LT3130B - The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs - Google Patents

The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs Download PDF

Info

Publication number
LT3130B
LT3130B LTIP112A LTIP112A LT3130B LT 3130 B LT3130 B LT 3130B LT IP112 A LTIP112 A LT IP112A LT IP112 A LTIP112 A LT IP112A LT 3130 B LT3130 B LT 3130B
Authority
LT
Lithuania
Prior art keywords
preparation according
layer
drug
medetomidine
salt
Prior art date
Application number
LTIP112A
Other languages
English (en)
Lithuanian (lt)
Inventor
Harry Jalonen
Arto Johannes Karjalainen
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of LTIP112A publication Critical patent/LTIP112A/xx
Publication of LT3130B publication Critical patent/LT3130B/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LTIP112A 1991-05-31 1992-05-29 The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs LT3130B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919111732A GB9111732D0 (en) 1991-05-31 1991-05-31 The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs

Publications (2)

Publication Number Publication Date
LTIP112A LTIP112A (en) 1994-07-15
LT3130B true LT3130B (en) 1994-12-25

Family

ID=10695876

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP112A LT3130B (en) 1991-05-31 1992-05-29 The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs

Country Status (17)

Country Link
US (1) US5438067A (fi)
EP (1) EP0587819B1 (fi)
JP (2) JP3483881B2 (fi)
AT (1) ATE149090T1 (fi)
AU (1) AU1798192A (fi)
CA (1) CA2110161C (fi)
DE (1) DE69217658T2 (fi)
EE (1) EE03053B1 (fi)
FI (1) FI104948B (fi)
GB (2) GB9111732D0 (fi)
IE (1) IE67168B1 (fi)
LT (1) LT3130B (fi)
LV (1) LV10047B (fi)
NO (1) NO303818B1 (fi)
NZ (1) NZ242717A (fi)
WO (1) WO1992021338A1 (fi)
ZA (1) ZA923395B (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883115A (en) * 1992-11-09 1999-03-16 Pharmetrix Division Technical Chemicals & Products, Inc. Transdermal delivery of the eutomer of a chiral drug
GB2290964A (en) * 1994-07-08 1996-01-17 Arto Olavi Urtti Transdermal drug delivery system
GB9521680D0 (en) * 1995-10-23 1996-01-03 Orion Yhtymo Oy New use of imidazole derivatives
US5730721A (en) 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
IT1290255B1 (it) * 1997-02-05 1998-10-22 Wallcovering Pubblicita S R L Supporto sagomato aderente all'epidermide per la cessione di sostanze cosmetiche o farmacologiche e metodo per la sua fabbricazione
DE19936395C2 (de) 1999-08-03 2002-07-18 Antonia Buntz Kosmetikpflaster und Verfahren zum Anheben der weiblichen Brust mittels eines solchen Kosmetikpflasters und seine Verwendung
US6682757B1 (en) * 2000-11-16 2004-01-27 Euro-Celtique, S.A. Titratable dosage transdermal delivery system
US7795263B2 (en) * 2008-07-08 2010-09-14 Wildlife Laboratories, Inc. Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
CN102639131A (zh) * 2009-05-15 2012-08-15 瑞克欧制药有限公司 舌下右美托咪定组合物及其使用方法
WO2011085162A2 (en) * 2010-01-08 2011-07-14 Recro Pharma, Inc. Topical transdermal dexmedetomidine compositions and methods of use thereof
US20120202863A1 (en) * 2011-02-03 2012-08-09 Gerald Horn Compositions and methods for treatment of glaucoma
EP2787970B1 (en) 2011-12-11 2018-04-11 Recro Pharma, Inc. Intranasal dexmedetomidine compositions and methods of use thereof
US20150098997A1 (en) * 2013-10-07 2015-04-09 Teikoku Pharma Usa, Inc. Methods and Compositions for Treating Attention Deficit Hyperactivity Disorder, Anxiety and Insomnia Using Dexmedetomidine Transdermal Compositions
JP6188934B2 (ja) * 2013-10-07 2017-08-30 テイコク ファーマ ユーエスエー インコーポレーテッド デクスメデトミジン経皮組成物を含む疼痛管理用方法及び組成物
RU2648817C2 (ru) * 2013-10-07 2018-03-28 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Способы и композиции для лечения абстинентных синдромов с использованием неседативных трансдермальных композиций на основе дексмедетомидина
WO2015054058A1 (en) * 2013-10-07 2015-04-16 Teikoku Pharma Usa, Inc. Dexmedetomidine Transdermal Delivery Devices and Methods for Using the Same
ES2847936T3 (es) 2013-10-07 2021-08-04 Teikoku Pharma Usa Inc Métodos y composiciones para el suministro transdérmico de una cantidad no sedante de dexmedetomidina
WO2015093503A1 (ja) 2013-12-18 2015-06-25 丸石製薬株式会社 含水型貼付剤
CN111346072B (zh) * 2018-12-21 2022-05-27 宜昌人福药业有限责任公司 一种透皮给药的药物组合物及其制备方法
US20220211672A1 (en) 2019-05-01 2022-07-07 Clexio Biosciences Ltd. Methods of treating pruritus
KR20220002950A (ko) 2019-05-01 2022-01-07 클렉시오 바이오사이언시스 리미티드 소양증의 치료 방법
TWI772807B (zh) 2019-05-27 2022-08-01 日商救急藥品工業股份有限公司 外用製劑

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783477A (en) 1986-11-11 1988-11-08 Farmos-Yhtyma Oy Anxiolytic composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
GB2206880B (en) * 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative
GB2215206B (en) * 1988-02-29 1991-07-03 Farmos Oy 4-substituted imidazole derivatives useful in perioperative care
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5217718A (en) * 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5304569A (en) * 1989-11-13 1994-04-19 Orion-Yhtyma Oy Compositions and their use in lowering intraocular pressure

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783477A (en) 1986-11-11 1988-11-08 Farmos-Yhtyma Oy Anxiolytic composition

Also Published As

Publication number Publication date
IE67168B1 (en) 1996-03-06
NO934323D0 (no) 1993-11-29
NZ242717A (en) 1994-03-25
LTIP112A (en) 1994-07-15
FI935351A (fi) 1993-11-30
GB2256367B (en) 1995-03-15
WO1992021338A1 (en) 1992-12-10
JP3483881B2 (ja) 2004-01-06
ZA923395B (en) 1993-03-31
CA2110161C (en) 2004-08-03
EP0587819A1 (en) 1994-03-23
GB9211033D0 (en) 1992-07-08
EP0587819B1 (en) 1997-02-26
NO934323L (no) 1993-11-29
JP2003327531A (ja) 2003-11-19
NO303818B1 (no) 1998-09-07
DE69217658T2 (de) 1997-07-03
EE03053B1 (et) 1997-12-15
IE921937A1 (en) 1992-12-02
AU1798192A (en) 1993-01-08
LV10047A (lv) 1994-05-10
GB9111732D0 (en) 1991-07-24
JPH06507888A (ja) 1994-09-08
US5438067A (en) 1995-08-01
FI104948B (fi) 2000-05-15
LV10047B (en) 1995-02-20
DE69217658D1 (de) 1997-04-03
CA2110161A1 (en) 1992-12-10
GB2256367A (en) 1992-12-09
FI935351A0 (fi) 1993-11-30
ATE149090T1 (de) 1997-03-15

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Effective date: 20050529