Publications (1)
Publication Number | Publication Date |
---|---|
MA27644A1 true MA27644A1 (fr) | 2005-12-01 |
Family
ID=32234471
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA28276A MA27644A1 (fr) | 2002-11-01 | 2005-05-11 | Sechage |
MA28275A MA27551A1 (fr) | 2002-11-01 | 2005-05-11 | Composition immunogene |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA28275A MA27551A1 (fr) | 2002-11-01 | 2005-05-11 | Composition immunogene |
Country Status (28)
Country | Link |
---|---|
US (3) | US7927858B2 (fr) |
EP (3) | EP1556477B1 (fr) |
JP (2) | JP2006504801A (fr) |
KR (2) | KR101130948B1 (fr) |
AR (2) | AR041881A1 (fr) |
AT (1) | ATE352316T1 (fr) |
AU (2) | AU2003287980B2 (fr) |
BR (1) | BR0315767A (fr) |
CA (2) | CA2503946C (fr) |
CY (2) | CY1119504T1 (fr) |
DE (1) | DE60311526T2 (fr) |
DK (2) | DK1556477T3 (fr) |
ES (3) | ES2280809T3 (fr) |
HK (1) | HK1085380A1 (fr) |
HU (1) | HUE034801T2 (fr) |
IL (2) | IL168054A (fr) |
IS (2) | IS3028B (fr) |
LT (2) | LT1556477T (fr) |
MA (2) | MA27644A1 (fr) |
MX (3) | MXPA05004528A (fr) |
MY (2) | MY132859A (fr) |
NO (3) | NO342741B1 (fr) |
NZ (2) | NZ539706A (fr) |
PL (2) | PL213647B1 (fr) |
PT (2) | PT2395073T (fr) |
SI (2) | SI1556477T1 (fr) |
TW (2) | TW200501981A (fr) |
WO (2) | WO2004039399A1 (fr) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1556477B1 (fr) * | 2002-11-01 | 2017-08-09 | GlaxoSmithKline Biologicals s.a. | Sechage |
US20080176209A1 (en) * | 2004-04-08 | 2008-07-24 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
KR101228356B1 (ko) * | 2004-04-08 | 2013-02-05 | 바이오매트리카 인코포레이티드 | 생명과학용 시료 보관 및 시료 관리의 통합 |
US20060099567A1 (en) * | 2004-04-08 | 2006-05-11 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
GB0409795D0 (en) * | 2004-04-30 | 2004-06-09 | Glaxosmithkline Biolog Sa | Drying method |
TWI398272B (zh) | 2005-03-08 | 2013-06-11 | Intervet Int Bv | 化學定義的安定劑 |
GB0505518D0 (en) * | 2005-03-17 | 2005-04-27 | Chiron Srl | Combination vaccines with whole cell pertussis antigen |
US9789179B2 (en) | 2005-06-27 | 2017-10-17 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
ES2470340T3 (es) * | 2005-12-28 | 2014-06-23 | Advanced Bionutrition Corporation | Vehículo de administración para bacterias probi�ticas que comprende una matriz seca de polisac�ridos, sac�ridos y polioles en forma vítrea |
EA015964B1 (ru) * | 2006-09-07 | 2012-01-30 | Глаксосмитклайн Байолоджикалс С.А. | Вакцина |
JP5285617B2 (ja) | 2006-12-18 | 2013-09-11 | アドバンスド バイオニュートリション コーポレーション | 生きたプロバイオティクスを含む乾燥食物製品 |
CN103933564A (zh) | 2007-05-02 | 2014-07-23 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗 |
ES2393160T3 (es) * | 2007-05-18 | 2012-12-19 | Medimmune, Llc | Conservación de materiales bioactivos con espuma liofilizada |
EP2167686A1 (fr) * | 2007-06-16 | 2010-03-31 | Enigma Diagnostics Ltd. | Compositions |
GB0711683D0 (en) * | 2007-06-16 | 2007-07-25 | Enigma Diagnostics Ltd | Compositions |
CN105147611A (zh) | 2007-07-26 | 2015-12-16 | 圣诺菲·帕斯图尔有限公司 | 抗原佐剂组合物及其方法 |
GB0822633D0 (en) * | 2008-12-11 | 2009-01-21 | Novartis Ag | Formulation |
US9623094B2 (en) | 2009-03-27 | 2017-04-18 | Advanced Bionutrition Corporation | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
MX2011012586A (es) | 2009-05-26 | 2012-03-26 | Advanced Bionutrition Corp | Composicion de polvo seco estable que comprende microorganismos biologicamente activos y/o materiales bioactivos y metodos de elaboracion. |
WO2011032108A2 (fr) * | 2009-09-13 | 2011-03-17 | Vu Truong-Le | Formulation pour la stabilisation à température ambiante d'un vaccin bactérien atténué vivant |
