MA26768A1 - Combinaison de chimiotherapie - Google Patents

Combinaison de chimiotherapie

Info

Publication number
MA26768A1
MA26768A1 MA26275A MA26275A MA26768A1 MA 26768 A1 MA26768 A1 MA 26768A1 MA 26275 A MA26275 A MA 26275A MA 26275 A MA26275 A MA 26275A MA 26768 A1 MA26768 A1 MA 26768A1
Authority
MA
Morocco
Prior art keywords
chemotherapy combination
chemotherapy
combination
Prior art date
Application number
MA26275A
Other languages
English (en)
Inventor
Carleton Gowan Richard
Sebolt-Leopold Judith
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of MA26768A1 publication Critical patent/MA26768A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/475Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Seasonings (AREA)
MA26275A 1998-12-22 2001-07-19 Combinaison de chimiotherapie MA26768A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11329198P 1998-12-22 1998-12-22
US16478899P 1999-11-10 1999-11-10

Publications (1)

Publication Number Publication Date
MA26768A1 true MA26768A1 (fr) 2004-12-20

Family

ID=26810891

Family Applications (1)

Application Number Title Priority Date Filing Date
MA26275A MA26768A1 (fr) 1998-12-22 2001-07-19 Combinaison de chimiotherapie

Country Status (31)

Country Link
EP (1) EP1140291B1 (fr)
JP (1) JP2002532570A (fr)
KR (1) KR20010099877A (fr)
CN (1) CN1333698A (fr)
AP (1) AP2001002175A0 (fr)
AT (1) ATE310567T1 (fr)
AU (1) AU2203900A (fr)
BG (1) BG105715A (fr)
BR (1) BR9916839A (fr)
CA (1) CA2352326A1 (fr)
CZ (1) CZ20012139A3 (fr)
DE (1) DE69928568T2 (fr)
EA (1) EA200100687A1 (fr)
EE (1) EE200100339A (fr)
ES (1) ES2253928T3 (fr)
GE (1) GEP20043172B (fr)
HK (1) HK1042057A1 (fr)
HR (1) HRP20010473A2 (fr)
HU (1) HUP0104844A3 (fr)
ID (1) ID30250A (fr)
IL (1) IL143939A0 (fr)
IS (1) IS5969A (fr)
MA (1) MA26768A1 (fr)
NO (1) NO20013099L (fr)
NZ (1) NZ512859A (fr)
OA (1) OA11733A (fr)
PL (1) PL348326A1 (fr)
SK (1) SK8712001A3 (fr)
TR (1) TR200101871T2 (fr)
WO (1) WO2000037141A1 (fr)
YU (1) YU45401A (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE05450B1 (et) 2000-07-19 2011-08-15 Warner-Lambert Company 4-jodofenlaminobenshdroksaamhapete oksgeenitud estrid, nende kristallvormid ja farmatseutilised kompositsioonid ning kasutamine
WO2002017952A2 (fr) 2000-09-01 2002-03-07 Van Andel Institute Inhibition de la voie de la proteine mapkkk: une strategie therapeutique selective contre les melanomes
EP1377312A4 (fr) * 2001-03-22 2004-10-06 Andel Inst Van Facteur letal de l'anthrax inhibant la croissance tumorale et l'angiogenese
NZ518726A (en) 2001-05-09 2004-06-25 Warner Lambert Co Method of treating or inhibiting neutrophil chemotaxis by administering a mek inhibitor
CZ20022216A3 (cs) * 2001-07-02 2003-05-14 Warner-Lambert Company Kombinační chemoterapie
BRPI0415018A (pt) * 2003-10-08 2006-11-28 Teijin Pharma Ltd métodos para a produção de derivados de aminopirrolidina e de antranilamida, e, composto
CA2542210A1 (fr) 2003-10-21 2005-05-06 Warner-Lambert Company Llc Forme polymorphe du n-[(r)-2,3-dihydroxy-propoxy]-3,4-difluoro-2-fluoro-4-iodophenylamino)-benzamide
WO2006045514A1 (fr) * 2004-10-20 2006-05-04 Applied Research Systems Ars Holding N.V. Derives de 3-arylamino pyridine
CN1807413B (zh) * 2005-09-28 2010-05-05 中国医学科学院医药生物技术研究所 咔唑磺酰胺衍生物及其制备方法
ATE504565T1 (de) 2005-10-07 2011-04-15 Exelixis Inc Azetidine als mek-inhibitoren bei der behandlung proliferativer erkrankungen
WO2007054556A1 (fr) 2005-11-11 2007-05-18 Æterna Zentaris Gmbh Nouvelle pyridopyrazine et son utilisation pour la modulation de kinases
EP1790342A1 (fr) 2005-11-11 2007-05-30 Zentaris GmbH Dérivés de pyridopyrazine et leur utilisation comme modulateurs de transduction de signal
US8217042B2 (en) 2005-11-11 2012-07-10 Zentaris Gmbh Pyridopyrazines and their use as modulators of kinases
CN101605540A (zh) 2006-12-14 2009-12-16 埃克塞利希斯股份有限公司 使用mek抑制剂的方法
EP2370568B1 (fr) 2008-12-10 2017-07-19 Dana-Farber Cancer Institute, Inc. Mutations de mek conférant une résistance aux inhibiteurs de mek
CN103002894B (zh) 2010-02-25 2016-04-06 达纳-法伯癌症研究所公司 对braf抑制剂具有抗性的braf突变
EA030276B1 (ru) 2010-03-09 2018-07-31 Дана-Фарбер Кэнсер Инститьют, Инк. Способы идентификации страдающих раком пациентов и лечения рака у пациентов, у которых имеется или развивается резистентность к первой терапии рака
CN103301096B (zh) * 2012-03-14 2015-05-06 中国中化股份有限公司 取代二苯胺类化合物作为制备抗肿瘤药物的应用
WO2013169858A1 (fr) 2012-05-08 2013-11-14 The Broad Institute, Inc. Méthodes de diagnostic et de traitement chez des patients ayant ou présentant un risque de développer une résistance à une thérapie anticancéreuse
IN2015DN03928A (fr) 2012-10-12 2015-10-02 Exelixis Inc
JP6465790B2 (ja) * 2013-02-27 2019-02-06 第一三共株式会社 Mapkシグナル伝達経路を阻害する化合物に対する応答性を予測する方法
CN105384754B (zh) * 2014-09-02 2018-04-20 上海科州药物研发有限公司 作为蛋白激酶抑制剂的杂环类化合物及其制备方法和用途
CN111909053B (zh) * 2020-08-06 2022-12-06 湖北省生物农药工程研究中心 基于二芳胺单元的酰胺类衍生物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL112248A0 (en) * 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
WO1997032604A1 (fr) * 1996-03-07 1997-09-12 Novartis Ag Combinaisons antiproliferatives contenant des oligonucleotides cibles sur raf et des composes chimiotherapeutiques
US6251943B1 (en) * 1997-02-28 2001-06-26 Warner-Lambert Company Method of treating or preventing septic shock by administering a MEK inhibitor
US7183401B1 (en) * 1997-03-21 2007-02-27 Board Of Regents, The University Of Texas System NOEY2 gene compositions and methods of use
US6002008A (en) * 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
US6040321A (en) * 1997-11-12 2000-03-21 Bristol-Myers Squibb Company Aminothiazole inhibitors of cyclin dependent kinases
US5959097A (en) * 1998-11-20 1999-09-28 Isis Pharmaceuticals, Inc. Antisense modulation of MEK2 expression

