LT2005087A - Vakcinos kompozicijos gangliozido pagrindu, skirtos įvedimui po oda - Google Patents

Vakcinos kompozicijos gangliozido pagrindu, skirtos įvedimui po oda

Info

Publication number
LT2005087A
LT2005087A LT2005087A LT2005087A LT2005087A LT 2005087 A LT2005087 A LT 2005087A LT 2005087 A LT2005087 A LT 2005087A LT 2005087 A LT2005087 A LT 2005087A LT 2005087 A LT2005087 A LT 2005087A
Authority
LT
Lithuania
Prior art keywords
vssp
vaccine compositions
ganglioside
subcutaneously
compositions
Prior art date
Application number
LT2005087A
Other languages
English (en)
Other versions
LT5351B (lt
Inventor
Luis Enrrique Fernandez Molina
Circle Mesa Pardillo
Original Assignee
Centro De Immunologia Molecular
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro De Immunologia Molecular filed Critical Centro De Immunologia Molecular
Publication of LT2005087A publication Critical patent/LT2005087A/lt
Publication of LT5351B publication Critical patent/LT5351B/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001169Tumor associated carbohydrates
    • A61K39/001171Gangliosides, e.g. GM2, GD2 or GD3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

Aprašytos vakcinos kompozicijos, kuriose gangliozidai ir N. meningitidis OMP buvo sujungti, suformuojant labai mažo dydžio proteoliposomas (VSSP), skirtas įvedimui po oda. Šios kompozicijos nereikalauja bet kokių papildomų adjuvantų naudojimo. Aprašytos kompozicijos įgalina pranašesnį imunologinį gydymą gangliozidais, dalinai N-AcGM3/VSSP ir N-GcGM3/VSSP, injekcijos vietoje sukeliant mažiau agresyvią reakciją. Šias vakcinos kompozicijas galima naudoti paprastesniu būdu ir sveikesniu pacientams.
LT2005087A 2003-02-27 2005-09-21 Vakcinos kompozicijos gangliozido pagrindu, skirtos įvedimui po oda LT5351B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20030047A CU23257A1 (es) 2003-02-27 2003-02-27 COMPOSICIONES VACUNALES A BASE DE GANGLIOSIDOS PARA LA ADMINISTRACION SUBCUTáNEA

Publications (2)

Publication Number Publication Date
LT2005087A true LT2005087A (lt) 2006-04-25
LT5351B LT5351B (lt) 2006-07-25

Family

ID=40091613

Family Applications (1)

Application Number Title Priority Date Filing Date
LT2005087A LT5351B (lt) 2003-02-27 2005-09-21 Vakcinos kompozicijos gangliozido pagrindu, skirtos įvedimui po oda

Country Status (36)

Country Link
US (1) US8591917B2 (lt)
EP (1) EP1604683B1 (lt)
JP (1) JP4729475B2 (lt)
KR (1) KR100703570B1 (lt)
CN (1) CN100418576C (lt)
AR (1) AR043377A1 (lt)
AT (1) ATE353668T1 (lt)
AU (1) AU2004216554B2 (lt)
BR (1) BRPI0407854B1 (lt)
CA (1) CA2535214C (lt)
CL (1) CL2004000374A1 (lt)
CR (1) CR7965A (lt)
CU (1) CU23257A1 (lt)
CY (1) CY1106668T1 (lt)
DE (1) DE602004004768T2 (lt)
DK (1) DK1604683T3 (lt)
EA (1) EA008905B1 (lt)
EC (1) ECSP055978A (lt)
EG (1) EG26446A (lt)
ES (1) ES2280948T3 (lt)
GE (1) GEP20074120B (lt)
HR (1) HRP20050763A2 (lt)
IL (1) IL170355A (lt)
LT (1) LT5351B (lt)
LV (1) LV13400B (lt)
MY (1) MY139811A (lt)
NZ (1) NZ541952A (lt)
PE (1) PE20040955A1 (lt)
PT (1) PT1604683E (lt)
RS (1) RS20050664A (lt)
SI (1) SI1604683T1 (lt)
TN (1) TNSN05209A1 (lt)
TW (1) TWI344372B (lt)
UA (1) UA80859C2 (lt)
UY (1) UY28207A1 (lt)
WO (1) WO2004075811A2 (lt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU24534B1 (es) * 2017-11-06 2021-07-02 Ct Inmunologia Molecular Adyuvantes nano-particulados que contienen variantes sintéticas del gangliósido gm3
CU20170173A7 (es) 2017-12-27 2019-11-04 Ct Inmunologia Molecular Nano-partículas que contienen el gangliósido gm3 como inmunomoduladoras

