MA26765A1 - Nouveaux esters derives de composes phenyl-cyclohexyl substitues. - Google Patents

Nouveaux esters derives de composes phenyl-cyclohexyl substitues.

Info

Publication number
MA26765A1
MA26765A1 MA26211A MA26211A MA26765A1 MA 26765 A1 MA26765 A1 MA 26765A1 MA 26211 A MA26211 A MA 26211A MA 26211 A MA26211 A MA 26211A MA 26765 A1 MA26765 A1 MA 26765A1
Authority
MA
Morocco
Prior art keywords
substituted phenyl
esters derived
compounds
novel esters
cyclohexyl compounds
Prior art date
Application number
MA26211A
Other languages
English (en)
Inventor
Castillo Nieto Juan Carlos Del
Clotet Joan Huguet
Ramon Amat Elisabet De
Freixa Maria Chalaux
Original Assignee
Vita Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vita Lab filed Critical Vita Lab
Publication of MA26765A1 publication Critical patent/MA26765A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C219/30—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Nouveaux esters dérivés de composés phényl-cyclohexyl substitués, dérivés du Tramadol, procédé pour leur obtention et utilisation de ces composés pour la fabrication d'un médicament ayant des propriétés analgésiques. Ces nouveaux produits de formule générale (I) présentent une activité analgésique supérieure au tramadol, une toxicité inférieure et une durée d'action supérieure.
MA26211A 1998-11-06 2001-05-23 Nouveaux esters derives de composes phenyl-cyclohexyl substitues. MA26765A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009802329A ES2141688B1 (es) 1998-11-06 1998-11-06 Nuevos esteres derivados de compuestos fenil-ciclohexil sustituidos.

Publications (1)

Publication Number Publication Date
MA26765A1 true MA26765A1 (fr) 2004-12-20

Family

ID=8305698

Family Applications (1)

Application Number Title Priority Date Filing Date
MA26211A MA26765A1 (fr) 1998-11-06 2001-05-23 Nouveaux esters derives de composes phenyl-cyclohexyl substitues.

Country Status (39)

