LU603125B1 - A wireless wearable self-adhesive sensor using saliva for power generation and its preparation method - Google Patents
A wireless wearable self-adhesive sensor using saliva for power generation and its preparation methodInfo
- Publication number
- LU603125B1 LU603125B1 LU603125A LU603125A LU603125B1 LU 603125 B1 LU603125 B1 LU 603125B1 LU 603125 A LU603125 A LU 603125A LU 603125 A LU603125 A LU 603125A LU 603125 B1 LU603125 B1 LU 603125B1
- Authority
- LU
- Luxembourg
- Prior art keywords
- preparation
- saliva
- solution
- silk fibroin
- wireless wearable
- Prior art date
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Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
- H01M4/00—Electrodes
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01G—CAPACITORS; CAPACITORS, RECTIFIERS, DETECTORS, SWITCHING DEVICES, LIGHT-SENSITIVE OR TEMPERATURE-SENSITIVE DEVICES OF THE ELECTROLYTIC TYPE
- H01G11/00—Hybrid capacitors, i.e. capacitors having different positive and negative electrodes; Electric double-layer [EDL] capacitors; Processes for the manufacture thereof or of parts thereof
- H01G11/84—Processes for the manufacture of hybrid or EDL capacitors, or components thereof
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The present invention relates to the field of flexible wearable energy devices, in particular to a wireless wearable self-adhesive sensor powered by saliva and its preparation method. The preparation method comprises the following steps: preparing MXene nanosheets and silk fibroin powder; adding MXene nanosheets, pyrrole, and silk fibroin powder into a polyethylene solution and mixing uniformly, then adding a borax mixture and glycerol for reaction to obtain a conductive hydrogel; coating the conductive hydrogel on both sides of a separator, sealing with the separator, and introducing saliva to obtain the wireless wearable self-adhesive sensor powered by saliva. The present invention prepares a wireless wearable self- adhesive sensor powered by saliva using conductive hydrogel Ti₃C₂/PPy/SF/PVA and a separator. The sensor possesses self-adhesiveness, eliminating the need for additional wearing devices such as mouthguards, providing high comfort and minimal foreign body sensation.
Description
DESCRIPTION 0003165
A WIRELESS WEARABLE SELF-ADHESIVE SENSOR USING SALIVA
FOR POWER GENERATION AND ITS PREPARATION METHOD
The present invention relates to the field of flexible wearable energy devices, in particular to a wireless wearable self-adhesive sensor using saliva for power generation and its preparation method.
Flexible wearable energy devices are widely applied in human physiological monitoring, including pulse monitoring, evaluation of body fluids such as sweat and saliva, and identification of toxic substances in the living environment. In order to achieve rapid charging, simplify the manufacturing process, and enhance cycle stability, scientists have invented various flexible supercapacitors, enriching the range of choices for wearable electronic products. When designing safe and effective wearable flexible supercapacitors, it is first necessary to overcome the biocompatibility problems of electrodes and electrolytes. Saliva plays an important role in maintaining oral health and overall health, and its main components include water, enzymes, electrolytes, proteins, urea, etc. The proportion of each component is closely related to oral health and overall health. Therefore, real-time monitoring of the various components in saliva can quickly and effectively evaluate the health status of the human body and carry out risk prediction of related diseases.
Chinese invention patent CN202310835743.X discloses that a saliva sensor is integrated into a mouthguard, which is worn on the teeth of fasting patients in an intensive care unit.
The sensor array monitors in real time the concentration of biomarkers and the 0603125 oral temperature in the saliva of fasting patients. A mobile application terminal, based on the real-time monitored concentration of biomarkers and oral temperature in the saliva of fasting patients, determines the concentration of biomarkers in the blood of fasting patients, and then, according to the concentration of biomarkers in the blood, carries out critical illness warning. In this way, real-time detection and early warning of biomarkers in fasting patients in the intensive care unit are achieved in a non-invasive manner, avoiding the delayed judgment of condition changes caused by intermittent biochemical blood tests. However, the defect in the above technical solution is that it requires wearing an additional mouthguard, which may affect functions such as chewing and breathing, with a strong foreign body sensation, and it does not mention the charging method of the sensor.
Therefore, it is necessary to provide a small-volume, non-toxic, harmless, highly biocompatible, wearable, self-adhesive wireless biosensor for saliva monitoring. A wearable flexible supercapacitor for oral use that employs saliva as the electrolyte is the best method to solve this problem.
SUMMARY LU603125
Based on the above content, the present invention provides a wireless wearable self-adhesive sensor powered by saliva and its preparation method.
To achieve the above purpose, the present invention provides the following scheme:
The present invention provides a preparation method of a wireless wearable self-adhesive sensor powered by saliva, comprising the following steps:
Dispersing TisC> nanosheets in water for ultrasonic treatment, then centrifuging and drying to obtain MXene nanosheets;
Dispersing cocoons in Na2COs solution and boiling, washing and then drying to obtain substance A; dissolving said substance A in a mixed solution, dialyzing to obtain silk fibroin (SF) concentrated solution; vacuum drying the silk fibroin concentrated solution to obtain silk fibroin powder;
Adding MXene nanosheets, pyrrole, and silk fibroin powder into a polyvinyl solution and mixing uniformly, then adding borax mixed solution and glycerol for reaction to obtain conductive hydrogel (TisC2/PPy/SF/P VA);
Coating said conductive hydrogel on both sides of a separator, sealing with the separator and introducing saliva to obtain said wireless wearable self-adhesive sensor powered by saliva.
