KR940005285A - 염증성 장 질환, 염증성 피부 질환 및 자반증의 예방 및 치료용 약제제조를 위한 상보적 억제제의 용도 - Google Patents
염증성 장 질환, 염증성 피부 질환 및 자반증의 예방 및 치료용 약제제조를 위한 상보적 억제제의 용도 Download PDFInfo
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- KR940005285A KR940005285A KR1019930012690A KR930012690A KR940005285A KR 940005285 A KR940005285 A KR 940005285A KR 1019930012690 A KR1019930012690 A KR 1019930012690A KR 930012690 A KR930012690 A KR 930012690A KR 940005285 A KR940005285 A KR 940005285A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Marine Sciences & Fisheries (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Abstract
본 발명은 만성 염증성 장 질환, 염증성 피부질환 및 자반증을 예방 및 치료하기 위한 상보적 억제제, 특히 C1 불활성화제 또는 인자 I 또는 H의 용도에 관한 것이다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (9)
- 염증성 피부 질환 및 장 질환외에도 자반증의 치료 및 예방을 위한 조성물을 제조하기 위한 상보적 억제제의 용도.
- 제1항에 있어서, C1불활성화제, 인자 Ⅰ또는 인자 H 또는 이들의 배합물을 상보적 억제제로서 사용하는 용도.
- 제1항에 있어서, 크론씨 질환 또는 궤양성 결장염의 치료 및 예방을 위한 조성물을 제조하는 용도.
- 제2항에 있어서, 크론씨 질환 또는 궤양성 결장염의 치료 및 예방을 위한 조성물을 제조하는 용도.
- 제1항에 있어서, 농포성 피부병, 피부염균 또는 건선의 치료 및 예방을 위한 조성물을 제조하는 용도.
- 제2항에 있어서, 농포성 피부병, 피부염균 또는 건선의 치료 및 예방을 위한 조성물을 제조하는 용도.
- 제1항에 있어서, C1불활성화제 5내지 5000IU/kg×일 또는 인자 Ⅰ 0.005 내지 100mg/kg×일을 함유하는 조성물을 제조하는 용도.
- 제1항에 있어서, C1불활성화제 5 내지 5000IU/kg×일 또는 인자 Ⅰ0.01 내지 50mg/kg×일 또는 인자 H 0.01 내지 50mg/kg×일을 함유하는 조성물을 제조하는 용도.
- 제1항에 있어서, 정맥내, 근육내 또는 피하로 투여될 수 있는 조성물을 제조하는 용도.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4222534A DE4222534A1 (de) | 1992-07-09 | 1992-07-09 | Verwendung von Komplement-Inhibitoren zur Herstellung eines Arzneimittels zur Prophylaxe und Therapie von entzündlichen Darm- und Hauterkrankungen sowie Purpura |
DEP4222534.5 | 1992-07-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR940005285A true KR940005285A (ko) | 1994-03-21 |
KR100300798B1 KR100300798B1 (ko) | 2001-10-22 |
Family
ID=6462826
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019930012690A KR100300798B1 (ko) | 1992-07-09 | 1993-07-07 | 보체억제제를함유하는염증성장질환염증성피부질환및자반증의예방및치료용약제학적조성물 |
Country Status (12)
Country | Link |
---|---|
US (1) | US6248365B1 (ko) |
EP (1) | EP0585552B1 (ko) |
JP (1) | JP3776940B2 (ko) |
KR (1) | KR100300798B1 (ko) |
AT (1) | ATE231885T1 (ko) |
AU (1) | AU671835B2 (ko) |
CA (1) | CA2100212C (ko) |
DE (2) | DE4222534A1 (ko) |
ES (1) | ES2188586T3 (ko) |
HU (1) | HU220599B1 (ko) |
MX (1) | MX9304110A (ko) |
TW (1) | TW272940B (ko) |
Families Citing this family (37)
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US20020082227A1 (en) * | 1999-09-30 | 2002-06-27 | Scott Henry | Use of oligonucleotides for inhibition of complement activation |
US6820011B2 (en) * | 2001-04-11 | 2004-11-16 | The Regents Of The University Of Colorado | Three-dimensional structure of complement receptor type 2 and uses thereof |
AU2003298650B2 (en) | 2002-11-15 | 2010-03-11 | Musc Foundation For Research Development | Complement receptor 2 targeted complement modulators |
ES2432112T3 (es) | 2004-02-10 | 2013-11-29 | The Regents Of The University Of Colorado, A Body Corporate | Inhibición del factor B, de la vía alternativa del complemento y métodos relacionados |
US8088579B2 (en) | 2005-02-14 | 2012-01-03 | University Of Iowa Research Foundation | Complement factor H for diagnosis of age-related macular degeneration |
CN103505728A (zh) * | 2005-05-26 | 2014-01-15 | 科罗拉多大学评议会法人机构 | 用于治疗外伤性脑损伤、脊髓损伤及相关病症的补体旁路抑制 |
US20070196367A1 (en) * | 2006-02-22 | 2007-08-23 | Valentin Dinu | Methods of preventing and treating Alzheimer's disease, age related macular degeneration and other diseases involving extra-cellular debris through the inhibition of the complement system |