RU2535869C2 (ru) | 2010-01-28 | 2014-12-20 | Эдванст Бионутришн Корпорейшн | Сухая стекловидная композиция для стабилизации и защиты биологически активного материала и способ ее получения |
US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
FR2960781B1 (fr) | 2010-06-07 | 2013-11-22 | Sanofi Pasteur | Preparation d'un vaccin oral sec stabilise, compose d'un virus vivant attenue |
WO2012018639A2 (fr) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions de stabilisation d'adn, d'arn, de protéines salivaires et d'autres échantillons biologiques lors du transport et du stockage à températures ambiantes |
WO2012018638A2 (fr) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions de stabilisation d'adn, d'arn, de protéines dans le sang et d'autres échantillons biologiques lors du transport et du stockage à températures ambiantes |
DK2603100T3 (en) | 2010-08-13 | 2018-08-06 | Advanced Bionutrition Corp | DRY STABILIZING COMPOSITION FOR STORAGE OF BIOLOGICAL MATERIALS |
BR112013005049A2 (pt) | 2010-09-02 | 2016-05-31 | Sanofi Pasteur | estabilizador para a preparação de uma composição vacina da pólio seca injetável |
WO2012075376A2 (fr) | 2010-12-02 | 2012-06-07 | Oncolytics Biotech Inc. | Formulations de virus lyophilisées |
EP2646051A4 (fr) | 2010-12-02 | 2014-05-28 | Oncolytics Biotech Inc | Formulations de virus liquides |
US20120222979A1 (en) | 2011-03-04 | 2012-09-06 | Elwha LLC, a limited liability company of the State of Delaware | Glassy compositions |
SG193963A1 (en) * | 2011-04-07 | 2013-11-29 | Glaxosmithkline Llc | Formulations with reduced viscosity |
CA2832560A1 (fr) * | 2011-04-07 | 2012-10-18 | Glaxosmithkline Llc | Formulations a viscosite reduite |
US20120294894A1 (en) | 2011-05-20 | 2012-11-22 | Nitto Denko Corporation | Pharmaceutical composition and method for producing the same |
US20140302021A1 (en) | 2011-10-25 | 2014-10-09 | Onclave Therapeutics Limited | Antibody formulations and methods |
EP2934572A4 (fr) | 2012-12-20 | 2016-11-23 | Biomatrica Inc | Formulations et procédés pour stabiliser des réactifs pcr |
WO2015050177A1 (fr) * | 2013-10-03 | 2015-04-09 | 日東電工株式会社 | Préparation de vaccin antigrippal séchée, et procédé pour produire une préparation de vaccin antigrippal séchée |
CA2934434C (fr) * | 2013-12-19 | 2022-05-24 | Crucell Holland B.V. | Formulations ameliorees pour des virosomes. |
SG10201807826XA (en) | 2014-02-11 | 2018-10-30 | Massachusetts Inst Technology | Novel full spectrum anti-dengue antibody |
CN113826612B (zh) | 2014-06-10 | 2022-11-22 | 生物马特里卡公司 | 在环境温度下稳定凝血细胞 |
WO2016012385A1 (fr) * | 2014-07-21 | 2016-01-28 | Sanofi Pasteur | Composition de vaccin comprenant du pvi et des cyclodextrines |
AU2016287453A1 (en) | 2015-06-30 | 2017-09-28 | Société des Produits Nestlé S.A. | Composition suitable for protecting microorganisms |
CN108347982A (zh) | 2015-07-29 | 2018-07-31 | 高级生物营养公司 | 用于特殊饮食用途的稳定的干燥益生菌组合物 |
KR20180041237A (ko) * | 2015-09-04 | 2018-04-23 | 인벤트프라이즈 엘엘씨 | Vlp 안정화된 백신 조성물 |
AU2016368265B2 (en) | 2015-12-08 | 2021-10-28 | Biomatrica, Inc. | Reduction of erythrocyte sedimentation rate |
CN109890413B (zh) | 2016-09-02 | 2024-04-16 | 赛诺菲巴斯德股份有限公司 | 脑膜炎奈瑟氏菌疫苗 |
KR20200144120A (ko) * | 2018-04-16 | 2020-12-28 | 메르크 파텐트 게엠베하 | 열 안정성을 개선하기 위한 단백질 제제에 대한 첨가제 |
CN112739207A (zh) * | 2018-09-28 | 2021-04-30 | 株式会社大塚制药工场 | 包含阿卡伯糖或水苏糖的哺乳动物细胞保存用液 |
Family Cites Families (88)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US509893A (en) * | 1893-12-05 | William griesser | ||
DE1157734B (de) | 1961-08-16 | 1963-11-21 | Behringwerke Ag | Verfahren zur Herstellung von haltbaren, oral zu verabreichenden Poliomyelitisvirus-Praeparaten |
