KR890014515A - 트리사이클릭 아민 유도체 - Google Patents

트리사이클릭 아민 유도체 Download PDF

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Publication number
KR890014515A
KR890014515A KR1019890002933A KR890002933A KR890014515A KR 890014515 A KR890014515 A KR 890014515A KR 1019890002933 A KR1019890002933 A KR 1019890002933A KR 890002933 A KR890002933 A KR 890002933A KR 890014515 A KR890014515 A KR 890014515A
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KR
South Korea
Prior art keywords
compound
alkyl
hydrogen
pharmaceutically acceptable
oxygen
Prior art date
Application number
KR1019890002933A
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English (en)
Inventor
둔 칸 로베르트손 라에
카이론 제임스
Original Assignee
에이.지이.제이.베르메렌·에프.지이.엠 헤르만스
악조 엔. 브이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 에이.지이.제이.베르메렌·에프.지이.엠 헤르만스, 악조 엔. 브이. filed Critical 에이.지이.제이.베르메렌·에프.지이.엠 헤르만스
Publication of KR890014515A publication Critical patent/KR890014515A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/08—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/16—Eight-membered rings
    • C07D313/20—Eight-membered rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/16—Eight-membered rings

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음.

Description

트리사이클릭 아민 유도체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (7)

  1. 하기식의 화합물 및 이의 약학적 허용 염.
    상기식에서, X는 산소, 황,또는 -CH2-이며 ; R은 수소 또는 알킬(1-4C)이며 ; R1및 R2는 수소, 히드록시, 알킬(1-6C), 알콕시(1-6C), 할로겐, CF3또는 CN으로부터 선택된 벤조부의 1,2,3 또는 4치환체이며 ; R3및 R4는 수소 또는 알킬(1-6C)이거나 혹은 ; R3및 R4는 그들이 붙은 질소 원자와 함께 헤테로사이클릭 5 또는 6원 링을 형성한다.
  2. 제1항에 있어서, X는 산소인 화합물.
  3. 제1항 또는 제2항에 있어서, -NR3R4부는 N-메틸아미노 또는 N,N-디메틸아미노부인 화합물.
  4. 전술된 항 중 어는 한 항에 있어서, R1및 R2는 두 벤조 부중의 어느 하나에 단일-또는 이중-치환된 패턴을 가지는 화합물.
  5. 제1항에 있어서, 3-클로로-6,7-디하이드로-N-메틸-5H-디벤즈[b,g]옥소신-6-아민 및 그의 약학적 허용 염.
  6. 제1항의 화합물과 1 또는 그 이상의 약학적 허용 담체 또는 희석제를 함유한 약학적 조성물.
  7. 유사화합물 제조용의 공지방법에 따라 제조되는 제1항의 화합물의 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890002933A 1988-03-11 1989-03-10 트리사이클릭 아민 유도체 KR890014515A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88302129 1988-03-11
NL88302129.7 1988-03-11

Publications (1)

Publication Number Publication Date
KR890014515A true KR890014515A (ko) 1989-10-24

Family

ID=8199988

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890002933A KR890014515A (ko) 1988-03-11 1989-03-10 트리사이클릭 아민 유도체

Country Status (10)

Country Link
US (1) US4904688A (ko)
EP (1) EP0332246A1 (ko)
JP (1) JPH024740A (ko)
KR (1) KR890014515A (ko)
AU (1) AU3120589A (ko)
DK (1) DK115289A (ko)
FI (1) FI891099A (ko)
NZ (1) NZ228281A (ko)
PT (1) PT89970A (ko)
ZA (1) ZA891625B (ko)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160033401A (ko) 2014-09-18 2016-03-28 주식회사 엘지생활건강 실리콘 엘라스토머를 포함하는 캡슐, 이를 포함하는 화장료 조성물 및 실리콘 엘라스토머의 제조 방법
KR20200094443A (ko) 2019-01-30 2020-08-07 (주) 제이엠피바이오 젤형 화장료 조성물 제조방법 및 그에 따른 화장료 조성물

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698551A (en) * 1995-04-07 1997-12-16 Novo Nordisk A/S Heterocyclic compounds
FR2739855B1 (fr) * 1995-10-13 1997-11-14 Adir Nouvelles amines heterocycliques tertiaires, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4100173A (en) * 1974-01-04 1978-07-11 Hoffmann-La Roche Inc. Dibenz[b,f]oxepin derivatives
NL7808848A (nl) * 1977-09-19 1979-03-21 Merck & Co Inc Dibenzoa.dcyclo-octeen-5.12-(en 6.12)-iminen.
US4837227A (en) * 1977-12-13 1989-06-06 Hoechst-Roussel Pharmaceuticals, Inc. Aminoalkylthiodibenzoxepins and pharmaceutical use
FR2512024A1 (fr) * 1981-08-27 1983-03-04 Adir Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160033401A (ko) 2014-09-18 2016-03-28 주식회사 엘지생활건강 실리콘 엘라스토머를 포함하는 캡슐, 이를 포함하는 화장료 조성물 및 실리콘 엘라스토머의 제조 방법
KR20200094443A (ko) 2019-01-30 2020-08-07 (주) 제이엠피바이오 젤형 화장료 조성물 제조방법 및 그에 따른 화장료 조성물

Also Published As

Publication number Publication date
EP0332246A1 (en) 1989-09-13
PT89970A (pt) 1989-11-10
US4904688A (en) 1990-02-27
NZ228281A (en) 1990-08-28
FI891099A0 (fi) 1989-03-08
AU3120589A (en) 1989-09-14
FI891099A (fi) 1989-09-12
DK115289A (da) 1989-09-12
DK115289D0 (da) 1989-03-09
ZA891625B (en) 1989-11-29
JPH024740A (ja) 1990-01-09

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