Also Published As

Publication number Publication date
PL348326A1 (en) 2002-05-20
IS5969A (is) 2001-06-14
DE69928568D1 (de) 2005-12-29
EE200100339A (et) 2002-10-15
DE69928568T2 (de) 2006-07-27
HK1042057A1 (zh) 2002-08-02
CN1333698A (zh) 2002-01-30
JP2002532570A (ja) 2002-10-02
OA11733A (en) 2005-05-12
KR20010099877A (ko) 2001-11-09
SK8712001A3 (en) 2002-02-05
EA200100687A1 (ru) 2001-12-24
CA2352326A1 (fr) 2000-06-29
AU2203900A (en) 2000-07-12
NO20013099D0 (no) 2001-06-21
HRP20010473A2 (en) 2002-08-31
NO20013099L (no) 2001-08-20
EP1140291B1 (fr) 2005-11-23
BG105715A (en) 2002-04-30
ID30250A (id) 2001-11-15
ATE310567T1 (de) 2005-12-15
HUP0104844A3 (en) 2003-05-28
EP1140291A1 (fr) 2001-10-10
WO2000037141A1 (fr) 2000-06-29
GEP20043172B (en) 2004-02-25
HUP0104844A2 (en) 2002-06-29
ES2253928T3 (es) 2006-06-01
CZ20012139A3 (cs) 2002-01-16
YU45401A (sh) 2004-07-15
TR200101871T2 (tr) 2001-10-22
BR9916839A (pt) 2001-10-09
AP2001002175A0 (en) 2001-06-21
WO2000037141A9 (fr) 2000-12-07
NZ512859A (en) 2004-06-25
IL143939A0 (en) 2002-04-21

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