KR20240125943A - 신경능 세포의 배양 방법 및 제조 방법 - Google Patents
신경능 세포의 배양 방법 및 제조 방법 Download PDFInfo
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- KR20240125943A KR20240125943A KR1020247023032A KR20247023032A KR20240125943A KR 20240125943 A KR20240125943 A KR 20240125943A KR 1020247023032 A KR1020247023032 A KR 1020247023032A KR 20247023032 A KR20247023032 A KR 20247023032A KR 20240125943 A KR20240125943 A KR 20240125943A
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0662—Stem cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
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- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPJP-P-2021-212693 | 2021-12-27 | ||
| JP2021212693 | 2021-12-27 | ||
| PCT/JP2022/047993 WO2023127824A1 (ja) | 2021-12-27 | 2022-12-26 | 神経堤細胞の培養方法及び製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20240125943A true KR20240125943A (ko) | 2024-08-20 |
Family
ID=86998927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247023032A Pending KR20240125943A (ko) | 2021-12-27 | 2022-12-26 | 신경능 세포의 배양 방법 및 제조 방법 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250092359A1 (https=) |
| EP (1) | EP4458954A4 (https=) |
| JP (1) | JPWO2023127824A1 (https=) |
| KR (1) | KR20240125943A (https=) |
| CN (1) | CN118475685A (https=) |
| CA (1) | CA3244444A1 (https=) |
| WO (1) | WO2023127824A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117448267B (zh) * | 2023-12-22 | 2024-08-02 | 上海元戊医学技术有限公司 | 一种用于骨关节炎药物的间充质干细胞构建方法与应用 |
| CN117431209B (zh) * | 2023-12-22 | 2024-07-26 | 上海元戊医学技术有限公司 | 通过神经嵴细胞系制备间充质干细胞的方法及作为骨关节炎药物的应用 |
| CN119570722B (zh) * | 2024-12-10 | 2025-11-14 | 成都汇欣华西慢性病医学研究院有限公司 | 一种基于神经嵴类器官的间充质干细胞制备方法及应用 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011149762A2 (en) | 2010-05-25 | 2011-12-01 | Memorial Sloan-Kettering Cancer Center | Method of nociceptor differentiantion of human embryonic stem cells and uses thereof |
| WO2016027850A1 (ja) | 2014-08-21 | 2016-02-25 | 味の素株式会社 | 間葉系幹細胞用培地 |
| WO2016114285A1 (ja) | 2015-01-15 | 2016-07-21 | 国立大学法人大阪大学 | 多能性幹細胞からの角膜上皮細胞の分化誘導 |
| WO2018143312A1 (ja) | 2017-01-31 | 2018-08-09 | 国立大学法人大阪大学 | 多能性幹細胞の分化制御方法 |
| WO2018199142A1 (ja) | 2017-04-27 | 2018-11-01 | 国立大学法人京都大学 | 神経堤細胞および交感神経細胞の製造方法 |
| WO2019107485A1 (ja) | 2017-11-30 | 2019-06-06 | 国立大学法人京都大学 | 細胞の培養方法 |
| WO2020230832A1 (ja) | 2019-05-15 | 2020-11-19 | 味の素株式会社 | 神経堤細胞または角膜上皮細胞の純化方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US6280718B1 (en) | 1999-11-08 | 2001-08-28 | Wisconsin Alumni Reasearch Foundation | Hematopoietic differentiation of human pluripotent embryonic stem cells |
| WO2002101057A1 (fr) | 2001-06-08 | 2002-12-19 | Dnavec Research Inc. | Transfert genique dans des cellules souches embryonnaires de primate a l'aide d'un virus de l'immunodeficience simienne de pseudo type vsv-g utilise comme vecteur |
| WO2016104574A1 (ja) * | 2014-12-24 | 2016-06-30 | 国立大学法人京都大学 | 異所性骨化の予防・治療剤及びそのスクリーニング方法 |
| WO2020250913A1 (ja) * | 2019-06-11 | 2020-12-17 | 国立大学法人京都大学 | 腎間質細胞の製造方法 |
| CN110241084B (zh) * | 2019-06-13 | 2024-08-16 | 香港中文大学深圳研究院 | 神经嵴细胞培养液、神经嵴间充质干细胞的制备方法及神经嵴间充质干细胞的应用 |
| US20220340868A1 (en) * | 2019-08-06 | 2022-10-27 | Kao Corporation | Method for preparing skin-derived pluripotent precursor cells |
-
2022
- 2022-12-26 JP JP2023571027A patent/JPWO2023127824A1/ja active Pending
- 2022-12-26 CA CA3244444A patent/CA3244444A1/en active Pending
- 2022-12-26 WO PCT/JP2022/047993 patent/WO2023127824A1/ja not_active Ceased
- 2022-12-26 US US18/724,170 patent/US20250092359A1/en active Pending
- 2022-12-26 CN CN202280086133.8A patent/CN118475685A/zh active Pending
- 2022-12-26 EP EP22916047.8A patent/EP4458954A4/en active Pending
- 2022-12-26 KR KR1020247023032A patent/KR20240125943A/ko active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011149762A2 (en) | 2010-05-25 | 2011-12-01 | Memorial Sloan-Kettering Cancer Center | Method of nociceptor differentiantion of human embryonic stem cells and uses thereof |
| WO2016027850A1 (ja) | 2014-08-21 | 2016-02-25 | 味の素株式会社 | 間葉系幹細胞用培地 |
| WO2016114285A1 (ja) | 2015-01-15 | 2016-07-21 | 国立大学法人大阪大学 | 多能性幹細胞からの角膜上皮細胞の分化誘導 |
| WO2018143312A1 (ja) | 2017-01-31 | 2018-08-09 | 国立大学法人大阪大学 | 多能性幹細胞の分化制御方法 |
| WO2018199142A1 (ja) | 2017-04-27 | 2018-11-01 | 国立大学法人京都大学 | 神経堤細胞および交感神経細胞の製造方法 |
| WO2019107485A1 (ja) | 2017-11-30 | 2019-06-06 | 国立大学法人京都大学 | 細胞の培養方法 |
| WO2020230832A1 (ja) | 2019-05-15 | 2020-11-19 | 味の素株式会社 | 神経堤細胞または角膜上皮細胞の純化方法 |
Non-Patent Citations (4)
| Title |
|---|
| Alan W. Leung et al., "WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate", Development, 143: 398-410, 2016 |
| Laura S. Gammill et al., "Division of labor during trunk neural crest development", Dev Biol. 2010 Aug 15; 344(2): 555-565 |
| Makoto Fukuta et al., "Derivation of Mesenchymal Stromal Cells from Pluripotent Stem Cells through a Neural Crest Lineage using Small Molecule Compounds with Defined Media", PLoS One. 2014 Dec 2; 9(12): e112291 |
| Shun Shibata et al., "Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages", Cell Reports, 2018, 25(6): 1668-1679 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2023127824A1 (https=) | 2023-07-06 |
| CA3244444A1 (en) | 2025-02-27 |
| EP4458954A4 (en) | 2026-04-29 |
| EP4458954A1 (en) | 2024-11-06 |
| WO2023127824A1 (ja) | 2023-07-06 |
| US20250092359A1 (en) | 2025-03-20 |
| CN118475685A (zh) | 2024-08-09 |
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