In some embodiments of the present invention, TisC2 nanosheets are prepared by LiF/HCI etching method, being multilayer TisC2 nanosheets; multilayer TisC» nanosheets obtained by other approaches such as commercial sources are also applicable to the present invention.
In the preferred embodiment of the present invention, the mass fraction of the
Na>COs solution is 0.5%.
In the preferred embodiment of the present invention, the boiling time is 30 min.
In the preferred embodiment of the present invention, the mixed solution is a mixture of CaCl,, CH3CH20H, and H20 with a mass ratio of 1:2:8.
In the preferred embodiment of the present invention, the polyvinyl solution is 0603125 prepared by adding polyvinyl powder into water and stirring vigorously at 95 °C for 2 hours; the mass concentration of the polyvinyl solution is 10%—15%.
In the preferred embodiment of the present invention, the volume-mass ratio of the polyvinyl solution to the MXene nanosheets, pyrrole, and silk fibroin powder is mL:0.3 g:0.15 g:0.8 g.
In the preferred embodiment of the present invention, the borax mixed solution is a mixture of borax and water; the mass concentration of the borax mixed solution is 4%.
In the preferred embodiment of the present invention, the volume ratio of the polyvinyl solution to the borax mixed solution and glycerol is 15:5:1.
Technical scheme two of the present invention: a wireless wearable self- adhesive sensor powered by saliva prepared according to the above preparation method.
The present invention discloses the following technical effects:
The present invention uses conductive hydrogel TisCz/PPy/SF/PVA and separator to prepare a wireless wearable self-adhesive sensor powered by saliva, which has self-adhesion, requires no additional wearing devices such as mouthguards, has high comfort and low foreign body sensation. In addition, the sensor is powered by saliva, providing charging for biosensors, detection devices, etc., and can achieve the purpose of wireless wearable use.
Various exemplary embodiments of the present invention will now be described in detail. This detailed description should not be construed as limiting the present invention, but rather as providing a more detailed description of certain aspects, features, and embodiments of the present invention.
It should be understood that the terminology used herein is intended only to describe particular embodiments and is not intended to limit the present invention.
Furthermore, for numerical ranges herein, it should be understood that each 0605125 intervening value between the upper and lower limits of that range is specifically disclosed. Each smaller range between any stated value or stated range, and any intervening value between any other stated value or intervening value in that stated range, is also encompassed within the present invention. The upper and lower limits of these smaller ranges may independently be included or excluded within the range.
Unless otherwise indicated, all technical and scientific terms used herein have the same meanings as commonly understood by one of ordinary skill in the art to which this invention pertains. Although preferred methods and materials are described herein, any methods and materials similar or equivalent to those described herein can also be used in the practice or testing of the present invention.
All references cited in this specification are incorporated by reference to disclose and describe the methods and/or materials to which they relate. In the event of a conflict with any incorporated reference, the present specification controls. Various modifications and variations may be made to the specific embodiments described in this specification without departing from the scope or spirit of the present invention, as will be apparent to those skilled in the art. Other embodiments resulting from this description will be apparent to those skilled in the art. The present specification and examples are intended to be illustrative only.
The terms "comprising," "including," "having," "containing," and the like as used herein are open-ended, meaning to include but not be limited to.
The technical solutions described in this invention, unless otherwise specified, are conventional in the art. All reagents and raw materials used, unless otherwise specified, are commercially available or publicly available.
The technical solutions provided by this invention are described in detail below with reference to the examples, but these should not be construed as limiting the scope of protection of this invention.
Example 1 LU603125
The present embodiment provides a preparation method of a wireless wearable self-adhesive sensor (TisC:/PPy/SF/PVA) powered by saliva, comprising the following steps: a. Disperse TisC2 nanosheets in deionized water, perform ultrasonic treatment under argon protection for 40 minutes, centrifuge the supernatant at 3500 rpm for minutes, and finally vacuum-filter to obtain MXene nanosheets, followed by vacuum drying at 70 °C. b. Disperse silkworm cocoons in 0.5% (w/w) Na2COs solution, boil for 30 minutes for degumming, wash with deionized water, and dry in an oven at 60 °C.