US3767790A (en) * | 1972-02-11 | 1973-10-23 | Nat Patent Dev Corp | Microorganisms |
US3929132A (en) * | 1973-04-10 | 1975-12-30 | Alza Corp | Osmotic dispenser |
EP0027888B1 (fr) | 1979-09-21 | 1986-04-16 | Hitachi, Ltd. | Interrupteur à semiconducteur |
US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
GB8323094D0 (en) * | 1983-08-26 | 1983-09-28 | Franks F | Preservation of cells |
US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
IT1187753B (it) | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
DE3682047D1 (de) | 1985-07-09 | 1991-11-21 | Quadrant Bioresources Ltd | Beschuetzung von proteinen und aehnlichem. |
GB8604983D0 (en) * | 1986-02-28 | 1986-04-09 | Biocompatibles Ltd | Protein preservation |
GB8715238D0 (en) | 1987-06-29 | 1987-08-05 | Quadrant Bioresources Ltd | Food process |
GB8801338D0 (en) * | 1988-01-21 | 1988-02-17 | Quadrant Bioresources Ltd | Preservation of viruses |
DE3819530A1 (de) * | 1988-06-08 | 1989-12-21 | Westphal Geb Jauch Christel Dr | Verfahren, traeger und testsatz fuer die kultivierung und mikroskopische untersuchung von zellen |
WO1990006951A1 (fr) | 1988-12-16 | 1990-06-28 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur | Mutants de pneumolysine et vaccins contre le pneumocoque obtenus a partir de tels mutants |
ZA907737B (en) | 1989-09-29 | 1991-07-31 | Nisshin Oil Mills Ltd | Stable immunogen composition for oral administration |
JPH03161441A (ja) | 1989-11-20 | 1991-07-11 | Senjiyu Seiyaku Kk | メイラード反応阻害剤 |
WO1992001460A1 (fr) | 1990-07-16 | 1992-02-06 | The University Of North Carolina | Proteines antigeniques a action limitee par l'incorporation de fer tirees de la bacterie n. meningitidis et associees a la famille de toxines des hemolysines |
US5912336A (en) | 1990-08-23 | 1999-06-15 | University Of North Carolina At Chapel Hill | Isolated nucleic acid molecules encoding transferrin binding proteins from Neisseria gonorrhoeae and Neisseria meningitidis |
DE69133622D1 (de) | 1990-08-23 | 2009-10-01 | Univ North Carolina | Transferrin bindende Proteine aus Neisseria-Gonorrhoeae und Neisseria-Meningitidis. Ihre Verwendung in einem Impfstoff |
US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
US6592876B1 (en) | 1993-04-20 | 2003-07-15 | Uab Research Foundation | Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products |
US5476929A (en) | 1991-02-15 | 1995-12-19 | Uab Research Foundation | Structural gene of pneumococcal protein |
FR2682041B1 (fr) | 1991-10-03 | 1994-01-14 | Pasteur Merieux Serums Vaccins | Vaccin contre les infections a neisseria meningitidis. |
IT1253009B (it) | 1991-12-31 | 1995-07-10 | Sclavo Ricerca S R L | Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini |
EP0911036A3 (fr) | 1992-02-11 | 2001-05-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Structure immunogene à double vecteur |
JP3368902B2 (ja) | 1992-03-02 | 2003-01-20 | カイロン エセ.ピー.アー. | ワクチンおよび診断に有用なHelicobacterpyloriタンパク質 |
IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
PT835663E (pt) | 1992-05-23 | 2010-01-04 | Glaxosmithkline Biolog Sa | Vacinas combinadas compreendendo o antigénio de superfície da hepatite b e outros antigénios |
FR2692592B1 (fr) | 1992-06-19 | 1995-03-31 | Pasteur Merieux Serums Vacc | Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant. |
DE69323264D1 (de) | 1992-10-27 | 1999-03-11 | American Cyanamid Co | Pädiatrische Kombinationsvakzine mit verbesserter Immunogenizität jeder Vakzine komponente |
DK0699076T3 (da) | 1993-05-18 | 2003-03-03 | Univ Ohio State Res Found | Vaccine mod mellemørebetændelse |