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965198A (en) 1985-12-24 1990-10-23 Konica Corporation Monoclonal antibody and method of manufacturing hybridoma producing the same
CU22420A1 (es) * 1993-12-29 1996-01-31 Centro Inmunologia Molecular Composicion vacunal para el desarrollo de una respuesta contra gangliosidos n glicolilados y su uso para el tratamiento del cancer
US6149921A (en) * 1993-12-29 2000-11-21 Centro De Inmunologia Molecular Vaccine compositions for eliciting an immune response against N-acetylated gangliosides and their use for cancer treatment
PE20020572A1 (es) * 2000-12-06 2002-07-31 Centro Inmunologia Molecular Preparaciones para potenciar la inmunogenicidad de antigenos poco inmunogenicos
US20030108574A1 (en) * 2001-08-21 2003-06-12 Jennings Harold J. Carbohydrate-based whole cell cancer vaccines

Also Published As

Publication number Publication date
ATE353668T1 (de) 2007-03-15
AU2004216554B2 (en) 2010-05-20
CN100418576C (zh) 2008-09-17
CA2535214A1 (en) 2004-09-10
BRPI0407854A (pt) 2006-02-14
UY28207A1 (es) 2004-09-30
EA200501367A1 (ru) 2006-02-24
GEP20074120B (en) 2007-05-25
ES2280948T3 (es) 2007-09-16
US8591917B2 (en) 2013-11-26
EA008905B1 (ru) 2007-08-31
NZ541952A (en) 2008-06-30
CY1106668T1 (el) 2012-05-23
DE602004004768T2 (de) 2007-10-11
CL2004000374A1 (es) 2005-05-06
IL170355A (en) 2010-05-31
TWI344372B (en) 2011-07-01
HK1087630A1 (zh) 2006-10-20
ECSP055978A (es) 2006-01-16
EP1604683B1 (en) 2007-02-14
DK1604683T3 (da) 2007-06-11
WO2004075811A2 (es) 2004-09-10
MY139811A (en) 2009-10-30
LV13400B (en) 2006-05-20
RS20050664A (en) 2007-11-15
KR20060003857A (ko) 2006-01-11
TNSN05209A1 (en) 2007-06-11
UA80859C2 (en) 2007-11-12
EP1604683A2 (en) 2005-12-14
CN1753691A (zh) 2006-03-29
CA2535214C (en) 2012-01-10
DE602004004768D1 (de) 2007-03-29
BRPI0407854B1 (pt) 2019-02-26
WO2004075811A3 (es) 2004-10-14
AU2004216554A1 (en) 2004-09-10
JP4729475B2 (ja) 2011-07-20
AR043377A1 (es) 2005-07-27
PT1604683E (pt) 2007-05-31
US20070148181A1 (en) 2007-06-28
KR100703570B1 (ko) 2007-04-09
CR7965A (es) 2008-10-29
PE20040955A1 (es) 2005-02-03
SI1604683T1 (sl) 2007-08-31
JP2006519186A (ja) 2006-08-24
HRP20050763A2 (en) 2006-06-30
LT5351B (lt) 2006-07-25
CU23257A1 (es) 2008-01-24
EG26446A (en) 2013-11-07

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Effective date: 20130227