ES2523640T3 (es) | 2006-06-21 | 2014-11-28 | Musc Foundation For Research Development | Direccionamiento del factor H del complemento para el tratamiento de enfermedades |
US7329030B1 (en) | 2006-08-17 | 2008-02-12 | Augux., Ltd. | Assembling structure for LED road lamp and heat dissipating module |
NZ576195A (en) * | 2006-10-10 | 2012-04-27 | Az Univ Amsterdam | Complement inhibition for improved nerve regeneration |
WO2008140653A2 (en) | 2007-03-14 | 2008-11-20 | Taligen Therapeutics, Inc. | Humaneered anti-factor b antibody |
ES2475199T3 (es) | 2008-09-16 | 2014-07-10 | Imuneks Farma Ila� Sanayi Ve Ticaret A.S. | Uso de antagonistas opioides para la preparación de un medicamento en el tratamiento de enfermedades degenerativas de la retina |
US20100086581A1 (en) * | 2008-10-07 | 2010-04-08 | Ernest Bove | Method for purpura reduction and prevention |
WO2011003098A1 (en) | 2009-07-02 | 2011-01-06 | Musc Foundation For Research Development | Methods of stimulating liver regeneration |
EP2482816B8 (en) * | 2009-10-01 | 2016-12-14 | Imuneks Farma Ilaç Sanayi Ve Ticaret A.S. | Topical compositions of naltrexone for treating skin conditions |
CA2795311A1 (en) | 2009-11-05 | 2011-05-12 | Taligen Therapeutics, Inc. | Treatment of paroxysmal nocturnal hemoglobinuria, hemolytic anemias and disease states involving intravascular and extravascular hemolysis |
WO2011113641A1 (en) | 2010-02-12 | 2011-09-22 | Cemm Forschungszentrum Für Molekulare Medizin Gmbh | Complement factor h for oxidative stress disease conditions |
TR201002473A2 (tr) | 2010-03-31 | 2011-09-21 | Mustafa Nevzat �La� Sanay�� A.�. | Herpes zoster hastalığının bır opiat reseptör antagonist kullanılarak tedavi yöntemi. |
JP5986990B2 (ja) | 2010-05-14 | 2016-09-06 | ザ リージェンツ オブ ザ ユニヴァーシティ オブ コロラド,ア ボディ コーポレート | 改善された補体レセプター2(cr2)ターゲティング基 |
MX2012014975A (es) | 2010-06-22 | 2013-03-12 | Univ Colorado Regents | Anticuerpos al fragmento c3d de componente 3 de complemento. |
US20120148542A1 (en) | 2010-12-10 | 2012-06-14 | Lifeline Scientific, Inc. | Machine perfusion with complement inhibitors |
ES2714999T3 (es) | 2011-09-24 | 2019-05-31 | Csl Behring Gmbh | Terapia de combinación que usa inmunoglobulina e inhibidor de C1 |
AU2012318275B2 (en) | 2011-12-22 | 2016-05-19 | Csl Behring Gmbh | Use of C1-inhibitor for the treatment of secondary edema of the central nervous system |
WO2013177035A2 (en) | 2012-05-24 | 2013-11-28 | Alexion Pharmaceuticals, Inc. | Humaneered anti-factor b antibody |
AU2013302441B2 (en) | 2012-08-17 | 2018-05-10 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for detecting complement activation |
US10413620B2 (en) | 2012-08-17 | 2019-09-17 | The Regents Of The University Of Colorado, A Body Corporate | Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging |
US8877808B2 (en) * | 2012-12-06 | 2014-11-04 | Aurin Biotech Inc. | Protection against skin diseases by aurin tricarboxylic acid and its derivatives |
ES2609070T3 (es) | 2013-02-28 | 2017-04-18 | Csl Behring Gmbh | Agente terapéutico para el embolismo de líquido amniótico |
ES2844189T3 (es) | 2013-03-08 | 2021-07-21 | Csl Behring Gmbh | Tratamiento y prevención de lesiones remotas por isquemia-reperfusión |
PL3013366T3 (pl) | 2013-06-28 | 2022-01-17 | Csl Behring Gmbh | Terapia skojarzona z zastosowaniem inhibitora czynnika xii i inhibitora c1 |
CA2986957A1 (en) | 2015-06-03 | 2016-12-08 | Children's Hospital Medical Center | Compositions and methods for treating neonatal biliary atresia |