AU3191495A (en) | 1994-08-09 | 1996-03-07 | Nisshin Oil Mills, Ltd., The | Peroral immunogen composition and process for producing the same |
US5565204A (en) | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
IL117483A (en) | 1995-03-17 | 2008-03-20 | Bernard Brodeur | MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K. |
US6265567B1 (en) | 1995-04-07 | 2001-07-24 | University Of North Carolina At Chapel Hill | Isolated FrpB nucleic acid molecule |
US5843464A (en) | 1995-06-02 | 1998-12-01 | The Ohio State University | Synthetic chimeric fimbrin peptides |
EP1090642B8 (fr) | 1995-06-07 | 2010-08-11 | GlaxoSmithKline Biologicals s.a. | Vaccins comprenant un conjugué antigènique de polysaccharide-protéine porteuse et une protéine porteuse libre |
SK168497A3 (en) | 1995-06-07 | 1998-07-08 | Biochem Vaccines Inc | Streptococcal heat shock proteins members of the hsp70 family |
IL122482A (en) | 1995-06-07 | 1999-10-28 | Quadrant Holdings Cambridge | Methods for stably incorporating substances within dry foamed glass matrices and compositions obtained thereby |
CN1146444C (zh) | 1995-06-23 | 2004-04-21 | 史密斯克莱·比奇曼生物公司 | 含有吸附于磷酸铝上的多糖偶联抗原的疫苗组合物 |
DE19543770C2 (de) | 1995-11-24 | 1998-11-05 | Metallgesellschaft Ag | Vorrichtung zur Messung von kondensierter Feuchtigkeit in Vorrichtungen und/oder Rohrleitungen der chemischen Technik und deren Verwendung |
WO1997029773A1 (fr) | 1996-02-13 | 1997-08-21 | The Nisshin Oil Mills, Ltd. | Emulsion et poudre renfermant un vaccin et destinees a une administration orale, et procede de production associe |
DE69735715T2 (de) | 1996-05-01 | 2007-03-29 | The Rockefeller University | Cholin-bindendes Protein, welches als gegen Pneumokokken gerichtetes Vakzin verwendet wird |
CA2256333A1 (fr) * | 1996-05-29 | 1997-12-04 | Victor Bronshtein | Accroissement de la duree de conservation par vitrification |
US5766520A (en) * | 1996-07-15 | 1998-06-16 | Universal Preservation Technologies, Inc. | Preservation by foam formation |
PL187935B1 (pl) * | 1996-07-02 | 2004-11-30 | Connaught Lab | Multiwalentna kompozycja immunogenna i jej zastosowanie |
FR2751000B1 (fr) | 1996-07-12 | 1998-10-30 | Inst Nat Sante Rech Med | Adn specifiques des bacteries de l'espece neisseria meningitidis, leurs procedes d'obtention et leurs applications biologiques |
DE19630390A1 (de) | 1996-07-26 | 1998-01-29 | Chiron Behring Gmbh & Co | Proteine, insbesondere Membranproteine von Helicobacter pylori, ihre Herstellung und Verwendung |
US5882871A (en) | 1996-09-24 | 1999-03-16 | Smithkline Beecham Corporation | Saliva binding protein |
US5882896A (en) | 1996-09-24 | 1999-03-16 | Smithkline Beecham Corporation | M protein |
EP0942983B2 (fr) | 1996-10-31 | 2014-09-10 | Human Genome Sciences, Inc. | Antigenes et vaccins actifs contre streptococcus pneumoniae |
US6051238A (en) * | 1996-12-20 | 2000-04-18 | Merck & Co., Inc. | Stabilizers for lyophilized mumps vaccines |
US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
SE511963C2 (sv) | 1997-04-23 | 1999-12-20 | Ericsson Telefon Ab L M | Anordning och förfarande för bestämning av linjespänning i en abonnentlinjekrets |
GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
WO1999003884A2 (fr) | 1997-07-21 | 1999-01-28 | North American Vaccine, Inc. | Compositions de pneumolysine immunogene modifiee utiles en tant que vaccins |
GB9717953D0 (en) | 1997-08-22 | 1997-10-29 | Smithkline Beecham Biolog | Vaccine |
CA2303105A1 (fr) | 1997-09-15 | 1999-03-25 | Pasteur Merieux Msd | Vaccins multivalents |
JP2002536958A (ja) | 1997-11-21 | 2002-11-05 | ジェンセット | Chlamydiapneumoniaeゲノム配列およびポリペプチド、それらのフラグメント、ならびに特に感染症の診断、予防および治療のためのそれらの使用 |