Country Link
US (1) US6455585B1 (fr)
EP (3) EP1219594B1 (fr)
JP (1) JP2002529442A (fr)
KR (1) KR100453613B1 (fr)
CN (1) CN1176902C (fr)
AP (1) AP1222A (fr)
AT (3) ATE257817T1 (fr)
AU (1) AU755681B2 (fr)
BG (1) BG105556A (fr)
BR (1) BR9915727A (fr)
CA (1) CA2349245A1 (fr)
CR (1) CR6368A (fr)
CU (1) CU23006A3 (fr)
CZ (1) CZ20011500A3 (fr)
DE (3) DE69914231T2 (fr)
DK (3) DK1219623T3 (fr)
EA (1) EA003742B1 (fr)
EE (1) EE200100246A (fr)
ES (4) ES2141688B1 (fr)
GE (1) GEP20033116B (fr)
HR (1) HRP20010412B1 (fr)
HU (1) HUP0104218A3 (fr)
ID (1) ID29017A (fr)
IL (1) IL142592A0 (fr)
IS (1) IS5934A (fr)
MA (1) MA26765A1 (fr)
MX (1) MXPA01004432A (fr)
NO (1) NO20012234L (fr)
NZ (1) NZ511739A (fr)
OA (1) OA11672A (fr)
PL (1) PL347492A1 (fr)
PT (3) PT1219594E (fr)
SI (3) SI1127871T1 (fr)
SK (1) SK284068B6 (fr)
TR (3) TR200200415T2 (fr)
UA (1) UA59477C2 (fr)
WO (1) WO2000027799A1 (fr)
YU (1) YU29601A (fr)
ZA (1) ZA200104026B (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2160534B1 (es) * 1999-12-30 2002-04-16 Vita Invest Sa Nuevos esteres derivados de (rr,ss)-2-hidroxibenzoato de 3-(2-dimetilaminometil-1-hidroxiciclohexil) fenilo.
DE10049483A1 (de) * 2000-09-29 2002-05-02 Gruenenthal Gmbh Substituierte 1-Aminobutan-3-ol-Derivate
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
AU2003264311A1 (en) * 2002-08-28 2004-04-08 Jin Wang Oral formulations of ibuprofen and tramadol, methods and preparation thereof
ES2640404T3 (es) 2002-11-22 2017-11-02 Grünenthal GmbH Combinación de analgésicos seleccionados con inhibidores de la COX II
US20040248979A1 (en) * 2003-06-03 2004-12-09 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
US8075872B2 (en) 2003-08-06 2011-12-13 Gruenenthal Gmbh Abuse-proofed dosage form
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102004034619A1 (de) * 2004-07-16 2006-02-23 Grünenthal GmbH Substituierte Aminoverbindungen als 5-HT/NA Uptakehemmer
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
NZ586792A (en) 2008-01-25 2012-09-28 Gruenenthal Chemie Tamper resistant controlled release pharmaceutical tablets form having convex and concave surfaces
PT2273983T (pt) 2008-05-09 2016-10-28 Gruenenthal Gmbh Processo para a preparação de uma formulação em pó intermediária e uma forma de dosagem sólida final sob utilização de uma etapa de congelamento por atomização
SI2456424T1 (sl) 2009-07-22 2013-10-30 Gruenenthal Gmbh Oksidacijsko stabilizirana odmerna oblika, varna pred zlorabo
AU2010275753B2 (en) 2009-07-22 2014-08-21 Grünenthal GmbH Hot-melt extruded controlled release dosage form
EP2383255A1 (fr) 2010-04-28 2011-11-02 Lacer, S.A. Nouveaux composés, synthèse et utilisation dans le traitement de la douleur
WO2012028319A1 (fr) 2010-09-02 2012-03-08 Grünenthal GmbH Forme pharmaceutique inviolable comportant un sel inorganique
KR20130137627A (ko) 2010-09-02 2013-12-17 그뤼넨탈 게엠베하 음이온성 중합체를 포함하는 내변조성 투여형
WO2012100423A1 (fr) * 2011-01-27 2012-08-02 Eli Lilly And Company Composés analgésiques, procédés, et formulations
EP2530072A1 (fr) 2011-06-03 2012-12-05 Lacer, S.A. Nouveaux composés, synthèse et utilisation dans le traitement de la douleur
US10702485B2 (en) 2011-07-09 2020-07-07 Syntrix Biosystems Inc. Compositions and methods for overcoming resistance to tramadol
EP2736497B1 (fr) 2011-07-29 2017-08-23 Grünenthal GmbH Comprimé multiparticulaire inviolable fournissant une libération immédiate de médicament
US10201502B2 (en) 2011-07-29 2019-02-12 Gruenenthal Gmbh Tamper-resistant tablet providing immediate drug release
AU2013225106B2 (en) 2012-02-28 2017-11-02 Grunenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
ES2692944T3 (es) 2012-04-18 2018-12-05 Grünenthal GmbH Forma de dosificación farmacéutica resistente a la manipulación y resistente a la descarga rápida de la dosis
WO2013168005A2 (fr) * 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement du syndrome des jambes sans repos et de la fibromyalgie
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
WO2014191397A1 (fr) 2013-05-29 2014-12-04 Grünenthal GmbH Forme pharmaceutique inviolable contenant une ou plusieurs particules
BR112015029616A2 (pt) 2013-05-29 2017-07-25 Gruenenthal Gmbh forma de dosagem resistente à adulteração com perfil de liberação bimodal
MX368846B (es) 2013-07-12 2019-10-18 Gruenenthal Gmbh Forma de dosificación resistente a la alteración que contiene polímero de acetato de etilen-vinilo.
CA2931553C (fr) 2013-11-26 2022-01-18 Grunenthal Gmbh Preparation de composition pharmaceutique en poudre par cryo-broyage
CA2947786A1 (fr) 2014-05-12 2015-11-19 Grunenthal Gmbh Formulation pour capsule a liberation immediate resistant aux manipulations illicites comprenant du tapentadol
EP3285745A1 (fr) 2015-04-24 2018-02-28 Grünenthal GmbH Forme galénique inviolable avec libération immédiate et résistance à l'extraction par solvant.
CA2998259A1 (fr) 2015-09-10 2017-03-16 Grunenthal Gmbh Protection contre un surdosage par voie orale a l'aide de formulations a liberation immediate dissuasives d'abus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1199764B (de) * 1963-04-02 1965-09-02 Gruenenthal Chemie Verfahren zur Herstellung von basisch substituierten Phenolaethern
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe

