KR880002355B1 - 카복실산 유도체의 제조방법 - Google Patents

카복실산 유도체의 제조방법 Download PDF

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Publication number
KR880002355B1
KR880002355B1 KR1019840003918A KR840003918A KR880002355B1 KR 880002355 B1 KR880002355 B1 KR 880002355B1 KR 1019840003918 A KR1019840003918 A KR 1019840003918A KR 840003918 A KR840003918 A KR 840003918A KR 880002355 B1 KR880002355 B1 KR 880002355B1
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KR
South Korea
Prior art keywords
ethyl
mixture
carboxylic acid
dihydro
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019840003918A
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English (en)
Korean (ko)
Other versions
KR850001198A (ko
Inventor
에스테베 솔러 조세
Original Assignee
프로베산 에스. 에이.
주앙 에스테베 솔러
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8311250A external-priority patent/FR2548664B1/fr
Application filed by 프로베산 에스. 에이., 주앙 에스테베 솔러 filed Critical 프로베산 에스. 에이.
Publication of KR850001198A publication Critical patent/KR850001198A/ko
Application granted granted Critical
Publication of KR880002355B1 publication Critical patent/KR880002355B1/ko
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
KR1019840003918A 1983-07-06 1984-07-06 카복실산 유도체의 제조방법 Expired KR880002355B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR83/11250 1983-07-06
FR8311250A FR2548664B1 (fr) 1983-07-06 1983-07-06 Derives 7-(pyrrol-l-yl) des acides l-ethyl-1,4-dihydro-4-oxoquinoleine-3-carboxyliques et l-ethyl-1,4-dihydro-4-oxo-(1,8-naphtyridine)-3-carboxyliques substitues, leur preparation et leur application en tant que medicaments
FR8402145A FR2559484B2 (fr) 1983-07-06 1984-02-13 Nouveau derive 7-(pyrrol-1-yl) de l'acide 1-ethyl-1,4-dihydro-4-oxo-(1,8-naphtyridin)-3-carboxylique, sa preparation et son application en tant que medicament
FR84/02145 1984-02-13

Publications (2)

Publication Number Publication Date
KR850001198A KR850001198A (ko) 1985-03-16
KR880002355B1 true KR880002355B1 (ko) 1988-10-29

Family

ID=26223521

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840003918A Expired KR880002355B1 (ko) 1983-07-06 1984-07-06 카복실산 유도체의 제조방법

Country Status (21)

Country Link
US (1) US4552882A (https=)
EP (1) EP0134165B1 (https=)
KR (1) KR880002355B1 (https=)
AT (1) ATE34982T1 (https=)
AU (1) AU564326B2 (https=)
BR (1) BR8403342A (https=)
CA (1) CA1256876A (https=)
CS (1) CS244139B2 (https=)
DD (1) DD223150A5 (https=)
DE (1) DE3471934D1 (https=)
DK (1) DK163126C (https=)
ES (1) ES533749A0 (https=)
FR (1) FR2559484B2 (https=)
GR (1) GR81646B (https=)
HK (1) HK10491A (https=)
HU (1) HU189916B (https=)
MX (1) MX156436A (https=)
NO (1) NO163329C (https=)
PL (1) PL143730B1 (https=)
PT (1) PT78854B (https=)
YU (1) YU43577B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2574404B1 (fr) * 1984-12-12 1987-04-24 Provesan Sa Derives 1-substitues de l'acide 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoleine-3-carboxylique, leur preparation et leur application en tant que medicaments
DE3519286A1 (de) * 1985-05-30 1986-12-04 Bayer Ag, 5090 Leverkusen 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4692454A (en) * 1986-02-03 1987-09-08 Warner-Lambert Company Opthalmic use of quinolone antibiotics
DE3615767A1 (de) * 1986-05-10 1987-11-12 Bayer Ag Verfahren zur herstellung von 4-hydroxy-chinolin-3-carbonsaeuren
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
ES2051225B1 (es) * 1992-07-23 1994-12-16 Esteve Quimica Sa Procedimiento de preparacion del acido 1-etil-6-fluoro-7-(pirrol-1-il) -1,4-dihidro-4-oxo-3-quinoleincarboxilico.
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
EP2671507A3 (en) 2005-04-28 2014-02-19 Proteus Digital Health, Inc. Pharma-informatics system
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
CA2752373C (en) 2009-02-20 2017-10-10 To-Bbb Holding B.V. Glutathione-based drug delivery system
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN104803975A (zh) * 2015-04-24 2015-07-29 河南大学 一种氨甲基三唑取代的二氟喹诺酮羧酸类衍生物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU168497B (https=) * 1972-12-18 1976-05-28
JPS5233694A (en) * 1975-09-09 1977-03-14 Dai Ichi Seiyaku Co Ltd Process for preparation of 6_nitro-1,8-naphthyridine derivatives
AR223983A1 (es) * 1978-08-25 1981-10-15 Dainippon Pharmaceutical Co Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico
JPS5649382A (en) * 1979-09-28 1981-05-02 Dainippon Pharmaceut Co Ltd 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt

Also Published As

Publication number Publication date
DD223150A5 (de) 1985-06-05
ES8503335A1 (es) 1985-03-01
US4552882A (en) 1985-11-12
PL248545A1 (en) 1985-07-16
CS528584A2 (en) 1985-08-31
PL143730B1 (en) 1988-03-31
YU119084A (en) 1986-12-31
AU564326B2 (en) 1987-08-06
FR2559484B2 (fr) 1986-09-26
AU2942584A (en) 1985-01-10
HUT34482A (en) 1985-03-28
MX156436A (es) 1988-08-22
FR2559484A2 (fr) 1985-08-16
NO163329C (no) 1990-05-09
PT78854A (fr) 1984-08-01
HK10491A (en) 1991-02-13
EP0134165B1 (fr) 1988-06-08
EP0134165A3 (en) 1985-10-09
YU43577B (en) 1989-08-31
NO163329B (no) 1990-01-29
KR850001198A (ko) 1985-03-16
BR8403342A (pt) 1985-06-18
DK331384A (da) 1985-01-07
CS244139B2 (en) 1986-07-17
CA1256876A (en) 1989-07-04
DK331384D0 (da) 1984-07-05
ATE34982T1 (de) 1988-06-15
DE3471934D1 (en) 1988-07-14
DK163126B (da) 1992-01-20
PT78854B (fr) 1986-10-23
NO842717L (no) 1985-01-07
DK163126C (da) 1992-06-15
GR81646B (https=) 1984-12-11
EP0134165A2 (fr) 1985-03-13
ES533749A0 (es) 1985-03-01
HU189916B (en) 1986-08-28

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