KR880006263A - 신규의 캘시토닌 유도체의 제조방법 - Google Patents

신규의 캘시토닌 유도체의 제조방법 Download PDF

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Publication number
KR880006263A
KR880006263A KR860010384A KR860010384A KR880006263A KR 880006263 A KR880006263 A KR 880006263A KR 860010384 A KR860010384 A KR 860010384A KR 860010384 A KR860010384 A KR 860010384A KR 880006263 A KR880006263 A KR 880006263A
Authority
KR
South Korea
Prior art keywords
compound
ser
thr
leu
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR860010384A
Other languages
English (en)
Korean (ko)
Inventor
카르디나욱스 프란코이스
플레스 아노스
헬무트 부크 로버트
Original Assignee
예안 클라메르, 한스 루돌프 하우스
산도즈 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 예안 클라메르, 한스 루돌프 하우스, 산도즈 리미티드 filed Critical 예안 클라메르, 한스 루돌프 하우스
Publication of KR880006263A publication Critical patent/KR880006263A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR860010384A 1985-12-04 1986-12-03 신규의 캘시토닌 유도체의 제조방법 Ceased KR880006263A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3542859 1985-12-04
DE3542859.7 1986-05-02
DE3614784.2 1986-05-02
DE3614784 1986-05-02

Publications (1)

Publication Number Publication Date
KR880006263A true KR880006263A (ko) 1988-07-22

Family

ID=25838500

Family Applications (1)

Application Number Title Priority Date Filing Date
KR860010384A Ceased KR880006263A (ko) 1985-12-04 1986-12-03 신규의 캘시토닌 유도체의 제조방법

Country Status (20)

Country Link
US (1) US4758550A (https=)
JP (1) JPH085916B2 (https=)
KR (1) KR880006263A (https=)
AU (1) AU600242B2 (https=)
BE (1) BE905849A (https=)
CH (1) CH671229A5 (https=)
DK (1) DK580186A (https=)
ES (1) ES2012510A6 (https=)
FI (1) FI864939A7 (https=)
FR (1) FR2590902B1 (https=)
GB (1) GB2184729B (https=)
GR (1) GR862836B (https=)
HU (1) HUT44794A (https=)
IL (1) IL80846A0 (https=)
IT (1) IT1214754B (https=)
LU (1) LU86697A1 (https=)
NL (1) NL8602950A (https=)
NZ (1) NZ218473A (https=)
PT (1) PT83835B (https=)
SE (1) SE8605189L (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960031478A (ko) * 1995-02-14 1996-09-17 성재갑 유비퀴틴 융합 인간 칼시토닌의 정제방법

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2052642T3 (es) * 1987-07-08 1994-07-16 Mitsubishi Petrochemical Co Nuevo derivado de calcitonina y su sal.
AU609911B2 (en) * 1987-12-16 1991-05-09 Rorer International (Overseas) Inc. 8-glycine,16-x, des-19-leucine-calcitonin
DK163689A (da) * 1988-04-08 1989-10-30 Sandoz Ag Peptidderivater
AU629552B2 (en) * 1988-06-16 1992-10-08 Teijin Limited S-sulfonated calcitonin derivatives
US5026825A (en) * 1988-09-08 1991-06-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Intranasal calcitonin formulations
ES2061809T3 (es) * 1988-11-24 1994-12-16 Mitsubishi Petrochemical Co Un metodo para preparar un derivado de calcitonina.
JPH05508616A (ja) * 1989-02-23 1993-12-02 ローヌー　プーラン　ローラー　インターナショナル（ホウルディングス）インコーポレイテッド 治療用エアロゾル剤
US5204326A (en) * 1989-03-16 1993-04-20 Otsuka Pharmaceutical Co., Ltd. Polypeptide derivatives and calcium metabolism improving agent
DK0423326T3 (da) * 1989-04-21 1999-05-25 Tsumura & Co Hidtil ukendt fysiologisk aktivt peptid og calcium-metabolisme-regulerende middel, der omfatter peptidet som effektiv besta
US5364840A (en) * 1989-12-05 1994-11-15 Vical, Inc. Synthetic calcitonin peptides
US5175146A (en) * 1989-12-05 1992-12-29 Vical, Inc. Synthetic calcitonin peptides
CS89491A3 (en) * 1990-04-09 1992-01-15 Chugai Pharmaceutical Co Ltd Hybrid calcitonin
ES2051647B1 (es) * 1992-12-10 1995-01-16 Lipotec Sa Procedimiento para la preparacion de calcitonina de salmon.
JPH08505393A (ja) * 1992-12-31 1996-06-11 ザイモジェネティクス，インコーポレイティド 誘導体化カルシトニン
US5710244A (en) * 1992-12-31 1998-01-20 Labroo; Virender M. Derivatized calcitonins
WO1995021622A1 (en) * 1994-02-09 1995-08-17 Brigham & Women's Hospital Gel-forming polypeptide derivatives
DE726075T1 (de) * 1995-02-08 1996-12-12 Therapicon Srl Nicht-inorganische pharmazeutische salzige Lösungen zur endonasale Verabreichung
US6034064A (en) * 1995-04-07 2000-03-07 Hoechst Pharmaceuticals & Chemicals K.K. Peptides and therapeutic agent for autoimmune diseases containing the same
US5721207A (en) * 1995-04-18 1998-02-24 Innapharma, Inc. Method for treatment of pain
EP1053001B1 (en) 1998-02-13 2010-12-15 Amylin Pharmaceuticals, Inc. Novel mixed amylin activity compounds
US6936584B1 (en) 1998-02-13 2005-08-30 Amylin Pharmaceuticals, Inc. Mixed amylin activity compounds
US8653238B2 (en) * 2006-02-27 2014-02-18 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for transport of molecules with enhanced release properties across biological barriers
WO2013086143A1 (en) * 2011-12-09 2013-06-13 The Regents Of The University Of California Modified mini-hepcidin peptides and methods of using thereof
WO2013162729A1 (en) 2012-04-24 2013-10-31 The Board Of Trustees Of The Leland Stanford Junior University Method for delivery of small molecules and proteins across the cell wall of algae using molecular transporters

