LT3398B - Process for preparing deacylated 10-baccatine iii - Google Patents

Process for preparing deacylated 10-baccatine iii Download PDF

Info

Publication number
LT3398B
LT3398B LTIP1397A LTIP1397A LT3398B LT 3398 B LT3398 B LT 3398B LT IP1397 A LTIP1397 A LT IP1397A LT IP1397 A LTIP1397 A LT IP1397A LT 3398 B LT3398 B LT 3398B
Authority
LT
Lithuania
Prior art keywords
process according
deacetyl
ether
baccatin iii
butyl
Prior art date
Application number
LTIP1397A
Other languages
English (en)
Lithuanian (lt)
Inventor
Jean-Claude Gaullier
Bernadette Mandard
Rodolphe Margraff
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of LTIP1397A publication Critical patent/LTIP1397A/xx
Publication of LT3398B publication Critical patent/LT3398B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Compounds Of Unknown Constitution (AREA)
LTIP1397A 1992-10-05 1993-10-04 Process for preparing deacylated 10-baccatine iii LT3398B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9211746A FR2696463B1 (fr) 1992-10-05 1992-10-05 Procédé d'obtention de la désacétyl-10 baccatine III.

Publications (2)

Publication Number Publication Date
LTIP1397A LTIP1397A (en) 1994-11-25
LT3398B true LT3398B (en) 1995-09-25

Family

ID=9434124

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1397A LT3398B (en) 1992-10-05 1993-10-04 Process for preparing deacylated 10-baccatine iii

Country Status (30)

Country Link
US (1) US5393895A (uk)
EP (1) EP0663910B1 (uk)
JP (1) JP3299754B2 (uk)
KR (1) KR100301236B1 (uk)
CN (1) CN1043530C (uk)
AT (1) ATE148883T1 (uk)
AU (1) AU680629B2 (uk)
CA (1) CA2146373C (uk)
CZ (2) CZ284615B6 (uk)
DE (1) DE69308155T2 (uk)
DK (1) DK0663910T3 (uk)
EE (1) EE03126B1 (uk)
ES (1) ES2098061T3 (uk)
FI (1) FI109794B (uk)
FR (1) FR2696463B1 (uk)
GE (1) GEP20001937B (uk)
GR (1) GR3022617T3 (uk)
HU (1) HU226862B1 (uk)
LT (1) LT3398B (uk)
LV (1) LV10621B (uk)
MX (1) MX9305771A (uk)
NO (1) NO310413B1 (uk)
NZ (1) NZ256450A (uk)
PL (1) PL177316B1 (uk)
RU (1) RU2107065C1 (uk)
SK (1) SK280949B6 (uk)
TW (1) TW255890B (uk)
UA (1) UA44227C2 (uk)
WO (1) WO1994007882A1 (uk)
ZA (1) ZA937313B (uk)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2696462B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
CA2468375A1 (en) 1993-07-19 1995-02-02 Angiotech Pharmaceuticals, Inc. Anti-angiogenic compositions, uses and methods
ES2144533T3 (es) * 1993-11-02 2000-06-16 Rhone Poulenc Rorer Gmbh Procedimiento para la separacion de una mezcla.
FR2714053B1 (fr) * 1993-12-22 1996-03-08 Pf Medicament Procédé d'extraction et d'isolement de la 10-désacétylbaccatine III.
CN1112433A (zh) * 1994-05-24 1995-11-29 郭明 红豆杉属植物提取物及其应用
AU716005B2 (en) 1995-06-07 2000-02-17 Cook Medical Technologies Llc Implantable medical device
FR2736355B1 (fr) * 1995-07-07 1997-11-07 Pf Medicament Procede d'extraction et d'isolement de la 10-desacetylbaccatine iii
US5750736A (en) * 1996-07-11 1998-05-12 Napro Biotherapeutics, Inc. Method for acylating 10-deacetylbaccatin III selectively at the c-10 position
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US6111144A (en) * 1997-08-21 2000-08-29 Florida State University Method for the synthesis of a taxane intermediate
US6002024A (en) * 1998-07-27 1999-12-14 Dabur Research Foundation Process for the isolation of 14β-hydroxy-10-deacetyl baccatin-III
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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814470A (en) 1986-07-17 1989-03-21 Rhone-Poulenc Sante Taxol derivatives, their preparation and pharmaceutical compositions containing them
US4924011A (en) 1988-04-06 1990-05-08 Centre National De La Recherche Scientifique Process for preparing taxol
US4924012A (en) 1988-04-06 1990-05-08 Rhone-Poulenc Sante Process for preparing derivatives of baccatine III and of 10-deacetyl baccatine III
EP0400971A2 (en) 1989-05-31 1990-12-05 Florida State University Method for preparation of taxol
EP0428376A1 (en) 1989-11-14 1991-05-22 Florida State University Method for preparation of taxol using an oxazinone
WO1992009589A1 (fr) 1990-11-23 1992-06-11 Rhone-Poulenc Rorer S.A. Procede de preparation de derives du taxane, nouveaux derives obtenus et compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