Also Published As

Publication number Publication date
UA59477C2 (uk) 2003-09-15
CA2349245A1 (fr) 2000-05-18
ATE249418T1 (de) 2003-09-15
DE69914231T2 (de) 2004-11-11
DK1219594T3 (da) 2004-04-19
SI1219594T1 (en) 2004-06-30
ES2213731T3 (es) 2004-09-01
CN1176902C (zh) 2004-11-24
PT1219623E (pt) 2004-04-30
ID29017A (id) 2001-07-26
DE69914229D1 (de) 2004-02-19
NZ511739A (en) 2002-11-26
ES2141688B1 (es) 2001-02-01
SK5842001A3 (en) 2001-12-03
TR200200416T2 (tr) 2003-01-21
HRP20010412B1 (en) 2004-04-30
YU29601A (sh) 2003-04-30
HRP20010412A2 (en) 2002-12-31
BR9915727A (pt) 2001-09-04
AU755681B2 (en) 2002-12-19
EP1127871A1 (fr) 2001-08-29
CZ20011500A3 (cs) 2001-09-12
NO20012234D0 (no) 2001-05-04
TR200200415T2 (tr) 2002-06-21
PT1219594E (pt) 2004-04-30
US6455585B1 (en) 2002-09-24
WO2000027799A1 (fr) 2000-05-18
EP1219623B1 (fr) 2004-01-14
DE69914229T2 (de) 2004-12-09
ES2207298T3 (es) 2004-05-16
GEP20033116B (en) 2003-11-25
ES2213732T3 (es) 2004-09-01
EA200100476A1 (ru) 2002-02-28
DK1219623T3 (da) 2004-04-19
EE200100246A (et) 2002-12-16
DE69914231D1 (de) 2004-02-19
EP1219594B1 (fr) 2004-01-14
HUP0104218A3 (en) 2002-11-28
DE69911235T2 (de) 2004-07-01
DK1127871T3 (da) 2003-11-24
PT1127871E (pt) 2003-12-31
OA11672A (en) 2005-01-12
AP1222A (en) 2003-11-06
ES2141688A1 (es) 2000-05-16
CN1325377A (zh) 2001-12-05
KR100453613B1 (ko) 2004-10-20
AU1047300A (en) 2000-05-29
EP1127871B1 (fr) 2003-09-10
BG105556A (en) 2001-12-29
ATE257837T1 (de) 2004-01-15
DE69911235D1 (de) 2003-10-16
SK284068B6 (sk) 2004-09-08
SI1219623T1 (en) 2004-06-30
HUP0104218A2 (hu) 2002-03-28
ZA200104026B (en) 2002-05-17
EP1219623A1 (fr) 2002-07-03
IS5934A (is) 2001-05-03
SI1127871T1 (en) 2004-02-29
MXPA01004432A (es) 2002-09-18
IL142592A0 (en) 2002-03-10
TR200101160T2 (tr) 2002-01-21
ATE257817T1 (de) 2004-01-15
PL347492A1 (en) 2002-04-08
EA003742B1 (ru) 2003-08-28
KR20010080942A (ko) 2001-08-25
NO20012234L (no) 2001-05-04
EP1219594A1 (fr) 2002-07-03
CR6368A (es) 2002-04-08
JP2002529442A (ja) 2002-09-10
CU23006A3 (es) 2004-12-17

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