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3926938A (en) * 1974-08-12 1975-12-16 Armour Pharma Synthesis of salmon calcitonin
JPS51128993A (en) * 1975-05-01 1976-11-10 Tanpakushitsu Kenkyu Shiyoureikai Process for preparing new polypeptides
GB1592969A (en) * 1976-09-13 1981-07-15 Armour Pharma Hentriacontapeptides and preparation thereof
WO1984003279A1 (en) * 1983-02-15 1984-08-30 Armour Pharma Des-asparagine-3 calcitonin
US4663309A (en) * 1983-06-29 1987-05-05 University Patents, Inc. Novel peptide hormones with calcitonin-like activity
GB8327346D0 (en) * 1983-10-12 1983-11-16 Morris H R Peptide
US4497732A (en) * 1983-10-21 1985-02-05 Armour Pharmaceutical Company 1A-Endo-glycine-calcitonin
US4537716A (en) * 1983-12-05 1985-08-27 Armour Pharmaceutical Co. Des-serine2 or des-glycine2 -leucine22 calcitonin
US4622386A (en) * 1985-03-28 1986-11-11 Armour Pharmaceutical Company [1,7-di-alanine]calcitonin
US4658014A (en) * 1985-12-20 1987-04-14 Kempe Tomas G Synthetic peptides with calcitonin-like activity
AU7468687A (en) * 1987-06-23 1989-01-05 Armour Pharmaceutical Company (n-acyl, 1,7-di-alanine) calcitonin

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960031478A (ko) * 1995-02-14 1996-09-17 성재갑 유비퀴틴 융합 인간 칼시토닌의 정제방법

Also Published As

Publication number Publication date
DK580186A (da) 1987-06-05
FI864939A0 (fi) 1986-12-03
SE8605189D0 (sv) 1986-12-03
BE905849A (fr) 1987-06-03
FR2590902B1 (fr) 1994-12-23
LU86697A1 (fr) 1987-07-24
FI864939A7 (fi) 1987-06-05
US4758550A (en) 1988-07-19
GB2184729A (en) 1987-07-01
GB2184729B (en) 1990-07-25
GB8628739D0 (en) 1987-01-07
JPS62132898A (ja) 1987-06-16
HUT44794A (en) 1988-04-28
IT8648701A0 (it) 1986-12-04
IT1214754B (it) 1990-01-18
JPH085916B2 (ja) 1996-01-24
PT83835B (pt) 1989-06-30
IL80846A0 (en) 1987-03-31
CH671229A5 (https=) 1989-08-15
NL8602950A (nl) 1987-07-01
SE8605189L (sv) 1987-06-05
NZ218473A (en) 1990-03-27
PT83835A (en) 1986-12-01
DK580186D0 (da) 1986-12-02
FR2590902A1 (fr) 1987-06-05
ES2012510A6 (es) 1990-04-01
AU6606186A (en) 1987-06-11
AU600242B2 (en) 1990-08-09
GR862836B (en) 1987-04-02

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19861203

A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19870928

Comment text: Request for Examination of Application

Patent event code: PA02011R01I

Patent event date: 19861203

Comment text: Patent Application

PG1501 Laying open of application
E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19900926

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 19910131

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 19900926

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I