AU5459698A (en) * | 1997-11-26 | 1999-06-15 | Universal Preservation Technologies, Inc. | Preservation of sensitive biological samples by vitrification |
KR100769103B1 (ko) | 1997-11-28 | 2007-10-23 | 세로노 제네틱스 인스티튜트 에스.에이. | 클라미디아 트라코마티스 게놈 서열과 폴리펩티드, 이의단편 및 이의 용도, 특히, 감염의 진단, 예방 및 치료 용도 |
GB9726398D0 (en) | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
SG152917A1 (en) | 1998-01-14 | 2009-06-29 | Chiron Srl | Neisseria meningitidis antigens |
GB9806456D0 (en) | 1998-03-25 | 1998-05-27 | Smithkline Beecham Biolog | Vaccine composition |
NZ507717A (en) | 1998-04-07 | 2004-02-27 | Medimmune Inc | Derivatives of pneumococcal choline binding proteins for vaccines |
GB9807721D0 (en) | 1998-04-08 | 1998-06-10 | Chiron Spa | Antigen |
EP1944371B1 (fr) | 1998-05-01 | 2015-03-04 | Novartis AG | Antigènes de neisseria meningitidis et compositions |
US6306345B1 (en) * | 1998-05-06 | 2001-10-23 | Universal Preservation Technologies, Inc. | Industrial scale barrier technology for preservation of sensitive biological materials at ambient temperatures |
EP1144998A3 (fr) | 1998-10-09 | 2002-08-07 | Chiron Corporation | Sequences genomiques de neisseria et procedes d'utilisation |
CA2347849C (fr) | 1998-10-22 | 2013-06-25 | The University Of Montana | Proteines omp85 de neisseria gonorrhoeae et de neisseria meningitidis, compositions renfermant lesdites proteines et methodes d'utilisation correspondantes |
EP1133572A4 (fr) | 1998-11-12 | 2005-06-15 | Univ California | Sequence genomique de chlamydia pneumoniae |
GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
EP1163000B1 (fr) | 1999-03-19 | 2008-02-27 | GlaxoSmithKline Biologicals S.A. | Vaccin contre des antigenes de bacteries |
US6245568B1 (en) | 1999-03-26 | 2001-06-12 | Merck & Co., Inc. | Human papilloma virus vaccine with disassembled and reassembled virus-like particles |
EP1165796A2 (fr) | 1999-04-09 | 2002-01-02 | Techlab, Inc. | Support proteique recombinant de la toxine a pour vaccins conjugues polysaccharides |
WO2001041800A2 (fr) | 1999-12-02 | 2001-06-14 | Chiron Corporation | Compositions et procedes de stabilisation de molecules biologiques lors dune operation de lyophilisation |
WO2001052885A1 (fr) | 2000-01-17 | 2001-07-26 | Chiron Spa | Vaccin a base de vesicule de membrane externe (omv) comprenant des proteines de membrane externe du serogroupe b de n. meningitis |
CN100339482C (zh) | 2000-02-28 | 2007-09-26 | 启龙股份公司 | 奈瑟球菌蛋白质的杂交表达 |
HU227613B1 (en) * | 2000-06-29 | 2011-09-28 | Glaxosmithkline Biolog Sa | Vaccine composition |
JP2004502415A (ja) | 2000-07-03 | 2004-01-29 | カイロン エセ.ピー.アー. | Chlamydiapneumoniaeに対する免疫化 |
KR100385711B1 (ko) * | 2000-07-05 | 2003-05-27 | 녹십자백신 주식회사 | 디프테리아, 파상풍 톡소이드와 백일해균 및b형간염표면항원을 포함한 4가 혼합백신 및 그 제조방법 |
EP2189473A3 (fr) | 2000-10-27 | 2010-08-11 | Novartis Vaccines and Diagnostics S.r.l. | Acides nucléiques et protéines dérivés des groupes de streptocoques A et B |
RU2323002C2 (ru) | 2001-07-26 | 2008-04-27 | Чирон Срл. | Вакцины, содержащие алюминиевые адъюванты и гистидин |
EP2591771A1 (fr) * | 2002-04-11 | 2013-05-15 | MedImmune, LLC | Conservation de matières bio-actives au moyen de mousse lyophilisée |
EP1556477B1 (fr) * | 2002-11-01 | 2017-08-09 | GlaxoSmithKline Biologicals s.a. | Sechage |
GB0409795D0 (en) | 2004-04-30 | 2004-06-09 | Glaxosmithkline Biolog Sa | Drying method |
US9473463B2 (en) | 2014-07-29 | 2016-10-18 | Combined Conditional Access Development & Support, LLC | Control word and associated entitlement control message caching and reuse |
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