Dissolve the dried material in a CaCl», CH3CH20H, and H2O solution (mass ratio 1:2:8) at 75 °C, and place the obtained solution into a cellulose dialysis membrane (MWCO 8000-14000 Da) for dialysis in deionized water for 3 days to obtain a silk fibroin (SF) concentrated solution. Vacuum dry the concentrated solution to obtain silk fibroin powder. c. Mix 2.0 g of polyvinyl alcohol (PVA) powder with 15 mL of deionized water, and stir vigorously at 95 °C for 2 hours to form a polyvinyl alcohol solution. d. Add 0.3 g of two-dimensional nanomaterial Ti;C, and 0.15 g of pyrrole (PPy) into the above polyvinyl alcohol solution, stir for 1 hour, then add 0.8 g of silk fibroin powder and stir vigorously for another 1 hour. Subsequently, add 5 mL of aqueous solution containing 0.2 g of borax and 1 mL of glycerol, and stir for 30 minutes to obtain a conductive hydrogel. e. Coat the above conductive hydrogel on both sides of a cellulose separator.
Based on two similar active regions of TisCa/PPy/SF/PVA electrodes, a symmetric
TisC/PPy/SF/PVA electrochemical capacitor was prepared. The electrochemical capacitor was sealed with a separator composed of polyvinylidene fluoride (PVDF) and polyvinyl fluoride (PVF), and saliva was introduced as the electrolyte, successfully constructing a wireless wearable self-adhesive sensor (TisCz /PPy/SF/PVA) powered by saliva.
On the basis of Example 1, by adjusting the mass ratios of polyvinyl alcohol, 0603125 silk fibroin, MXene, and pyrrole, a series of conductive hydrogels with different physicochemical properties can be obtained, thereby regulating the performance of the wireless wearable self-adhesive sensor powered by saliva.
In this embodiment, the sensor prepared using conductive hydrogel TisC2 /PPy/SF/PVA and separator exhibits self-adhesion, can be powered by saliva, and provides charging for biosensors, detection devices, and other applications, thereby achieving the purpose of wireless wearable use.
The invention employs MXene hydrogel as the capacitor medium, designing a layered wearable capacitor structure of medium—separator—saliva-medium, which enables electricity generation from saliva. The self-adhesive sensor can be directly attached to the tooth or mucosal surface without the aid of additional fixation devices. By presetting the assembly position of the sensor, a wireless wearable self- adhesive sensor powered by saliva is realized.
The above embodiment only illustrates a preferred implementation of the invention and does not limit the scope of the invention. Various modifications and improvements made by those skilled in the art without departing from the spirit of the invention shall fall within the scope of protection defined by the claims of the present invention.
Claims (9)
1. A preparation method of a wireless wearable self-adhesive sensor using saliva for power generation, characterized in that it comprises the following steps: dispersing TisC2 nanosheets in water for ultrasonic treatment, then centrifuging and drying to obtain MXene nanosheets; dispersing silkworm cocoons in Na:CO3 solution and boiling, washing and then drying to obtain substance A; dissolving the substance A in a mixed solution, dialyzing to obtain a silk fibroin concentrated solution; vacuum drying the silk fibroin concentrated solution to obtain silk fibroin powder; adding MXene nanosheets, pyrrole, and silk fibroin powder into a polyethylene solution and mixing evenly, then adding a borax mixed solution and glycerol to react to obtain a conductive hydrogel; coating the conductive hydrogel on both sides of a diaphragm, using the diaphragm for sealing and introducing saliva to obtain the wireless wearable self-adhesive sensor using saliva for power generation.
2. The preparation method according to claim 1, characterized in that the mass fraction of the Na2COs solution is 0.5%.
3. The preparation method according to claim 1, characterized in that the boiling time is 30 min.
4. The preparation method according to claim 1, characterized in that the mixed solution is a mixture of CaClz, CHsCH20H, and H20 with a mass ratio of 1:2:8.
5. The preparation method according to claim 1, characterized in that the polyethylene solution is prepared by adding polyethylene powder into water and stirring vigorously at 95°C for 2 hours; the mass concentration of the polyethylene solution is 10%~15%.
6. The preparation method according to claim 1, characterized in that the 0603125 volume-mass ratio of the polyethylene solution to the MXene nanosheets, pyrrole, and silk fibroin powder is 15 ML:0.3 g:0.15 g:0.8 g.
7. The preparation method according to claim 1, characterized in that the borax mixed solution is a mixture of borax and water; the mass concentration of the borax mixed solution is 4%.
8. The preparation method according to claim 1, characterized in that the volume ratio of the polyethylene solution to the borax mixed solution and glycerol is 15:5:1.
9. À wireless wearable self-adhesive sensor using saliva for power generation prepared by the preparation method according to claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU603125A LU603125B1 (en) | 2025-09-04 | 2025-09-04 | A wireless wearable self-adhesive sensor using saliva for power generation and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU603125A LU603125B1 (en) | 2025-09-04 | 2025-09-04 | A wireless wearable self-adhesive sensor using saliva for power generation and its preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LU603125B1 true LU603125B1 (en) | 2026-03-04 |
Family
ID=98974741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LU603125A LU603125B1 (en) | 2025-09-04 | 2025-09-04 | A wireless wearable self-adhesive sensor using saliva for power generation and its preparation method |
Country Status (1)
| Country | Link |
|---|---|
| LU (1) | LU603125B1 (en) |
-
2025
- 2025-09-04 LU LU603125A patent/LU603125B1/en active
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