KR20240125080A - 생체분자 프로브를 사용하는 조직의 멀티플렉스 질량 분석 이미징을 위한 신규한 광절단 가능한 질량 태그 - Google Patents

생체분자 프로브를 사용하는 조직의 멀티플렉스 질량 분석 이미징을 위한 신규한 광절단 가능한 질량 태그 Download PDF

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KR20240125080A
KR20240125080A KR1020247026785A KR20247026785A KR20240125080A KR 20240125080 A KR20240125080 A KR 20240125080A KR 1020247026785 A KR1020247026785 A KR 1020247026785A KR 20247026785 A KR20247026785 A KR 20247026785A KR 20240125080 A KR20240125080 A KR 20240125080A
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mass
msi
tissue
nucleic acid
probe
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마를 제이. 림
가르게이 야그니크
케니스 제이. 로스차일드
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암베르겐, 인크.
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/6841In situ hybridisation
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • G01N33/531Production of immunochemical test materials
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    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
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    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
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    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • G01N33/6851Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • HELECTRICITY
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    • H01J49/02Details
    • H01J49/10Ion sources; Ion guns
    • H01J49/16Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
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KR1020247026785A 2020-10-29 2021-08-11 생체분자 프로브를 사용하는 조직의 멀티플렉스 질량 분석 이미징을 위한 신규한 광절단 가능한 질량 태그 Pending KR20240125080A (ko)

Applications Claiming Priority (4)

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US202063106990P 2020-10-29 2020-10-29
US63/106,990 2020-10-29
PCT/US2021/045520 WO2022093357A1 (en) 2020-10-29 2021-08-11 Novel photocleavable mass-tags for multiplexed mass spectrometric imaging of tissues using biomolecular probes
KR1020237014451A KR20230127204A (ko) 2020-10-29 2021-08-11 생체분자 프로브를 사용하는 조직의 멀티플렉스 질량 분석 이미징을 위한 신규한 광절단 가능한 질량 태그

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KR1020237014451A Division KR20230127204A (ko) 2020-10-29 2021-08-11 생체분자 프로브를 사용하는 조직의 멀티플렉스 질량 분석 이미징을 위한 신규한 광절단 가능한 질량 태그

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KR1020237014451A Pending KR20230127204A (ko) 2020-10-29 2021-08-11 생체분자 프로브를 사용하는 조직의 멀티플렉스 질량 분석 이미징을 위한 신규한 광절단 가능한 질량 태그

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US (12) US12181481B2 (https=)
EP (1) EP4237839A4 (https=)
JP (1) JP7752686B2 (https=)
KR (2) KR20240125080A (https=)
CN (1) CN116457664B (https=)
AU (2) AU2021372349B2 (https=)
CA (1) CA3195979A1 (https=)
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