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Publication number Priority date Publication date Assignee Title
US5380916A (en) 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives
EP0580759B1 (en) * 1991-04-19 1999-05-26 The University Of Mississippi Methods and compositions for isolating taxanes
IT1258838B (it) 1992-01-31 1996-02-29 Indena Spa Processo per l'estrazione di tassolo e derivati da cultivar del genere taxus

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814470A (en) 1986-07-17 1989-03-21 Rhone-Poulenc Sante Taxol derivatives, their preparation and pharmaceutical compositions containing them
US4924011A (en) 1988-04-06 1990-05-08 Centre National De La Recherche Scientifique Process for preparing taxol
US4924012A (en) 1988-04-06 1990-05-08 Rhone-Poulenc Sante Process for preparing derivatives of baccatine III and of 10-deacetyl baccatine III
EP0400971A2 (en) 1989-05-31 1990-12-05 Florida State University Method for preparation of taxol
EP0428376A1 (en) 1989-11-14 1991-05-22 Florida State University Method for preparation of taxol using an oxazinone
WO1992009589A1 (fr) 1990-11-23 1992-06-11 Rhone-Poulenc Rorer S.A. Procede de preparation de derives du taxane, nouveaux derives obtenus et compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
FR2696463B1 (fr) 1994-11-25
CA2146373A1 (fr) 1994-04-14
FI951596A (fi) 1995-04-04
CZ287065B6 (cs) 2000-08-16
MX9305771A (es) 1994-05-31
PL308244A1 (en) 1995-07-24
FI951596A0 (fi) 1995-04-04
FI109794B (fi) 2002-10-15
PL177316B1 (pl) 1999-10-29
DE69308155D1 (de) 1997-03-27
CZ284615B6 (cs) 1999-01-13
ES2098061T3 (es) 1997-04-16
US5393895A (en) 1995-02-28
AU680629B2 (en) 1997-08-07
DE69308155T2 (de) 1997-08-07
CZ84595A3 (en) 1995-09-13
WO1994007882A1 (fr) 1994-04-14
LTIP1397A (en) 1994-11-25
GR3022617T3 (en) 1997-05-31
RU95110687A (ru) 1996-12-27
ATE148883T1 (de) 1997-02-15
UA44227C2 (uk) 2002-02-15
NO310413B1 (no) 2001-07-02
GEP20001937B (en) 2000-02-05
HU226862B1 (en) 2009-12-28
LV10621B (en) 1995-10-20
TW255890B (uk) 1995-09-01
EP0663910B1 (fr) 1997-02-12
KR100301236B1 (ko) 2001-11-22
NZ256450A (en) 1996-11-26
LV10621A (lv) 1995-04-20
JP3299754B2 (ja) 2002-07-08
HU9500973D0 (en) 1995-06-28
EP0663910A1 (fr) 1995-07-26
AU5115593A (en) 1994-04-26
EE03126B1 (et) 1998-10-15
ZA937313B (en) 1994-04-25
JPH08501792A (ja) 1996-02-27
CN1043530C (zh) 1999-06-02
SK43395A3 (en) 1995-08-09
NO951282L (no) 1995-04-03
CA2146373C (fr) 2006-08-29
NO951282D0 (no) 1995-04-03
HUT72449A (en) 1996-04-29
FR2696463A1 (fr) 1994-04-08
CN1085551A (zh) 1994-04-20
KR950703550A (ko) 1995-09-20
DK0663910T3 (da) 1997-03-10
SK280949B6 (sk) 2000-09-12
RU2107065C1 (ru) 1998-03-20

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Effective date: 20131004