KR960000246A - Cyclosporine-containing liquid composition - Google Patents

Cyclosporine-containing liquid composition Download PDF

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Publication number
KR960000246A
KR960000246A KR1019940012289A KR19940012289A KR960000246A KR 960000246 A KR960000246 A KR 960000246A KR 1019940012289 A KR1019940012289 A KR 1019940012289A KR 19940012289 A KR19940012289 A KR 19940012289A KR 960000246 A KR960000246 A KR 960000246A
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KR
South Korea
Prior art keywords
liquid composition
containing liquid
cyclosporine
cyclosporin
ethanol
Prior art date
Application number
KR1019940012289A
Other languages
Korean (ko)
Other versions
KR0163210B1 (en
Inventor
김현수
최재윤
이혜원
박영근
최성욱
조강현
Original Assignee
김태훈
주식회사 유한양행
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 김태훈, 주식회사 유한양행 filed Critical 김태훈
Priority to KR1019940012289A priority Critical patent/KR0163210B1/en
Publication of KR960000246A publication Critical patent/KR960000246A/en
Application granted granted Critical
Publication of KR0163210B1 publication Critical patent/KR0163210B1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

본 발명은 사이클로스포린 함유 액제조성물에 관한 것으로, 더욱 상세하게는 사이클로스포린 함유 액제조성물에 있어서, 계면활성제로 타이록사폴을 함유한 것을 특징으로 하는 사이클로스포린의 함유 액제조성물에 관한 것이다.The present invention relates to a cyclosporin-containing liquid composition, and more particularly, to a cyclosporin-containing liquid composition, wherein the cyclosporin-containing liquid composition contains tyloxapol as a surfactant.

Description

사이클로스포린 함유 액제 조성물Cyclosporine-containing liquid composition

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (5)

사이클로스포린 액제 조성물에 있어서, 계면활성제로 타일록사폴을 함유한 것을 특징으로하는 사이클로스포린 함유 액제조성물.A cyclosporin-containing liquid composition, wherein the cyclosporin-containing liquid composition is characterized by containing tiloxapol as a surfactant. 제1항에 있어서, 에탄올과 프로필렌글리콜 또는 식물성유의 혼합물을 더욱 함유한 것을 특징으로 하는 사이클로스포린 함유 액제조성물.The cyclosporine-containing liquid composition according to claim 1, further comprising a mixture of ethanol and propylene glycol or vegetable oil. 제1항 또는 제2항에 있어서, 사이클로스포린과 타일록사폴의 중량비가 1:0.5 내지 1:10인 것을 특징으로 하는 사이클로스포린 함유 액제조성물.The cyclosporine-containing liquid composition according to claim 1 or 2, wherein the weight ratio of cyclosporin to tyloxapol is 1: 0.5 to 1:10. 제2항에 있어서, 에탄올과 프로필렌글리콜 또는 식물성유의 혼합물의 중량비가 1:2 내지 1:10 중량비임을 특징으로 하는 사이클로스포린 함유 액제조성물.The cyclosporine-containing liquid composition according to claim 2, wherein the weight ratio of the mixture of ethanol and propylene glycol or vegetable oil is 1: 2 to 1:10. 사이클로스포린을 에탄올과 프로필렌글리콜 또는 식물성유의 혼합물에 용해시킨다음 타일록사폴을 가하여 제조한 것을 약제학적으로 허용가능한 담체와 함께 내복액제 또는 주사제로 제조하거나 연질캅셀에 충진하여 연질캅셀제로 제조한 것을 특징으로 하는 사이클로스포린 함유 조성물.Cyclosporin is dissolved in a mixture of ethanol and propylene glycol or vegetable oil, and then the addition of tyloxapol is prepared as an oral solution or injection with a pharmaceutically acceptable carrier, or filled into a soft capsule to prepare a soft capsule. Cyclosporine-containing composition. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019940012289A 1994-06-01 1994-06-01 Liquid composition comprising cyclosporin KR0163210B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019940012289A KR0163210B1 (en) 1994-06-01 1994-06-01 Liquid composition comprising cyclosporin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019940012289A KR0163210B1 (en) 1994-06-01 1994-06-01 Liquid composition comprising cyclosporin

Publications (2)

Publication Number Publication Date
KR960000246A true KR960000246A (en) 1996-01-25
KR0163210B1 KR0163210B1 (en) 1998-12-01

Family

ID=19384452

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940012289A KR0163210B1 (en) 1994-06-01 1994-06-01 Liquid composition comprising cyclosporin

Country Status (1)

Country Link
KR (1) KR0163210B1 (en)

Also Published As

Publication number Publication date
KR0163210B1 (en) 1998-12-01

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