WO2018024873A1 (en) | 2016-08-05 | 2018-02-08 | Csl Behring Gmbh | Pharmaceutical formulations of c1 esterase inhibitor |
AU2017316513A1 (en) | 2016-08-23 | 2019-03-28 | Csl Behring Gmbh | Method of preventing acute attacks of hereditary angioedema associated with C1 esterase inhibitor deficiency |
AU2018334213A1 (en) | 2017-09-15 | 2020-03-26 | Cedars-Sinai Medical Center | Methods for improving organ function in organ transplant patients |
KR102060891B1 (ko) | 2018-05-23 | 2019-12-30 | 유승선 | 가미사물탕을 유효성분으로 포함하는 색소성자반증 예방 또는 치료용 조성물 |
EP4247416A1 (en) | 2020-11-20 | 2023-09-27 | CSL Behring GmbH | Method for treating antibody-mediated rejection |
WO2023215294A1 (en) * | 2022-05-02 | 2023-11-09 | The Board Of Trustees Of The Leland Stanford Junior University | Complement pathway inhibition for wound healing |
Family Cites Families (8)
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DE2617202A1 (de) * | 1976-04-20 | 1977-11-03 | Troponwerke Dinklage & Co | Oligopeptide als komplementhemmer |
DE3228502A1 (de) * | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung des c1-inaktivators und seine verwendung |
JPH0742235B2 (ja) * | 1985-11-08 | 1995-05-10 | 三共株式会社 | 自己免疫性疾病の予防・治療剤 |
US5157019A (en) * | 1986-03-18 | 1992-10-20 | Monsanto Company | Serine protease inhibitors |
US5166134A (en) * | 1986-12-24 | 1992-11-24 | John Lezdey | Treatment of allergic rhinitis |
EP0353941A3 (en) * | 1988-08-02 | 1991-05-02 | Takeda Chemical Industries, Ltd. | Medicament for psoriasis containing derivatives of 3-aminopyrazolo [3,4-d]pyrimidine |
US5135916A (en) * | 1989-06-12 | 1992-08-04 | Oklahoma Medical Research Foundation | Inhibition of complement mediated inflammatory response |
WO1992010205A1 (en) * | 1990-12-06 | 1992-06-25 | T Cell Sciences, Inc. | Synergistic compositions of soluble complement receptors and compounds that inhibit complement and/or suppress immune activity |
-
1992
- 1992-07-09 DE DE4222534A patent/DE4222534A1/de not_active Withdrawn
-
1993
- 1993-06-18 ES ES93109742T patent/ES2188586T3/es not_active Expired - Lifetime
- 1993-06-18 EP EP93109742A patent/EP0585552B1/de not_active Expired - Lifetime
- 1993-06-18 AT AT93109742T patent/ATE231885T1/de active
- 1993-06-18 DE DE59310327T patent/DE59310327D1/de not_active Expired - Lifetime
- 1993-07-07 KR KR1019930012690A patent/KR100300798B1/ko not_active IP Right Cessation
- 1993-07-07 US US08/087,058 patent/US6248365B1/en not_active Expired - Lifetime
- 1993-07-08 JP JP16886993A patent/JP3776940B2/ja not_active Expired - Lifetime
- 1993-07-08 AU AU41805/93A patent/AU671835B2/en not_active Ceased
- 1993-07-08 MX MX9304110A patent/MX9304110A/es unknown
- 1993-07-08 HU HU9301978A patent/HU220599B1/hu not_active IP Right Cessation
- 1993-07-09 CA CA002100212A patent/CA2100212C/en not_active Expired - Lifetime
- 1993-07-13 TW TW082105551A patent/TW272940B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2100212C (en) | 2005-03-08 |
EP0585552A1 (de) | 1994-03-09 |
EP0585552B1 (de) | 2003-01-29 |
HU220599B1 (hu) | 2002-03-28 |
HUT65754A (en) | 1994-07-28 |
AU671835B2 (en) | 1996-09-12 |
AU4180593A (en) | 1994-01-13 |
ATE231885T1 (de) | 2003-02-15 |
TW272940B (en) | 1996-03-21 |
DE59310327D1 (de) | 2003-03-06 |
ES2188586T3 (es) | 2003-07-01 |
HU9301978D0 (en) | 1993-09-28 |
JP3776940B2 (ja) | 2006-05-24 |
MX9304110A (es) | 1994-03-31 |
KR100300798B1 (ko) | 2001-10-22 |
DE4222534A1 (de) | 1994-01-13 |
JPH06157342A (ja) | 1994-06-03 |
US6248365B1 (en) | 2001-06-19 |
CA2100212A1 (en) | 1994-01-10 |
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