KR970064596A - Hemorrhoid treatment composition for rectal administration - Google Patents

Hemorrhoid treatment composition for rectal administration Download PDF

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Publication number
KR970064596A
KR970064596A KR1019960007638A KR19960007638A KR970064596A KR 970064596 A KR970064596 A KR 970064596A KR 1019960007638 A KR1019960007638 A KR 1019960007638A KR 19960007638 A KR19960007638 A KR 19960007638A KR 970064596 A KR970064596 A KR 970064596A
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KR
South Korea
Prior art keywords
rectal administration
hemorrhoid
hydrophilic natural
composition
therapeutic composition
Prior art date
Application number
KR1019960007638A
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Korean (ko)
Inventor
윤성준
성용길
유제만
최한곤
정재희
Original Assignee
이우용
동화약품공업 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 이우용, 동화약품공업 주식회사 filed Critical 이우용
Priority to KR1019960007638A priority Critical patent/KR970064596A/en
Publication of KR970064596A publication Critical patent/KR970064596A/en

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Abstract

본 발명은 치질치료제, 폴록사머 및 친수성 천연 고분자을 함유하는 직장투여용 치질치료제 조성물에 관한 것이다. 폴록사머와 친수성 천연 고분자를 함유하는 본 발명의 조성물은 상온에서는 액상이고 체내에서는 겔상인 새로운 직장투여용 치질치료제 조성물로서, 생산공정이 단순하기 때문에 제조가 용이하고 경제적이며 투여가 용이하고, 겔강도와 생체부착력이 우수하여 투여 후 체외로 빠져나오지 않으며 대장말단으로 이행되는 단점을 극복하여 계속적으로 약효를 발현할 때까지 직장에 머무를 수 있다.The present invention relates to a hemorrhoid therapeutic composition for rectal administration containing a hemorrhoid therapeutic agent, poloxamer and a hydrophilic natural polymer. The composition of the present invention comprising poloxamer and a hydrophilic natural polymer is liquid at room temperature and gel-like in the body. It is a novel hemorrhoid therapeutic composition for rectal administration. Since the production process is simple, it is easy to manufacture, And bioadhesive ability, it does not escape to the outside of the body after administration and overcomes the disadvantage that it is transferred to the end of the colon, so that it can stay in the work place until the efficacy is continuously exhibited.

폴록사머는 고상타입, 액상타입 및 페이스트 타입에서 선택된 1종 이상의 폴록사머가 조성물 총 함량의 25-40%로 함유되며, 친수성 천연 고분자는 키토산 및 알긴산 나트륨등의 천연 고분자가 총 함량의 0.1-1%로 함유된다.Poloxamers contain at least 25% to 40% of the total composition by weight of one or more poloxamers selected from the solid, liquid and paste types, and the hydrophilic natural polymers include natural polymers such as chitosan and sodium alginate, %.

Description

직장투여용 치질제료제 조성물Hemorrhoid preparations for rectal administration

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is a trivial issue, I did not include the contents of the text.

Claims (4)

치질치료제, 플록사머 25-40% 및 친수성 천연 고분자 0.2-1%를 함유하는 직장투여용 치질치료제 조성물.A hemorrhoid treatment agent, 25-40% of flocamer, and 0.2-1% of a hydrophilic natural polymer. 제1항에 있어서, 치질치료제가 이콜라이배양물임을 특징으로 하는 치질치료제 조성물.2. The hemorrhoid therapeutic composition according to claim 1, wherein the hemorrhoid therapeutic agent is an E. coli culture. 제1항에 있어서, 플록사머가 고상타입, 액상타입 및 페이스트타입에 선택된 1종 또는 2종 이상을 선택되는 것임을 특징으로 하는 직장투여용 치질치료제 조성물.The hemorrhoid therapeutic composition for rectal administration according to claim 1, wherein the floc sharer is selected from one or more selected from the group consisting of solid type, liquid type and paste type. 제1항에 있어서, 친수성 천연 고분자가 키토산 및 알길산 나트륨염에서 1종 또는 2종이 선택되는 것을 특징으로 하는 직장투여용 치질치료제 조성물.The hemorrhoid therapeutic composition for rectal administration according to claim 1, wherein one or two kinds of hydrophilic natural polymers are selected from chitosan and sodium alginate. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: It is disclosed by the contents of the first application.
KR1019960007638A 1996-03-21 1996-03-21 Hemorrhoid treatment composition for rectal administration KR970064596A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019960007638A KR970064596A (en) 1996-03-21 1996-03-21 Hemorrhoid treatment composition for rectal administration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019960007638A KR970064596A (en) 1996-03-21 1996-03-21 Hemorrhoid treatment composition for rectal administration

Publications (1)

Publication Number Publication Date
KR970064596A true KR970064596A (en) 1997-10-13

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KR1019960007638A KR970064596A (en) 1996-03-21 1996-03-21 Hemorrhoid treatment composition for rectal administration

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020071407A (en) * 2001-03-06 2002-09-12 최한곤 Novel composite of liquid suppository for rectal administration

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946870A (en) * 1986-06-06 1990-08-07 Union Carbide Chemicals And Plastics Company Inc. Delivery systems for pharmaceutical or therapeutic actives
JPH05148159A (en) * 1991-09-11 1993-06-15 Euro Celtique Sa Release control composition for medicine
EP0551626A1 (en) * 1991-12-19 1993-07-21 LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. Thermoreversible gel as a liquid pharmaceutical carrier for a galenic formulation
WO1994003157A1 (en) * 1992-07-28 1994-02-17 Poli Industria Chimica S.P.A. Pharmaceutical compositions for transmucosal delivery of peptides
US5292516A (en) * 1990-05-01 1994-03-08 Mediventures, Inc. Body cavity drug delivery with thermoreversible gels containing polyoxyalkylene copolymers
US5346703A (en) * 1990-08-07 1994-09-13 Mediventures, Inc. Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946870A (en) * 1986-06-06 1990-08-07 Union Carbide Chemicals And Plastics Company Inc. Delivery systems for pharmaceutical or therapeutic actives
US5292516A (en) * 1990-05-01 1994-03-08 Mediventures, Inc. Body cavity drug delivery with thermoreversible gels containing polyoxyalkylene copolymers
US5346703A (en) * 1990-08-07 1994-09-13 Mediventures, Inc. Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
JPH05148159A (en) * 1991-09-11 1993-06-15 Euro Celtique Sa Release control composition for medicine
EP0551626A1 (en) * 1991-12-19 1993-07-21 LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. Thermoreversible gel as a liquid pharmaceutical carrier for a galenic formulation
WO1994003157A1 (en) * 1992-07-28 1994-02-17 Poli Industria Chimica S.P.A. Pharmaceutical compositions for transmucosal delivery of peptides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020071407A (en) * 2001-03-06 2002-09-12 최한곤 Novel composite of liquid suppository for rectal administration

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